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The map label for this gene is namA [H]

Identifier: 161523252

GI number: 161523252

Start: 77885

End: 78997

Strand: Direct

Name: namA [H]

Synonym: Bmul_0072

Alternate gene names: 161523252

Gene position: 77885-78997 (Clockwise)

Preceding gene: 161523251

Following gene: 161523253

Centisome position: 2.26

GC content: 69.36

Gene sequence:

>1113_bases
ATGACTGCGCTGTTTTCACCGTTCACGCTGCGCGGCGTGACCTTGCCGAACCGGATCGTGATTTCGCCGATGTGCCAGTA
TTCCGCGGAGCGCGGCGAAGCGACCGACTGGCACATGATTCACCTCGGCCATCTCGCGCTGTCCGGCGCGGCGCTGCTTT
GCATCGAGGCGACCGCGGTCGAACCCGACGGCCGCATCACGCACGGCGACCTCGGCCTCTGGGACGACGCGACCGAAGCG
GCGCTGAAGCCCGTCCTCGCTGCAATCCGCCGCTACTCGCCGATTCGCGTCGCGATGCAGCTGTCGCATGCGGGACGCAA
GGCGTCGAGCGAGGTGCCGTGGAAGGGCGGGCAACTGGTGCCCGTCGCCGAGGGCGGCTGGCTGCCGCATGCGCCGTCGG
CCGTTCCGCACAAGGACGGCGAGACGCCGCCGCTCGCGCTCGACGCGGCCGGGCTGAATCGTGTCCGCGAGGCATTCGCT
GCGTCCGCGAAACGTGCGGCGCGGCTCGGCATCGACGCGATCGAGGTGCATGCGGCGCACGGCTATCTGCTGCATCAGTT
CCTGTCGCCGCTCGCGAACCGGCGCACCGACGAATACGGCGGCTCGCGCGAAAACCGCATGCGTTTTCCGCTCGAGATCT
TCGACATCGTGCGTGCCGCGTTTCCGGAGGATCGGCCGGTCGGCGTGCGCGTGTCCGCGACGGACTGGGTCGAAGGCGGC
TGGGAGCTCGAGGACACGATCGCATTCGCGCACGAACTGAAGCGCCGCGGCTGCGACTGGATCGACGTGTCGTCGGGCGG
CGTATCGCCGTTGCAGAAGATTCCGCTGTCGCCCGGCTATCAGGTGCCGTTCGCGCAGGCCGTGAAGCGCGCGGTCGACA
TGCCGACGATCGCGGTGGGCCTCATCAACGAGCCCGCGCATGCGAACCGCTTGATCGAAGCGGGCGATGCGGACTTCGTC
GCGATGGCGCGTGCGATGCTGTACGACCCGCGCTGGCCGTGGCACGCGGCCGCCGAACTCGGCGCGCAGGTGTCGGCGCC
GCCGCAGTACTGGCGCTCGCAGCCGCGCGAACACAAGGCGCTGTTCGGCGACATCGCATTCGGCCAGCGCTGA

Upstream 100 bases:

>100_bases
CACGTTCCTGACCAATCGCTTACTGCCGTTGCCGCCGTCTGCAGGCATCGGTCGTGCGTGCTACGCTCGTGCGCTCTTCC
ATTTCTCGAGAGCGGCCACC

Downstream 100 bases:

>100_bases
GCGACACGCGCCATCGCACGCGATGTTGAACGAAGCAATCGCGAACGTGTAGGATGCGGGTGATTCGCCGCATGCCCCGA
CGCGGCACCGACCGGTGCCG

Product: NADH:flavin oxidoreductase/NADH oxidase

Products: NA

Alternate protein names: Xenobiotic reductase [H]

Number of amino acids: Translated: 370; Mature: 369

Protein sequence:

>370_residues
MTALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAALLCIEATAVEPDGRITHGDLGLWDDATEA
ALKPVLAAIRRYSPIRVAMQLSHAGRKASSEVPWKGGQLVPVAEGGWLPHAPSAVPHKDGETPPLALDAAGLNRVREAFA
ASAKRAARLGIDAIEVHAAHGYLLHQFLSPLANRRTDEYGGSRENRMRFPLEIFDIVRAAFPEDRPVGVRVSATDWVEGG
WELEDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRAVDMPTIAVGLINEPAHANRLIEAGDADFV
AMARAMLYDPRWPWHAAAELGAQVSAPPQYWRSQPREHKALFGDIAFGQR

Sequences:

>Translated_370_residues
MTALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAALLCIEATAVEPDGRITHGDLGLWDDATEA
ALKPVLAAIRRYSPIRVAMQLSHAGRKASSEVPWKGGQLVPVAEGGWLPHAPSAVPHKDGETPPLALDAAGLNRVREAFA
ASAKRAARLGIDAIEVHAAHGYLLHQFLSPLANRRTDEYGGSRENRMRFPLEIFDIVRAAFPEDRPVGVRVSATDWVEGG
WELEDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRAVDMPTIAVGLINEPAHANRLIEAGDADFV
AMARAMLYDPRWPWHAAAELGAQVSAPPQYWRSQPREHKALFGDIAFGQR
>Mature_369_residues
TALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAALLCIEATAVEPDGRITHGDLGLWDDATEAA
LKPVLAAIRRYSPIRVAMQLSHAGRKASSEVPWKGGQLVPVAEGGWLPHAPSAVPHKDGETPPLALDAAGLNRVREAFAA
SAKRAARLGIDAIEVHAAHGYLLHQFLSPLANRRTDEYGGSRENRMRFPLEIFDIVRAAFPEDRPVGVRVSATDWVEGGW
ELEDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRAVDMPTIAVGLINEPAHANRLIEAGDADFVA
MARAMLYDPRWPWHAAAELGAQVSAPPQYWRSQPREHKALFGDIAFGQR

Specific function: Catalyzes the reduction of the double bond of an array of alpha, beta-unsaturated aldehydes and ketones. It also reduces the nitro group of nitroester and nitroaromatic compounds. It could have a role in detoxification processes [H]

COG id: COG1902

COG function: function code C; NADH:flavin oxidoreductases, Old Yellow Enzyme family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NADH:flavin oxidoreductase/NADH oxidase family. NamA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789463, Length=332, Percent_Identity=27.4096385542169, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI1787939, Length=341, Percent_Identity=29.9120234604106, Blast_Score=108, Evalue=6e-25,
Organism=Caenorhabditis elegans, GI72001454, Length=248, Percent_Identity=29.4354838709677, Blast_Score=110, Evalue=2e-24,
Organism=Caenorhabditis elegans, GI17559802, Length=178, Percent_Identity=34.2696629213483, Blast_Score=107, Evalue=1e-23,
Organism=Caenorhabditis elegans, GI17564188, Length=179, Percent_Identity=33.5195530726257, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17559804, Length=179, Percent_Identity=33.5195530726257, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17540738, Length=201, Percent_Identity=32.8358208955224, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17565138, Length=198, Percent_Identity=29.7979797979798, Blast_Score=95, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17566914, Length=289, Percent_Identity=27.3356401384083, Blast_Score=88, Evalue=7e-18,
Organism=Saccharomyces cerevisiae, GI6325086, Length=234, Percent_Identity=29.4871794871795, Blast_Score=97, Evalue=5e-21,
Organism=Saccharomyces cerevisiae, GI6321973, Length=265, Percent_Identity=29.4339622641509, Blast_Score=94, Evalue=4e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR001155 [H]

Pfam domain/function: PF00724 Oxidored_FMN [H]

EC number: =1.6.99.1 [H]

Molecular weight: Translated: 40345; Mature: 40214

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAALLCIEATAV
CCCCCCCCEEECCCCCCEEEECHHHHHCCCCCCCCCEEEEEEHHHHHCCCEEEEEEEEEE
EPDGRITHGDLGLWDDATEAALKPVLAAIRRYSPIRVAMQLSHAGRKASSEVPWKGGQLV
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEE
PVAEGGWLPHAPSAVPHKDGETPPLALDAAGLNRVREAFAASAKRAARLGIDAIEVHAAH
EEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
GYLLHQFLSPLANRRTDEYGGSRENRMRFPLEIFDIVRAAFPEDRPVGVRVSATDWVEGG
HHHHHHHHHHHHHCCCHHCCCCCCCCEECCHHHHHHHHHHCCCCCCCEEEEECCHHHCCC
WELEDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRAVDMPTIAVG
CCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEE
LINEPAHANRLIEAGDADFVAMARAMLYDPRWPWHAAAELGAQVSAPPQYWRSQPREHKA
ECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHCCCHHHHH
LFGDIAFGQR
HHHHHCCCCC
>Mature Secondary Structure 
TALFSPFTLRGVTLPNRIVISPMCQYSAERGEATDWHMIHLGHLALSGAALLCIEATAV
CCCCCCCEEECCCCCCEEEECHHHHHCCCCCCCCCEEEEEEHHHHHCCCEEEEEEEEEE
EPDGRITHGDLGLWDDATEAALKPVLAAIRRYSPIRVAMQLSHAGRKASSEVPWKGGQLV
CCCCCEEECCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCCCCCCCCCCEEE
PVAEGGWLPHAPSAVPHKDGETPPLALDAAGLNRVREAFAASAKRAARLGIDAIEVHAAH
EEECCCCCCCCCCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHCCCCCEEEEHHH
GYLLHQFLSPLANRRTDEYGGSRENRMRFPLEIFDIVRAAFPEDRPVGVRVSATDWVEGG
HHHHHHHHHHHHHCCCHHCCCCCCCCEECCHHHHHHHHHHCCCCCCCEEEEECCHHHCCC
WELEDTIAFAHELKRRGCDWIDVSSGGVSPLQKIPLSPGYQVPFAQAVKRAVDMPTIAVG
CCHHHHHHHHHHHHHCCCCEEEECCCCCCHHHHCCCCCCCCCCHHHHHHHHHCCCEEEEE
LINEPAHANRLIEAGDADFVAMARAMLYDPRWPWHAAAELGAQVSAPPQYWRSQPREHKA
ECCCCHHHHHHHHCCCCHHHHHHHHHHCCCCCCHHHHHHHCCCCCCCHHHHHCCCHHHHH
LFGDIAFGQR
HHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA