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The map label for this gene is yjcC [H]

Identifier: 161523539

GI number: 161523539

Start: 397451

End: 398722

Strand: Direct

Name: yjcC [H]

Synonym: Bmul_0359

Alternate gene names: 161523539

Gene position: 397451-398722 (Clockwise)

Preceding gene: 161523537

Following gene: 161523540

Centisome position: 11.53

GC content: 70.68

Gene sequence:

>1272_bases
ATGACGACCGAGCAACAGGAGCGACCGGTTGTCGCGTCGCCGTACCGTTTCGAGCGGGAAGTGAGTTCCGGCTTCGAGCG
GTTCGCGACGCGGCACCGCGAGCTGACGCTCACCACCGTGTTCCAGCCGATCTTCAGCCTCGCGCATCAGCGGGCAGTCG
GCTACGAAGCGCTTTTGCGCGCACACGACACGCTCGATCGCGCGGTGTCGCCGCTCGACGTGTTCGGCGATGCCGCGCGC
CACGGCGAACTGCTGCAGCTCGACCGGCTCGCGCAGGCGCTGCATCTCGAGAATTTCGCGCTGCTCGGCGCGTCGCGCGA
GTGGCTGTTTCTGAACGTGCACCCGGGCGTGCTCACCGATCCGTTCCAGGCGGCCGCGCTGCTCGCGAACCTGAAGCGGC
TCGGGATTCCACCGCGCCGCATCGTGCTCGAAGTGCTCGAACAGCGCGCGGACGACGTCGAGCGGCTCGCCGACGCGGTG
CGCGCATGCCGCGCGCAGGGCTTCCTGATCGCGCTCGACGATTTCGGCGCCGGGCACGCGAACGTCGAGCGGATCTGGCA
GCTCGATCCCGACATCGTGAAGCTCGACCGGATCCTGCTGTCGCAGGCCGCGCATCGCACGGGGCCGACCGCGATCCTGC
ACGGGCTCGTCGCGCTGCTGCACGAAGCGGGCAAGCTCGTGCTCGTCGAAGGGATCGAAACGGAGCACGACGCGCAGGTC
GCGCTCGCATGCGAAGCCGATTTCGTGCAGGGCTACTACTTCGGCCGGCCGGCGCCCGGCCTGCCCGACAGTGCCGCCGC
GACGGGCTGCATCGGCGAGCTGACCGAGCGCTTTCGCGAGCAGGCCGATGCGCGCGAGCGGCGCGACGCGCAGCGGCTCG
CGCCTTATCTGCGCGCGTTCGAGCGCGCCGCCGAACGCCTCGCGGCCGGCGAGCCGCTCGACGACGTGTGCTGGAACTTC
CTCGCGCTCGACGATGCGGCGCGCTGCTTCCTGCTCGACGCGCGCGGCCGGCAGGCCGGCCGCAACATCGTGCTGCGCGC
CGATCGCGCGCCGCGCGAGACGCGTTTTTCGCCGCTGTCCGAGGCGCAGGGTGCGAACTGGCTGCGGCGGCCGTATTTCC
GCACGGCGATCGCGGAGCCGGGGCGCGTTCAGGTGACGCGGCCGTACCTGTCGATCAACGAGGCGCAGCCGTGCGTGACG
CTGTCGATCGCGATCCGGATCGGCGATGCGCAGTGCGTGCTGTGCGGCGACATCGACTGGATCGACGGCTGA

Upstream 100 bases:

>100_bases
GCCGGATAAACCGAGGGTTCATCGACATGGGCCGATGCCGCGCGCCGTCCGGTTCGTCAGCCGCCGCGTTGCCGATGCAG
ACCGATTTCAGGAGGAACGC

Downstream 100 bases:

>100_bases
CGCGCAGGGTGGCGCACGGTACGCGGCTCGGCTAGGATGCGCGCATTGTCCCGACGAATCGCGCTGCCATGAACCGACCC
GCTGCTGCTGCCGTGCTCCT

Product: diguanylate phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 423; Mature: 422

Protein sequence:

>423_residues
MTTEQQERPVVASPYRFEREVSSGFERFATRHRELTLTTVFQPIFSLAHQRAVGYEALLRAHDTLDRAVSPLDVFGDAAR
HGELLQLDRLAQALHLENFALLGASREWLFLNVHPGVLTDPFQAAALLANLKRLGIPPRRIVLEVLEQRADDVERLADAV
RACRAQGFLIALDDFGAGHANVERIWQLDPDIVKLDRILLSQAAHRTGPTAILHGLVALLHEAGKLVLVEGIETEHDAQV
ALACEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFREQADARERRDAQRLAPYLRAFERAAERLAAGEPLDDVCWNF
LALDDAARCFLLDARGRQAGRNIVLRADRAPRETRFSPLSEAQGANWLRRPYFRTAIAEPGRVQVTRPYLSINEAQPCVT
LSIAIRIGDAQCVLCGDIDWIDG

Sequences:

>Translated_423_residues
MTTEQQERPVVASPYRFEREVSSGFERFATRHRELTLTTVFQPIFSLAHQRAVGYEALLRAHDTLDRAVSPLDVFGDAAR
HGELLQLDRLAQALHLENFALLGASREWLFLNVHPGVLTDPFQAAALLANLKRLGIPPRRIVLEVLEQRADDVERLADAV
RACRAQGFLIALDDFGAGHANVERIWQLDPDIVKLDRILLSQAAHRTGPTAILHGLVALLHEAGKLVLVEGIETEHDAQV
ALACEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFREQADARERRDAQRLAPYLRAFERAAERLAAGEPLDDVCWNF
LALDDAARCFLLDARGRQAGRNIVLRADRAPRETRFSPLSEAQGANWLRRPYFRTAIAEPGRVQVTRPYLSINEAQPCVT
LSIAIRIGDAQCVLCGDIDWIDG
>Mature_422_residues
TTEQQERPVVASPYRFEREVSSGFERFATRHRELTLTTVFQPIFSLAHQRAVGYEALLRAHDTLDRAVSPLDVFGDAARH
GELLQLDRLAQALHLENFALLGASREWLFLNVHPGVLTDPFQAAALLANLKRLGIPPRRIVLEVLEQRADDVERLADAVR
ACRAQGFLIALDDFGAGHANVERIWQLDPDIVKLDRILLSQAAHRTGPTAILHGLVALLHEAGKLVLVEGIETEHDAQVA
LACEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFREQADARERRDAQRLAPYLRAFERAAERLAAGEPLDDVCWNFL
ALDDAARCFLLDARGRQAGRNIVLRADRAPRETRFSPLSEAQGANWLRRPYFRTAIAEPGRVQVTRPYLSINEAQPCVTL
SIAIRIGDAQCVLCGDIDWIDG

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG2200

COG function: function code T; FOG: EAL domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=230, Percent_Identity=24.7826086956522, Blast_Score=82, Evalue=5e-17,
Organism=Escherichia coli, GI87082096, Length=150, Percent_Identity=30, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI87081980, Length=264, Percent_Identity=25.3787878787879, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1787055, Length=235, Percent_Identity=26.3829787234043, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081921, Length=235, Percent_Identity=24.6808510638298, Blast_Score=68, Evalue=1e-12,
Organism=Escherichia coli, GI87081743, Length=247, Percent_Identity=26.7206477732794, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786507, Length=226, Percent_Identity=26.1061946902655, Blast_Score=66, Evalue=4e-12,
Organism=Escherichia coli, GI1787410, Length=229, Percent_Identity=23.5807860262009, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788502, Length=230, Percent_Identity=24.7826086956522, Blast_Score=65, Evalue=1e-11,
Organism=Escherichia coli, GI1788849, Length=215, Percent_Identity=26.5116279069767, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI226510982, Length=155, Percent_Identity=28.3870967741935, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 47013; Mature: 46882

Theoretical pI: Translated: 5.82; Mature: 5.82

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
0.2 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTEQQERPVVASPYRFEREVSSGFERFATRHRELTLTTVFQPIFSLAHQRAVGYEALLR
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHDTLDRAVSPLDVFGDAARHGELLQLDRLAQALHLENFALLGASREWLFLNVHPGVLTD
HHHHHHHHCCCHHHHCCHHHCCCHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCC
PFQAAALLANLKRLGIPPRRIVLEVLEQRADDVERLADAVRACRAQGFLIALDDFGAGHA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
NVERIWQLDPDIVKLDRILLSQAAHRTGPTAILHGLVALLHEAGKLVLVEGIETEHDAQV
CHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEE
ALACEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFREQADARERRDAQRLAPYLRAF
EEEECHHHHHCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAAERLAAGEPLDDVCWNFLALDDAARCFLLDARGRQAGRNIVLRADRAPRETRFSPLS
HHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCH
EAQGANWLRRPYFRTAIAEPGRVQVTRPYLSINEAQPCVTLSIAIRIGDAQCVLCGDIDW
HHCCCCHHHHHHHHHHHCCCCCEEEECCCEECCCCCCEEEEEEEEEECCCEEEEECCCCC
IDG
CCC
>Mature Secondary Structure 
TTEQQERPVVASPYRFEREVSSGFERFATRHRELTLTTVFQPIFSLAHQRAVGYEALLR
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AHDTLDRAVSPLDVFGDAARHGELLQLDRLAQALHLENFALLGASREWLFLNVHPGVLTD
HHHHHHHHCCCHHHHCCHHHCCCHHHHHHHHHHHHHHHHHEECCCCCEEEEEECCCCCCC
PFQAAALLANLKRLGIPPRRIVLEVLEQRADDVERLADAVRACRAQGFLIALDDFGAGHA
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCCCC
NVERIWQLDPDIVKLDRILLSQAAHRTGPTAILHGLVALLHEAGKLVLVEGIETEHDAQV
CHHHHHCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCEEEEECCCCCCCCEE
ALACEADFVQGYYFGRPAPGLPDSAAATGCIGELTERFREQADARERRDAQRLAPYLRAF
EEEECHHHHHCEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ERAAERLAAGEPLDDVCWNFLALDDAARCFLLDARGRQAGRNIVLRADRAPRETRFSPLS
HHHHHHHHCCCCHHHHHHHHHHHCCCCEEEEEECCCCCCCCEEEEECCCCCCCCCCCCCH
EAQGANWLRRPYFRTAIAEPGRVQVTRPYLSINEAQPCVTLSIAIRIGDAQCVLCGDIDW
HHCCCCHHHHHHHHHHHCCCCCEEEECCCEECCCCCCEEEEEEEEEECCCEEEEECCCCC
IDG
CCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]