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The map label for this gene is rpl18p [H]

Identifier: 161485668

GI number: 161485668

Start: 2547926

End: 2548450

Strand: Direct

Name: rpl18p [H]

Synonym: MM_2143

Alternate gene names: 161485668

Gene position: 2547926-2548450 (Clockwise)

Preceding gene: 21228244

Following gene: 21228246

Centisome position: 62.2

GC content: 48.19

Gene sequence:

>525_bases
ATGGCAACAGGACCAAGATATAAGGTTCCTTTTAGAAGAAGAAGAGAAGGACGCACCAATTACCACCTCCGCCTTAAATT
ACTACTCTCAGGGCAGGACCGTGTGGTTGTCAGAAAGAGTGCAAGAAACGTTCAGATCCAGTTACTAGCTCCGACCCCTG
AAGGGGACATAACATATTCCTCAGCCGTTTCAAGTGAACTTGCAAAGTACGGTTACACAGGAGCTACCGGAAACACAACG
GCTGCATACCTTACAGGGCTCTTATTCGGGCTGAAGAGTTTGCAGAAGGGCTATGAAGGAGGCATTCTGGACATAGGTCT
CCAGGCTTCCTCTGCAGGTTCAAGAGTTTACGCCGCCCTTAAAGGGATCGTAGATTCTGGCTTTGAAATTCCATGCAGTT
CCGACGTGTTCCCCTCTGACGAGAGGATCCGCGGAGAGCACATAGCCGAATACAGAGAAGAGAGCTCAGACCTGCCAGAG
CAGTTTGAAGCAACCAAAGAGAAAATCTTTGCTGAATTTAGTTAA

Upstream 100 bases:

>100_bases
TATAGAAAGGCAAAAGGCGGAGAATACAGAAGCGTTTCTCACCTGAACTCCCACCTTGAGTCCGAAAAACTGTTACAGAA
ATAACCTGGAGGAGCTGAAA

Downstream 100 bases:

>100_bases
GGTGATTAAATGGCATTCGATCAAGATTGGGTCCCGAAAACCAGGCTTGGAAAATTAGTCGTTGAAGGACAGGTTGCTTC
CATGGACGAAGCAATCAAAT

Product: 50S ribosomal protein L18P

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 174; Mature: 173

Protein sequence:

>174_residues
MATGPRYKVPFRRRREGRTNYHLRLKLLLSGQDRVVVRKSARNVQIQLLAPTPEGDITYSSAVSSELAKYGYTGATGNTT
AAYLTGLLFGLKSLQKGYEGGILDIGLQASSAGSRVYAALKGIVDSGFEIPCSSDVFPSDERIRGEHIAEYREESSDLPE
QFEATKEKIFAEFS

Sequences:

>Translated_174_residues
MATGPRYKVPFRRRREGRTNYHLRLKLLLSGQDRVVVRKSARNVQIQLLAPTPEGDITYSSAVSSELAKYGYTGATGNTT
AAYLTGLLFGLKSLQKGYEGGILDIGLQASSAGSRVYAALKGIVDSGFEIPCSSDVFPSDERIRGEHIAEYREESSDLPE
QFEATKEKIFAEFS
>Mature_173_residues
ATGPRYKVPFRRRREGRTNYHLRLKLLLSGQDRVVVRKSARNVQIQLLAPTPEGDITYSSAVSSELAKYGYTGATGNTTA
AYLTGLLFGLKSLQKGYEGGILDIGLQASSAGSRVYAALKGIVDSGFEIPCSSDVFPSDERIRGEHIAEYREESSDLPEQ
FEATKEKIFAEFS

Specific function: This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance [H]

COG id: COG0256

COG function: function code J; Ribosomal protein L18

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribosomal protein L18P family [H]

Homologues:

Organism=Homo sapiens, GI14591909, Length=218, Percent_Identity=30.2752293577982, Blast_Score=91, Evalue=4e-19,
Organism=Caenorhabditis elegans, GI17534333, Length=215, Percent_Identity=32.093023255814, Blast_Score=101, Evalue=2e-22,
Organism=Saccharomyces cerevisiae, GI6325126, Length=207, Percent_Identity=33.3333333333333, Blast_Score=105, Evalue=4e-24,
Organism=Drosophila melanogaster, GI116007384, Length=209, Percent_Identity=32.0574162679426, Blast_Score=96, Evalue=1e-20,
Organism=Drosophila melanogaster, GI116007382, Length=209, Percent_Identity=32.0574162679426, Blast_Score=96, Evalue=1e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005484
- InterPro:   IPR005485 [H]

Pfam domain/function: PF00861 Ribosomal_L18p [H]

EC number: NA

Molecular weight: Translated: 19132; Mature: 19001

Theoretical pI: Translated: 8.89; Mature: 8.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
0.6 %Met     (Translated Protein)
1.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
0.0 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATGPRYKVPFRRRREGRTNYHLRLKLLLSGQDRVVVRKSARNVQIQLLAPTPEGDITYS
CCCCCCCCCCHHHHHCCCCCEEEEEEEEECCCCEEEEEECCCCEEEEEEECCCCCCEEHH
SAVSSELAKYGYTGATGNTTAAYLTGLLFGLKSLQKGYEGGILDIGLQASSAGSRVYAAL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHH
KGIVDSGFEIPCSSDVFPSDERIRGEHIAEYREESSDLPEQFEATKEKIFAEFS
HHHHHCCCCCCCCCCCCCCCHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
ATGPRYKVPFRRRREGRTNYHLRLKLLLSGQDRVVVRKSARNVQIQLLAPTPEGDITYS
CCCCCCCCCHHHHHCCCCCEEEEEEEEECCCCEEEEEECCCCEEEEEEECCCCCCEEHH
SAVSSELAKYGYTGATGNTTAAYLTGLLFGLKSLQKGYEGGILDIGLQASSAGSRVYAAL
HHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHH
KGIVDSGFEIPCSSDVFPSDERIRGEHIAEYREESSDLPEQFEATKEKIFAEFS
HHHHHCCCCCCCCCCCCCCCHHHCHHHHHHHHHHCCCCHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11932238 [H]