Click here to switch to the map view.

The map label for this gene is murZ [H]

Identifier: 161485741

GI number: 161485741

Start: 1072331

End: 1073590

Strand: Reverse

Name: murZ [H]

Synonym: SpyM3_1033

Alternate gene names: 161485741

Gene position: 1073590-1072331 (Counterclockwise)

Preceding gene: 21910570

Following gene: 21910568

Centisome position: 56.49

GC content: 41.43

Gene sequence:

>1260_bases
ATGCGTAAAATTATTATTAATGGCGGAAAAGCCTTATCTGGAGAAGTGGCAGTTTCAGGGGCAAAAAACAGTGTTGTTGC
GCTTATTCCAGCAATCATCTTAGCCGATGATATTGTGATTCTTGATGGTGTACCTGCTATTAGTGATGTAGATAGTCTGA
TTGAAATCATGGAGCTTATGGGAGCAACAGTAAACTATCATGGTGATACTTTAGAAATTGACCCTAGAGGGGTGCAAGAC
ATCCCGATGCCTTACGGAAAGATTAATAGTCTTCGAGCTTCCTATTATTTCTACGGTAGTCTTTTAGGTCGTTTTGGACA
AGCAGTTGTTGGCTTACCTGGTGGTTGCGATTTAGGACCAAGACCAATTGACTTGCATTTGAAGGCCTTCGAGGCTATGG
GAGTTGAAGTGTCTTATGAGGGTGAAAATATGAATTTATCGACAAATGGTCAAAAAATTCATGGCGCTCATATCTATATG
GACACCGTTAGTGTCGGTGCTACAATTAATACTATGGTTGCGGCAACAAAAGCTCAAGGTAAAACGGTTATTGAAAACGC
TGCACGCGAGCCAGAGATTATTGATGTGGCTACTCTTTTGAATAACATGGGTGCGCATATTCGTGGAGCAGGTACAGATA
TTATTACGATACAAGGTGTTCAGAAATTGCATGGTACTAGACACCAAGTTATTCCTGATCGTATTGAAGCAGGGACTTAT
ATCGCTTTGGCGGCAGCTATTGGAAAAGGTGTTAAGATCACTAATGTTCTTTATGAGCATTTAGAGAGTTTCATTGCTAA
GTTAGAAGAAATGGGTGTCCGTATGACGGTAGAAGAGGATGCTATCTTTGTTGAAAAGCAAGAATCCCTCAAGGCTATTA
CAATTAAAACATCTCCTTACCCTGGCTTTGCCACTGATTTGCAACAGCCATTAACGCCCTTGTTGTTAAAAGCAGATGGT
CGTGGAACGATTATTGACACTATATATGAAAAGCGCATTAACCATGTGCCAGAGTTGATGCGCATGGGAGCAGATATCTC
AGTTATTGGTGGTCAGATTGTTTATCAAGGGCCGTCTCGCCTGACAGGAGCTCAGGTCAAAGCCACTGATTTACGTGCCG
GAGCGGCTCTAGTGACTGCTGGTCTAATGGCTGAAGGCAAGACAGAAATTACTAATATTGAATTTATCTTACGTGGCTAT
GCTAGTATCATTGCAAAATTAACAGCACTAGGGGCAGATATTCAATTAATCGAAGACTAA

Upstream 100 bases:

>100_bases
AAAAGGGATGATTAAAAATTAAGACGTCAATAATTGTCAGGCTTCATGATTTATGATAAAATGAAAAGGTTGAATTCTAG
TATAAGAAAGTTTTGAATGT

Downstream 100 bases:

>100_bases
AGAGAAGCTAACGCTTCTCTTTTTTATATTACATGTGCTTAGGCTAATAATACTTAGGTGCATACTTTGTTGCATTTTAT
GGCTTTTTAACTGTCATAAA

Product: UDP-N-acetylglucosamine 1-carboxyvinyltransferase

Products: NA

Alternate protein names: Enoylpyruvate transferase 2; UDP-N-acetylglucosamine enolpyruvyl transferase 2; EPT 2 [H]

Number of amino acids: Translated: 419; Mature: 419

Protein sequence:

>419_residues
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQD
IPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTY
IALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADG
RGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLMAEGKTEITNIEFILRGY
ASIIAKLTALGADIQLIED

Sequences:

>Translated_419_residues
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQD
IPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTY
IALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADG
RGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLMAEGKTEITNIEFILRGY
ASIIAKLTALGADIQLIED
>Mature_419_residues
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELMGATVNYHGDTLEIDPRGVQD
IPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGPRPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYM
DTVSVGATINTMVAATKAQGKTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTY
IALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPYPGFATDLQQPLTPLLLKADG
RGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSRLTGAQVKATDLRAGAALVTAGLMAEGKTEITNIEFILRGY
ASIIAKLTALGADIQLIED

Specific function: Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine [H]

COG id: COG0766

COG function: function code M; UDP-N-acetylglucosamine enolpyruvyl transferase

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family. MurA subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789580, Length=420, Percent_Identity=44.7619047619048, Blast_Score=343, Evalue=9e-96,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR013792
- InterPro:   IPR005750 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.7 [H]

Molecular weight: Translated: 44681; Mature: 44681

Theoretical pI: Translated: 5.14; Mature: 5.14

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELM
CCEEEEECCCEECCCEEEECCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHH
GATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGP
CCEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
RPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYMDTVSVGATINTMVAATKAQG
CCEEEEEEEEHHCCEEEEECCCCEEEECCCCEEEEEEEEEEEEECCCCHHHHEEECCCCC
KTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTY
CHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCEEEEECCHHHHCCCCCCCCCHHHCCCCC
IALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPY
EEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCEEEEEECCCC
PGFATDLQQPLTPLLLKADGRGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSR
CCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCC
LTGAQVKATDLRAGAALVTAGLMAEGKTEITNIEFILRGYASIIAKLTALGADIQLIED
CCCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC
>Mature Secondary Structure
MRKIIINGGKALSGEVAVSGAKNSVVALIPAIILADDIVILDGVPAISDVDSLIEIMELM
CCEEEEECCCEECCCEEEECCCCCHHHHHHHHHHHCCEEEECCCCCHHHHHHHHHHHHHH
GATVNYHGDTLEIDPRGVQDIPMPYGKINSLRASYYFYGSLLGRFGQAVVGLPGGCDLGP
CCEEEECCCEEEECCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCC
RPIDLHLKAFEAMGVEVSYEGENMNLSTNGQKIHGAHIYMDTVSVGATINTMVAATKAQG
CCEEEEEEEEHHCCEEEEECCCCEEEECCCCEEEEEEEEEEEEECCCCHHHHEEECCCCC
KTVIENAAREPEIIDVATLLNNMGAHIRGAGTDIITIQGVQKLHGTRHQVIPDRIEAGTY
CHHHHHCCCCCCHHHHHHHHHHCCCEEECCCCEEEEECCHHHHCCCCCCCCCHHHCCCCC
IALAAAIGKGVKITNVLYEHLESFIAKLEEMGVRMTVEEDAIFVEKQESLKAITIKTSPY
EEEEHHHCCCCCHHHHHHHHHHHHHHHHHHCCCEEEEECCEEEEEECCCCEEEEEECCCC
PGFATDLQQPLTPLLLKADGRGTIIDTIYEKRINHVPELMRMGADISVIGGQIVYQGPSR
CCHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHHHHHHHHHCCCCEEEECCEEEECCCCC
LTGAQVKATDLRAGAALVTAGLMAEGKTEITNIEFILRGYASIIAKLTALGADIQLIED
CCCCEEEECCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11296296 [H]