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The map label for this gene is pbp3 [H]

Identifier: 161509781

GI number: 161509781

Start: 1662330

End: 1664405

Strand: Reverse

Name: pbp3 [H]

Synonym: USA300HOU_1554

Alternate gene names: 161509781

Gene position: 1664405-1662330 (Counterclockwise)

Preceding gene: 161509782

Following gene: 161509780

Centisome position: 57.93

GC content: 33.48

Gene sequence:

>2076_bases
TTGTTAAAAAGACTAAAAGAAAAATCAAATGATGAAATCGTTCAAAATACAATTAACAAGAGAATTAACTTTATATTTGG
TGTGATTATATTTATTTTTGCAGTACTAGTACTACGTTTAGGTTATTTACAAATCGCACAAGGCTCACATTATAAACAAA
TTATAAAAAATGATGAAAACATTACAGTGAATGAGTCTGTGCCAAGAGGTCGTATTTTAGACAGAAATGGGAAAGTTTTA
GTTGATAATGCTTCTAAAATGGCTATTACATATACTAGGGGTCGAAAAACAACACAATCGGAAATGTTGGATACGGCTGA
AAAGTTATCAAAGCTAATCAAGATGGATACTAAGAAAATTACAGAACGTGATAAGAAAGATTTCTGGATTCAGTTGCATC
CTAAAAAAGCAAAAGCAATGATGACAAAAGAACAAGCTATGTTAGCAGATGGAAGTATTAAACAAGATCAATATGATAAA
CAACTGTTATCGAAAATCGGAAAATCACAATTAGATGAATTGTCTTCTAAAGATTTACAAGTTTTAGCTATTTTTCGAGA
GATGAATGCAGGAACAGTTTTAGATCCACAAATGATAAAAAATGAAGATGTCAGTGAAAAAGAGTATGCAGCAGTTTCTC
AGCAACTTTCCAAATTACCAGGTGTTAACACGTCTATGGATTGGGATAGAAAATATCCATATGGCGATACTTTAAGAGGT
ATATTCGGAGATGTATCGACACCTGCTGAAGGTATTCCAAAAGAATTGACAGAACATTACTTATCCAAAGGATATTCACG
CAATGATCGTGTTGGAAAATCTTACCTAGAATATCAATATGAAGATGTATTGCGTGGTAAGAAGAAAGAAATGAAATACA
CAACGGACAAATCTGGTAAAGTTACATCTTCAGAAGTGTTAAATCCTGGCGCTCGCGGTCAAGATTTGAAATTAACGATC
GATATAGATCTTCAAAAAGAAGTAGAAGCATTATTAGATAAACAAATTAAGAAGCTTCGCAGTCAAGGTGCCAAAGATAT
GGATAATGCAATGATGGTTGTACAAAATCCTAAAAATGGAGACATTCTTGCGCTTGCCGGAAAGCAGATTAATAAGAGTG
GTAAAATGACTGATTATGACATTGGTACGTTTACTTCTCAATTTGCGGTTGGATCTTCTGTAAAAGGTGGAACATTATTA
GCCGGTTATCAGAATAAAGCTATCAAAGTTGGAGAAACAATGGTCGATGAACCATTACATTTCCAAGGTGGTTTGACAAA
ACGATCATACTTCAATAAAAACGGGCATGTAACTATTAATGATAAGCAAGCTTTGATGCATTCATCAAACGTATATATGT
TTAAAACAGCATTAAAATTAGCGGGAGACCCTTATTATTCTGGTATGGCTTTACCTTCAGACATAAGTTCACCTGCCCAA
AAGCTAAGAAGAGGATTAAATCAAGTAGGCTTAGGTGTGAAAACAGGGATAGATTTACCAAATGAAACAAGAGGTCAAAT
CGAACCATTAACAAATAATCCAGGTAATTATCTAGATTTATCAATTGGTCAATATGATACCTATACACCATTACAATTAT
CACAATATGTTTCAACTATAGCGAATGATGGTTATAGAATACAGCCACACATTGGATTAACGATTCATGAATCAACTAAT
AAAGATGAGGTTGGTCCACTCAAGAAGAAAATTAATGGCACTGTCTTGAACAAGGTTAATAATACTGAAAAGGAAATCAA
ACAAATTCAAGAAGGATTCAAAATGGCATTTAATGATAAAGATGGTACTGGATATGTTAGTTTTAAAGATACAGTAGTAC
CTACTGCTGGTAAAACGGGTACCGCAGAAGTGTTCCAAAACGGAGAGCCAAGAGTTAACTCTACTTATATAGGATACGCG
CCAATTGATGATCCAAAATTAGCGTTTTCAATTGTATATACAAATCAGCCTGTACCACCACCATGGTTAACAGGTGGAGA
CTTAGGTAGAGATGTAATTAACTACTACTTTAAGCAGTTAGGTAAAAATGATAAAAATAAAGACAAAGACAAATAA

