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The map label for this gene is insK [H]

Identifier: 161508319

GI number: 161508319

Start: 61724

End: 62533

Strand: Reverse

Name: insK [H]

Synonym: USA300HOU_0055

Alternate gene names: 161508319

Gene position: 62533-61724 (Counterclockwise)

Preceding gene: 161508321

Following gene: 161508317

Centisome position: 2.18

GC content: 31.85

Gene sequence:

>810_bases
ATGAAAAGAGCTTCTTATTCAGTAGAAACAAAGTATAAAGCAGTTGAAATGAAAGCAGCAGGATTTCCAACAAAAGAAAT
TATGAAAGAATTAAATATTAGAAATAGAACACAAGTGAAAAATTGGTGGCGATGGTATCGAAATGGGGAAAGTTATAGAT
TTTCACAACATGTTGGTAAACAATATACCTACGGTTATCGTAAGATTACAGCATTGATTAATCAATGTTATACATCACCA
ATTAATCATAAGAGAGTACAGAGAGTGATGCAGAAGCATCATTTGAACTGCCGAGTTAGACCTAAAAAGACGACAAGAAT
AGGTAAACCGTATTATAAAACGGACAATTTATTACAAAGACAATTTAAAGCGAGTTGTCCCATGGAAGTATTAACAACCG
ATATTACTTATTTACCATTTGGTCATTCTATGTTGTATTTATCTTCGATAATGGACATTTATAACGGAGAAATTGTGGCG
TATAAAATAGATGATAAACAAGACCAACGTTTAGTTAATGATACATTAAATCAAATCGATATACCTGAGGGGTGTATATT
ACATAGTGATCAAGGCAGCGTTTATACATCTTATGCTTATTATCAATTATGCGAAGAAAAAGGCATTATCAGAAGTATGT
CCCGAAAGGGAACACCTGCCGATAACGCCCCGATAGAAAGTTTCCATTCCTCGCTAAAGTCTGAAACTTTTTACATCAAT
AATCAGCTTAATAACTCTAATCATATTGTAATAGATATTGTCGAAAATACATTAAAAACTATAATAATAATCGAATTCAA
CAAAAACTAG

Upstream 100 bases:

>100_bases
ATCAATTTTAATTTTAGACTGACCCCAATAGTGGGAATTATATAAAAACACTTTCGTTGAATTCATATTAAAATGAATCA
TACGGAGGTGTTTTTTTTCT

Downstream 100 bases:

>100_bases
GCTACTTATCCCCTGTAAAATACAGAGAATTAGCAGCCTAGAACATAGTGTTTTTATTAAGTTCCCATTTTAAGGGTTCA
GTGCCTCTAACAAAAAGCAT

Product: integrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 269; Mature: 269

Protein sequence:

>269_residues
MKRASYSVETKYKAVEMKAAGFPTKEIMKELNIRNRTQVKNWWRWYRNGESYRFSQHVGKQYTYGYRKITALINQCYTSP
INHKRVQRVMQKHHLNCRVRPKKTTRIGKPYYKTDNLLQRQFKASCPMEVLTTDITYLPFGHSMLYLSSIMDIYNGEIVA
YKIDDKQDQRLVNDTLNQIDIPEGCILHSDQGSVYTSYAYYQLCEEKGIIRSMSRKGTPADNAPIESFHSSLKSETFYIN
NQLNNSNHIVIDIVENTLKTIIIIEFNKN

Sequences:

>Translated_269_residues
MKRASYSVETKYKAVEMKAAGFPTKEIMKELNIRNRTQVKNWWRWYRNGESYRFSQHVGKQYTYGYRKITALINQCYTSP
INHKRVQRVMQKHHLNCRVRPKKTTRIGKPYYKTDNLLQRQFKASCPMEVLTTDITYLPFGHSMLYLSSIMDIYNGEIVA
YKIDDKQDQRLVNDTLNQIDIPEGCILHSDQGSVYTSYAYYQLCEEKGIIRSMSRKGTPADNAPIESFHSSLKSETFYIN
NQLNNSNHIVIDIVENTLKTIIIIEFNKN
>Mature_269_residues
MKRASYSVETKYKAVEMKAAGFPTKEIMKELNIRNRTQVKNWWRWYRNGESYRFSQHVGKQYTYGYRKITALINQCYTSP
INHKRVQRVMQKHHLNCRVRPKKTTRIGKPYYKTDNLLQRQFKASCPMEVLTTDITYLPFGHSMLYLSSIMDIYNGEIVA
YKIDDKQDQRLVNDTLNQIDIPEGCILHSDQGSVYTSYAYYQLCEEKGIIRSMSRKGTPADNAPIESFHSSLKSETFYIN
NQLNNSNHIVIDIVENTLKTIIIIEFNKN

Specific function: Involved in the transposition of the insertion sequence IS150 [H]

COG id: COG2801

COG function: function code L; Transposase and inactivated derivatives

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Contains 1 integrase catalytic domain [H]

Homologues:

Organism=Homo sapiens, GI310129419, Length=181, Percent_Identity=29.2817679558011, Blast_Score=73, Evalue=3e-13,
Organism=Escherichia coli, GI1789981, Length=182, Percent_Identity=37.3626373626374, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI1788405, Length=282, Percent_Identity=27.3049645390071, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1787263, Length=282, Percent_Identity=27.3049645390071, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786753, Length=282, Percent_Identity=27.3049645390071, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786570, Length=282, Percent_Identity=27.3049645390071, Blast_Score=82, Evalue=4e-17,
Organism=Escherichia coli, GI1786490, Length=282, Percent_Identity=27.3049645390071, Blast_Score=82, Evalue=4e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001584
- InterPro:   IPR012337 [H]

Pfam domain/function: PF00665 rve [H]

EC number: NA

Molecular weight: Translated: 31582; Mature: 31582

Theoretical pI: Translated: 9.79; Mature: 9.79

Prosite motif: PS50994 INTEGRASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRASYSVETKYKAVEMKAAGFPTKEIMKELNIRNRTQVKNWWRWYRNGESYRFSQHVGK
CCCCCCCHHHHHEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEHHHHHCC
QYTYGYRKITALINQCYTSPINHKRVQRVMQKHHLNCRVRPKKTTRIGKPYYKTDNLLQR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHH
QFKASCPMEVLTTDITYLPFGHSMLYLSSIMDIYNGEIVAYKIDDKQDQRLVNDTLNQID
HHHCCCCHHHHHCCCEECCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCC
IPEGCILHSDQGSVYTSYAYYQLCEEKGIIRSMSRKGTPADNAPIESFHSSLKSETFYIN
CCCCEEEECCCCCEEEHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEE
NQLNNSNHIVIDIVENTLKTIIIIEFNKN
CCCCCCCCEEEEEECCCCEEEEEEEECCC
>Mature Secondary Structure
MKRASYSVETKYKAVEMKAAGFPTKEIMKELNIRNRTQVKNWWRWYRNGESYRFSQHVGK
CCCCCCCHHHHHEEEEEECCCCCHHHHHHHCCCCCHHHHHHHHHHHHCCCCEEHHHHHCC
QYTYGYRKITALINQCYTSPINHKRVQRVMQKHHLNCRVRPKKTTRIGKPYYKTDNLLQR
HHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCEEECCCCCCCCCCCCHHHHHHHHH
QFKASCPMEVLTTDITYLPFGHSMLYLSSIMDIYNGEIVAYKIDDKQDQRLVNDTLNQID
HHHCCCCHHHHHCCCEECCCCHHHHHHHHHHHHHCCCEEEEEECCHHHHHHHHHHHHHCC
IPEGCILHSDQGSVYTSYAYYQLCEEKGIIRSMSRKGTPADNAPIESFHSSLKSETFYIN
CCCCEEEECCCCCEEEHHHHHHHHHHCCHHHHHHCCCCCCCCCCHHHHHHHHCCCEEEEE
NQLNNSNHIVIDIVENTLKTIIIIEFNKN
CCCCCCCCEEEEEECCCCEEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2841644; 2541046; 8041620; 9278503 [H]