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The map label for this gene is dinB1 [H]

Identifier: 161407222

GI number: 161407222

Start: 3273671

End: 3275035

Strand: Reverse

Name: dinB1 [H]

Synonym: Mmcs_3095

Alternate gene names: 161407222

Gene position: 3275035-3273671 (Counterclockwise)

Preceding gene: 108800063

Following gene: 108800059

Centisome position: 57.4

GC content: 72.01

Gene sequence:

>1365_bases
GTGGACGTGCGCTGGGTCCTGCACCTGGACATGGACGCGTTCTTCGCGTCGGTCGAGCAGTTGACCCGGCCCACCCTGCG
GGGACGGCCGGTGCTGGTCGGCGGTCTGGGCGGTCGCGGTGTGGTGGCCGGCGCCAGTTACGAGGCCAGGGTGCACGGCG
CACGTTCGGCGATGCCGATGCACCAGGCCCGCCGACTGGTCGGCGCACCGGCGGTGGTGCTGCCACCGCGAGGTGTGGTC
TACGGCCTGGCGAGCCGACGCGTGTTCGACACCGTGCGGACCCTGGTCCCGGTACTCGAACAGTTGTCGTTCGACGAGGC
GTTCGGCGAGCCGCAGGAGCTGGCCGGTGCGTCGGCGGCCGACGTCGAAGAGTTCTGCGAACTGTTGCGCGCGCGGGTGC
TGGAGGAGACCGGGCTGGTGGCCTCGGTGGGGGCGGGGTCGGGCAAGCAGATCGCCAAGATCGCCTCGGGCCTGGCCAAG
CCGGACGGCATCCGGGTGGTGCGCCGCGCCGACGAACGCCGTCTGCTCGACAGCCTGGCGGTGCGCAAGCTGTGGGGGAT
CGGACCGGTCGCCGAGGACAAACTGCACCGCCTCGGCATCGAGACCATCGGTCAGCTCGCGGCGCTCTCGGAGGCCGAGG
TAGCCGACATCCTCGGCGCCACCGTGGGTCCGGCGCTGCACCGGCTCGCCCGCGGCATCGACGAGCGGCCCGTCGCCGAA
CGGGCCGAGGCCAAACAGATCAGCGCCGAGTCCACGTTCCCGGCCGACCTCATCACCCTCGATCAGGTTCGCGAGGCGAT
CGGGCCGATCGCCGACCACGCCCACCGGCGACTGGCGAAGGACGGGCGCGGAGCCCGCACGGTCACCGTGAAGCTGAAGA
AGTCGGATATGAGCACGCTGACCCGGTCGGCCACGCTGCCGTCGGCCACCACCGACGCGGCGACGCTCAGCGCCACCGCC
CGCCGGCTGCTTGTCGACCCCGTCGAGATCGGCCCCATCCGCCTTGTGGGAGTGGGCTTTTCAGGCCTGTCGGAGGTGCG
CCAGGAGTCACTGTTCCCCGACCTGGAACTGGTGGAGGACGAACCGGCCACCCGTCCGGCGGTGCCGATGTCGGTGAGCG
AGGCGGCTGCCGTACCGCCGGCGTGGCGGGTCGGTGACGACGTCGCGCATCCGGAACTGGGGCACGGCTGGATCCAGGGG
GCCGGTCACGGGGTCATGACCATCCGGTTCGAGACGCGCAGCACCGGGCCGGGGCCGGCGAAGACCTTCCCCGACACGGT
GCCCGACGTCGTCCGGGCCAATCCGGTCGACAGCCTCGACTGGGCGGACTACGTGGACGCGCTCCCGCAGGCCGACCTGC
CCTGA

Upstream 100 bases:

>100_bases
AGGCGAGTTTGAGGAACTGACCGAGACGGATCGTGTCGTCACCGATCGGAACCTCGTGCGCCGCCATGACGCTCAGGCTA
ACGCCCTAGCATCTGCGGGT

Downstream 100 bases:

>100_bases
CACGTCAGCCCCATTCGGCGAGCACCTCGGCGGCCGGGACGTCCGCGGCGAGTGCGGCCATCAGCAGCACCCGCGCCTGC
GCGGGCCGCAGGGTCGGCAC

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV 1 [H]

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MDVRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARVHGARSAMPMHQARRLVGAPAVVLPPRGVV
YGLASRRVFDTVRTLVPVLEQLSFDEAFGEPQELAGASAADVEEFCELLRARVLEETGLVASVGAGSGKQIAKIASGLAK
PDGIRVVRRADERRLLDSLAVRKLWGIGPVAEDKLHRLGIETIGQLAALSEAEVADILGATVGPALHRLARGIDERPVAE
RAEAKQISAESTFPADLITLDQVREAIGPIADHAHRRLAKDGRGARTVTVKLKKSDMSTLTRSATLPSATTDAATLSATA
RRLLVDPVEIGPIRLVGVGFSGLSEVRQESLFPDLELVEDEPATRPAVPMSVSEAAAVPPAWRVGDDVAHPELGHGWIQG
AGHGVMTIRFETRSTGPGPAKTFPDTVPDVVRANPVDSLDWADYVDALPQADLP

Sequences:

>Translated_454_residues
MDVRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARVHGARSAMPMHQARRLVGAPAVVLPPRGVV
YGLASRRVFDTVRTLVPVLEQLSFDEAFGEPQELAGASAADVEEFCELLRARVLEETGLVASVGAGSGKQIAKIASGLAK
PDGIRVVRRADERRLLDSLAVRKLWGIGPVAEDKLHRLGIETIGQLAALSEAEVADILGATVGPALHRLARGIDERPVAE
RAEAKQISAESTFPADLITLDQVREAIGPIADHAHRRLAKDGRGARTVTVKLKKSDMSTLTRSATLPSATTDAATLSATA
RRLLVDPVEIGPIRLVGVGFSGLSEVRQESLFPDLELVEDEPATRPAVPMSVSEAAAVPPAWRVGDDVAHPELGHGWIQG
AGHGVMTIRFETRSTGPGPAKTFPDTVPDVVRANPVDSLDWADYVDALPQADLP
>Mature_454_residues
MDVRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARVHGARSAMPMHQARRLVGAPAVVLPPRGVV
YGLASRRVFDTVRTLVPVLEQLSFDEAFGEPQELAGASAADVEEFCELLRARVLEETGLVASVGAGSGKQIAKIASGLAK
PDGIRVVRRADERRLLDSLAVRKLWGIGPVAEDKLHRLGIETIGQLAALSEAEVADILGATVGPALHRLARGIDERPVAE
RAEAKQISAESTFPADLITLDQVREAIGPIADHAHRRLAKDGRGARTVTVKLKKSDMSTLTRSATLPSATTDAATLSATA
RRLLVDPVEIGPIRLVGVGFSGLSEVRQESLFPDLELVEDEPATRPAVPMSVSEAAAVPPAWRVGDDVAHPELGHGWIQG
AGHGVMTIRFETRSTGPGPAKTFPDTVPDVVRANPVDSLDWADYVDALPQADLP

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=339, Percent_Identity=26.2536873156342, Blast_Score=123, Evalue=4e-28,
Organism=Homo sapiens, GI7706681, Length=340, Percent_Identity=26.1764705882353, Blast_Score=122, Evalue=6e-28,
Organism=Homo sapiens, GI5729982, Length=266, Percent_Identity=27.0676691729323, Blast_Score=85, Evalue=1e-16,
Organism=Homo sapiens, GI7705344, Length=252, Percent_Identity=26.5873015873016, Blast_Score=76, Evalue=6e-14,
Organism=Escherichia coli, GI1786425, Length=348, Percent_Identity=32.4712643678161, Blast_Score=128, Evalue=8e-31,
Organism=Escherichia coli, GI1787432, Length=299, Percent_Identity=28.0936454849498, Blast_Score=97, Evalue=3e-21,
Organism=Caenorhabditis elegans, GI17537959, Length=450, Percent_Identity=24.6666666666667, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI193205702, Length=224, Percent_Identity=32.5892857142857, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI193205700, Length=224, Percent_Identity=32.5892857142857, Blast_Score=75, Evalue=8e-14,
Organism=Drosophila melanogaster, GI19923006, Length=440, Percent_Identity=25.6818181818182, Blast_Score=127, Evalue=2e-29,
Organism=Drosophila melanogaster, GI21355641, Length=330, Percent_Identity=24.5454545454545, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24644984, Length=330, Percent_Identity=24.5454545454545, Blast_Score=81, Evalue=2e-15,
Organism=Drosophila melanogaster, GI24668444, Length=302, Percent_Identity=25.1655629139073, Blast_Score=76, Evalue=4e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 48291; Mature: 48291

Theoretical pI: Translated: 6.04; Mature: 6.04

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
1.8 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARVHGARSAMPM
CCCEEEEEECHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEECCCCHHHHCCCHHCCCH
HQARRLVGAPAVVLPPRGVVYGLASRRVFDTVRTLVPVLEQLSFDEAFGEPQELAGASAA
HHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHCCCCCC
DVEEFCELLRARVLEETGLVASVGAGSGKQIAKIASGLAKPDGIRVVRRADERRLLDSLA
CHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VRKLWGIGPVAEDKLHRLGIETIGQLAALSEAEVADILGATVGPALHRLARGIDERPVAE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RAEAKQISAESTFPADLITLDQVREAIGPIADHAHRRLAKDGRGARTVTVKLKKSDMSTL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHH
TRSATLPSATTDAATLSATARRLLVDPVEIGPIRLVGVGFSGLSEVRQESLFPDLELVED
HHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEECC
EPATRPAVPMSVSEAAAVPPAWRVGDDVAHPELGHGWIQGAGHGVMTIRFETRSTGPGPA
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCCCCCC
KTFPDTVPDVVRANPVDSLDWADYVDALPQADLP
CCCCCCHHHHHHCCCCCCCCHHHHHHHCCCCCCC
>Mature Secondary Structure
MDVRWVLHLDMDAFFASVEQLTRPTLRGRPVLVGGLGGRGVVAGASYEARVHGARSAMPM
CCCEEEEEECHHHHHHHHHHHHCCCCCCCCEEEECCCCCCEEECCCCHHHHCCCHHCCCH
HQARRLVGAPAVVLPPRGVVYGLASRRVFDTVRTLVPVLEQLSFDEAFGEPQELAGASAA
HHHHHHHCCCEEEECCCCCEEHHHHHHHHHHHHHHHHHHHHHCHHHHCCCHHHHCCCCCC
DVEEFCELLRARVLEETGLVASVGAGSGKQIAKIASGLAKPDGIRVVRRADERRLLDSLA
CHHHHHHHHHHHHHHHCCCEEEECCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHH
VRKLWGIGPVAEDKLHRLGIETIGQLAALSEAEVADILGATVGPALHRLARGIDERPVAE
HHHHHCCCCCHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RAEAKQISAESTFPADLITLDQVREAIGPIADHAHRRLAKDGRGARTVTVKLKKSDMSTL
HHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEEECCHHHHH
TRSATLPSATTDAATLSATARRLLVDPVEIGPIRLVGVGFSGLSEVRQESLFPDLELVED
HHHCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEEEECCHHHHHHHHHHCCCCCEEECC
EPATRPAVPMSVSEAAAVPPAWRVGDDVAHPELGHGWIQGAGHGVMTIRFETRSTGPGPA
CCCCCCCCCCCCHHHHCCCCCCCCCCCCCCCCCCCHHHCCCCCEEEEEEEECCCCCCCCC
KTFPDTVPDVVRANPVDSLDWADYVDALPQADLP
CCCCCCHHHHHHCCCCCCCCHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]