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The map label for this gene is secY

Identifier: 161353774

GI number: 161353774

Start: 119728

End: 121101

Strand: Direct

Name: secY

Synonym: CP0118

Alternate gene names: 161353774

Gene position: 119728-121101 (Clockwise)

Preceding gene: 16752410

Following gene: 16752412

Centisome position: 9.74

GC content: 39.74

Gene sequence:

>1374_bases
ATGACCACATTGAGACAATTTTTTCTGATTACCGAATTACGACAAAAGTTATTCTATACTTTTGCTTTGCTTACGGCCTG
TAGAGTGGGTGTATTTATTCCTGTTCCAGGAATTAATGGTGAATTAGCTGTAGCTTACTTCAAGCAGTTATTGGGATCAG
GTCAGAATTTATTTCAACTAGCTGATATTTTTTCTGGAGGCGCTTTTGCCCAAATGACCGTAATTGCGCTGGGTGTGGTT
CCTTACATTTCAGCCTCAATTATCGTTCAGCTGTTCCTAGTCTTTATGCCTGCGCTGCAAAGAGAAATGAGGGAGTCTTC
TGATCAAGGGAAACGTAGGATTGGTAGACTCACACGTTTGTTTACCGTTGCTTTAGCTGTAATACAGTCTCTCTTATTTG
CTAAGTTTGCTCTTAGAATGAATCTAACTATTCCGGGGATTGTTCTGCCCACTTTATTATCTTCAAAACTATTTGGAGTC
CCCTGGATTTTTTATATCACTACAGTTGTAGTCATGACTACAGGAACTCTCTTATTGATGTGGATCGGTGAACAGATCTC
CGATAAGGGGATTGGGAACGGGATAAGTTTAATTATCGCCCTTGGAATTCTATCCTCATTTCCTTCTGTATTGGGATCTA
TTGTTAATAAGTTAAATTTAGGATCTCAAGACTCCTCTGATTTGGGTCTAATTTCAATTTTAATCCTTGCTCTTGTTTTT
GTTTTTGTTCTGATTACTACGATTTTGATTATCGAGGGAGTGAGAAAAATCCCTGTGCAATATGCTCGAAGGGTAATTGG
AAGAAGAGAAGTCCCCGGTGGAGGGTCCTATCTTCCTTTAAAAGTTAACTATGCTGGCGTCATTCCTGTGATTTTTGCTT
CCTCGCTACTGATGTTCCCAGCAACTATAGGACAGTTTATTGCGTCAGAGTCTTCTTGGATGAAGCGTATAGCAGCTTTA
CTTGCTCCAGGCAGTTTAGTTTATTCTATATGTTATGTGTTGCTCATTATATTTTTTACATACTTTTGGACAGCCACACA
ATTTCATCCAGAACAAATTGCTTCTGAAATGAAAAAAAATAATGCCTTTATTCCTGGCATACGTCAGGGCAAGCCTACGC
AACATTACTTAGAGTATACAATGAATCGTGTGACCCTTTTAGGAGCGTTGTTCTTAGCGGCGATCGCGATATTACCTTCA
CTTTTAGGTTGTCTGCTTCGTGTGGATTCTAATGTAAGCTATTTCTTAGGCGGTACTGCAATGCTTATCGTCGTAGGGGT
CGTTTTAGATACAATGAAGCAGGTTGATGCCTTTTTGTTAATGCGTCGCTACGATAGCGTGCTGAAAACAGATCGGACGA
AAGGAAGACATTGA

Upstream 100 bases:

>100_bases
GGAAAAGACTTTTGTATGGCAAGATACTGCTGTAGTCCTATCGCAAGGAGTACAAAATTTGCTAGGCATTACTTAAAAAA
TAAGATTGTTTAGGCCGTAT

Downstream 100 bases:

>100_bases
AAAATAACAATTTTTGACCTAAGATGCTTATACTATTTTAAGGGAGGCCCAACGTATGCCACGCATCATTGGAATTGATA
TTCCTGCAAAGAAAAAGTTA

Product: preprotein translocase subunit SecY

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 457; Mature: 456

Protein sequence:

>457_residues
MTTLRQFFLITELRQKLFYTFALLTACRVGVFIPVPGINGELAVAYFKQLLGSGQNLFQLADIFSGGAFAQMTVIALGVV
PYISASIIVQLFLVFMPALQREMRESSDQGKRRIGRLTRLFTVALAVIQSLLFAKFALRMNLTIPGIVLPTLLSSKLFGV
PWIFYITTVVVMTTGTLLLMWIGEQISDKGIGNGISLIIALGILSSFPSVLGSIVNKLNLGSQDSSDLGLISILILALVF
VFVLITTILIIEGVRKIPVQYARRVIGRREVPGGGSYLPLKVNYAGVIPVIFASSLLMFPATIGQFIASESSWMKRIAAL
LAPGSLVYSICYVLLIIFFTYFWTATQFHPEQIASEMKKNNAFIPGIRQGKPTQHYLEYTMNRVTLLGALFLAAIAILPS
LLGCLLRVDSNVSYFLGGTAMLIVVGVVLDTMKQVDAFLLMRRYDSVLKTDRTKGRH

Sequences:

>Translated_457_residues
MTTLRQFFLITELRQKLFYTFALLTACRVGVFIPVPGINGELAVAYFKQLLGSGQNLFQLADIFSGGAFAQMTVIALGVV
PYISASIIVQLFLVFMPALQREMRESSDQGKRRIGRLTRLFTVALAVIQSLLFAKFALRMNLTIPGIVLPTLLSSKLFGV
PWIFYITTVVVMTTGTLLLMWIGEQISDKGIGNGISLIIALGILSSFPSVLGSIVNKLNLGSQDSSDLGLISILILALVF
VFVLITTILIIEGVRKIPVQYARRVIGRREVPGGGSYLPLKVNYAGVIPVIFASSLLMFPATIGQFIASESSWMKRIAAL
LAPGSLVYSICYVLLIIFFTYFWTATQFHPEQIASEMKKNNAFIPGIRQGKPTQHYLEYTMNRVTLLGALFLAAIAILPS
LLGCLLRVDSNVSYFLGGTAMLIVVGVVLDTMKQVDAFLLMRRYDSVLKTDRTKGRH
>Mature_456_residues
TTLRQFFLITELRQKLFYTFALLTACRVGVFIPVPGINGELAVAYFKQLLGSGQNLFQLADIFSGGAFAQMTVIALGVVP
YISASIIVQLFLVFMPALQREMRESSDQGKRRIGRLTRLFTVALAVIQSLLFAKFALRMNLTIPGIVLPTLLSSKLFGVP
WIFYITTVVVMTTGTLLLMWIGEQISDKGIGNGISLIIALGILSSFPSVLGSIVNKLNLGSQDSSDLGLISILILALVFV
FVLITTILIIEGVRKIPVQYARRVIGRREVPGGGSYLPLKVNYAGVIPVIFASSLLMFPATIGQFIASESSWMKRIAALL
APGSLVYSICYVLLIIFFTYFWTATQFHPEQIASEMKKNNAFIPGIRQGKPTQHYLEYTMNRVTLLGALFLAAIAILPSL
LGCLLRVDSNVSYFLGGTAMLIVVGVVLDTMKQVDAFLLMRRYDSVLKTDRTKGRH

Specific function: Involved in protein export. Interacts with secA and secE to allow the translocation of proteins across the plasma membrane, by forming part of a channel

COG id: COG0201

COG function: function code U; Preprotein translocase subunit SecY

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secY/SEC61-alpha family

Homologues:

Organism=Escherichia coli, GI1789696, Length=446, Percent_Identity=38.3408071748879, Blast_Score=275, Evalue=3e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SECY_CHLPN (Q9Z7S5)

Other databases:

- EMBL:   AE001363
- EMBL:   AE002161
- EMBL:   BA000008
- EMBL:   AE009440
- PIR:   B81613
- PIR:   B86569
- PIR:   G72053
- RefSeq:   NP_224825.1
- RefSeq:   NP_300685.1
- RefSeq:   NP_444670.2
- RefSeq:   NP_876927.1
- ProteinModelPortal:   Q9Z7S5
- GeneID:   1467334
- GeneID:   895464
- GeneID:   919394
- GeneID:   963014
- GenomeReviews:   AE001363_GR
- GenomeReviews:   AE002161_GR
- GenomeReviews:   AE009440_GR
- GenomeReviews:   BA000008_GR
- KEGG:   cpa:CP0118
- KEGG:   cpn:CPn0629
- KEGG:   cpt:CpB0655
- TIGR:   CP_0118
- HOGENOM:   HBG565931
- OMA:   FAQSIMF
- ProtClustDB:   PRK09204
- BioCyc:   CPNE115711:CP_0118-MONOMER
- BioCyc:   CPNE115713:CPN0629-MONOMER
- BioCyc:   CPNE138677:CPJ0629-MONOMER
- BioCyc:   CPNE182082:CPB0655-MONOMER
- InterPro:   IPR002208
- InterPro:   IPR023201
- PANTHER:   PTHR10906
- PIRSF:   PIRSF004557
- PRINTS:   PR00303
- TIGRFAMs:   TIGR00967

Pfam domain/function: PF00344 SecY; SSF103491 SecY

EC number: NA

Molecular weight: Translated: 50287; Mature: 50156

Theoretical pI: Translated: 10.40; Mature: 10.40

Prosite motif: PS00755 SECY_1; PS00756 SECY_2; PS00013 PROKAR_LIPOPROTEIN ; PS00307 LECTIN_LEGUME_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0xb29af48)-; HASH(0x403acac4)-; HASH(0x403a70f4)-; HASH(0xb77d888)-; HASH(0xbf765d4)-; HASH(0xc3e4508)-; HASH(0xbaf9f78)-; HASH(0xb7babb0)-; HASH(0x4039dea8)-; HASH(0x403c6db0)-;

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLRQFFLITELRQKLFYTFALLTACRVGVFIPVPGINGELAVAYFKQLLGSGQNLFQL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHCCCCHHHHH
ADIFSGGAFAQMTVIALGVVPYISASIIVQLFLVFMPALQREMRESSDQGKRRIGRLTRL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTVALAVIQSLLFAKFALRMNLTIPGIVLPTLLSSKLFGVPWIFYITTVVVMTTGTLLLM
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
WIGEQISDKGIGNGISLIIALGILSSFPSVLGSIVNKLNLGSQDSSDLGLISILILALVF
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
VFVLITTILIIEGVRKIPVQYARRVIGRREVPGGGSYLPLKVNYAGVIPVIFASSLLMFP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
ATIGQFIASESSWMKRIAALLAPGSLVYSICYVLLIIFFTYFWTATQFHPEQIASEMKKN
HHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
NAFIPGIRQGKPTQHYLEYTMNRVTLLGALFLAAIAILPSLLGCLLRVDSNVSYFLGGTA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
MLIVVGVVLDTMKQVDAFLLMRRYDSVLKTDRTKGRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH
>Mature Secondary Structure 
TTLRQFFLITELRQKLFYTFALLTACRVGVFIPVPGINGELAVAYFKQLLGSGQNLFQL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCEEEECCCCCCCHHHHHHHHHHCCCCHHHHH
ADIFSGGAFAQMTVIALGVVPYISASIIVQLFLVFMPALQREMRESSDQGKRRIGRLTRL
HHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FTVALAVIQSLLFAKFALRMNLTIPGIVLPTLLSSKLFGVPWIFYITTVVVMTTGTLLLM
HHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHH
WIGEQISDKGIGNGISLIIALGILSSFPSVLGSIVNKLNLGSQDSSDLGLISILILALVF
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHH
VFVLITTILIIEGVRKIPVQYARRVIGRREVPGGGSYLPLKVNYAGVIPVIFASSLLMFP
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCHHHHHHHHHHHHHHH
ATIGQFIASESSWMKRIAALLAPGSLVYSICYVLLIIFFTYFWTATQFHPEQIASEMKKN
HHHHHHHHCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHC
NAFIPGIRQGKPTQHYLEYTMNRVTLLGALFLAAIAILPSLLGCLLRVDSNVSYFLGGTA
CCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHH
MLIVVGVVLDTMKQVDAFLLMRRYDSVLKTDRTKGRH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10192388; 10684935; 10871362