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The map label for this gene is recQ [H]

Identifier: 161523423

GI number: 161523423

Start: 281753

End: 283600

Strand: Direct

Name: recQ [H]

Synonym: Bmul_0243

Alternate gene names: 161523423

Gene position: 281753-283600 (Clockwise)

Preceding gene: 161523422

Following gene: 161523424

Centisome position: 8.17

GC content: 67.86

Gene sequence:

>1848_bases
ATGTCTCGCGCCCTCGAAATCCTCGACGAAGTCTTCGGTTATTCCGCCTTCCGCGGCCAGCAGGGCGAGATCGTCGAGCA
CGTCGCGAGCGGCGGCGACTGTCTGGTGCTGATGCCAACGGGCGGCGGCAAGTCGCTGTGCTACCAGATTCCCGCGCTGA
TGCGCCGCGAGGCCGGCCATGGCGCGGGCATCGTCGTGTCGCCGCTGATCGCGCTGATGCAGGATCAGGTCGCCGCGCTG
CGCGAAGTCGGCGTGCGCGCCGCGTACCTGAACTCGACGCTGTCGGGCGCCGAGGCCGCGGCGACCGAGCGCGCGCTGCG
CGAAGGCGAGATCGATCTGCTGTATGTCGCGCCCGAACGGCTGATGACGGGGCGTTTTCTCGAGCTGCTCGAACGCGCGA
AGATCGGGCTGTTCGCGATCGACGAGGCGCACTGCGTGTCGCAGTGGGGGCACGACTTCCGCCCGGAATACATCCAGCTG
TCGGTGCTGCACGAGCGGTTCCCGACCGTGCCGCGCATCGCGCTGACGGCGACTGCCGATGCGATCACGCGCGACGAAAT
CATTCACCGTCTCGCGCTCGACGACGCGCGCGTATTCGTGTCGAGCTTCGATCGGCCGAACATCCGCTATCGGATCGTCG
AGAAGGACAACGCGCGCGCGCAGCTGCTCGATTTCATCCGCGCCGAACACACGAATGCCGACGGCACGACCGACGCCGGC
GTCGTCTATTGCCTGTCGCGCCGCAAGGTCGAGGAAACGGCCGAGTGGCTGAAGGCGCAGGGCATCCGCGCGCTGCCTTA
TCACGCCGGCATGGACTTCGAAGTGCGGCAGAAGCATCAGGAGATGTTCCAGCGCGAGGAAGGCATCGTGATGTGCGCGA
CGATCGCGTTCGGGATGGGCATCGACAAGCCCGACGTGCGCTTCGTCGCGCACCTCGATCTGCCGAAGAGCGTCGAAGGC
TATTACCAGGAGACAGGGCGCGCAGGGCGCGACGGGCTGCCGGCGAACGCGTGGATGGCGTACGGGCTCGGCGACGTCGT
CCAGCAGCGCAAGATGATCGACGAGTCCGATGCCGACGACGCGCACAAGCGCGTGCAGACCTCGAAGCTCGACGCGCTGC
TCGGCCTGTGCGAGACGATCTCGTGTCGCCGCGTGCGGCTGCTCAACTATTTCGGCGAGGCGAGCCAGCCCTGCGGAAAC
TGCGATACGTGCCTCGAGCCGCCCGCATCGTGGGACGCGACGCGCGAAGCGCAAATGGCGCTGTCGTGCGTGTTCCGCGC
GCAGCGCGCAAGCGGCTTCAACTTCGGCGCGAGCCACCTGATCGAGATCCTGCGCGGCGCGCGTACCGAAAAGGTGCTGC
AGCGCGGGCACGATCAACTCAGTACGTTCGGGATCGGTGCGGCGCTGTCGGAGCCCGAGTGGCGCGCGATTTTCCGGCAG
CTCGTCGCGTACGGCTATCTCGCAGTCGATCACGGCGGATTCGGCGCGCTCGTGCTGACCGAAGCCGCGAAGCCCGTGTT
GAAGGGCGACGAGAAGGTCACGCTGCGACGCTACGTGAAGCCGCAGCGCACGCGCCAGTCGTCCGGCCGCAGCGGCACGC
GCGTCGATCCGACGGCCGGCATGGGCACACGCGAGCGCGCGCGCTGGGACGCGCTGCGCGCATGGCGCGCGGAGACGGCC
AAGGCCGACGGCGTGCCGGCCTACGTCATCTTCCACGACGCGACGCTCGCCGAGATCGCGCGCAATGCACCGGAGACGAT
CGACGATCTCCGCCATATCCCCGGCATGGGCGTGCGCAAGCTCGAGCGGTTCGGCGACGAGATCATCGACGTCGTCGAAT
CGGCCTGA

Upstream 100 bases:

>100_bases
CGCTGTCCGAACGGCGAACGTCGTGCGATTCGCCGCGCGCCGCGCGGGGCGGGTTGTTAAAATCGCGGTCATCGTTCCGC
CGTCCACGTTCTCATCATTC

Downstream 100 bases:

>100_bases
CACAGGCGTTCCGACCCTTCGGGTCATCGGTCGCGATCGGCGGAAAATCACGCAAGCCGTTGACTTAGTTGGTATTTCCG
GAATATCATGCTGGGTTCCG

Product: ATP-dependent DNA helicase RecQ

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 615; Mature: 614

Protein sequence:

>615_residues
MSRALEILDEVFGYSAFRGQQGEIVEHVASGGDCLVLMPTGGGKSLCYQIPALMRREAGHGAGIVVSPLIALMQDQVAAL
REVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPERLMTGRFLELLERAKIGLFAIDEAHCVSQWGHDFRPEYIQL
SVLHERFPTVPRIALTATADAITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARAQLLDFIRAEHTNADGTTDAG
VVYCLSRRKVEETAEWLKAQGIRALPYHAGMDFEVRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEG
YYQETGRAGRDGLPANAWMAYGLGDVVQQRKMIDESDADDAHKRVQTSKLDALLGLCETISCRRVRLLNYFGEASQPCGN
CDTCLEPPASWDATREAQMALSCVFRAQRASGFNFGASHLIEILRGARTEKVLQRGHDQLSTFGIGAALSEPEWRAIFRQ
LVAYGYLAVDHGGFGALVLTEAAKPVLKGDEKVTLRRYVKPQRTRQSSGRSGTRVDPTAGMGTRERARWDALRAWRAETA
KADGVPAYVIFHDATLAEIARNAPETIDDLRHIPGMGVRKLERFGDEIIDVVESA

Sequences:

>Translated_615_residues
MSRALEILDEVFGYSAFRGQQGEIVEHVASGGDCLVLMPTGGGKSLCYQIPALMRREAGHGAGIVVSPLIALMQDQVAAL
REVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPERLMTGRFLELLERAKIGLFAIDEAHCVSQWGHDFRPEYIQL
SVLHERFPTVPRIALTATADAITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARAQLLDFIRAEHTNADGTTDAG
VVYCLSRRKVEETAEWLKAQGIRALPYHAGMDFEVRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEG
YYQETGRAGRDGLPANAWMAYGLGDVVQQRKMIDESDADDAHKRVQTSKLDALLGLCETISCRRVRLLNYFGEASQPCGN
CDTCLEPPASWDATREAQMALSCVFRAQRASGFNFGASHLIEILRGARTEKVLQRGHDQLSTFGIGAALSEPEWRAIFRQ
LVAYGYLAVDHGGFGALVLTEAAKPVLKGDEKVTLRRYVKPQRTRQSSGRSGTRVDPTAGMGTRERARWDALRAWRAETA
KADGVPAYVIFHDATLAEIARNAPETIDDLRHIPGMGVRKLERFGDEIIDVVESA
>Mature_614_residues
SRALEILDEVFGYSAFRGQQGEIVEHVASGGDCLVLMPTGGGKSLCYQIPALMRREAGHGAGIVVSPLIALMQDQVAALR
EVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPERLMTGRFLELLERAKIGLFAIDEAHCVSQWGHDFRPEYIQLS
VLHERFPTVPRIALTATADAITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARAQLLDFIRAEHTNADGTTDAGV
VYCLSRRKVEETAEWLKAQGIRALPYHAGMDFEVRQKHQEMFQREEGIVMCATIAFGMGIDKPDVRFVAHLDLPKSVEGY
YQETGRAGRDGLPANAWMAYGLGDVVQQRKMIDESDADDAHKRVQTSKLDALLGLCETISCRRVRLLNYFGEASQPCGNC
DTCLEPPASWDATREAQMALSCVFRAQRASGFNFGASHLIEILRGARTEKVLQRGHDQLSTFGIGAALSEPEWRAIFRQL
VAYGYLAVDHGGFGALVLTEAAKPVLKGDEKVTLRRYVKPQRTRQSSGRSGTRVDPTAGMGTRERARWDALRAWRAETAK
ADGVPAYVIFHDATLAEIARNAPETIDDLRHIPGMGVRKLERFGDEIIDVVESA

Specific function: Involved in the recF recombination pathway; its gene expression is under the regulation of the SOS system. It is a DNA helicase [H]

COG id: COG0514

COG function: function code L; Superfamily II DNA helicase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HRDC domain [H]

Homologues:

Organism=Homo sapiens, GI4557365, Length=654, Percent_Identity=34.2507645259939, Blast_Score=358, Evalue=1e-98,
Organism=Homo sapiens, GI14591902, Length=418, Percent_Identity=37.0813397129187, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI14591904, Length=418, Percent_Identity=37.0813397129187, Blast_Score=284, Evalue=1e-76,
Organism=Homo sapiens, GI148612816, Length=431, Percent_Identity=38.5150812064965, Blast_Score=270, Evalue=2e-72,
Organism=Homo sapiens, GI169218196, Length=565, Percent_Identity=32.0353982300885, Blast_Score=255, Evalue=8e-68,
Organism=Homo sapiens, GI110735439, Length=561, Percent_Identity=32.0855614973262, Blast_Score=254, Evalue=2e-67,
Organism=Homo sapiens, GI51242943, Length=401, Percent_Identity=38.4039900249377, Blast_Score=250, Evalue=3e-66,
Organism=Homo sapiens, GI51242947, Length=401, Percent_Identity=38.4039900249377, Blast_Score=250, Evalue=3e-66,
Organism=Homo sapiens, GI284005309, Length=347, Percent_Identity=35.7348703170029, Blast_Score=191, Evalue=1e-48,
Organism=Homo sapiens, GI148613856, Length=347, Percent_Identity=25.0720461095101, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI38201710, Length=347, Percent_Identity=25.0720461095101, Blast_Score=69, Evalue=2e-11,
Organism=Homo sapiens, GI21071032, Length=338, Percent_Identity=22.4852071005917, Blast_Score=67, Evalue=4e-11,
Organism=Escherichia coli, GI48994977, Length=618, Percent_Identity=45.7928802588997, Blast_Score=541, Evalue=1e-155,
Organism=Escherichia coli, GI87082221, Length=351, Percent_Identity=25.6410256410256, Blast_Score=69, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI25145561, Length=663, Percent_Identity=34.841628959276, Blast_Score=338, Evalue=4e-93,
Organism=Caenorhabditis elegans, GI71987997, Length=412, Percent_Identity=40.5339805825243, Blast_Score=300, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI71987993, Length=412, Percent_Identity=40.5339805825243, Blast_Score=300, Evalue=2e-81,
Organism=Caenorhabditis elegans, GI32564293, Length=672, Percent_Identity=31.1011904761905, Blast_Score=285, Evalue=4e-77,
Organism=Caenorhabditis elegans, GI17552866, Length=445, Percent_Identity=35.9550561797753, Blast_Score=253, Evalue=3e-67,
Organism=Caenorhabditis elegans, GI71995718, Length=352, Percent_Identity=23.5795454545455, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI71987143, Length=337, Percent_Identity=25.5192878338279, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17510309, Length=350, Percent_Identity=22.8571428571429, Blast_Score=69, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI17510307, Length=350, Percent_Identity=22.8571428571429, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71995514, Length=223, Percent_Identity=26.9058295964126, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI115533224, Length=351, Percent_Identity=22.7920227920228, Blast_Score=67, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6323844, Length=542, Percent_Identity=35.4243542435424, Blast_Score=348, Evalue=2e-96,
Organism=Saccharomyces cerevisiae, GI6324778, Length=338, Percent_Identity=24.2603550295858, Blast_Score=72, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6325138, Length=336, Percent_Identity=24.1071428571429, Blast_Score=69, Evalue=3e-12,
Organism=Drosophila melanogaster, GI24646066, Length=643, Percent_Identity=34.9922239502333, Blast_Score=355, Evalue=6e-98,
Organism=Drosophila melanogaster, GI24664226, Length=441, Percent_Identity=38.3219954648526, Blast_Score=268, Evalue=9e-72,
Organism=Drosophila melanogaster, GI62472181, Length=432, Percent_Identity=38.6574074074074, Blast_Score=265, Evalue=9e-71,
Organism=Drosophila melanogaster, GI24664230, Length=431, Percent_Identity=38.5150812064965, Blast_Score=265, Evalue=1e-70,
Organism=Drosophila melanogaster, GI21358123, Length=355, Percent_Identity=35.7746478873239, Blast_Score=209, Evalue=3e-54,
Organism=Drosophila melanogaster, GI28574962, Length=353, Percent_Identity=24.0793201133144, Blast_Score=66, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014001
- InterPro:   IPR011545
- InterPro:   IPR004589
- InterPro:   IPR006293
- InterPro:   IPR002121
- InterPro:   IPR001650
- InterPro:   IPR014021
- InterPro:   IPR010997
- InterPro:   IPR018982 [H]

Pfam domain/function: PF00270 DEAD; PF00271 Helicase_C; PF00570 HRDC; PF09382 RQC [H]

EC number: =3.6.4.12 [H]

Molecular weight: Translated: 68071; Mature: 67940

Theoretical pI: Translated: 6.42; Mature: 6.42

Prosite motif: PS50967 HRDC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.8 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.8 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRALEILDEVFGYSAFRGQQGEIVEHVASGGDCLVLMPTGGGKSLCYQIPALMRREAGH
CCHHHHHHHHHHCCHHCCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCC
GAGIVVSPLIALMQDQVAALREVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPER
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECHHH
LMTGRFLELLERAKIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPTVPRIALTATAD
HHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCCCEEHHHHHHHCCCCCCEEEEHHHH
AITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARAQLLDFIRAEHTNADGTTDAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCH
VVYCLSRRKVEETAEWLKAQGIRALPYHAGMDFEVRQKHQEMFQREEGIVMCATIAFGMG
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCC
IDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGLPANAWMAYGLGDVVQQRKMIDESDADD
CCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCCCHH
AHKRVQTSKLDALLGLCETISCRRVRLLNYFGEASQPCGNCDTCLEPPASWDATREAQMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LSCVFRAQRASGFNFGASHLIEILRGARTEKVLQRGHDQLSTFGIGAALSEPEWRAIFRQ
HHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHH
LVAYGYLAVDHGGFGALVLTEAAKPVLKGDEKVTLRRYVKPQRTRQSSGRSGTRVDPTAG
HHHHCEEEEECCCCCEEEEEHHCCHHHCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCCC
MGTRERARWDALRAWRAETAKADGVPAYVIFHDATLAEIARNAPETIDDLRHIPGMGVRK
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHCCCHHHHHHHHHCCCCCHHH
LERFGDEIIDVVESA
HHHHHHHHHHHHHCC
>Mature Secondary Structure 
SRALEILDEVFGYSAFRGQQGEIVEHVASGGDCLVLMPTGGGKSLCYQIPALMRREAGH
CHHHHHHHHHHCCHHCCCCCCHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHCCCC
GAGIVVSPLIALMQDQVAALREVGVRAAYLNSTLSGAEAAATERALREGEIDLLYVAPER
CCCHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEECHHH
LMTGRFLELLERAKIGLFAIDEAHCVSQWGHDFRPEYIQLSVLHERFPTVPRIALTATAD
HHHHHHHHHHHHCCCCEEEECHHHHHHHCCCCCCCCCEEHHHHHHHCCCCCCEEEEHHHH
AITRDEIIHRLALDDARVFVSSFDRPNIRYRIVEKDNARAQLLDFIRAEHTNADGTTDAG
HHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHCCCCCCCCCCH
VVYCLSRRKVEETAEWLKAQGIRALPYHAGMDFEVRQKHQEMFQREEGIVMCATIAFGMG
HHHHHHHHHHHHHHHHHHHCCCEECCCCCCCCHHHHHHHHHHHHHCCCEEEEEEHHHHCC
IDKPDVRFVAHLDLPKSVEGYYQETGRAGRDGLPANAWMAYGLGDVVQQRKMIDESDADD
CCCCCCEEEEEECCCHHHHHHHHHCCCCCCCCCCCHHHHHHCHHHHHHHHHHCCCCCCHH
AHKRVQTSKLDALLGLCETISCRRVRLLNYFGEASQPCGNCDTCLEPPASWDATREAQMA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCHHHHHHH
LSCVFRAQRASGFNFGASHLIEILRGARTEKVLQRGHDQLSTFGIGAALSEPEWRAIFRQ
HHHHHHHHHCCCCCCCHHHHHHHHHCCHHHHHHHCCCHHHHHHCCCCCCCCCHHHHHHHH
LVAYGYLAVDHGGFGALVLTEAAKPVLKGDEKVTLRRYVKPQRTRQSSGRSGTRVDPTAG
HHHHCEEEEECCCCCEEEEEHHCCHHHCCCCHHHHHHHCCHHHHHHCCCCCCCCCCCCCC
MGTRERARWDALRAWRAETAKADGVPAYVIFHDATLAEIARNAPETIDDLRHIPGMGVRK
CCCHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHCCCHHHHHHHHHCCCCCHHH
LERFGDEIIDVVESA
HHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3027506; 1379743; 9278503; 2164680 [H]