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The map label for this gene is fusA1 [H]

Identifier: 161523426

GI number: 161523426

Start: 284975

End: 287077

Strand: Direct

Name: fusA1 [H]

Synonym: Bmul_0246

Alternate gene names: 161523426

Gene position: 284975-287077 (Clockwise)

Preceding gene: 161523425

Following gene: 161523427

Centisome position: 8.26

GC content: 61.91

Gene sequence:

>2103_bases
GTGGCTCGCAAGACTCCCATCGAGCGCTACCGCAATATCGGTATTAGCGCTCACATCGACGCCGGCAAGACGACGACGAC
CGAGCGCATTCTGTTTTACACCGGTGTGAACCACAAGATCGGTGAAGTCCACGACGGCGCAGCAACGATGGACTGGATGG
AGCAGGAACAGGAGCGTGGCATCACGATCACGTCCGCTGCTACCACCGCCTTCTGGAAGGGCATGGGCGGCAACTATCCG
GAACACCGCATCAACATCATCGACACGCCGGGGCACGTCGACTTCACGATCGAAGTGGAGCGTTCGATGCGCGTGCTGGA
CGGCGCGTGCATGGTTTACTGCGCAGTGGGCGGCGTACAGCCGCAGTCGGAAACGGTGTGGCGCCAGGCGAACAAGTACA
AGGTGCCGCGTCTCGCGTTCGTCAACAAGATGGACCGTACCGGCGCGAACTTCTTCAAGGTCTACGACCAGCTCCGTCTG
CGCCTGAAGGCGAACCCGGTTCCGGTCGTGGTGCCGATCGGCGCGGAAGAAAACTTCAAGGGCGTCGTCGATCTGCTGAA
GATGAAGGCGATCATTTGGGACGAGGCGTCGCAGGGCACGAAGTTCGACTACGTCGACATCCCGGCCGAGCTGGTCGATA
CGTGCCAGGAATGGCGTGAAAAGATGGTCGAGGCGGCTGCGGAAGCCAACGAAGACCTGATGAACAAGTACCTGGAAGAA
GGCGATCTGCCGGAAGCCGACATCATCAAGGCGCTGCGCGACCGTACGATCGCGTGCGAAATCCAGCCGATGCTGTGCGG
TACCGCGTTCAAGAACAAGGGCGTGCAGCGCATGCTCGACGCCGTGATCGACTTCCTGCCGTCGCCGGTCGACATCCCGC
CGGTCAAGGGCGAGCTCGACAACGGCGAAACGGCCGAGCGCAAGGCGTCGGACGACGAGAAGTTCTCGTCGCTCGCGTTC
AAGATCATGACCGACCCGTTCGTCGGCCAGCTGATCTTCTTCCGCGTGTACTCGGGCGTCGTCAACTCGGGCGACACGGT
GCTGAACTCGACCAAGGGCAAGAAGGAACGCCTCGGCCGTATTCTGCAGATGCACGCGAACAACCGTGAGGAAATCAAGG
AAGTTCGCGCGGGCGACATCGCCGCTGCGGTCGGCCTGAAGGAAGCGACCACGGGCGACACGCTGTGCGATCCGGCCAAC
CCGATCGTGCTCGAGCGCATGGTGTTCCCGGAGCCGGTGATTTCGCAGGCTGTCGAGCCGAAGACGAAGGCCGACCAGGA
AAAGATGGGCCTCGCGCTGAACCGTCTCGCGCAGGAAGATCCGTCGTTCCGCGTGCAGACCGACGAAGAGTCGGGCCAGA
CCATCATTTCGGGCATGGGCGAGCTCCACCTCGAAATTCTGGTCGACCGGATGAAGCGTGAATTCGGCGTCGAAGCAACG
GTCGGCAAGCCGCAGGTTGCGTACCGCGAAACGATCCGTTCGACGGCGAAGGACGTCGAAGGCAAGTTCGTCAAGCAGTC
GGGCGGCCGCGGCCAGTACGGTCACGCAGTCATCACGCTCGAGCCGAACGAACAGGGCAAGGGCTACGAGTTCTTCGACG
AGATCAAGGGCGGCGTGATTCCGCGCGAATACATCCCGGCGGTCGACAAGGGTATCCAGGACACGCTGAAGTCGGGCGTG
CTGGCCGGCTTCCCGGTCGTCGACGTGAAGGTTCACCTGACGTTCGGTTCGTACCACGACGTCGACTCGAACGAAAACGC
GTTCCGCATGGCCGGTTCGATGGCGTTCAAGGAAGCGATGCGCAAGGCGAATCCGGTGGTGCTCGAGCCGATGATGGCTG
TCGAGGTCGAGACGCCGGAAGAGTACATGGGCAACGTGATGGGCGACCTGTCGGGCCGTCGCGGCATCGTTCAGGGCATG
GAAGACATGGTCGGCGGCGGCAAGATCGTTCGCGCCGAAGTGCCGCTGTCGGAAATGTTCGGTTACTCGACCTCGCTGCG
CTCGCTGACGCAAGGCCGTGCAACGTACACGATGGAGTTCAAGCACTACGCTGAAGCTCCGCGCAACGTTGCCGACGCGA
TCATCAGCGCGAAGTCGAAGTAA

Upstream 100 bases:

>100_bases
AAATAAATTCCGGGCGGGTGCGCTTTTCGAGCGCCTCGCCCGTTTGTGTTGAGGCGCGATGCAGCAGGGCTGCGTCGCGC
CATCCCAGTAGAGGATCAAA

Downstream 100 bases:

>100_bases
ATCTGCATCTACCAACTGATTATTTTTTGAAAGAAGAGAATCATGGCAAAAGAGAAGTTTGAGCGGACCAAGCCGCACGT
GAACGTTGGTACGATTGGTC

Product: elongation factor G

Products: NA

Alternate protein names: EF-G 1 [H]

Number of amino acids: Translated: 700; Mature: 699

Protein sequence:

>700_residues
MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWKGMGGNYP
EHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLRL
RLKANPVPVVVPIGAEENFKGVVDLLKMKAIIWDEASQGTKFDYVDIPAELVDTCQEWREKMVEAAAEANEDLMNKYLEE
GDLPEADIIKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVKGELDNGETAERKASDDEKFSSLAF
KIMTDPFVGQLIFFRVYSGVVNSGDTVLNSTKGKKERLGRILQMHANNREEIKEVRAGDIAAAVGLKEATTGDTLCDPAN
PIVLERMVFPEPVISQAVEPKTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEAT
VGKPQVAYRETIRSTAKDVEGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFFDEIKGGVIPREYIPAVDKGIQDTLKSGV
LAGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAMRKANPVVLEPMMAVEVETPEEYMGNVMGDLSGRRGIVQGM
EDMVGGGKIVRAEVPLSEMFGYSTSLRSLTQGRATYTMEFKHYAEAPRNVADAIISAKSK

Sequences:

>Translated_700_residues
MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWKGMGGNYP
EHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLRL
RLKANPVPVVVPIGAEENFKGVVDLLKMKAIIWDEASQGTKFDYVDIPAELVDTCQEWREKMVEAAAEANEDLMNKYLEE
GDLPEADIIKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVKGELDNGETAERKASDDEKFSSLAF
KIMTDPFVGQLIFFRVYSGVVNSGDTVLNSTKGKKERLGRILQMHANNREEIKEVRAGDIAAAVGLKEATTGDTLCDPAN
PIVLERMVFPEPVISQAVEPKTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEAT
VGKPQVAYRETIRSTAKDVEGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFFDEIKGGVIPREYIPAVDKGIQDTLKSGV
LAGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAMRKANPVVLEPMMAVEVETPEEYMGNVMGDLSGRRGIVQGM
EDMVGGGKIVRAEVPLSEMFGYSTSLRSLTQGRATYTMEFKHYAEAPRNVADAIISAKSK
>Mature_699_residues
ARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERGITITSAATTAFWKGMGGNYPE
HRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQPQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLRLR
LKANPVPVVVPIGAEENFKGVVDLLKMKAIIWDEASQGTKFDYVDIPAELVDTCQEWREKMVEAAAEANEDLMNKYLEEG
DLPEADIIKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVKGELDNGETAERKASDDEKFSSLAFK
IMTDPFVGQLIFFRVYSGVVNSGDTVLNSTKGKKERLGRILQMHANNREEIKEVRAGDIAAAVGLKEATTGDTLCDPANP
IVLERMVFPEPVISQAVEPKTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEATV
GKPQVAYRETIRSTAKDVEGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFFDEIKGGVIPREYIPAVDKGIQDTLKSGVL
AGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAMRKANPVVLEPMMAVEVETPEEYMGNVMGDLSGRRGIVQGME
DMVGGGKIVRAEVPLSEMFGYSTSLRSLTQGRATYTMEFKHYAEAPRNVADAIISAKSK

Specific function: Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post- translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and

COG id: COG0480

COG function: function code J; Translation elongation factors (GTPases)

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GTP-binding elongation factor family. EF-G/EF-2 subfamily [H]

Homologues:

Organism=Homo sapiens, GI18390331, Length=692, Percent_Identity=45.5202312138728, Blast_Score=557, Evalue=1e-158,
Organism=Homo sapiens, GI19923640, Length=718, Percent_Identity=38.7186629526462, Blast_Score=459, Evalue=1e-129,
Organism=Homo sapiens, GI25306287, Length=718, Percent_Identity=36.7688022284123, Blast_Score=415, Evalue=1e-116,
Organism=Homo sapiens, GI25306283, Length=456, Percent_Identity=40.7894736842105, Blast_Score=307, Evalue=2e-83,
Organism=Homo sapiens, GI4503483, Length=495, Percent_Identity=28.0808080808081, Blast_Score=115, Evalue=2e-25,
Organism=Homo sapiens, GI157426893, Length=153, Percent_Identity=34.640522875817, Blast_Score=99, Evalue=2e-20,
Organism=Homo sapiens, GI94966754, Length=136, Percent_Identity=40.4411764705882, Blast_Score=93, Evalue=7e-19,
Organism=Homo sapiens, GI310132016, Length=120, Percent_Identity=40.8333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI310110807, Length=120, Percent_Identity=40.8333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI310123363, Length=120, Percent_Identity=40.8333333333333, Blast_Score=79, Evalue=1e-14,
Organism=Escherichia coli, GI1789738, Length=705, Percent_Identity=74.7517730496454, Blast_Score=1073, Evalue=0.0,
Organism=Escherichia coli, GI1790835, Length=493, Percent_Identity=27.5862068965517, Blast_Score=160, Evalue=2e-40,
Organism=Escherichia coli, GI48994988, Length=182, Percent_Identity=37.3626373626374, Blast_Score=106, Evalue=5e-24,
Organism=Escherichia coli, GI1788922, Length=148, Percent_Identity=35.8108108108108, Blast_Score=88, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17533571, Length=691, Percent_Identity=42.8364688856729, Blast_Score=516, Evalue=1e-146,
Organism=Caenorhabditis elegans, GI17556745, Length=721, Percent_Identity=30.7905686546463, Blast_Score=313, Evalue=2e-85,
Organism=Caenorhabditis elegans, GI17506493, Length=490, Percent_Identity=28.3673469387755, Blast_Score=119, Evalue=6e-27,
Organism=Caenorhabditis elegans, GI17557151, Length=163, Percent_Identity=38.0368098159509, Blast_Score=94, Evalue=2e-19,
Organism=Caenorhabditis elegans, GI71988819, Length=146, Percent_Identity=32.1917808219178, Blast_Score=75, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI71988811, Length=146, Percent_Identity=32.1917808219178, Blast_Score=74, Evalue=3e-13,
Organism=Saccharomyces cerevisiae, GI6323098, Length=694, Percent_Identity=42.7953890489914, Blast_Score=545, Evalue=1e-156,
Organism=Saccharomyces cerevisiae, GI6322359, Length=793, Percent_Identity=32.6607818411097, Blast_Score=386, Evalue=1e-108,
Organism=Saccharomyces cerevisiae, GI6324707, Length=422, Percent_Identity=27.9620853080569, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6320593, Length=422, Percent_Identity=27.9620853080569, Blast_Score=105, Evalue=2e-23,
Organism=Saccharomyces cerevisiae, GI6323320, Length=157, Percent_Identity=36.3057324840764, Blast_Score=96, Evalue=2e-20,
Organism=Saccharomyces cerevisiae, GI6324166, Length=144, Percent_Identity=37.5, Blast_Score=83, Evalue=1e-16,
Organism=Drosophila melanogaster, GI24582462, Length=711, Percent_Identity=44.7257383966245, Blast_Score=579, Evalue=1e-165,
Organism=Drosophila melanogaster, GI221458488, Length=723, Percent_Identity=32.088520055325, Blast_Score=353, Evalue=2e-97,
Organism=Drosophila melanogaster, GI24585711, Length=491, Percent_Identity=26.8839103869654, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24585713, Length=491, Percent_Identity=26.8839103869654, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24585709, Length=491, Percent_Identity=26.8839103869654, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI78706572, Length=161, Percent_Identity=36.6459627329193, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI28574573, Length=143, Percent_Identity=38.4615384615385, Blast_Score=90, Evalue=4e-18,

Paralogues:

None

Copy number: 1080 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 2520 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). 20 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). 7984 Molecules/Cell In: Growth Phase, Gl

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR000795
- InterPro:   IPR020568
- InterPro:   IPR014721
- InterPro:   IPR005225
- InterPro:   IPR004540
- InterPro:   IPR000640
- InterPro:   IPR005517
- InterPro:   IPR004161
- InterPro:   IPR009000 [H]

Pfam domain/function: PF00679 EFG_C; PF03764 EFG_IV; PF00009 GTP_EFTU; PF03144 GTP_EFTU_D2 [H]

EC number: NA

Molecular weight: Translated: 77493; Mature: 77362

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: PS00301 EFACTOR_GTP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.1 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERG
CCCCCHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
ITITSAATTAFWKGMGGNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQ
EEEEEHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECHHHHHHHHHHEEHEECCCCC
PQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLRLRLKANPVPVVVPIGAEENFK
CCHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHEECCCCEEEEECCCCCCHH
GVVDLLKMKAIIWDEASQGTKFDYVDIPAELVDTCQEWREKMVEAAAEANEDLMNKYLEE
HHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GDLPEADIIKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVKGELD
CCCCHHHHHHHHHCCEEEEEEEHHHHCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
NGETAERKASDDEKFSSLAFKIMTDPFVGQLIFFRVYSGVVNSGDTVLNSTKGKKERLGR
CCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHH
ILQMHANNREEIKEVRAGDIAAAVGLKEATTGDTLCDPANPIVLERMVFPEPVISQAVEP
HHHHHCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCC
KTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEAT
CCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEC
VGKPQVAYRETIRSTAKDVEGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFFDEIKGGVI
CCCCHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCC
PREYIPAVDKGIQDTLKSGVLAGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAM
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RKANPVVLEPMMAVEVETPEEYMGNVMGDLSGRRGIVQGMEDMVGGGKIVRAEVPLSEMF
HHCCCEEECCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCHHHHH
GYSTSLRSLTQGRATYTMEFKHYAEAPRNVADAIISAKSK
CCHHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHCCCC
>Mature Secondary Structure 
ARKTPIERYRNIGISAHIDAGKTTTTERILFYTGVNHKIGEVHDGAATMDWMEQEQERG
CCCCHHHHHHCCCCEEEECCCCCCCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHCC
ITITSAATTAFWKGMGGNYPEHRINIIDTPGHVDFTIEVERSMRVLDGACMVYCAVGGVQ
EEEEEHHHHHHHHCCCCCCCCCEEEEEECCCCEEEEEEECHHHHHHHHHHEEHEECCCCC
PQSETVWRQANKYKVPRLAFVNKMDRTGANFFKVYDQLRLRLKANPVPVVVPIGAEENFK
CCHHHHHHHHCCCCCCHHHHHHHHCCCCHHHHHHHHHHHHHEECCCCEEEEECCCCCCHH
GVVDLLKMKAIIWDEASQGTKFDYVDIPAELVDTCQEWREKMVEAAAEANEDLMNKYLEE
HHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHC
GDLPEADIIKALRDRTIACEIQPMLCGTAFKNKGVQRMLDAVIDFLPSPVDIPPVKGELD
CCCCHHHHHHHHHCCEEEEEEEHHHHCHHHHCCCHHHHHHHHHHHCCCCCCCCCCCCCCC
NGETAERKASDDEKFSSLAFKIMTDPFVGQLIFFRVYSGVVNSGDTVLNSTKGKKERLGR
CCCCHHHCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHCCCCHHHCCCCCHHHHHHH
ILQMHANNREEIKEVRAGDIAAAVGLKEATTGDTLCDPANPIVLERMVFPEPVISQAVEP
HHHHHCCCHHHHHHHHHCCHHHHHCCCCCCCCCCCCCCCCCHHHHHHCCCCHHHHHHCCC
KTKADQEKMGLALNRLAQEDPSFRVQTDEESGQTIISGMGELHLEILVDRMKREFGVEAT
CCCCCHHHHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCEEC
VGKPQVAYRETIRSTAKDVEGKFVKQSGGRGQYGHAVITLEPNEQGKGYEFFDEIKGGVI
CCCCHHHHHHHHHHHHHHHCCHHEECCCCCCCCCCEEEEECCCCCCCCCHHHHHHCCCCC
PREYIPAVDKGIQDTLKSGVLAGFPVVDVKVHLTFGSYHDVDSNENAFRMAGSMAFKEAM
CHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
RKANPVVLEPMMAVEVETPEEYMGNVMGDLSGRRGIVQGMEDMVGGGKIVRAEVPLSEMF
HHCCCEEECCEEEEEECCCHHHHHHHHHHCCCCCHHHHHHHHHCCCCEEEEEECCHHHHH
GYSTSLRSLTQGRATYTMEFKHYAEAPRNVADAIISAKSK
CCHHHHHHHHCCCCEEEEEHHHHHHCCHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA