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The map label for this gene is atpA [H]

Identifier: 161511082

GI number: 161511082

Start: 91137

End: 92864

Strand: Reverse

Name: atpA [H]

Synonym: BB0094

Alternate gene names: 161511082

Gene position: 92864-91137 (Counterclockwise)

Preceding gene: 15594441

Following gene: 15594439

Centisome position: 10.2

GC content: 34.95

Gene sequence:

>1728_bases
ATGAATACAAAAGGAAAAGTCGTTGGAGTTAATGGAAACTTAGTTACTATTGAGGTAGAAGGTTCAGTTTCTATGAATGA
AGTTTTATTTGTAAAGACTGCTGGTAGGAATTTAAAAGCAGAAGTAATTCGTATTAGGGGCAATGAAGTTGATGCACAGG
TTTTTGAATTGACAAAAGGGATATCTGTTGGAGACCTAGTTGAATTTACAGACAAACTTTTAACAGTTGAACTCGGACCA
GGGCTTTTAACTCAAGTATATGATGGGCTTCAAAATCCTTTGCCTGAATTGGCTATTCAATGTGGATTTTTTTTAGAAAG
GGGAGTATATTTAAGGCCCTTGAATAAAGATAAAAAGTGGAATTTTAAAAAAACCTCCAAAGTTGGAGATATCGTTATTG
CAGGAGATTTTTTAGGTTTTGTAATTGAGGGAACTGTTCACCATCAAATAATGATTCCATTTTATAAAAGGGATTCTTAT
AAAATTGTGGAGATTGTAAGTGATGGCGACTATTCGATTGATGAGCAAATTGCTGTAATTGAAGATGATTCTGGTATGAG
GCATAATATTACAATGTCTTTTCATTGGCCTGTTAAAGTTCCTATTACTAATTATAAGGAACGCCTTATTCCTAGTGAAC
CTATGTTGACTCAAACTAGAATTATAGATACATTTTTCCCAGTTGCCAAAGGTGGAACTTTTTGCATTCCGGGTCCTTTT
GGAGCAGGAAAAACGGTTCTTCAGCAGGTTACAAGTCGAAATGCTGATGTTGATGTAGTGATTATTGCAGCTTGTGGTGA
GCGAGCAGGAGAAGTGGTAGAAACTCTTAAAGAATTTCCCGAATTAATGGATCCAAAAACCGGCAAATCTTTAATGGACA
GGACTTGTATTATTTGTAATACATCTTCAATGCCAGTTGCAGCTAGAGAAGCTTCTGTTTATACTGCTATTACTATTGGT
GAGTATTACAGGCAAATGGGCCTTGATATTCTTCTTTTGGCAGATTCAACTTCAAGATGGGCTCAAGCAATGAGAGAAAT
GTCTGGACGCCTTGAGGAAATTCCTGGCGAGGAGGCTTTTCCGGCATATCTTGAGTCTGTTATTGCTTCCTTTTATGAAA
GGGCAGGTATTGTAGTTCTTAATAATGGGGATATTGGATCTGTAACAGTTGGTGGCTCTGTAAGTCCTGCTGGTGGTAAT
TTTGAAGAGCCAGTTACTCAAGCAACTTTAAAAGTTGTAGGAGCATTTCACGGGCTTACAAGAGAAAGGTCTGATGCTAG
GAAATTTCCAGCTATTAGTCCTCTTGAATCTTGGAGTAAATATAAAGGCGTTATTGATCAAAAAAAGACTGAATATGCAA
GATCTTTTTTGGTGAAAGGTAATGAAATTAATCAAATGATGAAAGTTGTTGGAGAAGAAGGCATAAGTAACGATGATTTT
TTAATTTATTTAAAATCCGAGCTACTTGATTCGTGCTATTTGCAGCAAAATTCATTTGATTCTATTGATGCTGCTGTTAG
TTCAGAGCGTCAAAATTATATGTTTGATATAGTTTATAACATTCTTAAAACTAACTTTGAGTTTTCTGATAAACTTCAAG
CAAGAGATTTTATAAATGAGTTAAGGCAAAATCTTTTAGACATGAATCTTTCTTCTTTTAAGGATCATAAGTTTAATAAA
TTGGAGCATGCTTTGGGTGAATTGATAAATTTTAAAAAGGTAATTTAG

Upstream 100 bases:

>100_bases
CATAATTTGTTTAAAGAAAAATTGGGTATTCAAAATTTTGACAATATTTGTAAAAATTTAATTGATAAAACTAATGAAAA
AGTTTAGAAAAGGAATTTAA

Downstream 100 bases:

>100_bases
GGGGTTTGGAGAAATATATATATGAAAAGAGTCTATAGTAAAATAGAGTCTATAGCAGGCAATGTAATAACTGTTACAGC
TCAAGGTATTAAGTATGGTG

Product: V-type ATP synthase subunit A

Products: NA

Alternate protein names: V-ATPase subunit A [H]

Number of amino acids: Translated: 575; Mature: 575

Protein sequence:

>575_residues
MNTKGKVVGVNGNLVTIEVEGSVSMNEVLFVKTAGRNLKAEVIRIRGNEVDAQVFELTKGISVGDLVEFTDKLLTVELGP
GLLTQVYDGLQNPLPELAIQCGFFLERGVYLRPLNKDKKWNFKKTSKVGDIVIAGDFLGFVIEGTVHHQIMIPFYKRDSY
KIVEIVSDGDYSIDEQIAVIEDDSGMRHNITMSFHWPVKVPITNYKERLIPSEPMLTQTRIIDTFFPVAKGGTFCIPGPF
GAGKTVLQQVTSRNADVDVVIIAACGERAGEVVETLKEFPELMDPKTGKSLMDRTCIICNTSSMPVAAREASVYTAITIG
EYYRQMGLDILLLADSTSRWAQAMREMSGRLEEIPGEEAFPAYLESVIASFYERAGIVVLNNGDIGSVTVGGSVSPAGGN
FEEPVTQATLKVVGAFHGLTRERSDARKFPAISPLESWSKYKGVIDQKKTEYARSFLVKGNEINQMMKVVGEEGISNDDF
LIYLKSELLDSCYLQQNSFDSIDAAVSSERQNYMFDIVYNILKTNFEFSDKLQARDFINELRQNLLDMNLSSFKDHKFNK
LEHALGELINFKKVI

Sequences:

>Translated_575_residues
MNTKGKVVGVNGNLVTIEVEGSVSMNEVLFVKTAGRNLKAEVIRIRGNEVDAQVFELTKGISVGDLVEFTDKLLTVELGP
GLLTQVYDGLQNPLPELAIQCGFFLERGVYLRPLNKDKKWNFKKTSKVGDIVIAGDFLGFVIEGTVHHQIMIPFYKRDSY
KIVEIVSDGDYSIDEQIAVIEDDSGMRHNITMSFHWPVKVPITNYKERLIPSEPMLTQTRIIDTFFPVAKGGTFCIPGPF
GAGKTVLQQVTSRNADVDVVIIAACGERAGEVVETLKEFPELMDPKTGKSLMDRTCIICNTSSMPVAAREASVYTAITIG
EYYRQMGLDILLLADSTSRWAQAMREMSGRLEEIPGEEAFPAYLESVIASFYERAGIVVLNNGDIGSVTVGGSVSPAGGN
FEEPVTQATLKVVGAFHGLTRERSDARKFPAISPLESWSKYKGVIDQKKTEYARSFLVKGNEINQMMKVVGEEGISNDDF
LIYLKSELLDSCYLQQNSFDSIDAAVSSERQNYMFDIVYNILKTNFEFSDKLQARDFINELRQNLLDMNLSSFKDHKFNK
LEHALGELINFKKVI
>Mature_575_residues
MNTKGKVVGVNGNLVTIEVEGSVSMNEVLFVKTAGRNLKAEVIRIRGNEVDAQVFELTKGISVGDLVEFTDKLLTVELGP
GLLTQVYDGLQNPLPELAIQCGFFLERGVYLRPLNKDKKWNFKKTSKVGDIVIAGDFLGFVIEGTVHHQIMIPFYKRDSY
KIVEIVSDGDYSIDEQIAVIEDDSGMRHNITMSFHWPVKVPITNYKERLIPSEPMLTQTRIIDTFFPVAKGGTFCIPGPF
GAGKTVLQQVTSRNADVDVVIIAACGERAGEVVETLKEFPELMDPKTGKSLMDRTCIICNTSSMPVAAREASVYTAITIG
EYYRQMGLDILLLADSTSRWAQAMREMSGRLEEIPGEEAFPAYLESVIASFYERAGIVVLNNGDIGSVTVGGSVSPAGGN
FEEPVTQATLKVVGAFHGLTRERSDARKFPAISPLESWSKYKGVIDQKKTEYARSFLVKGNEINQMMKVVGEEGISNDDF
LIYLKSELLDSCYLQQNSFDSIDAAVSSERQNYMFDIVYNILKTNFEFSDKLQARDFINELRQNLLDMNLSSFKDHKFNK
LEHALGELINFKKVI

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The V-type alpha chain is a catalytic subunit [H]

COG id: COG1155

COG function: function code C; Archaeal/vacuolar-type H+-ATPase subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI19913424, Length=522, Percent_Identity=40.0383141762452, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI19913428, Length=204, Percent_Identity=27.9411764705882, Blast_Score=80, Evalue=4e-15,
Organism=Homo sapiens, GI32189394, Length=306, Percent_Identity=25.4901960784314, Blast_Score=79, Evalue=1e-14,
Organism=Homo sapiens, GI19913426, Length=229, Percent_Identity=26.6375545851528, Blast_Score=74, Evalue=4e-13,
Organism=Escherichia coli, GI1790170, Length=449, Percent_Identity=22.271714922049, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1788251, Length=308, Percent_Identity=26.2987012987013, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1790172, Length=175, Percent_Identity=26.8571428571429, Blast_Score=69, Evalue=7e-13,
Organism=Caenorhabditis elegans, GI17565854, Length=520, Percent_Identity=38.0769230769231, Blast_Score=357, Evalue=1e-98,
Organism=Caenorhabditis elegans, GI25144756, Length=288, Percent_Identity=27.4305555555556, Blast_Score=83, Evalue=3e-16,
Organism=Caenorhabditis elegans, GI17510931, Length=306, Percent_Identity=27.4509803921569, Blast_Score=81, Evalue=1e-15,
Organism=Caenorhabditis elegans, GI17570191, Length=229, Percent_Identity=27.9475982532751, Blast_Score=79, Evalue=5e-15,
Organism=Caenorhabditis elegans, GI71988080, Length=178, Percent_Identity=28.0898876404494, Blast_Score=68, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI71988063, Length=178, Percent_Identity=28.0898876404494, Blast_Score=67, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI71988074, Length=178, Percent_Identity=28.0898876404494, Blast_Score=67, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6320016, Length=259, Percent_Identity=43.2432432432432, Blast_Score=215, Evalue=2e-56,
Organism=Saccharomyces cerevisiae, GI6322581, Length=325, Percent_Identity=25.2307692307692, Blast_Score=78, Evalue=3e-15,
Organism=Saccharomyces cerevisiae, GI6319603, Length=337, Percent_Identity=25.5192878338279, Blast_Score=78, Evalue=5e-15,
Organism=Drosophila melanogaster, GI20129479, Length=519, Percent_Identity=38.5356454720617, Blast_Score=362, Evalue=1e-100,
Organism=Drosophila melanogaster, GI24583988, Length=517, Percent_Identity=39.8452611218569, Blast_Score=360, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24583986, Length=517, Percent_Identity=39.8452611218569, Blast_Score=360, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24583984, Length=517, Percent_Identity=39.8452611218569, Blast_Score=360, Evalue=1e-99,
Organism=Drosophila melanogaster, GI24583992, Length=515, Percent_Identity=39.0291262135922, Blast_Score=358, Evalue=7e-99,
Organism=Drosophila melanogaster, GI24638766, Length=289, Percent_Identity=27.3356401384083, Blast_Score=82, Evalue=7e-16,
Organism=Drosophila melanogaster, GI281361666, Length=339, Percent_Identity=25.0737463126844, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24646341, Length=339, Percent_Identity=25.0737463126844, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI17136796, Length=339, Percent_Identity=25.0737463126844, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI28574560, Length=291, Percent_Identity=26.8041237113402, Blast_Score=79, Evalue=1e-14,

Paralogues:

None

Copy number: 10836 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 8,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000194
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100
- InterPro:   IPR022878 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 64034; Mature: 64034

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNTKGKVVGVNGNLVTIEVEGSVSMNEVLFVKTAGRNLKAEVIRIRGNEVDAQVFELTKG
CCCCCCEEEECCCEEEEEEECCCCCCEEEEEEECCCCCEEEEEEEECCCCHHHHHHHHCC
ISVGDLVEFTDKLLTVELGPGLLTQVYDGLQNPLPELAIQCGFFLERGVYLRPLNKDKKW
CCHHHHHHHHHCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCC
NFKKTSKVGDIVIAGDFLGFVIEGTVHHQIMIPFYKRDSYKIVEIVSDGDYSIDEQIAVI
CCCCCCCCCCEEEECCCEEEEEECEEEEEEEEEEEECCCEEEEEEEECCCCCCCCEEEEE
EDDSGMRHNITMSFHWPVKVPITNYKERLIPSEPMLTQTRIIDTFFPVAKGGTFCIPGPF
ECCCCCEEEEEEEEECEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCC
GAGKTVLQQVTSRNADVDVVIIAACGERAGEVVETLKEFPELMDPKTGKSLMDRTCIICN
CCHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHCCEEEEEC
TSSMPVAAREASVYTAITIGEYYRQMGLDILLLADSTSRWAQAMREMSGRLEEIPGEEAF
CCCCCCEECCCCEEEEEEHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCHHHHCCCCCCC
PAYLESVIASFYERAGIVVLNNGDIGSVTVGGSVSPAGGNFEEPVTQATLKVVGAFHGLT
HHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RERSDARKFPAISPLESWSKYKGVIDQKKTEYARSFLVKGNEINQMMKVVGEEGISNDDF
CCCHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCE
LIYLKSELLDSCYLQQNSFDSIDAAVSSERQNYMFDIVYNILKTNFEFSDKLQARDFINE
EEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LRQNLLDMNLSSFKDHKFNKLEHALGELINFKKVI
HHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNTKGKVVGVNGNLVTIEVEGSVSMNEVLFVKTAGRNLKAEVIRIRGNEVDAQVFELTKG
CCCCCCEEEECCCEEEEEEECCCCCCEEEEEEECCCCCEEEEEEEECCCCHHHHHHHHCC
ISVGDLVEFTDKLLTVELGPGLLTQVYDGLQNPLPELAIQCGFFLERGVYLRPLNKDKKW
CCHHHHHHHHHCEEEEEECCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEECCCCCCC
NFKKTSKVGDIVIAGDFLGFVIEGTVHHQIMIPFYKRDSYKIVEIVSDGDYSIDEQIAVI
CCCCCCCCCCEEEECCCEEEEEECEEEEEEEEEEEECCCEEEEEEEECCCCCCCCEEEEE
EDDSGMRHNITMSFHWPVKVPITNYKERLIPSEPMLTQTRIIDTFFPVAKGGTFCIPGPF
ECCCCCEEEEEEEEECEEEECCCCHHHHCCCCCCCHHHHHHHHHHHHHHCCCCEEECCCC
GAGKTVLQQVTSRNADVDVVIIAACGERAGEVVETLKEFPELMDPKTGKSLMDRTCIICN
CCHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHHHHHHCCCCCHHHHCCEEEEEC
TSSMPVAAREASVYTAITIGEYYRQMGLDILLLADSTSRWAQAMREMSGRLEEIPGEEAF
CCCCCCEECCCCEEEEEEHHHHHHHHCCEEEEEECCCHHHHHHHHHHHCHHHHCCCCCCC
PAYLESVIASFYERAGIVVLNNGDIGSVTVGGSVSPAGGNFEEPVTQATLKVVGAFHGLT
HHHHHHHHHHHHHCCCEEEEECCCCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHHHHH
RERSDARKFPAISPLESWSKYKGVIDQKKTEYARSFLVKGNEINQMMKVVGEEGISNDDF
CCCHHHHCCCCCCCHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCCE
LIYLKSELLDSCYLQQNSFDSIDAAVSSERQNYMFDIVYNILKTNFEFSDKLQARDFINE
EEEEHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHH
LRQNLLDMNLSSFKDHKFNKLEHALGELINFKKVI
HHHHHHHCCHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA