Click here to switch to the map view.

The map label for this gene is cysS [H]

Identifier: 161501802

GI number: 161501802

Start: 2974902

End: 2976284

Strand: Reverse

Name: cysS [H]

Synonym: VV1_2908

Alternate gene names: 161501802

Gene position: 2976284-2974902 (Counterclockwise)

Preceding gene: 27366191

Following gene: 326424096

Centisome position: 90.69

GC content: 47.87

Gene sequence:

>1383_bases
ATGTTGAAGATATATAACACACTGACAAGACAGAAAGAGGAATTCAAACCAATCACAGCCGGTAAAGTCGGTATGTATGT
CTGTGGAGTTACCATTTACGATCTCTGTCACATCGGTCATGGCCGTACATTTGTCTCTTTTGACGTCGTATCTCGTTACT
TGCGCTATTTAGGTTACGATCTGACGTTTGTGCGCAACATTACCGATATCGATGACAAAATCATCAAACGTGCGGCGGAA
AACGGTGAAACCTGTGATTCATTGACCGAACGTTTGATCGGTGAAATGCACGCTGACTTCGATGCGCTAAACATGAAGCG
CCCAGATGTGGAACCGCGCGCAACGCAATACATTCAAGAAATCATTGAGTTAGTTGAAAGACTGATTGAACGTGGTTTTG
CGTATGTCGCCGACAACGGTGATGTGATGTTTGAAGTCAATAAATTTGACGAATACGGTAAGCTTTCTAAGCAAGACCTT
GACCAGCTTCAAGCGGGCGCGCGCGTCGATGTAGAAACAGCAAAACGCTGTCCTCTGGATTTCGTACTTTGGAAAATGTC
CAAGCCGGGTGAGCCTACATGGGAATCACCATGGGGGCCAGGTCGTCCTGGTTGGCACATCGAATGTTCGGCAATGAACT
CGTCCATTCTTGGTAATCATTTTGATATTCACGGCGGTGGCTCTGATCTTCAGTTCCCTCACCACGAAAACGAAATTGCT
CAGTCTTGCTGTGCCCATGACACTCAGTATGTAAATACTTGGATGCACAGCGGTATGGTGATGGTCGACAAAGAGAAGAT
GTCTAAGTCTCTAGGTAACTTCTTCACTATTCGCGATGTGTTAGGTCACTATGATGCGGAAACCGTACGTTACTTCCTAA
TGTCGGGTCACTACCGCAGCCAGCTTAACTACAGCGAAGAAAATCTCAACCAAGCTCGCGCGTCACTAGAGCGCCTATAC
ACTTCTCTGCGTGGTTTGGATTTCTCGGCTGCGCCAGCAGGTGGTGAAGAGTATGTGTCACGCTTTACCGCAGCAATGAA
CGACGATTTCAACACGCCGGAAGCCTATTCCGTGTTGTTTGATATGGCGCGTGAGATCAACCGATTGAAAACGGAAGATC
TGGCCAACGCCAGTGCTTTAGGTGCCTTGATGCGTGAGCTTGCTGACGTGATCGGCATTCTTCATCAAGATCCAGACGCG
TTTTTGAAAGGTGACGCGGGCAATGATGATGAAGTGGCAGAAATTGAAGCGCTGATCAAACTGCGTAACGATTCTCGTGC
GGCGAAAGATTGGGCAAACGCGGATATGGCGCGCGATAAGCTGAACGAAATGGGTATCGTACTTGAAGATGGCCCTGAAG
GAACAACGTGGCGTCGCAAGTAA

Upstream 100 bases:

>100_bases
AGCCGATTATCGTTTTTCAGCGGAATTGTTATTACCTAAAAACAATGTAGTTGGTATACTGCCGATTCATTTTAGTTCAA
TCAATATACAGATAGAGATC

Downstream 100 bases:

>100_bases
TTGCATCTTTTTAAAGGGCTGTTGATTCAGCCCTTTTCTTTATATTTTTACATTTTCCAATTTTACTTAGGTAGTGCTCT
GTGGCTCAGATGTATTTCTA

Product: cysteinyl-tRNA synthetase

Products: NA

Alternate protein names: Cysteine--tRNA ligase; CysRS [H]

Number of amino acids: Translated: 460; Mature: 460

Protein sequence:

>460_residues
MLKIYNTLTRQKEEFKPITAGKVGMYVCGVTIYDLCHIGHGRTFVSFDVVSRYLRYLGYDLTFVRNITDIDDKIIKRAAE
NGETCDSLTERLIGEMHADFDALNMKRPDVEPRATQYIQEIIELVERLIERGFAYVADNGDVMFEVNKFDEYGKLSKQDL
DQLQAGARVDVETAKRCPLDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSSILGNHFDIHGGGSDLQFPHHENEIA
QSCCAHDTQYVNTWMHSGMVMVDKEKMSKSLGNFFTIRDVLGHYDAETVRYFLMSGHYRSQLNYSEENLNQARASLERLY
TSLRGLDFSAAPAGGEEYVSRFTAAMNDDFNTPEAYSVLFDMAREINRLKTEDLANASALGALMRELADVIGILHQDPDA
FLKGDAGNDDEVAEIEALIKLRNDSRAAKDWANADMARDKLNEMGIVLEDGPEGTTWRRK

Sequences:

>Translated_460_residues
MLKIYNTLTRQKEEFKPITAGKVGMYVCGVTIYDLCHIGHGRTFVSFDVVSRYLRYLGYDLTFVRNITDIDDKIIKRAAE
NGETCDSLTERLIGEMHADFDALNMKRPDVEPRATQYIQEIIELVERLIERGFAYVADNGDVMFEVNKFDEYGKLSKQDL
DQLQAGARVDVETAKRCPLDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSSILGNHFDIHGGGSDLQFPHHENEIA
QSCCAHDTQYVNTWMHSGMVMVDKEKMSKSLGNFFTIRDVLGHYDAETVRYFLMSGHYRSQLNYSEENLNQARASLERLY
TSLRGLDFSAAPAGGEEYVSRFTAAMNDDFNTPEAYSVLFDMAREINRLKTEDLANASALGALMRELADVIGILHQDPDA
FLKGDAGNDDEVAEIEALIKLRNDSRAAKDWANADMARDKLNEMGIVLEDGPEGTTWRRK
>Mature_460_residues
MLKIYNTLTRQKEEFKPITAGKVGMYVCGVTIYDLCHIGHGRTFVSFDVVSRYLRYLGYDLTFVRNITDIDDKIIKRAAE
NGETCDSLTERLIGEMHADFDALNMKRPDVEPRATQYIQEIIELVERLIERGFAYVADNGDVMFEVNKFDEYGKLSKQDL
DQLQAGARVDVETAKRCPLDFVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSSILGNHFDIHGGGSDLQFPHHENEIA
QSCCAHDTQYVNTWMHSGMVMVDKEKMSKSLGNFFTIRDVLGHYDAETVRYFLMSGHYRSQLNYSEENLNQARASLERLY
TSLRGLDFSAAPAGGEEYVSRFTAAMNDDFNTPEAYSVLFDMAREINRLKTEDLANASALGALMRELADVIGILHQDPDA
FLKGDAGNDDEVAEIEALIKLRNDSRAAKDWANADMARDKLNEMGIVLEDGPEGTTWRRK

Specific function: Unknown

COG id: COG0215

COG function: function code J; Cysteinyl-tRNA synthetase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I aminoacyl-tRNA synthetase family [H]

Homologues:

Organism=Homo sapiens, GI13375695, Length=494, Percent_Identity=34.2105263157895, Blast_Score=255, Evalue=7e-68,
Organism=Homo sapiens, GI21269877, Length=233, Percent_Identity=43.7768240343348, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI10835051, Length=233, Percent_Identity=43.7768240343348, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI303304987, Length=233, Percent_Identity=43.7768240343348, Blast_Score=201, Evalue=1e-51,
Organism=Homo sapiens, GI62240992, Length=233, Percent_Identity=43.7768240343348, Blast_Score=201, Evalue=2e-51,
Organism=Escherichia coli, GI1786737, Length=461, Percent_Identity=76.5726681127983, Blast_Score=723, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17509797, Length=247, Percent_Identity=40.8906882591093, Blast_Score=184, Evalue=8e-47,
Organism=Caenorhabditis elegans, GI17509795, Length=247, Percent_Identity=40.8906882591093, Blast_Score=184, Evalue=8e-47,
Organism=Saccharomyces cerevisiae, GI6324082, Length=378, Percent_Identity=33.0687830687831, Blast_Score=207, Evalue=4e-54,
Organism=Drosophila melanogaster, GI19922218, Length=499, Percent_Identity=35.0701402805611, Blast_Score=270, Evalue=2e-72,
Organism=Drosophila melanogaster, GI19922364, Length=323, Percent_Identity=36.2229102167183, Blast_Score=196, Evalue=3e-50,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015803
- InterPro:   IPR015273
- InterPro:   IPR014729
- InterPro:   IPR009080 [H]

Pfam domain/function: PF09190 DALR_2; PF01406 tRNA-synt_1e [H]

EC number: =6.1.1.16 [H]

Molecular weight: Translated: 52083; Mature: 52083

Theoretical pI: Translated: 4.76; Mature: 4.76

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKIYNTLTRQKEEFKPITAGKVGMYVCGVTIYDLCHIGHGRTFVSFDVVSRYLRYLGYD
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCC
LTFVRNITDIDDKIIKRAAENGETCDSLTERLIGEMHADFDALNMKRPDVEPRATQYIQE
HHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHH
IIELVERLIERGFAYVADNGDVMFEVNKFDEYGKLSKQDLDQLQAGARVDVETAKRCPLD
HHHHHHHHHHCCCEEEECCCCEEEEECCCCHHCCCCHHHHHHHHCCCCCCHHHHHHCCHH
FVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSSILGNHFDIHGGGSDLQFPHHENEIA
HHEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCHHHHH
QSCCAHDTQYVNTWMHSGMVMVDKEKMSKSLGNFFTIRDVLGHYDAETVRYFLMSGHYRS
HHHHHCCHHHHHHHHHCCEEEEEHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCHHH
QLNYSEENLNQARASLERLYTSLRGLDFSAAPAGGEEYVSRFTAAMNDDFNTPEAYSVLF
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
DMAREINRLKTEDLANASALGALMRELADVIGILHQDPDAFLKGDAGNDDEVAEIEALIK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCHHHHHHHHHHH
LRNDSRAAKDWANADMARDKLNEMGIVLEDGPEGTTWRRK
HHCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCC
>Mature Secondary Structure
MLKIYNTLTRQKEEFKPITAGKVGMYVCGVTIYDLCHIGHGRTFVSFDVVSRYLRYLGYD
CCCHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCCCEEEEHHHHHHHHHHHCCC
LTFVRNITDIDDKIIKRAAENGETCDSLTERLIGEMHADFDALNMKRPDVEPRATQYIQE
HHHHHCHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCHHHCCCCCCCCCHHHHHHHHH
IIELVERLIERGFAYVADNGDVMFEVNKFDEYGKLSKQDLDQLQAGARVDVETAKRCPLD
HHHHHHHHHHCCCEEEECCCCEEEEECCCCHHCCCCHHHHHHHHCCCCCCHHHHHHCCHH
FVLWKMSKPGEPTWESPWGPGRPGWHIECSAMNSSILGNHFDIHGGGSDLQFPHHENEIA
HHEEECCCCCCCCCCCCCCCCCCCCEEEEECCCCCCCCCCCEECCCCCCCCCCCCHHHHH
QSCCAHDTQYVNTWMHSGMVMVDKEKMSKSLGNFFTIRDVLGHYDAETVRYFLMSGHYRS
HHHHHCCHHHHHHHHHCCEEEEEHHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHCCCHHH
QLNYSEENLNQARASLERLYTSLRGLDFSAAPAGGEEYVSRFTAAMNDDFNTPEAYSVLF
HCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCHHHHHHH
DMAREINRLKTEDLANASALGALMRELADVIGILHQDPDAFLKGDAGNDDEVAEIEALIK
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCHHHEECCCCCCHHHHHHHHHHH
LRNDSRAAKDWANADMARDKLNEMGIVLEDGPEGTTWRRK
HHCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA