Click here to switch to the map view.

The map label for this gene is sucC [H]

Identifier: 161523833

GI number: 161523833

Start: 716912

End: 718078

Strand: Direct

Name: sucC [H]

Synonym: Bmul_0653

Alternate gene names: 161523833

Gene position: 716912-718078 (Clockwise)

Preceding gene: 161523832

Following gene: 161523834

Centisome position: 20.79

GC content: 62.55

Gene sequence:

>1167_bases
ATGAAGATTCACGAGTACCAGGGTAAGGAAATCCTGCGGAAATTCGGAGTCGCGGTACCGCGCGGCAAGCCGGCGTTCTC
GGTGGACGAGGCCGTCAAGGTGGCGGAAGAGCTCGGTGGCCCGGTGTGGGTCGTCAAGGCTCAGATTCACGCGGGTGGCC
GCGGCAAGGGCGGCGGCGTGAAGGTCGCGAAGTCGCTCGAGCAGGTGCGCGAATACGCGAACCAGATCCTCGGCATGCAG
CTGGTCACGCACCAGACGGGCCCGGAAGGCCAGAAGGTGAACCGCCTGCTGATCGAAGAAGGCGCCGACATCAAGCAGGA
ACTGTATGTCAGCCTCGTCGTCGACCGCATCTCGCAGAAGATCGTGCTGATGGGTTCGAGCGAAGGCGGCATGGACATCG
AAGAAGTCGCCGAAAAGCACCCGGAACTGATCCACAAGGTCATCGTCGAGCCGTCGACGGGCCTGCTCGACTCGCAGGCA
GACGACCTCGCCACGAAGATCGGCGTGCCGGCTGCTTCGATTCCGCAAGCACGCGCGATCCTGCAAGGCCTGTACAAGGC
ATTCTGGGAAACCGACGCATCGCTGGCTGAAATCAACCCGCTGAACGTTTCCGGCGACGGCAAGGTCGTCGCACTCGACG
CGAAGTTCAACTTCGACTCGAACGCGCTGTTCCGTCACCCGGAAATCGTCGCGTACCGCGATCTGGACGAAGAAGATCCG
GCTGAAATCGAAGCGTCGAAGTTCGACCTCGCGTACATCTCGCTCGACGGCAACATCGGCTGCCTCGTGAACGGCGCAGG
CCTCGCGATGGCGACGATGGACACGATCAAGCTGTTCGGCGGCGAACCGGCGAACTTCCTGGACGTCGGCGGTGGCGCGA
CGACCGAGAAGGTCACCGAAGCGTTCAAGCTGATGCTGAAGAACCCGGGTCTGAAGGCGATCCTCGTGAACATCTTCGGC
GGCATCATGCGCTGCGACGTGATCGCGGAAGGCGTGATCGCCGGTTCGAAGGCCGTGAACCTGAACGTGCCGCTCGTCGT
GCGCATGAAGGGCACGAACGAGGACCTGGGCAAGAAGATGCTGGCCGATTCCGGCCTGCCGATCATCTCGGCGGACAGCA
TGGAAGAGGCTGCGCAGAAGGTGGTCGCGGCTGCCGCAGGCAAGTAA

Upstream 100 bases:

>100_bases
GCCGGCCGGAGTCGGGCGGCACGAAGGAATGAACGGAAATCATTCAAAGAAGCGTCTTAAGCGACTTTTCATCCAACTCT
CAGACTGAAGGGAATCACGC

Downstream 100 bases:

>100_bases
AGAAGCGCCCCCGGACCTGGCGCCATGCGCCAGGCTCCGCGGGGGGTCAAGAAAACTTGGGGCGGCCCGGCGTTTTCTTG
GCGCGCTAATGAACACGCAT

Product: succinyl-CoA synthetase subunit beta

Products: NA

Alternate protein names: Succinyl-CoA synthetase subunit beta; SCS-beta [H]

Number of amino acids: Translated: 388; Mature: 388

Protein sequence:

>388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYANQILGMQ
LVTHQTGPEGQKVNRLLIEEGADIKQELYVSLVVDRISQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDSQA
DDLATKIGVPAASIPQARAILQGLYKAFWETDASLAEINPLNVSGDGKVVALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLADSGLPIISADSMEEAAQKVVAAAAGK

Sequences:

>Translated_388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYANQILGMQ
LVTHQTGPEGQKVNRLLIEEGADIKQELYVSLVVDRISQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDSQA
DDLATKIGVPAASIPQARAILQGLYKAFWETDASLAEINPLNVSGDGKVVALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLADSGLPIISADSMEEAAQKVVAAAAGK
>Mature_388_residues
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGVKVAKSLEQVREYANQILGMQ
LVTHQTGPEGQKVNRLLIEEGADIKQELYVSLVVDRISQKIVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDSQA
DDLATKIGVPAASIPQARAILQGLYKAFWETDASLAEINPLNVSGDGKVVALDAKFNFDSNALFRHPEIVAYRDLDEEDP
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTEAFKLMLKNPGLKAILVNIFG
GIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKMLADSGLPIISADSMEEAAQKVVAAAAGK

Specific function: Tricarboxylic acid cycle. [C]

COG id: COG0045

COG function: function code C; Succinyl-CoA synthetase, beta subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ATP-grasp domain [H]

Homologues:

Organism=Homo sapiens, GI11321583, Length=389, Percent_Identity=48.0719794344473, Blast_Score=355, Evalue=4e-98,
Organism=Homo sapiens, GI157779135, Length=383, Percent_Identity=46.7362924281984, Blast_Score=332, Evalue=4e-91,
Organism=Homo sapiens, GI294862256, Length=359, Percent_Identity=46.7966573816156, Blast_Score=313, Evalue=2e-85,
Organism=Escherichia coli, GI1786948, Length=388, Percent_Identity=52.8350515463918, Blast_Score=402, Evalue=1e-113,
Organism=Caenorhabditis elegans, GI17539378, Length=393, Percent_Identity=45.29262086514, Blast_Score=338, Evalue=3e-93,
Organism=Caenorhabditis elegans, GI17567829, Length=390, Percent_Identity=43.5897435897436, Blast_Score=324, Evalue=6e-89,
Organism=Saccharomyces cerevisiae, GI6321683, Length=392, Percent_Identity=45.4081632653061, Blast_Score=350, Evalue=3e-97,
Organism=Drosophila melanogaster, GI21356231, Length=392, Percent_Identity=44.3877551020408, Blast_Score=327, Evalue=7e-90,
Organism=Drosophila melanogaster, GI161078106, Length=392, Percent_Identity=44.1326530612245, Blast_Score=318, Evalue=5e-87,
Organism=Drosophila melanogaster, GI24645208, Length=392, Percent_Identity=44.1326530612245, Blast_Score=318, Evalue=5e-87,
Organism=Drosophila melanogaster, GI281361397, Length=393, Percent_Identity=44.2748091603053, Blast_Score=317, Evalue=1e-86,
Organism=Drosophila melanogaster, GI281361395, Length=393, Percent_Identity=44.2748091603053, Blast_Score=317, Evalue=1e-86,

Paralogues:

None

Copy number: 340 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2361 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 3,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011761
- InterPro:   IPR013650
- InterPro:   IPR013815
- InterPro:   IPR013816
- InterPro:   IPR005811
- InterPro:   IPR017866
- InterPro:   IPR005809
- InterPro:   IPR016102 [H]

Pfam domain/function: PF08442 ATP-grasp_2; PF00549 Ligase_CoA [H]

EC number: =6.2.1.5 [H]

Molecular weight: Translated: 41222; Mature: 41222

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: PS50975 ATP_GRASP ; PS00063 ALDOKETO_REDUCTASE_3 ; PS01217 SUCCINYL_COA_LIG_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSLEQVREYANQILGMQLVTHQTGPEGQKVNRLLIEEGADIKQELYVSLVVDRISQK
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCE
IVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDSQADDLATKIGVPAASIPQARAI
EEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQGLYKAFWETDASLAEINPLNVSGDGKVVALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCHHCCCCEEECCCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEHHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHH
LADSGLPIISADSMEEAAQKVVAAAAGK
HHCCCCCEEECCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKIHEYQGKEILRKFGVAVPRGKPAFSVDEAVKVAEELGGPVWVVKAQIHAGGRGKGGGV
CCCCCCCCHHHHHHHCCCCCCCCCCCCHHHHHHHHHHCCCCEEEEEEEEECCCCCCCCCH
KVAKSLEQVREYANQILGMQLVTHQTGPEGQKVNRLLIEEGADIKQELYVSLVVDRISQK
HHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHCCE
IVLMGSSEGGMDIEEVAEKHPELIHKVIVEPSTGLLDSQADDLATKIGVPAASIPQARAI
EEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHCCCCCCCHHHHHH
LQGLYKAFWETDASLAEINPLNVSGDGKVVALDAKFNFDSNALFRHPEIVAYRDLDEEDP
HHHHHHHHHCCCCCHHCCCCEEECCCCEEEEEEEEECCCCCCEECCCCEEEECCCCCCCC
AEIEASKFDLAYISLDGNIGCLVNGAGLAMATMDTIKLFGGEPANFLDVGGGATTEKVTE
CCCCCCEEEEEEEEECCCEEEEEECCCEEHHHHHHHHHCCCCCCCEEECCCCCCHHHHHH
AFKLMLKNPGLKAILVNIFGGIMRCDVIAEGVIAGSKAVNLNVPLVVRMKGTNEDLGKKM
HHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEECCCEEEEECCCCHHHHHHH
LADSGLPIISADSMEEAAQKVVAAAAGK
HHCCCCCEEECCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA