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The map label for this gene is yegW [H]

Identifier: 161523658

GI number: 161523658

Start: 521486

End: 522220

Strand: Direct

Name: yegW [H]

Synonym: Bmul_0478

Alternate gene names: 161523658

Gene position: 521486-522220 (Clockwise)

Preceding gene: 161523657

Following gene: 161523659

Centisome position: 15.12

GC content: 71.56

Gene sequence:

>735_bases
ATGGAAACCGGCTGGTCCGAACTGGCGCCCGATCCGCTCAGCGATACGCCGCTCTATCTGCAGCTCGCCCGCAAGCTGGC
CGGCGCGATTCACGGCGGCACCTGGCGGGCCGGCGAGGCGCTGCCGTCGGAGCGCGCGCTGTCGGCGTCGGTCGGCGTCT
CGCGGATCACGGCGCGACGTGCGCTCGCGCTGCTGGTCGAGCAGGGCCTCATCAGACGCTCGCGCGGCGCGGGCAGCTTC
ATCACGCCGCGCGTCGCCGATCCGCTGTCGCGGCTCGTCGGCTTCACCGCGAAGATGCGCCAGCGCGGCTTCATGCCCGA
TTCGGTCTGGCTCGAGCGCCGGCTGCGCGCGGCGACGCGCGCGGAGCTCAGGCATCTCGGCCTCGCGCCGGGCGCGACGG
TTGCGCGGCTCGAACGGCTGCGCCGCGCGGACGGCATCGTGATGGCCGTCGAGCATTCGACGCTGCCGGCCGCGGTCGTG
CCCGATCCGCTCGCGCTCGGCGCGTCGCTGTACGAATACCTCGAAGCGCGCGGCATGAACGTGGTGCGCGCGCTGCAGCA
CTTTCGCGCGGTCAACGCGACGCGCGAGATCGCGAAGTGGATGGCCGTGAAGCCGGGCGCCGCGCTGCTCGTGATCACGC
GCATCGGCTACGGTGCCGACCAGCGCGCGATCGAAGTGACCGAAACGTATTGCCGCGACGACTACTACGACTTCGTCGCC
GAACTGAAACGCTGA

Upstream 100 bases:

>100_bases
TTTCGACGCGCTAATACCAGTTCGTTGACTGGTATTATGGTGGTTATATAATGCGTTCACTTTCGACGGCTCGCGGTCGT
CGTCCGACACCCGGAGGCAC

Downstream 100 bases:

>100_bases
CGCGCGACACTGCGCGCCGACATGCAACCGATTCGCACATCACGACGCGGATGCCCGCGTCACCCGATCCTCAAGAGAAC
GTCATGCTGACTGGCAACAT

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 244; Mature: 244

Protein sequence:

>244_residues
METGWSELAPDPLSDTPLYLQLARKLAGAIHGGTWRAGEALPSERALSASVGVSRITARRALALLVEQGLIRRSRGAGSF
ITPRVADPLSRLVGFTAKMRQRGFMPDSVWLERRLRAATRAELRHLGLAPGATVARLERLRRADGIVMAVEHSTLPAAVV
PDPLALGASLYEYLEARGMNVVRALQHFRAVNATREIAKWMAVKPGAALLVITRIGYGADQRAIEVTETYCRDDYYDFVA
ELKR

Sequences:

>Translated_244_residues
METGWSELAPDPLSDTPLYLQLARKLAGAIHGGTWRAGEALPSERALSASVGVSRITARRALALLVEQGLIRRSRGAGSF
ITPRVADPLSRLVGFTAKMRQRGFMPDSVWLERRLRAATRAELRHLGLAPGATVARLERLRRADGIVMAVEHSTLPAAVV
PDPLALGASLYEYLEARGMNVVRALQHFRAVNATREIAKWMAVKPGAALLVITRIGYGADQRAIEVTETYCRDDYYDFVA
ELKR
>Mature_244_residues
METGWSELAPDPLSDTPLYLQLARKLAGAIHGGTWRAGEALPSERALSASVGVSRITARRALALLVEQGLIRRSRGAGSF
ITPRVADPLSRLVGFTAKMRQRGFMPDSVWLERRLRAATRAELRHLGLAPGATVARLERLRRADGIVMAVEHSTLPAAVV
PDPLALGASLYEYLEARGMNVVRALQHFRAVNATREIAKWMAVKPGAALLVITRIGYGADQRAIEVTETYCRDDYYDFVA
ELKR

Specific function: Unknown

COG id: COG2188

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788418, Length=228, Percent_Identity=32.8947368421053, Blast_Score=135, Evalue=2e-33,
Organism=Escherichia coli, GI87082252, Length=230, Percent_Identity=29.1304347826087, Blast_Score=94, Evalue=9e-21,
Organism=Escherichia coli, GI1786950, Length=226, Percent_Identity=29.2035398230088, Blast_Score=93, Evalue=1e-20,
Organism=Escherichia coli, GI1790540, Length=240, Percent_Identity=27.0833333333333, Blast_Score=71, Evalue=5e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000524
- InterPro:   IPR011663
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00392 GntR; PF07702 UTRA [H]

EC number: NA

Molecular weight: Translated: 26799; Mature: 26799

Theoretical pI: Translated: 10.66; Mature: 10.66

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METGWSELAPDPLSDTPLYLQLARKLAGAIHGGTWRAGEALPSERALSASVGVSRITARR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALALLVEQGLIRRSRGAGSFITPRVADPLSRLVGFTAKMRQRGFMPDSVWLERRLRAATR
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AELRHLGLAPGATVARLERLRRADGIVMAVEHSTLPAAVVPDPLALGASLYEYLEARGMN
HHHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHCCCHHHHHHHHHHHHHHCCHH
VVRALQHFRAVNATREIAKWMAVKPGAALLVITRIGYGADQRAIEVTETYCRDDYYDFVA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHH
ELKR
HHCC
>Mature Secondary Structure
METGWSELAPDPLSDTPLYLQLARKLAGAIHGGTWRAGEALPSERALSASVGVSRITARR
CCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHHH
ALALLVEQGLIRRSRGAGSFITPRVADPLSRLVGFTAKMRQRGFMPDSVWLERRLRAATR
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
AELRHLGLAPGATVARLERLRRADGIVMAVEHSTLPAAVVPDPLALGASLYEYLEARGMN
HHHHHHCCCCCHHHHHHHHHHHHCCEEEEEECCCCCCHHCCCHHHHHHHHHHHHHHCCHH
VVRALQHFRAVNATREIAKWMAVKPGAALLVITRIGYGADQRAIEVTETYCRDDYYDFVA
HHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHCCHHHHHHH
ELKR
HHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]