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The map label for this gene is etp

Identifier: 161486513

GI number: 161486513

Start: 1036098

End: 1036544

Strand: Reverse

Name: etp

Synonym: S1051

Alternate gene names: 161486513

Gene position: 1036544-1036098 (Counterclockwise)

Preceding gene: 30062520

Following gene: 30062509

Centisome position: 22.54

GC content: 51.9

Gene sequence:

>447_bases
ATGGCCCAACTAAAATTTAACTCAATCCTAGTGGTTTGTACCGGCAACATTTGCCGTTCGCCCATTGGCGAGCGCTTGCT
GCGTAAACGTCTGCCGGGCGTAAAAGTCAAATCGGCAGGTGTTCATGGTCTGGTAAAACACCCTGCAGATGCGACAGCGG
CAGATGTTGCCGCTAATCATGGCGTATCTCTTGAAGGACATGCCGGACGTAAGCTCACTGCTGAGATGGCACGAAATTAC
GATCTGATTCTGGCAATGGAGTCGGAACATATTGCTCAGGTTACCGCAATTGCTCCCGAGGTCCGCGGGAAGACAATGCT
GTTTGGGCAATGGCTGGAACAGAAAGAGATCCCGGATCCCTATCGTAAAAGTCAGGACGCATTTGAACATGTCTACAGTA
TGTTGGAGCGCGCCAGTCAGGAATGGGCGAAGCGCCTCAGCCGGTAA

Upstream 100 bases:

>100_bases
CTACCGCGCCGCTGGCTCGTTGGAACCGTGTGATTTCTCTGCTGGTACCGACGATTTCCGGGGTGCATGACCTGACAGAG
ACTTCACGGTGGATTCAAAC

Downstream 100 bases:

>100_bases
TTTGAGTTTATAAAATACGATGACAACTAAAAATATGAATACGCCACCAGGCAGCACTCAGGAAAATGAGATCGATCTGC
TTCGTCTGGTCGGCGAGTTA

Product: phosphotyrosine-protein phosphatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 148; Mature: 147

Protein sequence:

>148_residues
MAQLKFNSILVVCTGNICRSPIGERLLRKRLPGVKVKSAGVHGLVKHPADATAADVAANHGVSLEGHAGRKLTAEMARNY
DLILAMESEHIAQVTAIAPEVRGKTMLFGQWLEQKEIPDPYRKSQDAFEHVYSMLERASQEWAKRLSR

Sequences:

>Translated_148_residues
MAQLKFNSILVVCTGNICRSPIGERLLRKRLPGVKVKSAGVHGLVKHPADATAADVAANHGVSLEGHAGRKLTAEMARNY
DLILAMESEHIAQVTAIAPEVRGKTMLFGQWLEQKEIPDPYRKSQDAFEHVYSMLERASQEWAKRLSR
>Mature_147_residues
AQLKFNSILVVCTGNICRSPIGERLLRKRLPGVKVKSAGVHGLVKHPADATAADVAANHGVSLEGHAGRKLTAEMARNYD
LILAMESEHIAQVTAIAPEVRGKTMLFGQWLEQKEIPDPYRKSQDAFEHVYSMLERASQEWAKRLSR

Specific function: Dephosphorylates etk [H]

COG id: COG0394

COG function: function code T; Protein-tyrosine-phosphatase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the low molecular weight phosphotyrosine protein phosphatase family [H]

Homologues:

Organism=Homo sapiens, GI4757714, Length=157, Percent_Identity=30.5732484076433, Blast_Score=75, Evalue=1e-14,
Organism=Homo sapiens, GI6005988, Length=157, Percent_Identity=30.5732484076433, Blast_Score=70, Evalue=6e-13,
Organism=Escherichia coli, GI87081812, Length=148, Percent_Identity=99.3243243243243, Blast_Score=306, Evalue=4e-85,
Organism=Escherichia coli, GI1788375, Length=142, Percent_Identity=56.3380281690141, Blast_Score=175, Evalue=9e-46,
Organism=Drosophila melanogaster, GI78706770, Length=151, Percent_Identity=32.4503311258278, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI78706772, Length=151, Percent_Identity=32.4503311258278, Blast_Score=67, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000106
- InterPro:   IPR017867 [H]

Pfam domain/function: PF01451 LMWPc [H]

EC number: =3.1.3.48 [H]

Molecular weight: Translated: 16416; Mature: 16285

Theoretical pI: Translated: 9.86; Mature: 9.86

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.7 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAQLKFNSILVVCTGNICRSPIGERLLRKRLPGVKVKSAGVHGLVKHPADATAADVAANH
CCCCCCCCEEEEEECHHHCCHHHHHHHHHHCCCCEEECCCCCHHHCCCCCCHHHHHHHCC
GVSLEGHAGRKLTAEMARNYDLILAMESEHIAQVTAIAPEVRGKTMLFGQWLEQKEIPDP
CCCCCCCCCCHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCH
YRKSQDAFEHVYSMLERASQEWAKRLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
AQLKFNSILVVCTGNICRSPIGERLLRKRLPGVKVKSAGVHGLVKHPADATAADVAANH
CCCCCCCEEEEEECHHHCCHHHHHHHHHHCCCCEEECCCCCHHHCCCCCCHHHHHHHCC
GVSLEGHAGRKLTAEMARNYDLILAMESEHIAQVTAIAPEVRGKTMLFGQWLEQKEIPDP
CCCCCCCCCCHHHHHHHCCCEEEEEECCHHHHHHHHHCCCCCCCCHHHHHHHHHCCCCCH
YRKSQDAFEHVYSMLERASQEWAKRLSR
HHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]