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The map label for this gene is ribH

Identifier: 161486646

GI number: 161486646

Start: 869360

End: 869830

Strand: Direct

Name: ribH

Synonym: VV0864

Alternate gene names: 161486646

Gene position: 869360-869830 (Clockwise)

Preceding gene: 37679047

Following gene: 37679049

Centisome position: 25.92

GC content: 44.8

Gene sequence:

>471_bases
ATGAAAGTGATCGAGGGTGGCTTCCCTGCGCCAAACGCAAAAATTGCTATCGTTATTTCTCGTTTCAACAGTTTTATTAA
CGAAAGTCTATTGTCTGGTGCCATCGACACTTTGAAGCGTCACGGTCAAGTCAGTGAAGACAACATCACCGTTGTACGTT
GTCCTGGTGCTGTTGAACTACCTCTAGTGGCTCAGCGCGTAGCAAAAACAGGTAAGTTCGACGCGATTGTATCTCTTGGC
TCAGTGATCCGTGGTGGTACACCACACTTTGACTATGTTTGTAGTGAAATGAATAAAGGTCTCGCACAAGTGTCTCTTGA
ATTTAGCATTCCAGTGGCGTTTGGTGTTTTGACCGTTGATACTATCGATCAAGCTATTGAACGCGCAGGAACCAAGGCTG
GTAACAAAGGTGCAGAAGCTGCACTGAGCGCACTTGAGATGATAAACGTTCTTTCTGAAATTGATTCCTAA

Upstream 100 bases:

>100_bases
TAAGGCAGTATTTCGTGGCGAAATACCATTAGATATTGCTCACAAAATTGTGCTAGAATCCGGCGATTCTCACTTGATGA
ACATAGTTAAAGGAAGGCTT

Downstream 100 bases:

>100_bases
TGGGGGCCAGTGTGAAACCAGCCGCACGTCGTAACGCACGTCAATTCGCTTTACAAGCAATCTATTCATGGCAAATTACT
AAAGAAAATGTTGCCACTAT

Product: 6,7-dimethyl-8-ribityllumazine synthase

Products: NA

Alternate protein names: DMRL synthase; Lumazine synthase; Riboflavin synthase beta chain [H]

Number of amino acids: Translated: 156; Mature: 156

Protein sequence:

>156_residues
MKVIEGGFPAPNAKIAIVISRFNSFINESLLSGAIDTLKRHGQVSEDNITVVRCPGAVELPLVAQRVAKTGKFDAIVSLG
SVIRGGTPHFDYVCSEMNKGLAQVSLEFSIPVAFGVLTVDTIDQAIERAGTKAGNKGAEAALSALEMINVLSEIDS

Sequences:

>Translated_156_residues
MKVIEGGFPAPNAKIAIVISRFNSFINESLLSGAIDTLKRHGQVSEDNITVVRCPGAVELPLVAQRVAKTGKFDAIVSLG
SVIRGGTPHFDYVCSEMNKGLAQVSLEFSIPVAFGVLTVDTIDQAIERAGTKAGNKGAEAALSALEMINVLSEIDS
>Mature_156_residues
MKVIEGGFPAPNAKIAIVISRFNSFINESLLSGAIDTLKRHGQVSEDNITVVRCPGAVELPLVAQRVAKTGKFDAIVSLG
SVIRGGTPHFDYVCSEMNKGLAQVSLEFSIPVAFGVLTVDTIDQAIERAGTKAGNKGAEAALSALEMINVLSEIDS

Specific function: Riboflavin synthase is a bifunctional enzyme complex catalyzing the formation of riboflavin from 5-amino-6-(1'-D)- ribityl-amino-2,4(1H,3H)-pyrimidinedione and L-3,4-dihydrohy-2- butanone-4-phosphate via 6,7-dimethyl-8-lumazine. The beta subunit catalyzes

COG id: COG0054

COG function: function code H; Riboflavin synthase beta-chain

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the DMRL synthase family [H]

Homologues:

Organism=Escherichia coli, GI1786617, Length=156, Percent_Identity=64.7435897435898, Blast_Score=209, Evalue=5e-56,
Organism=Saccharomyces cerevisiae, GI6324429, Length=149, Percent_Identity=32.8859060402685, Blast_Score=84, Evalue=1e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002180 [H]

Pfam domain/function: PF00885 DMRL_synthase [H]

EC number: =2.5.1.9 [H]

Molecular weight: Translated: 16414; Mature: 16414

Theoretical pI: Translated: 5.20; Mature: 5.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKVIEGGFPAPNAKIAIVISRFNSFINESLLSGAIDTLKRHGQVSEDNITVVRCPGAVEL
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCH
PLVAQRVAKTGKFDAIVSLGSVIRGGTPHFDYVCSEMNKGLAQVSLEFSIPVAFGVLTVD
HHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHEEEEEECCHHHHHHHHH
TIDQAIERAGTKAGNKGAEAALSALEMINVLSEIDS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKVIEGGFPAPNAKIAIVISRFNSFINESLLSGAIDTLKRHGQVSEDNITVVRCPGAVEL
CCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCCH
PLVAQRVAKTGKFDAIVSLGSVIRGGTPHFDYVCSEMNKGLAQVSLEFSIPVAFGVLTVD
HHHHHHHHHCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCHHHEEEEEECCHHHHHHHHH
TIDQAIERAGTKAGNKGAEAALSALEMINVLSEIDS
HHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA