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The map label for this gene is yrkH [H]

Identifier: 161508310

GI number: 161508310

Start: 55177

End: 56181

Strand: Reverse

Name: yrkH [H]

Synonym: USA300HOU_0045

Alternate gene names: 161508310

Gene position: 56181-55177 (Counterclockwise)

Preceding gene: 161508313

Following gene: 161508307

Centisome position: 1.96

GC content: 33.73

Gene sequence:

>1005_bases
ATGATCATTGATCCTATTTGTGACTTATCTTCATATATTCGAGTTGCCGATGAAGAGAGTTTAACCATTACTCATGCAGC
TGAAACACATATACATGCAAATTTTGTTTCAGGAATTAGAGATGTTGCTATAAAGTTAAATGCTAGTATTTATGTATCGG
GCGAAAGTGATGACATGTTAGGTTATAAAAATATGCCTAACCACACTCATTTTGTTCAACATAATGATGATATTTATGTA
GGAAATATAAAATTAAAAGTGCTTCATACACCTGGTCACACGCCAGAAAGTATAAGTTTTTTACTTACTGACGAAGGTGC
TGGAGCACAAGTTCCAATGGGACTATTCAGTGGTGATTTTATTTTTGTAGGAGATATCGGTAGACCTGATTTACTAGAAA
AAGCTGTTAAAGTAGAAGGATTATCTGAAATAGGCGCAAAACAAATGTTTAAATCTATTGAAAGTATTAAAGACTTGCCA
GACTACATTCAAATTTGGCCTGGTCATGGCGCTGGTAGTCCTTGTGGTAAATCTTTAGGTGCTATTCCAACATCTACGCT
TGGCTATGAAAAACAAACGAACTGGGCTTTTTCTGAAAATAATGAAGCTACCTTTATCGATAAACTCATTTCTGACCAAC
CTGCACCACCACATCATTTTGCACAAATGAAAAAAATTAATCAATTCGGTATGAATTTATATCAACCTTATACGGTTTAT
CCAGCTACAAGTACAAACAGATTAACTTTTGATCTCCGCAGTAAGGAGGCTTATCATGGTGGACATATTGAAGGTACAAT
CAATATTCCATATGATAAAAATTTCATCAATCAAATTGGCTGGTATCTAAACTATAATCAAGAAATTAACTTGATTGGAG
ACTATCACCTTGTTTCAAAAGCAACACATAACATACTTTACAACTTATTGGATATGATAATGTGTCTGGATATCAGTTAC
CACAAGCTCAAATTCAAACACAATCTGTTCATAGTAAAGACATAA

Upstream 100 bases:

>100_bases
ATAATTATCACCCTTGATAACAAATTGACTATCATCAATTTATGATAAACATTTATCTCAAGCATCTTATTTAATCGGTT
GTCAAAAAACTGGAGAAGCC

Downstream 100 bases:

>100_bases
CTGGTAATGAAGCACATGTCTTAGATGTACGTAATGATAATGAATGGAATAATGGCCACTTATCCCAAGCGGTTCATGTG
CCACACGGCAAACTTTTAGA

Product: beta-lactamase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 334; Mature: 334

Protein sequence:

>334_residues
MIIDPICDLSSYIRVADEESLTITHAAETHIHANFVSGIRDVAIKLNASIYVSGESDDMLGYKNMPNHTHFVQHNDDIYV
GNIKLKVLHTPGHTPESISFLLTDEGAGAQVPMGLFSGDFIFVGDIGRPDLLEKAVKVEGLSEIGAKQMFKSIESIKDLP
DYIQIWPGHGAGSPCGKSLGAIPTSTLGYEKQTNWAFSENNEATFIDKLISDQPAPPHHFAQMKKINQFGMNLYQPYTVY
PATSTNRLTFDLRSKEAYHGGHIEGTINIPYDKNFINQIGWYLNYNQEINLIGDYHLVSKATHNILYNLLDMIMCLDISY
HKLKFKHNLFIVKT

Sequences:

>Translated_334_residues
MIIDPICDLSSYIRVADEESLTITHAAETHIHANFVSGIRDVAIKLNASIYVSGESDDMLGYKNMPNHTHFVQHNDDIYV
GNIKLKVLHTPGHTPESISFLLTDEGAGAQVPMGLFSGDFIFVGDIGRPDLLEKAVKVEGLSEIGAKQMFKSIESIKDLP
DYIQIWPGHGAGSPCGKSLGAIPTSTLGYEKQTNWAFSENNEATFIDKLISDQPAPPHHFAQMKKINQFGMNLYQPYTVY
PATSTNRLTFDLRSKEAYHGGHIEGTINIPYDKNFINQIGWYLNYNQEINLIGDYHLVSKATHNILYNLLDMIMCLDISY
HKLKFKHNLFIVKT
>Mature_334_residues
MIIDPICDLSSYIRVADEESLTITHAAETHIHANFVSGIRDVAIKLNASIYVSGESDDMLGYKNMPNHTHFVQHNDDIYV
GNIKLKVLHTPGHTPESISFLLTDEGAGAQVPMGLFSGDFIFVGDIGRPDLLEKAVKVEGLSEIGAKQMFKSIESIKDLP
DYIQIWPGHGAGSPCGKSLGAIPTSTLGYEKQTNWAFSENNEATFIDKLISDQPAPPHHFAQMKKINQFGMNLYQPYTVY
PATSTNRLTFDLRSKEAYHGGHIEGTINIPYDKNFINQIGWYLNYNQEINLIGDYHLVSKATHNILYNLLDMIMCLDISY
HKLKFKHNLFIVKT

Specific function: Unknown

COG id: COG0491

COG function: function code R; Zn-dependent hydrolases, including glyoxylases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 rhodanese domain [H]

Homologues:

Organism=Homo sapiens, GI21703352, Length=186, Percent_Identity=27.9569892473118, Blast_Score=73, Evalue=4e-13,
Organism=Homo sapiens, GI116642887, Length=186, Percent_Identity=27.9569892473118, Blast_Score=72, Evalue=8e-13,
Organism=Escherichia coli, GI1787158, Length=208, Percent_Identity=27.4038461538462, Blast_Score=65, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001279
- InterPro:   IPR001763 [H]

Pfam domain/function: PF00753 Lactamase_B; PF00581 Rhodanese [H]

EC number: NA

Molecular weight: Translated: 37448; Mature: 37448

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIIDPICDLSSYIRVADEESLTITHAAETHIHANFVSGIRDVAIKLNASIYVSGESDDML
CCCCCCCCHHHHHEECCCCCEEEEEECCCEEHHHHHHHHEEEEEEEEEEEEEECCCCCCC
GYKNMPNHTHFVQHNDDIYVGNIKLKVLHTPGHTPESISFLLTDEGAGAQVPMGLFSGDF
CCCCCCCCCEEEEECCCEEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCCCEEEECCCE
IFVGDIGRPDLLEKAVKVEGLSEIGAKQMFKSIESIKDLPDYIQIWPGHGAGSPCGKSLG
EEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCC
AIPTSTLGYEKQTNWAFSENNEATFIDKLISDQPAPPHHFAQMKKINQFGMNLYQPYTVY
CCCCCCCCCCCCCCCEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHCCCEEEE
PATSTNRLTFDLRSKEAYHGGHIEGTINIPYDKNFINQIGWYLNYNQEINLIGDYHLVSK
CCCCCCEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHCCEEEECCCEEEEEECHHHHHH
ATHNILYNLLDMIMCLDISYHKLKFKHNLFIVKT
HHHHHHHHHHHHHHHHCCCHHEEEEECCEEEEEC
>Mature Secondary Structure
MIIDPICDLSSYIRVADEESLTITHAAETHIHANFVSGIRDVAIKLNASIYVSGESDDML
CCCCCCCCHHHHHEECCCCCEEEEEECCCEEHHHHHHHHEEEEEEEEEEEEEECCCCCCC
GYKNMPNHTHFVQHNDDIYVGNIKLKVLHTPGHTPESISFLLTDEGAGAQVPMGLFSGDF
CCCCCCCCCEEEEECCCEEEEEEEEEEEECCCCCCCCEEEEEECCCCCCCCCEEEECCCE
IFVGDIGRPDLLEKAVKVEGLSEIGAKQMFKSIESIKDLPDYIQIWPGHGAGSPCGKSLG
EEEECCCCHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCCCCCCCCCC
AIPTSTLGYEKQTNWAFSENNEATFIDKLISDQPAPPHHFAQMKKINQFGMNLYQPYTVY
CCCCCCCCCCCCCCCEECCCCCHHHHHHHHCCCCCCCHHHHHHHHHHHHCCHHCCCEEEE
PATSTNRLTFDLRSKEAYHGGHIEGTINIPYDKNFINQIGWYLNYNQEINLIGDYHLVSK
CCCCCCEEEEEECCCCCCCCCCEEEEEECCCCHHHHHHCCEEEECCCEEEEEECHHHHHH
ATHNILYNLLDMIMCLDISYHKLKFKHNLFIVKT
HHHHHHHHHHHHHHHHCCCHHEEEEECCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]