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The map label for this gene is mlaA [H]

Identifier: 161523500

GI number: 161523500

Start: 353171

End: 354148

Strand: Direct

Name: mlaA [H]

Synonym: Bmul_0320

Alternate gene names: 161523500

Gene position: 353171-354148 (Clockwise)

Preceding gene: 161523499

Following gene: 161523501

Centisome position: 10.24

GC content: 71.17

Gene sequence:

>978_bases
ATGCAGACGATCCGGATCAGGCACGCCGCGCTCGCGGCTGCGGCGGTCGCCGCGTTGAGCGGCTGCGCGACCGTGCAGAC
GCCGACCAAGGGCGATCCGCTCGAAGGCTTCAACCGCACGATGTACAAGTTCAACGACACCGTCGACACGTACGCGCTGA
AGCCGGTCGCGAAGGGCTATCAGTACGTGGTGCCGCAGCCGGTGCGCGACAGCGTGACGAACTTCTTCTCGAACATCGGC
GACGTCTATATTGCGGCGAACAACCTCGTGCAGCTGCGCATCGCGGACGGCGTCGGCGACCTGATGCGTGTCGTGATCAA
CACGGTATTCGGCGTCGGCGGCCTGTTCGACGTCGCGACGATCGCGAAGCTGCCGAAGCACACGGCCGATTTCGGGATCA
CGATGGGCCGCTACGGCGTGCCGTCGGGCCCGTACCTCGTGCTGCCGCTGCTCGGCCCGAGCACGCTGCGCGATGCGGCC
GGCCTCGGCGTCGACTACGTCGGCAATCCGCTCACCTACGTGAAGCCGGACAGCGTGAGCTGGGGGCTGTACGGCGTGAA
CCTCGTCAACACGCGCGCGAACCTGCTCGGCGCGGGCGACGTGCTCGATGCCGCGGCGCTCGACAAGTATTCGTTCGTGC
GTAACGCCTATCTGCAGCGCCGCCAGATGCTGATCAACAACGCACGCGGCGAGGCCGGCGCGCCGGCGTCGAACGACGCG
CTGCCGCAGTACGAGCTGCCGGAAGACACGGCGGCGCCGGCGGCAGCCGGCGCTGCAGGCAGCGCGGGTGCTGCGGCGGC
GGGCAGCGCCGGTGCCGCGGCGGTCGGCGGCGCAGCCGCGCCCGCGGGCGCATCGGCTGCCGAGCCGGCCTCCGGCGCAG
CCGCGCCGAACCCCGCGAGCGCAACGACGGTGCCGCCGATGCAGGTGACGCCGCCGGCGCCGGGCGGCCTGCGCCTGCCG
AGCTTCCGGCTGCACTGA

Upstream 100 bases:

>100_bases
CGGCGCGCCGGCCGCACCGGCTCCCGTGCCGGTGCCGGCATCGGCGGTCGCGGGTTCGGCCGCACAATAAACACACAAGA
GAACAAAGAGGGTAACCAAC

Downstream 100 bases:

>100_bases
CCGGCTTACATTCGTTACAGCCGGAAACGATTCAATCGGTAGCGCACGCGAACTTGCGCGTAAGCTACCGGCTCCAACCT
TCGCATCGACTCATTCATGC

Product: VacJ family lipoprotein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 325; Mature: 325

Protein sequence:

>325_residues
MQTIRIRHAALAAAAVAALSGCATVQTPTKGDPLEGFNRTMYKFNDTVDTYALKPVAKGYQYVVPQPVRDSVTNFFSNIG
DVYIAANNLVQLRIADGVGDLMRVVINTVFGVGGLFDVATIAKLPKHTADFGITMGRYGVPSGPYLVLPLLGPSTLRDAA
GLGVDYVGNPLTYVKPDSVSWGLYGVNLVNTRANLLGAGDVLDAAALDKYSFVRNAYLQRRQMLINNARGEAGAPASNDA
LPQYELPEDTAAPAAAGAAGSAGAAAAGSAGAAAVGGAAAPAGASAAEPASGAAAPNPASATTVPPMQVTPPAPGGLRLP
SFRLH

Sequences:

>Translated_325_residues
MQTIRIRHAALAAAAVAALSGCATVQTPTKGDPLEGFNRTMYKFNDTVDTYALKPVAKGYQYVVPQPVRDSVTNFFSNIG
DVYIAANNLVQLRIADGVGDLMRVVINTVFGVGGLFDVATIAKLPKHTADFGITMGRYGVPSGPYLVLPLLGPSTLRDAA
GLGVDYVGNPLTYVKPDSVSWGLYGVNLVNTRANLLGAGDVLDAAALDKYSFVRNAYLQRRQMLINNARGEAGAPASNDA
LPQYELPEDTAAPAAAGAAGSAGAAAAGSAGAAAVGGAAAPAGASAAEPASGAAAPNPASATTVPPMQVTPPAPGGLRLP
SFRLH
>Mature_325_residues
MQTIRIRHAALAAAAVAALSGCATVQTPTKGDPLEGFNRTMYKFNDTVDTYALKPVAKGYQYVVPQPVRDSVTNFFSNIG
DVYIAANNLVQLRIADGVGDLMRVVINTVFGVGGLFDVATIAKLPKHTADFGITMGRYGVPSGPYLVLPLLGPSTLRDAA
GLGVDYVGNPLTYVKPDSVSWGLYGVNLVNTRANLLGAGDVLDAAALDKYSFVRNAYLQRRQMLINNARGEAGAPASNDA
LPQYELPEDTAAPAAAGAAGSAGAAAAGSAGAAAVGGAAAPAGASAAEPASGAAAPNPASATTVPPMQVTPPAPGGLRLP
SFRLH

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane [H]

COG id: COG2853

COG function: function code M; Surface lipoprotein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaA family [H]

Homologues:

Organism=Escherichia coli, GI1788688, Length=231, Percent_Identity=39.8268398268398, Blast_Score=136, Evalue=2e-33,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007428 [H]

Pfam domain/function: PF04333 VacJ [H]

EC number: NA

Molecular weight: Translated: 33090; Mature: 33090

Theoretical pI: Translated: 8.36; Mature: 8.36

Prosite motif: PS00013 PROKAR_LIPOPROTEIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQTIRIRHAALAAAAVAALSGCATVQTPTKGDPLEGFNRTMYKFNDTVDTYALKPVAKGY
CCEEEHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHEEECCCHHHHHHHHHHCCC
QYVVPQPVRDSVTNFFSNIGDVYIAANNLVQLRIADGVGDLMRVVINTVFGVGGLFDVAT
EEECCCCHHHHHHHHHHHCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
IAKLPKHTADFGITMGRYGVPSGPYLVLPLLGPSTLRDAAGLGVDYVGNPLTYVKPDSVS
HHHCCCCHHHHCEECCCCCCCCCCEEEEECCCCHHHHHHHCCCCHHCCCCEEEECCCCCC
WGLYGVNLVNTRANLLGAGDVLDAAALDKYSFVRNAYLQRRQMLINNARGEAGAPASNDA
CCEEEEEEECCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LPQYELPEDTAAPAAAGAAGSAGAAAAGSAGAAAVGGAAAPAGASAAEPASGAAAPNPAS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
ATTVPPMQVTPPAPGGLRLPSFRLH
CCCCCCEEECCCCCCCCCCCCCCCC
>Mature Secondary Structure
MQTIRIRHAALAAAAVAALSGCATVQTPTKGDPLEGFNRTMYKFNDTVDTYALKPVAKGY
CCEEEHHHHHHHHHHHHHHHCCCEECCCCCCCCCCCCCCHHEEECCCHHHHHHHHHHCCC
QYVVPQPVRDSVTNFFSNIGDVYIAANNLVQLRIADGVGDLMRVVINTVFGVGGLFDVAT
EEECCCCHHHHHHHHHHHCCCEEEEECCEEEEEECCCHHHHHHHHHHHHHCCCHHHHHHH
IAKLPKHTADFGITMGRYGVPSGPYLVLPLLGPSTLRDAAGLGVDYVGNPLTYVKPDSVS
HHHCCCCHHHHCEECCCCCCCCCCEEEEECCCCHHHHHHHCCCCHHCCCCEEEECCCCCC
WGLYGVNLVNTRANLLGAGDVLDAAALDKYSFVRNAYLQRRQMLINNARGEAGAPASNDA
CCEEEEEEECCHHHHEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCC
LPQYELPEDTAAPAAAGAAGSAGAAAAGSAGAAAVGGAAAPAGASAAEPASGAAAPNPAS
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHCCCCCCCCCCCCCCCCCCCCCCCCCC
ATTVPPMQVTPPAPGGLRLPSFRLH
CCCCCCEEECCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 9205837; 9278503 [H]