Upstream 100 bases:

>100_bases
CTCTTAAATGAGACCGTTATTTTTTTGTCAAAAAGATAGAAATAATTTCTAAATTCATATATGATTTAAAGTGAAAGACT
TTGAATAGAGGTAGGTAGTT

Downstream 100 bases:

>100_bases
AATTTAACCTGACGATTGTGTAGCGCATGGTTGTAAAATTTTAACTTTGCAAATATTATAGATGTTGGTATAATAATAAA
GTCGTATTTAGAAATGATAA

Product: penicillin-binding protein 3

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 691; Mature: 691

Protein sequence:

>691_residues
MLKRLKEKSNDEIVQNTINKRINFIFGVIIFIFAVLVLRLGYLQIAQGSHYKQIIKNDENITVNESVPRGRILDRNGKVL
VDNASKMAITYTRGRKTTQSEMLDTAEKLSKLIKMDTKKITERDKKDFWIQLHPKKAKAMMTKEQAMLADGSIKQDQYDK
QLLSKIGKSQLDELSSKDLQVLAIFREMNAGTVLDPQMIKNEDVSEKEYAAVSQQLSKLPGVNTSMDWDRKYPYGDTLRG
IFGDVSTPAEGIPKELTEHYLSKGYSRNDRVGKSYLEYQYEDVLRGKKKEMKYTTDKSGKVTSSEVLNPGARGQDLKLTI
DIDLQKEVEALLDKQIKKLRSQGAKDMDNAMMVVQNPKNGDILALAGKQINKSGKMTDYDIGTFTSQFAVGSSVKGGTLL
AGYQNKAIKVGETMVDEPLHFQGGLTKRSYFNKNGHVTINDKQALMHSSNVYMFKTALKLAGDPYYSGMALPSDISSPAQ
KLRRGLNQVGLGVKTGIDLPNETRGQIEPLTNNPGNYLDLSIGQYDTYTPLQLSQYVSTIANDGYRIQPHIGLTIHESTN
KDEVGPLKKKINGTVLNKVNNTEKEIKQIQEGFKMAFNDKDGTGYVSFKDTVVPTAGKTGTAEVFQNGEPRVNSTYIGYA
PIDDPKLAFSIVYTNQPVPPPWLTGGDLGRDVINYYFKQLGKNDKNKDKDK

Sequences:

>Translated_691_residues
MLKRLKEKSNDEIVQNTINKRINFIFGVIIFIFAVLVLRLGYLQIAQGSHYKQIIKNDENITVNESVPRGRILDRNGKVL
VDNASKMAITYTRGRKTTQSEMLDTAEKLSKLIKMDTKKITERDKKDFWIQLHPKKAKAMMTKEQAMLADGSIKQDQYDK
QLLSKIGKSQLDELSSKDLQVLAIFREMNAGTVLDPQMIKNEDVSEKEYAAVSQQLSKLPGVNTSMDWDRKYPYGDTLRG
IFGDVSTPAEGIPKELTEHYLSKGYSRNDRVGKSYLEYQYEDVLRGKKKEMKYTTDKSGKVTSSEVLNPGARGQDLKLTI
DIDLQKEVEALLDKQIKKLRSQGAKDMDNAMMVVQNPKNGDILALAGKQINKSGKMTDYDIGTFTSQFAVGSSVKGGTLL
AGYQNKAIKVGETMVDEPLHFQGGLTKRSYFNKNGHVTINDKQALMHSSNVYMFKTALKLAGDPYYSGMALPSDISSPAQ
KLRRGLNQVGLGVKTGIDLPNETRGQIEPLTNNPGNYLDLSIGQYDTYTPLQLSQYVSTIANDGYRIQPHIGLTIHESTN
KDEVGPLKKKINGTVLNKVNNTEKEIKQIQEGFKMAFNDKDGTGYVSFKDTVVPTAGKTGTAEVFQNGEPRVNSTYIGYA
PIDDPKLAFSIVYTNQPVPPPWLTGGDLGRDVINYYFKQLGKNDKNKDKDK
>Mature_691_residues
MLKRLKEKSNDEIVQNTINKRINFIFGVIIFIFAVLVLRLGYLQIAQGSHYKQIIKNDENITVNESVPRGRILDRNGKVL
VDNASKMAITYTRGRKTTQSEMLDTAEKLSKLIKMDTKKITERDKKDFWIQLHPKKAKAMMTKEQAMLADGSIKQDQYDK
QLLSKIGKSQLDELSSKDLQVLAIFREMNAGTVLDPQMIKNEDVSEKEYAAVSQQLSKLPGVNTSMDWDRKYPYGDTLRG
IFGDVSTPAEGIPKELTEHYLSKGYSRNDRVGKSYLEYQYEDVLRGKKKEMKYTTDKSGKVTSSEVLNPGARGQDLKLTI
DIDLQKEVEALLDKQIKKLRSQGAKDMDNAMMVVQNPKNGDILALAGKQINKSGKMTDYDIGTFTSQFAVGSSVKGGTLL
AGYQNKAIKVGETMVDEPLHFQGGLTKRSYFNKNGHVTINDKQALMHSSNVYMFKTALKLAGDPYYSGMALPSDISSPAQ
KLRRGLNQVGLGVKTGIDLPNETRGQIEPLTNNPGNYLDLSIGQYDTYTPLQLSQYVSTIANDGYRIQPHIGLTIHESTN
KDEVGPLKKKINGTVLNKVNNTEKEIKQIQEGFKMAFNDKDGTGYVSFKDTVVPTAGKTGTAEVFQNGEPRVNSTYIGYA
PIDDPKLAFSIVYTNQPVPPPWLTGGDLGRDVINYYFKQLGKNDKNKDKDK

Specific function: Cell Wall Formation; Pbp-2 Is Responsible For The Determination Of The Rod Shape Of The Cell. Its Synthesize Cross- Linked Peptidoglycan From The Lipid Intermediates. [C]

COG id: COG0768

COG function: function code M; Cell division protein FtsI/penicillin-binding protein 2

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the transpeptidase family [H]

Homologues:

Organism=Escherichia coli, GI1786854, Length=559, Percent_Identity=23.0769230769231, Blast_Score=99, Evalue=9e-22,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012338
- InterPro:   IPR005311
- InterPro:   IPR001460 [H]

Pfam domain/function: PF03717 PBP_dimer; PF00905 Transpeptidase [H]

EC number: NA

Molecular weight: Translated: 77252; Mature: 77252

Theoretical pI: Translated: 9.77; Mature: 9.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKRLKEKSNDEIVQNTINKRINFIFGVIIFIFAVLVLRLGYLQIAQGSHYKQIIKNDEN
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHCCCCC
ITVNESVPRGRILDRNGKVLVDNASKMAITYTRGRKTTQSEMLDTAEKLSKLIKMDTKKI
EEEECCCCCCCEECCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
TERDKKDFWIQLHPKKAKAMMTKEQAMLADGSIKQDQYDKQLLSKIGKSQLDELSSKDLQ
HHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCHH
VLAIFREMNAGTVLDPQMIKNEDVSEKEYAAVSQQLSKLPGVNTSMDWDRKYPYGDTLRG
HHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
IFGDVSTPAEGIPKELTEHYLSKGYSRNDRVGKSYLEYQYEDVLRGKKKEMKYTTDKSGK
HHCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
VTSSEVLNPGARGQDLKLTIDIDLQKEVEALLDKQIKKLRSQGAKDMDNAMMVVQNPKNG
CCHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCC
DILALAGKQINKSGKMTDYDIGTFTSQFAVGSSVKGGTLLAGYQNKAIKVGETMVDEPLH
CEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCEEECCHHHCCCCC
FQGGLTKRSYFNKNGHVTINDKQALMHSSNVYMFKTALKLAGDPYYSGMALPSDISSPAQ
CCCCCCHHHHCCCCCCEEECCHHHHHHCCCEEEEEHHHHHCCCCCCCCCCCCCCCCHHHH
KLRRGLNQVGLGVKTGIDLPNETRGQIEPLTNNPGNYLDLSIGQYDTYTPLQLSQYVSTI
HHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
ANDGYRIQPHIGLTIHESTNKDEVGPLKKKINGTVLNKVNNTEKEIKQIQEGFKMAFNDK
HCCCEEECCEEEEEEECCCCCCCCCHHHHHHCCHHHHCCCCHHHHHHHHHHHHHEEECCC
DGTGYVSFKDTVVPTAGKTGTAEVFQNGEPRVNSTYIGYAPIDDPKLAFSIVYTNQPVPP
CCCEEEEEECCEECCCCCCCCHHHHCCCCCCCCCEEEEECCCCCCCEEEEEEEECCCCCC
PWLTGGDLGRDVINYYFKQLGKNDKNKDKDK
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MLKRLKEKSNDEIVQNTINKRINFIFGVIIFIFAVLVLRLGYLQIAQGSHYKQIIKNDEN
CCCHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCHHHCCCCCHHHHHHCCCCC
ITVNESVPRGRILDRNGKVLVDNASKMAITYTRGRKTTQSEMLDTAEKLSKLIKMDTKKI
EEEECCCCCCCEECCCCCEEEECCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHH
TERDKKDFWIQLHPKKAKAMMTKEQAMLADGSIKQDQYDKQLLSKIGKSQLDELSSKDLQ
HHCCCCCEEEEECCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHCHHHHHHHCCCCHH
VLAIFREMNAGTVLDPQMIKNEDVSEKEYAAVSQQLSKLPGVNTSMDWDRKYPYGDTLRG
HHHHHHHCCCCCCCCHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHH
IFGDVSTPAEGIPKELTEHYLSKGYSRNDRVGKSYLEYQYEDVLRGKKKEMKYTTDKSGK
HHCCCCCCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCHHHCCCCCCCCCC
VTSSEVLNPGARGQDLKLTIDIDLQKEVEALLDKQIKKLRSQGAKDMDNAMMVVQNPKNG
CCHHHHCCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEECCCCC
DILALAGKQINKSGKMTDYDIGTFTSQFAVGSSVKGGTLLAGYQNKAIKVGETMVDEPLH
CEEEEECCCCCCCCCCCCCCCCHHHHHHHCCCCCCCCEEEECCCCCCEEECCHHHCCCCC
FQGGLTKRSYFNKNGHVTINDKQALMHSSNVYMFKTALKLAGDPYYSGMALPSDISSPAQ
CCCCCCHHHHCCCCCCEEECCHHHHHHCCCEEEEEHHHHHCCCCCCCCCCCCCCCCHHHH
KLRRGLNQVGLGVKTGIDLPNETRGQIEPLTNNPGNYLDLSIGQYDTYTPLQLSQYVSTI
HHHHHHHHHCCCCCCCCCCCCCCCCCEECCCCCCCCEEEEECCCCCCCCHHHHHHHHHHH
ANDGYRIQPHIGLTIHESTNKDEVGPLKKKINGTVLNKVNNTEKEIKQIQEGFKMAFNDK
HCCCEEECCEEEEEEECCCCCCCCCHHHHHHCCHHHHCCCCHHHHHHHHHHHHHEEECCC
DGTGYVSFKDTVVPTAGKTGTAEVFQNGEPRVNSTYIGYAPIDDPKLAFSIVYTNQPVPP
CCCEEEEEECCEECCCCCCCCHHHHCCCCCCCCCEEEEECCCCCCCEEEEEEEECCCCCC
PWLTGGDLGRDVINYYFKQLGKNDKNKDKDK
CCCCCCHHHHHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]