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The map label for this gene is cheA [H]

Identifier: 161523345

GI number: 161523345

Start: 184963

End: 187248

Strand: Direct

Name: cheA [H]

Synonym: Bmul_0165

Alternate gene names: 161523345

Gene position: 184963-187248 (Clockwise)

Preceding gene: 161523344

Following gene: 161523346

Centisome position: 5.36

GC content: 69.82

Gene sequence:

>2286_bases
ATGACTCTCGACATCACTCAGTTCTACCAGACATTCTTCGACGAAGCGGACGAGCTGCTCGCGCAGATGGAGCAACTGCT
GCTGAACCTCGACGTCGGCGCGCCCGACGCCGAGGATCTGGCCGCGATCTTTCGGGCCGCGCATTCGATCAAGGGCGGCG
CGGCGACGTTCGGGTTCTCGGCGCTGACCGACACCACGCACATTCTCGAATCGCTGCTCGACCGCGCGCGCAACCACGAG
CTGACGCTGACGAAGGAAATGGTCGACGCGTTCCTCGAGACGAAGGACGTGCTGTCCGACCAACTCGCCGACTATCGCGC
GAGCGCGGAACCCGACGCGGCGGCCGCCGCGGCGATCTGCGCGAAGCTCGAGCGGCTGCAGGCCGATAGCGGCGGCGCGG
CGGCATCGGTGGCCGCACCGGCGGCGGTCGCCGTCGCGGCGCCCGCTTCCGCAGCGCCGGCCGTTGCGCCCGCAGCGGAC
GGCCAGCGCGCGCCCGACCATGTCGTCGAGCAGGCGGTCGCGGCCGCGCATCCGTCCGCAGCGGGCGCAGCGGCACCGCA
GACCGACGCCGCCGATGAGGGCGACAGCAACGGCGACGGCCCGCACCTGAAGATCACGCTGACGGGCGTCGACGCGAAGG
ATCAGGCGCTGCTCGTCGAGGAACTCGGCAATCTCGGTCGGATCGTCGGCCGCACGGAAGTCGGCGACGCGCTGACGCTG
TGGCTCGAATCCGACGTGCCGTCCGACGACATCGTCGCGGTGTGCTGCTTCGTGATCGACGAAAGCCAGATCCGGATCGC
GCGCGGCGCGGCGCCGGCCGCCACGCAGCCGGCCGCGGCCGCACAGGTCGTCGCCGAACCGCCGCATGGCGAAGCCGCGC
CGCAACCGGCCGCGCCGGCAGCGGCACCCGCAGCAACCGCCGCGGCACCGGCCGCAACGCCTGCCGCATCGACCGCATCG
GCTGCACCGGCCGCCGCGCCTGCCGCGCACGCCGAATCGCCCGCGCCGTCCGCGGCCGCGCAGCCGGCCGCCCATCACGA
CGACAAGCGCGCACGTCCGGCCGCAGCCGCCGCGGCGGGCGCGGAAGGCAGTTCGATCCGCGTCGGCGTCGAGAAGGTCG
ATCAGCTGATCAACCTCGTCGGCGAACTCGTGATCACGCAGGCGATGCTCGCCGAGACGGCGAGCGCGTTCGACCCGGCA
CTGCACGACCGCCTGTTCAACGGGATGGCGCAGCTCGAGCGCAACGCGCGCGACCTGCAGGAAGCCGTGATGTCGATCCG
CATGATGCCGATGGATTACGTGTTCAGCCGCTTCCCGCGCCTCGTGCGCGATCTCGCGGGCAAGCTCGGCAAGCAGGTCG
AACTGGTTACGTTCGGTCAGGCGACCGAACTCGACAAGAGCCTGATCGAGCGCATCATCGATCCGCTCACGCACCTCGTG
CGCAACAGCCTCGACCACGGCATCGAGACGGTCGACAAGCGGATCGCGGCCGGCAAGGACGCGGTCGGCCAGCTCGTGCT
GTCGGCCGCGCATCACGGCGGCAACATCGTGATCGAGGTCAGCGACGACGGCGCGGGCCTGAACCGCGAGCGGATCCTGG
CCAAAGCCGCGAAGCAGGGCATGCAGATTCCCGAGAACATCAGCGACGACGAAGTCTGGCAGCTGATCTTCGCGCCGGGC
TTCTCGACCGCCGAGACGGTAACGGACGTGTCGGGCCGCGGCGTCGGCATGGACGTCGTGAAGCGCAACATCCAGTCGAT
GGGCGGCCACGTCGAGATCTCGTCGCAGGCCGGGCGCGGCACGACCACGCGGATCGTGCTGCCGCTCACGCTCGCGATTC
TCGACGGGATGTCGGTGAAGGTCGGCAGCGAGATCTTCATCCTGCCGCTGAACTTCGTGATGGAGTCGCTGCAGCCGTCG
AACGACGACATCTACACGGTCGGCAACGGCGAGCGTGTGGTGCGCGTGCGCGGCGAATACCTGCCGCTCGTCGCGCTGCA
CGAGGTGTTCTCGGTCGAGGGCGCGCGCACCGATCCGACGCAGGGGATCGTCACGATCATGGAAACCGAGGGGCGCCGCT
TCGCGATGCTGATCGACGAGCTGGTCGGCCAGCAGCAGGTCGTCGTGAAGAACCTCGAAACCAACTACCGCAAGGTGCAC
GGCATCTCGGCGGCGACCATCCTCGGCGACGGCAGCGTCGCGCTGATCGTCGACGTCGCGGCGCTGAACCGCGAAACCCG
TGCGACGCACGGTGCCCGGGCGGGCGCCGAGCTCGCGATGTTCTGA

Upstream 100 bases:

>100_bases
AAAGCCGATCGACCCGGGCGTGCTCGTCGAGCTTGTCGCGACGCTGTCCGAGCCGGCCGCCAATTGACATGAACGCGATG
AACCCAACCGGTGACCGGGC

Downstream 100 bases:

>100_bases
CTCTCGCCATCAACCGATTGGGGGCAAACGTGTCTGCTGAAGTCCAAATGATCAATCCGGCCGCGGCGAACGCGGCCAAT
GCGACGACCGGCCGCCGCGA

Product: CheA signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 761; Mature: 760

Protein sequence:

>761_residues
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVGAPDAEDLAAIFRAAHSIKGGAATFGFSALTDTTHILESLLDRARNHE
LTLTKEMVDAFLETKDVLSDQLADYRASAEPDAAAAAAICAKLERLQADSGGAAASVAAPAAVAVAAPASAAPAVAPAAD
GQRAPDHVVEQAVAAAHPSAAGAAAPQTDAADEGDSNGDGPHLKITLTGVDAKDQALLVEELGNLGRIVGRTEVGDALTL
WLESDVPSDDIVAVCCFVIDESQIRIARGAAPAATQPAAAAQVVAEPPHGEAAPQPAAPAAAPAATAAAPAATPAASTAS
AAPAAAPAAHAESPAPSAAAQPAAHHDDKRARPAAAAAAGAEGSSIRVGVEKVDQLINLVGELVITQAMLAETASAFDPA
LHDRLFNGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLV
RNSLDHGIETVDKRIAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQIPENISDDEVWQLIFAPG
FSTAETVTDVSGRGVGMDVVKRNIQSMGGHVEISSQAGRGTTTRIVLPLTLAILDGMSVKVGSEIFILPLNFVMESLQPS
NDDIYTVGNGERVVRVRGEYLPLVALHEVFSVEGARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVH
GISAATILGDGSVALIVDVAALNRETRATHGARAGAELAMF

Sequences:

>Translated_761_residues
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVGAPDAEDLAAIFRAAHSIKGGAATFGFSALTDTTHILESLLDRARNHE
LTLTKEMVDAFLETKDVLSDQLADYRASAEPDAAAAAAICAKLERLQADSGGAAASVAAPAAVAVAAPASAAPAVAPAAD
GQRAPDHVVEQAVAAAHPSAAGAAAPQTDAADEGDSNGDGPHLKITLTGVDAKDQALLVEELGNLGRIVGRTEVGDALTL
WLESDVPSDDIVAVCCFVIDESQIRIARGAAPAATQPAAAAQVVAEPPHGEAAPQPAAPAAAPAATAAAPAATPAASTAS
AAPAAAPAAHAESPAPSAAAQPAAHHDDKRARPAAAAAAGAEGSSIRVGVEKVDQLINLVGELVITQAMLAETASAFDPA
LHDRLFNGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLV
RNSLDHGIETVDKRIAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQIPENISDDEVWQLIFAPG
FSTAETVTDVSGRGVGMDVVKRNIQSMGGHVEISSQAGRGTTTRIVLPLTLAILDGMSVKVGSEIFILPLNFVMESLQPS
NDDIYTVGNGERVVRVRGEYLPLVALHEVFSVEGARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVH
GISAATILGDGSVALIVDVAALNRETRATHGARAGAELAMF
>Mature_760_residues
TLDITQFYQTFFDEADELLAQMEQLLLNLDVGAPDAEDLAAIFRAAHSIKGGAATFGFSALTDTTHILESLLDRARNHEL
TLTKEMVDAFLETKDVLSDQLADYRASAEPDAAAAAAICAKLERLQADSGGAAASVAAPAAVAVAAPASAAPAVAPAADG
QRAPDHVVEQAVAAAHPSAAGAAAPQTDAADEGDSNGDGPHLKITLTGVDAKDQALLVEELGNLGRIVGRTEVGDALTLW
LESDVPSDDIVAVCCFVIDESQIRIARGAAPAATQPAAAAQVVAEPPHGEAAPQPAAPAAAPAATAAAPAATPAASTASA
APAAAPAAHAESPAPSAAAQPAAHHDDKRARPAAAAAAGAEGSSIRVGVEKVDQLINLVGELVITQAMLAETASAFDPAL
HDRLFNGMAQLERNARDLQEAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLVR
NSLDHGIETVDKRIAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQGMQIPENISDDEVWQLIFAPGF
STAETVTDVSGRGVGMDVVKRNIQSMGGHVEISSQAGRGTTTRIVLPLTLAILDGMSVKVGSEIFILPLNFVMESLQPSN
DDIYTVGNGERVVRVRGEYLPLVALHEVFSVEGARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVHG
ISAATILGDGSVALIVDVAALNRETRATHGARAGAELAMF

Specific function: Involved in the transmission of sensory signals from the chemoreceptors to the flagellar motors. CheA is autophosphorylated; it can transfer its phosphate group to either CheB or CheY [H]

COG id: COG0643

COG function: function code NT; Chemotaxis protein histidine kinase and related kinases

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HPt domain [H]

Homologues:

Organism=Escherichia coli, GI1788197, Length=755, Percent_Identity=55.2317880794702, Blast_Score=758, Evalue=0.0,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR002545
- InterPro:   IPR015162
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR004105
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF01584 CheW; PF09078 CheY-binding; PF02895 H-kinase_dim; PF02518 HATPase_c; PF01627 Hpt [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 79197; Mature: 79066

Theoretical pI: Translated: 4.51; Mature: 4.51

Prosite motif: PS50851 CHEW ; PS50894 HPT ; PS00039 DEAD_ATP_HELICASE ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTLDITQFYQTFFDEADELLAQMEQLLLNLDVGAPDAEDLAAIFRAAHSIKGGAATFGFS
CCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCHH
ALTDTTHILESLLDRARNHELTLTKEMVDAFLETKDVLSDQLADYRASAEPDAAAAAAIC
HHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AKLERLQADSGGAAASVAAPAAVAVAAPASAAPAVAPAADGQRAPDHVVEQAVAAAHPSA
HHHHHHHCCCCCCCHHHHCCHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
AGAAAPQTDAADEGDSNGDGPHLKITLTGVDAKDQALLVEELGNLGRIVGRTEVGDALTL
CCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHCCHHHHHCCCCCCCEEEE
WLESDVPSDDIVAVCCFVIDESQIRIARGAAPAATQPAAAAQVVAEPPHGEAAPQPAAPA
EEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCC
AAPAATAAAPAATPAASTASAAPAAAPAAHAESPAPSAAAQPAAHHDDKRARPAAAAAAG
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCC
AEGSSIRVGVEKVDQLINLVGELVITQAMLAETASAFDPALHDRLFNGMAQLERNARDLQ
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
RNSLDHGIETVDKRIAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCC
MQIPENISDDEVWQLIFAPGFSTAETVTDVSGRGVGMDVVKRNIQSMGGHVEISSQAGRG
CCCCCCCCHHHHEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCC
TTTRIVLPLTLAILDGMSVKVGSEIFILPLNFVMESLQPSNDDIYTVGNGERVVRVRGEY
CCEEEHHHHHHHHHCCCCEEECCEEEEEEHHHHHHHCCCCCCCEEEECCCCEEEEECCCC
LPLVALHEVFSVEGARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVH
CCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHC
GISAATILGDGSVALIVDVAALNRETRATHGARAGAELAMF
CCEEEEEECCCCEEEEEEHHHHCCHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
TLDITQFYQTFFDEADELLAQMEQLLLNLDVGAPDAEDLAAIFRAAHSIKGGAATFGFS
CCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCCHHCCHH
ALTDTTHILESLLDRARNHELTLTKEMVDAFLETKDVLSDQLADYRASAEPDAAAAAAIC
HHHHHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHH
AKLERLQADSGGAAASVAAPAAVAVAAPASAAPAVAPAADGQRAPDHVVEQAVAAAHPSA
HHHHHHHCCCCCCCHHHHCCHHHEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCC
AGAAAPQTDAADEGDSNGDGPHLKITLTGVDAKDQALLVEELGNLGRIVGRTEVGDALTL
CCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHCCHHHHHCCCCCCCEEEE
WLESDVPSDDIVAVCCFVIDESQIRIARGAAPAATQPAAAAQVVAEPPHGEAAPQPAAPA
EEECCCCCHHHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHHHCCCCCCCCCCCCCCCC
AAPAATAAAPAATPAASTASAAPAAAPAAHAESPAPSAAAQPAAHHDDKRARPAAAAAAG
CCCCHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHCC
AEGSSIRVGVEKVDQLINLVGELVITQAMLAETASAFDPALHDRLFNGMAQLERNARDLQ
CCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
EAVMSIRMMPMDYVFSRFPRLVRDLAGKLGKQVELVTFGQATELDKSLIERIIDPLTHLV
HHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCEEEEEECCCHHHHHHHHHHHHHHHHHHHH
RNSLDHGIETVDKRIAAGKDAVGQLVLSAAHHGGNIVIEVSDDGAGLNRERILAKAAKQG
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHHHHHHCC
MQIPENISDDEVWQLIFAPGFSTAETVTDVSGRGVGMDVVKRNIQSMGGHVEISSQAGRG
CCCCCCCCHHHHEEEEECCCCCHHHHHHCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCC
TTTRIVLPLTLAILDGMSVKVGSEIFILPLNFVMESLQPSNDDIYTVGNGERVVRVRGEY
CCEEEHHHHHHHHHCCCCEEECCEEEEEEHHHHHHHCCCCCCCEEEECCCCEEEEECCCC
LPLVALHEVFSVEGARTDPTQGIVTIMETEGRRFAMLIDELVGQQQVVVKNLETNYRKVH
CCHHHHHHHHHCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHHC
GISAATILGDGSVALIVDVAALNRETRATHGARAGAELAMF
CCEEEEEECCCCEEEEEEHHHHCCHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 3278311; 11677609 [H]