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The map label for this gene is flhA [H]

Identifier: 161523356

GI number: 161523356

Start: 197374

End: 199476

Strand: Direct

Name: flhA [H]

Synonym: Bmul_0176

Alternate gene names: 161523356

Gene position: 197374-199476 (Clockwise)

Preceding gene: 161523355

Following gene: 161523357

Centisome position: 5.72

GC content: 67.28

Gene sequence:

>2103_bases
ATGAGCACGCCGACCACGGGGCTCTTCGCGAAGCGCGCGACCCTGCTCGCCGGCACGAACCTGCGCGCGCTGGCCGGGCC
GATCCTGATCTGCATGATCCTCGGGATGATGATCCTGCCGCTGCCGCCGTTGCTGCTGGATCTGCTGTTCACGTTCAACA
TCGCGCTGTCGGTGATGGTGCTGCTCGTCAGCATGTACACGATGAAGCCGCTCGACTTCGCGGCATTCCCGAGCGTGCTG
CTGTTCTCGACGCTGCTGCGGCTGTCGCTGAACGTCGCGTCGACGCGCGTCGTGCTGCTCGAAGGCCACACGGGCCCGGA
CGCGGCCGGCCAGGTCATCGAGGCGTTCGGCCACTTCCTCGTCGGCGGCAATTTCGCGGTCGGCATCGTCGTGTTCGTGA
TTCTGATGATCATCAACTTCATGGTGATCACGAAGGGCGCGGGGCGCATCGCCGAAGTGTCCGCGCGCTTTACGCTCGAC
GCGATGCCCGGCAAGCAGATGGCGATCGACGCCGATCTGAACGCGGGCCTCATCAACGAGGAGCAGGCGCGCAAGCGCCG
CCAGGCCGTCGCGCAGGAGGCCGAGTTCTACGGCTCGATGGACGGCGCGTCGAAGTTCGTGCGCGGCGACGCGATCGCCG
GCCTGATCATCATGGCGATCAACGTGATCGGCGGCCTGATCGTCGGGATGATCCAGCACGACATGAGCTTCGCGGCCGCG
GGCAAGAACTACACGCTGCTGACGATCGGCGACGGCCTCGTCGCGCAGATTCCGTCGCTCGTGATCTCGACCGCGGCCGG
CGTGATCGTGTCGCGCGTCGCGACCGATGAGGACATCGGCACGCAGATCACCGGCCAGCTGTTCACGAACCCGCGCGTGC
TGACGATCACGGGCGCGATCATCGTGCTGATGGGGCTGATTCCCGGCATGCCGCACTTCGCGTTTCTCGCGCTCGGCGGC
GGCGCGATCTGGCTCGCCCGCACGCAGACGAAGCGCGCGGCCGCGCGCAAGGCGGCCGGCGACGTGACCGAGATCGCACC
GCCCGCCGCGCTGCCGTCCGACAGCCACGAAGCGACGTGGGACGACGTGCAGCTGATCGATCCGCTCGGCCTCGAAGTCG
GCTATCGGCTGATTCCGCTCGTCGATCGCAACAGCGACGGCGAGCTGCTCAAGCGGATCAAGAGCATCCGCAAGAAATTC
GCGCAGGAAATCGGCTTCCTGCCGCCGGTGATCCATATCCGCGACAACCTCGAACTGCGTCCGAACGCGTACCGGATCGC
GCTGAAGGGCGTCGAGATCGGCACGGGCGAAGTGTTTCCGGGCCAGTGGCTCGCGATCAATCCGGGGCAGGTGACGGCCG
CGCTGCCGGGCGCCGCGACGCAGGATCCGGCGTTCGGGCTGCCGGCCGTATGGATCGACGTCGCGATGCGCGAGCAGGCG
CAGGTGTACGGCTACACGGTCGTCGATGCGAGCACCGTGGTCGCGACGCACCTGAACCATCTGGTCGTCCAGCACGCGGC
CGAGCTGCTCGGCCGGCAGGAAGTGCAGGCGCTCGTCGAGCGCACCGGCAAGGATGCACCGTCGCTCGTCGAGGATCTGG
TGCCGAAGACGGTCTCGCTGACGACGCTGCAGAAGGTGCTGCAGAACCTGCTCGACGAAGGCGTGCCGATCCGCGACATG
CGCACGATCCTCGAGGCCGTGTCCGAGCATGCGGGCCGCGGCGACGCATACGAGATCACGGCCGCCGTGCGCCTCGCGCT
CGGCCGCGCGATCACGCAGCAGTGGTATCCGGGCACGGGCGACATGCAGGTGATGGGTCTCGACGCGAATCTCGAGCGCG
TGCTGTCGCAGGCGCTTGCCACCGGCGCGAATCCGGGCCTCGAGCCCGGCCTCGCGAACACGCTTCTGACCGGCACGCAA
CAGGCGATGCTGCGTCAACAGAATCTCGGGCTGCCGCCCGTGCTGCTCGTGCAGCACGCGTTGCGCGCGATGCTCGCGCG
CTTCCTGCGCCGCAGCCTGCCGCAATTGAAAGTGCTGTCGTATGCCGAAGTGCCGGATACACGCACGATCAAGGTTGTTA
ACGTCATCGGGGGTTCCGCTTGA

Upstream 100 bases:

>100_bases
ATCTCGACGTGCCGGCCGAACTCGACAAGGGCGCGACGGTGTCCGCCGACGACGCGCGCGACGAGGCCGAAGACGCGCTC
GGCACGCACGGAGGCGCCGC

Downstream 100 bases:

>100_bases
ACATTCGCAAATTCACCGGCGCGACGAGCCGCGACGCGCTTCGTCTGGTGCGCGAGGCGCTGGGCGCCGACGCCGTCGTG
CTGTCGAACCGTGCGCTCGA

Product: flagellar biosynthesis protein FlhA

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 700; Mature: 699

Protein sequence:

>700_residues
MSTPTTGLFAKRATLLAGTNLRALAGPILICMILGMMILPLPPLLLDLLFTFNIALSVMVLLVSMYTMKPLDFAAFPSVL
LFSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLVGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLD
AMPGKQMAIDADLNAGLINEEQARKRRQAVAQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMIQHDMSFAAA
GKNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLTITGAIIVLMGLIPGMPHFAFLALGG
GAIWLARTQTKRAAARKAAGDVTEIAPPAALPSDSHEATWDDVQLIDPLGLEVGYRLIPLVDRNSDGELLKRIKSIRKKF
AQEIGFLPPVIHIRDNLELRPNAYRIALKGVEIGTGEVFPGQWLAINPGQVTAALPGAATQDPAFGLPAVWIDVAMREQA
QVYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALVERTGKDAPSLVEDLVPKTVSLTTLQKVLQNLLDEGVPIRDM
RTILEAVSEHAGRGDAYEITAAVRLALGRAITQQWYPGTGDMQVMGLDANLERVLSQALATGANPGLEPGLANTLLTGTQ
QAMLRQQNLGLPPVLLVQHALRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA

Sequences:

>Translated_700_residues
MSTPTTGLFAKRATLLAGTNLRALAGPILICMILGMMILPLPPLLLDLLFTFNIALSVMVLLVSMYTMKPLDFAAFPSVL
LFSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLVGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLD
AMPGKQMAIDADLNAGLINEEQARKRRQAVAQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMIQHDMSFAAA
GKNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLTITGAIIVLMGLIPGMPHFAFLALGG
GAIWLARTQTKRAAARKAAGDVTEIAPPAALPSDSHEATWDDVQLIDPLGLEVGYRLIPLVDRNSDGELLKRIKSIRKKF
AQEIGFLPPVIHIRDNLELRPNAYRIALKGVEIGTGEVFPGQWLAINPGQVTAALPGAATQDPAFGLPAVWIDVAMREQA
QVYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALVERTGKDAPSLVEDLVPKTVSLTTLQKVLQNLLDEGVPIRDM
RTILEAVSEHAGRGDAYEITAAVRLALGRAITQQWYPGTGDMQVMGLDANLERVLSQALATGANPGLEPGLANTLLTGTQ
QAMLRQQNLGLPPVLLVQHALRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA
>Mature_699_residues
STPTTGLFAKRATLLAGTNLRALAGPILICMILGMMILPLPPLLLDLLFTFNIALSVMVLLVSMYTMKPLDFAAFPSVLL
FSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFLVGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDA
MPGKQMAIDADLNAGLINEEQARKRRQAVAQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMIQHDMSFAAAG
KNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLTITGAIIVLMGLIPGMPHFAFLALGGG
AIWLARTQTKRAAARKAAGDVTEIAPPAALPSDSHEATWDDVQLIDPLGLEVGYRLIPLVDRNSDGELLKRIKSIRKKFA
QEIGFLPPVIHIRDNLELRPNAYRIALKGVEIGTGEVFPGQWLAINPGQVTAALPGAATQDPAFGLPAVWIDVAMREQAQ
VYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALVERTGKDAPSLVEDLVPKTVSLTTLQKVLQNLLDEGVPIRDMR
TILEAVSEHAGRGDAYEITAAVRLALGRAITQQWYPGTGDMQVMGLDANLERVLSQALATGANPGLEPGLANTLLTGTQQ
AMLRQQNLGLPPVLLVQHALRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA

Specific function: Required for formation of the rod structure of the flagellar apparatus. Together with fliI and fliH, may constitute the export apparatus of flagellin [H]

COG id: COG1298

COG function: function code NU; Flagellar biosynthesis pathway, component FlhA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family [H]

Homologues:

Organism=Escherichia coli, GI1788187, Length=688, Percent_Identity=65.9883720930232, Blast_Score=894, Evalue=0.0,

Paralogues:

None

Copy number: 10-20 (rich media) [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006301
- InterPro:   IPR001712 [H]

Pfam domain/function: PF00771 FHIPEP [H]

EC number: NA

Molecular weight: Translated: 74665; Mature: 74533

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: PS00994 FHIPEP

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.1 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.1 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTPTTGLFAKRATLLAGTNLRALAGPILICMILGMMILPLPPLLLDLLFTFNIALSVMV
CCCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LLVSMYTMKPLDFAAFPSVLLFSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
VGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLINE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEECCCCCCEEEECCCCCCCCCH
EQARKRRQAVAQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMIQHDMSFAAA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GKNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLTITGAI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHEECCCEEEEEHHHH
IVLMGLIPGMPHFAFLALGGGAIWLARTQTKRAAARKAAGDVTEIAPPAALPSDSHEATW
HHHHHHHCCCCHHHHHEECCCEEEEEECHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCC
DDVQLIDPLGLEVGYRLIPLVDRNSDGELLKRIKSIRKKFAQEIGFLPPVIHIRDNLELR
CCHHHCCCCCHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEC
PNAYRIALKGVEIGTGEVFPGQWLAINPGQVTAALPGAATQDPAFGLPAVWIDVAMREQA
CCEEEEEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
QVYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALVERTGKDAPSLVEDLVPKTVSL
HHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHH
TTLQKVLQNLLDEGVPIRDMRTILEAVSEHAGRGDAYEITAAVRLALGRAITQQWYPGTG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
DMQVMGLDANLERVLSQALATGANPGLEPGLANTLLTGTQQAMLRQQNLGLPPVLLVQHA
CEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA
HHHHHHHHHHHCCCCEEHHHHCCCCCCCEEEEEEECCCCC
>Mature Secondary Structure 
STPTTGLFAKRATLLAGTNLRALAGPILICMILGMMILPLPPLLLDLLFTFNIALSVMV
CCCCCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHH
LLVSMYTMKPLDFAAFPSVLLFSTLLRLSLNVASTRVVLLEGHTGPDAAGQVIEAFGHFL
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHHH
VGGNFAVGIVVFVILMIINFMVITKGAGRIAEVSARFTLDAMPGKQMAIDADLNAGLINE
CCCCHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHEEEEEECCCCCCEEEECCCCCCCCCH
EQARKRRQAVAQEAEFYGSMDGASKFVRGDAIAGLIIMAINVIGGLIVGMIQHDMSFAAA
HHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
GKNYTLLTIGDGLVAQIPSLVISTAAGVIVSRVATDEDIGTQITGQLFTNPRVLTITGAI
CCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEHHEECCCEEEEEHHHH
IVLMGLIPGMPHFAFLALGGGAIWLARTQTKRAAARKAAGDVTEIAPPAALPSDSHEATW
HHHHHHHCCCCHHHHHEECCCEEEEEECHHHHHHHHHHCCCHHHCCCCCCCCCCCCCCCC
DDVQLIDPLGLEVGYRLIPLVDRNSDGELLKRIKSIRKKFAQEIGFLPPVIHIRDNLELR
CCHHHCCCCCHHCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHCCCCCCEEEECCCCEEC
PNAYRIALKGVEIGTGEVFPGQWLAINPGQVTAALPGAATQDPAFGLPAVWIDVAMREQA
CCEEEEEEEEEEECCCCCCCCCEEEECCCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHH
QVYGYTVVDASTVVATHLNHLVVQHAAELLGRQEVQALVERTGKDAPSLVEDLVPKTVSL
HHEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCHH
TTLQKVLQNLLDEGVPIRDMRTILEAVSEHAGRGDAYEITAAVRLALGRAITQQWYPGTG
HHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCC
DMQVMGLDANLERVLSQALATGANPGLEPGLANTLLTGTQQAMLRQQNLGLPPVLLVQHA
CEEEEECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHH
LRAMLARFLRRSLPQLKVLSYAEVPDTRTIKVVNVIGGSA
HHHHHHHHHHHCCCCEEHHHHCCCCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9097040; 9278503 [H]