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The map label for this gene is spa [H]

Identifier: 161508379

GI number: 161508379

Start: 128109

End: 129623

Strand: Reverse

Name: spa [H]

Synonym: USA300HOU_0122

Alternate gene names: 161508379

Gene position: 129623-128109 (Counterclockwise)

Preceding gene: 161508380

Following gene: 161508375

Centisome position: 4.51

GC content: 37.89

Gene sequence:

>1515_bases
ATGATGACTTTACAAATACATACAGGGGGTATTAATTTGAAAAAGAAAAACATTTATTCAATTCGTAAACTAGGTGTAGG
TATTGCATCTGTAACTTTAGGTACATTACTTATATCTGGTGGCGTAACACCTGCTGCAAATGCTGCGCAACACGATGAAG
CTCAACAAAATGCTTTTTATCAAGTCTTAAATATGCCTAACTTAAATGCTGATCAACGCAATGGTTTTATCCAAAGCCTT
AAAGATGATCCAAGCCAAAGTGCTAACGTTTTAGGTGAAGCTCAAAAACTTAATGACTCTCAAGCTCCAAAAGCTGATGC
GCAACAAAATAACTTCAACAAAGATCAACAAAGCGCCTTCTATGAAATCTTGAACATGCCTAACTTAAACGAAGCGCAAC
GTAACGGCTTCATTCAAAGTCTTAAAGACGACCCAAGCCAAAGCACTAACGTTTTAGGTGAAGCTAAAAAATTAAACGAA
TCTCAAGCACCGAAAGCTGATAACAATTTCAACAAAGAACAACAAAATGCTTTCTATGAAATCTTGAATATGCCTAACTT
AAACGAAGAACAACGCAATGGTTTCATCCAAAGCTTAAAAGATGACCCAAGCCAAAGTGCTAACCTATTGTCAGAAGCTA
AAAAGTTAAATGAATCTCAAGCACCGAAAGCGGATAACAAATTCAACAAAGAACAACAAAATGCTTTCTATGAAATCTTA
CATTTACCTAACTTAAACGAAGAACAACGCAATGGTTTCATCCAAAGCCTAAAAGATGACCCAAGCCAAAGCGCTAACCT
TTTAGCAGAAGCTAAAAAGCTAAATGATGCTCAAGCACCAAAAGCTGACAACAAATTCAACAAAGAACAACAAAATGCTT
TCTATGAAATTTTACATTTACCTAACTTAACTGAAGAACAACGTAACGGCTTCATCCAAAGCCTTAAAGACGATCCTTCA
GTGAGCAAAGAAATTTTAGCAGAAGCTAAAAAGCTAAACGATGCTCAAGCACCAAAAGAGGAAGACAATAACAAGCCTGG
CAAAGAAGACAATAACAAGCCTGGCAAAGAAGACAACAACAAGCCTGGTAAAGAAGACAACAACAAGCCTGGCAAAGAAG
ACGGCAACAAGCCTGGTAAAGAAGACAACAAAAAACCTGGTAAAGAAGACGGCAACAAGCCTGGCAAAGAAGATGGCAAC
AAACCTGGTAAAGAAGATGGTAACGGAGTACATGTCGTTAAACCTGGTGATACAGTAAATGACATTGCAAAAGCAAACGG
CACTACTGCTGACAAAATTGCTGCAGATAACAAATTAGCTGATAAAAACATGATCAAACCTGGTCAAGAACTTGTTGTTG
ATAAGAAGCAACCAGCAAACCATGCAGATGCTAACAAAGCTCAAGCATTACCAGAAACTGGTGAAGAAAATCCATTCATC
GGTACAACTGTATTTGGTGGATTATCATTAGCCTTAGGTGCAGCGTTATTAGCTGGACGTCGTCGCGAACTATAA

Upstream 100 bases:

>100_bases
AATCTTTCAGCAAAATATTTATTTTATAAGTTGTAAAACTTACCTTTAAATTTAATTATAAATATAGATTTTAGTATTGC
AATACATAATTCGTTATATT

Downstream 100 bases:

>100_bases
AAACAAACAATACACAACGATAGATATCATTTTATCCAAACCAATTTTAACTTATATACGTTGATTAACACATTCTTATT
TGAAATGATAAGAATCATCT

Product: immunoglobulin G binding protein A

Products: NA

Alternate protein names: IgG-binding protein A; Staphylococcal protein A [H]

Number of amino acids: Translated: 504; Mature: 504

Protein sequence:

>504_residues
MMTLQIHTGGINLKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFYQVLNMPNLNADQRNGFIQSL
KDDPSQSANVLGEAQKLNDSQAPKADAQQNNFNKDQQSAFYEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNE
SQAPKADNNFNKEQQNAFYEILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNKEQQNAFYEIL
HLPNLNEEQRNGFIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNKEQQNAFYEILHLPNLTEEQRNGFIQSLKDDPS
VSKEILAEAKKLNDAQAPKEEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDGN
KPGKEDGNGVHVVKPGDTVNDIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQALPETGEENPFI
GTTVFGGLSLALGAALLAGRRREL

Sequences:

>Translated_504_residues
MMTLQIHTGGINLKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFYQVLNMPNLNADQRNGFIQSL
KDDPSQSANVLGEAQKLNDSQAPKADAQQNNFNKDQQSAFYEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNE
SQAPKADNNFNKEQQNAFYEILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNKEQQNAFYEIL
HLPNLNEEQRNGFIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNKEQQNAFYEILHLPNLTEEQRNGFIQSLKDDPS
VSKEILAEAKKLNDAQAPKEEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDGN
KPGKEDGNGVHVVKPGDTVNDIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQALPETGEENPFI
GTTVFGGLSLALGAALLAGRRREL
>Mature_504_residues
MMTLQIHTGGINLKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFYQVLNMPNLNADQRNGFIQSL
KDDPSQSANVLGEAQKLNDSQAPKADAQQNNFNKDQQSAFYEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNE
SQAPKADNNFNKEQQNAFYEILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNKEQQNAFYEIL
HLPNLNEEQRNGFIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNKEQQNAFYEILHLPNLTEEQRNGFIQSLKDDPS
VSKEILAEAKKLNDAQAPKEEDNNKPGKEDNNKPGKEDNNKPGKEDNNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDGN
KPGKEDGNGVHVVKPGDTVNDIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQALPETGEENPFI
GTTVFGGLSLALGAALLAGRRREL

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Secreted, cell wall; Peptidoglycan-anchor (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 LysM repeat [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005877
- InterPro:   IPR019948
- InterPro:   IPR009063
- InterPro:   IPR019931
- InterPro:   IPR005038
- InterPro:   IPR018392
- InterPro:   IPR002482
- InterPro:   IPR003132
- InterPro:   IPR001899 [H]

Pfam domain/function: PF02216 B; PF00746 Gram_pos_anchor; PF01476 LysM; PF03373 Octapeptide; PF04650 YSIRK_signal [H]

EC number: NA

Molecular weight: Translated: 55111; Mature: 55111

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: PS50847 GRAM_POS_ANCHORING

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.2 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MMTLQIHTGGINLKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFY
CEEEEEECCCCEEEHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
QVLNMPNLNADQRNGFIQSLKDDPSQSANVLGEAQKLNDSQAPKADAQQNNFNKDQQSAF
HHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHH
YEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNESQAPKADNNFNKEQQNAFYE
HHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHH
ILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNKEQQNAFYEIL
HHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHCCCCCCCCCCHHHHHHHHHHH
HLPNLNEEQRNGFIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNKEQQNAFYEILHL
HCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHCCCCCCCCCCHHHHHHHHHHHHC
PNLTEEQRNGFIQSLKDDPSVSKEILAEAKKLNDAQAPKEEDNNKPGKEDNNKPGKEDNN
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHCCCCHHCCCCCCCCCCCCCCCCCCC
KPGKEDNNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDGNKPGKEDGNGVHVVKPGDTVN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHH
DIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQALPETGEENPFI
HHHHCCCCCHHHHHCCCCHHHHHHCCCCHHHEECCCCCCCCCCCHHHHCCCCCCCCCCEE
GTTVFGGLSLALGAALLAGRRREL
HHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MMTLQIHTGGINLKKKNIYSIRKLGVGIASVTLGTLLISGGVTPAANAAQHDEAQQNAFY
CEEEEEECCCCEEEHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHH
QVLNMPNLNADQRNGFIQSLKDDPSQSANVLGEAQKLNDSQAPKADAQQNNFNKDQQSAF
HHHCCCCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCCCCCHHCCCCHHHHHHH
YEILNMPNLNEAQRNGFIQSLKDDPSQSTNVLGEAKKLNESQAPKADNNFNKEQQNAFYE
HHHHCCCCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHCCHHCCCCCCCCCCHHHHHHHHH
ILNMPNLNEEQRNGFIQSLKDDPSQSANLLSEAKKLNESQAPKADNKFNKEQQNAFYEIL
HHCCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHCCCCCCCCCCHHHHHHHHHHH
HLPNLNEEQRNGFIQSLKDDPSQSANLLAEAKKLNDAQAPKADNKFNKEQQNAFYEILHL
HCCCCCHHHHHHHHHHHHCCHHHHHHHHHHHHHHCHHCCCCCCCCCCHHHHHHHHHHHHC
PNLTEEQRNGFIQSLKDDPSVSKEILAEAKKLNDAQAPKEEDNNKPGKEDNNKPGKEDNN
CCCCHHHHHHHHHHHCCCCCHHHHHHHHHHHHCHHCCCCHHCCCCCCCCCCCCCCCCCCC
KPGKEDNNKPGKEDGNKPGKEDNKKPGKEDGNKPGKEDGNKPGKEDGNGVHVVKPGDTVN
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEECCCCHHH
DIAKANGTTADKIAADNKLADKNMIKPGQELVVDKKQPANHADANKAQALPETGEENPFI
HHHHCCCCCHHHHHCCCCHHHHHHCCCCHHHEECCCCCCCCCCCHHHHCCCCCCCCCCEE
GTTVFGGLSLALGAALLAGRRREL
HHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 6319407; 6338496 [H]