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The map label for this gene is hitA [H]

Identifier: 161523518

GI number: 161523518

Start: 366995

End: 367360

Strand: Direct

Name: hitA [H]

Synonym: Bmul_0338

Alternate gene names: 161523518

Gene position: 366995-367360 (Clockwise)

Preceding gene: 161523517

Following gene: 161523519

Centisome position: 10.64

GC content: 67.49

Gene sequence:

>366_bases
ATGAGTCACGATCCGAATTGCCTGTTCTGCAAGATCGCGGCAGGCGAAATCCCGAGCACGAAAGTGCACGAGGACGACGA
ATTCGTCGCATTCCGCGACATCCGCCCGGCGGCCGACACGCACGTGCTCGTGATCCCGCGTCGCCATCTGCCGACGCTGT
CGGCGGCGACCGACGACGACGCGCCGATGCTCGGCCGGCTGATGGTGCTCGTCGCGCGGCTTGCCGATCAGCTGGGCGTC
GCGTATACGGGCGGCGAAACGGGTTTCCGCACCGTGATCAACACGGGCCCCGGCGGCGGGCAGGAGGTTTACCATCTGCA
CGCGCACATCCTGGCCGGCCCGCGTCCGTGGCAGCGGATGGGTTGA

Upstream 100 bases:

>100_bases
TACCGTATCATCAAGGGTTGGCTGTACCTGAACGACAACAAGGCGCTCGATCCGCAGGCCTGGTTCTGACGGGCCGCGTG
CGGGCACCAGCAGGAGCAAC

Downstream 100 bases:

>100_bases
CGGCGCGGGCATTTTCCGCATTGACAGTCGAAGCCGGCGCGTCGCCGGCGATTTGCGCCGCACGCGGCGTAGTTGAGGAG
AGGTTTCATCATGGGTGGAT

Product: histidine triad (HIT) protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 121; Mature: 120

Protein sequence:

>121_residues
MSHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRRHLPTLSAATDDDAPMLGRLMVLVARLADQLGV
AYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRMG

Sequences:

>Translated_121_residues
MSHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRRHLPTLSAATDDDAPMLGRLMVLVARLADQLGV
AYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRMG
>Mature_120_residues
SHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRRHLPTLSAATDDDAPMLGRLMVLVARLADQLGVA
YTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRMG

Specific function: Unknown

COG id: COG0537

COG function: function code FGR; Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HIT domain [H]

Homologues:

Organism=Homo sapiens, GI4885413, Length=108, Percent_Identity=45.3703703703704, Blast_Score=100, Evalue=2e-22,
Organism=Homo sapiens, GI14211923, Length=107, Percent_Identity=37.3831775700935, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1787346, Length=112, Percent_Identity=44.6428571428571, Blast_Score=86, Evalue=5e-19,
Organism=Caenorhabditis elegans, GI17506713, Length=108, Percent_Identity=46.2962962962963, Blast_Score=104, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6320078, Length=108, Percent_Identity=35.1851851851852, Blast_Score=64, Evalue=8e-12,
Organism=Drosophila melanogaster, GI28574010, Length=108, Percent_Identity=49.0740740740741, Blast_Score=101, Evalue=1e-22,
Organism=Drosophila melanogaster, GI24581222, Length=108, Percent_Identity=49.0740740740741, Blast_Score=101, Evalue=1e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011146
- InterPro:   IPR011151
- InterPro:   IPR019808
- InterPro:   IPR001310 [H]

Pfam domain/function: NA

EC number: NA

Molecular weight: Translated: 13135; Mature: 13004

Theoretical pI: Translated: 6.62; Mature: 6.62

Prosite motif: PS51084 HIT_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRRHLPTLSAATDDD
CCCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCC
APMLGRLMVLVARLADQLGVAYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRM
CHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCCC
G
C
>Mature Secondary Structure 
SHDPNCLFCKIAAGEIPSTKVHEDDEFVAFRDIRPAADTHVLVIPRRHLPTLSAATDDD
CCCCCEEEEEEECCCCCCCCCCCCCCEEEEECCCCCCCCEEEEEECCCCCCCCCCCCCC
APMLGRLMVLVARLADQLGVAYTGGETGFRTVINTGPGGGQEVYHLHAHILAGPRPWQRM
CHHHHHHHHHHHHHHHHCCEEEECCCCCEEEEEECCCCCCCEEEEEEEEEECCCCCCCCC
G
C

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA