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The map label for this gene is minC

Identifier: 161353743

GI number: 161353743

Start: 4166141

End: 4167034

Strand: Direct

Name: minC

Synonym: alr3455

Alternate gene names: 161353743

Gene position: 4166141-4167034 (Clockwise)

Preceding gene: 17230946

Following gene: 17230948

Centisome position: 64.96

GC content: 46.09

Gene sequence:

>894_bases
ATGGTGGATGAGCAGGTCAATTCTGCACCTGCTCATATCAACTTACCCGACCTCGACTTAGATTTAGAACCAATTTCTCC
GGCGACAGATGTAAACTCTAACTCTGGTTGGTTGAGTCTGAATTCTCCTGAGTCAGTGGTGGATAATAAAGTCAAAAATA
ATATCCAAGTACAATTAAAAACAGAAGCTGGACGACTATTAGTAGTTTTACCTACCGAATTACAAGTACCTGCAACCGAA
TTTACTTGGTCTGATATCTGGCAACAATTGAAGTTCCGTTTAAATGCGGGCGATCGCCTCCGTACCCGGAACACAACCGT
ACACCTAGTAGCATACGATCGCCTGTTAGATGGTAGGCAACTGCAACAACTCGCGGAAACCTTTAGTGAAGTGCAACTGC
AACTCAAATCTGTTGCTACCAGTCGCCGACAAACGGCGATCGCGGCCGTCACATCCGGTTATTCTGTAGAACAATTACAA
CCAGAAACCATCCTCAGTTCGGAACCGAAAGCAACTTCCACACCCCAAGCCGACGCTCTGTATCTGGAAATGACCATCCG
TTCTGGAGTGGAAATTCGTCACCCAGGCACAGTAATTTTATTGGGAGATATCAATCCAGGTGGTATCGTAGTGGCAGATG
GCGACATTCTGGTGTGGGGTCGTCTGCGGGGAATCGCTCATGCAGGGGCTGGGGGTAATCGTGATTGTCTCATCATGTCC
CTGCAAATGGAACCAACCCAATTGCGTATCGCTGATGCTGTAGCTAGAGCGCCAGAAAAATCACCGACGCACTTTTTCCC
CGAAGTAGCACATATTACTTCACAAGGAATACGTATCGTCAGATCTACTGATTTTTCTAGAAACCAAATAAGTAAGATCA
ATCAGACACCATAA

Upstream 100 bases:

>100_bases
TGCAGAATCTAACTCGGTGATTCCTGATGCGGAACTAAATTCTGTTCTTCAGTACTTAAAGTTAAATGCTGAAGTTACTA
ATGTCGAGTCCGATGCGCCA

Downstream 100 bases:

>100_bases
ATATTTAAGATATTTGTCTAACCATAAATCCAGCACATAGTTATCATGACTCGCATTATTGTAATTACCTCCGGTAAAGG
AGGGGTGGGTAAAACTACAG

Product: septum formation inhibitor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 297; Mature: 297

Protein sequence:

>297_residues
MVDEQVNSAPAHINLPDLDLDLEPISPATDVNSNSGWLSLNSPESVVDNKVKNNIQVQLKTEAGRLLVVLPTELQVPATE
FTWSDIWQQLKFRLNAGDRLRTRNTTVHLVAYDRLLDGRQLQQLAETFSEVQLQLKSVATSRRQTAIAAVTSGYSVEQLQ
PETILSSEPKATSTPQADALYLEMTIRSGVEIRHPGTVILLGDINPGGIVVADGDILVWGRLRGIAHAGAGGNRDCLIMS
LQMEPTQLRIADAVARAPEKSPTHFFPEVAHITSQGIRIVRSTDFSRNQISKINQTP

Sequences:

>Translated_297_residues
MVDEQVNSAPAHINLPDLDLDLEPISPATDVNSNSGWLSLNSPESVVDNKVKNNIQVQLKTEAGRLLVVLPTELQVPATE
FTWSDIWQQLKFRLNAGDRLRTRNTTVHLVAYDRLLDGRQLQQLAETFSEVQLQLKSVATSRRQTAIAAVTSGYSVEQLQ
PETILSSEPKATSTPQADALYLEMTIRSGVEIRHPGTVILLGDINPGGIVVADGDILVWGRLRGIAHAGAGGNRDCLIMS
LQMEPTQLRIADAVARAPEKSPTHFFPEVAHITSQGIRIVRSTDFSRNQISKINQTP
>Mature_297_residues
MVDEQVNSAPAHINLPDLDLDLEPISPATDVNSNSGWLSLNSPESVVDNKVKNNIQVQLKTEAGRLLVVLPTELQVPATE
FTWSDIWQQLKFRLNAGDRLRTRNTTVHLVAYDRLLDGRQLQQLAETFSEVQLQLKSVATSRRQTAIAAVTSGYSVEQLQ
PETILSSEPKATSTPQADALYLEMTIRSGVEIRHPGTVILLGDINPGGIVVADGDILVWGRLRGIAHAGAGGNRDCLIMS
LQMEPTQLRIADAVARAPEKSPTHFFPEVAHITSQGIRIVRSTDFSRNQISKINQTP

Specific function: Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize ftsZ filaments that have formed before they mature into polar Z rings. Prevents ftsZ polymerization

COG id: COG0850

COG function: function code D; Septum formation inhibitor

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the minC family

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MINC_NOSS1 (Q8YRJ1)

Other databases:

- EMBL:   BA000019
- PIR:   AH2237
- RefSeq:   NP_487495.2
- ProteinModelPortal:   Q8YRJ1
- STRING:   Q8YRJ1
- GeneID:   1107053
- GenomeReviews:   BA000019_GR
- KEGG:   ana:alr3455
- NMPDR:   fig|103690.1.peg.3762
- eggNOG:   COG0850
- HOGENOM:   HBG399077
- OMA:   SGVEIRH
- ProtClustDB:   PRK00513
- BioCyc:   NSP103690:ALR3455-MONOMER
- HAMAP:   MF_00267
- InterPro:   IPR016098
- InterPro:   IPR013033
- InterPro:   IPR005526
- Gene3D:   G3DSA:2.160.20.70
- TIGRFAMs:   TIGR01222

Pfam domain/function: PF03775 MinC_C; SSF63848 MinC_C

EC number: NA

Molecular weight: Translated: 32579; Mature: 32579

Theoretical pI: Translated: 5.65; Mature: 5.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MVDEQVNSAPAHINLPDLDLDLEPISPATDVNSNSGWLSLNSPESVVDNKVKNNIQVQLK
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCEEEEEE
TEAGRLLVVLPTELQVPATEFTWSDIWQQLKFRLNAGDRLRTRNTTVHLVAYDRLLDGRQ
ECCCCEEEEECCCCCCCCCCCCHHHHHHHHHEECCCCCEEEECCCEEEEEEECCCCCCHH
LQQLAETFSEVQLQLKSVATSRRQTAIAAVTSGYSVEQLQPETILSSEPKATSTPQADAL
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHCCCHHHHCCCCCCCCCCCCCEE
YLEMTIRSGVEIRHPGTVILLGDINPGGIVVADGDILVWGRLRGIAHAGAGGNRDCLIMS
EEEEEECCCEEEECCCEEEEEECCCCCCEEEECCCEEEEEEECEEEECCCCCCCCEEEEE
LQMEPTQLRIADAVARAPEKSPTHFFPEVAHITSQGIRIVRSTDFSRNQISKINQTP
EECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEECCCCHHHHHHCCCCC
>Mature Secondary Structure
MVDEQVNSAPAHINLPDLDLDLEPISPATDVNSNSGWLSLNSPESVVDNKVKNNIQVQLK
CCCCCCCCCCCEEECCCCCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHCCCEEEEEE
TEAGRLLVVLPTELQVPATEFTWSDIWQQLKFRLNAGDRLRTRNTTVHLVAYDRLLDGRQ
ECCCCEEEEECCCCCCCCCCCCHHHHHHHHHEECCCCCEEEECCCEEEEEEECCCCCCHH
LQQLAETFSEVQLQLKSVATSRRQTAIAAVTSGYSVEQLQPETILSSEPKATSTPQADAL
HHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCHHHCCCHHHHCCCCCCCCCCCCCEE
YLEMTIRSGVEIRHPGTVILLGDINPGGIVVADGDILVWGRLRGIAHAGAGGNRDCLIMS
EEEEEECCCEEEECCCEEEEEECCCCCCEEEECCCEEEEEEECEEEECCCCCCCCEEEEE
LQMEPTQLRIADAVARAPEKSPTHFFPEVAHITSQGIRIVRSTDFSRNQISKINQTP
EECCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHCCEEEEEECCCCHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11759840