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The map label for this gene is bioD [H]

Identifier: 161353736

GI number: 161353736

Start: 5566388

End: 5567065

Strand: Reverse

Name: bioD [H]

Synonym: all4667

Alternate gene names: 161353736

Gene position: 5567065-5566388 (Counterclockwise)

Preceding gene: 17232160

Following gene: 17232158

Centisome position: 86.8

GC content: 43.07

Gene sequence:

>678_bases
TTGTTGAAGTCACTACTAATTACTGGAACTGATACAGAAGCTGGCAAAACTGCTCTGACTACAGTTTTGGCAGCTTACTG
TCAGAAATATTACCCCCAAGGCAGTTGGGGAATTATGAAACCAATTCAATCGGGAATTGGCGATCGCGAATGGTATCAAA
ATCTGTTTACACTAGAGCAAACGATCGCCGAAATTACACCTCTGCACTTTAGCGCACCTCTAGCTCCTCCCATCGCCGCC
GCCAAGGAAAATCGTTCCGTCGATTTAGCTATAGTTTGGCAGACTTTAACCCAGTTGCGATCGCGTCTTGATGTGTTGTT
AATTGAAGCTTTAGGTGGGTTAGGTTCACCAGTCACCGACGAGTTAACAGTGGCTGATTTAGCCGGAGAATGGCGCTTAC
CCACAGTATTAGTAGTACCAGTAAAATTAGGTTCACTAGGACAGGTTGTAGCGAATGTAGCATTGGCTAGACAAGCGCGG
GTGGATCTCAAAGGGATTGTGTTGAACTGTACACAACCTCTATCTGATGAAGAAATTGCCGACTTAACACCAAAAGATTT
AATTCAATCCCTCACGAATATTCCAGTTTTAGGCTGTCTACCTTATATAGATAACTTCTCTGATTTCGATAAACTGGTGC
AAATCGCCTCAAATTTAGATTTAGAAACGCTGAAGTAA

Upstream 100 bases:

>100_bases
CAGTGTATTACAATATCTGTGAGTTCTTAACGATCAAAACTCGGAAGTAATGCGATTTACTTCATCACTTACCCGTCTTC
ATTCAGATTATTAAACCAGA

Downstream 100 bases:

>100_bases
GTAAGTTTAAGGGTGTAAGGGTTTAGGGGTGTATGGGTGTATGGGTTAGTCAAATGATGATTCTCTCATTAGTTTGAGCG
TCACAATTTACCGCTTGCTA

Product: dithiobiotin synthetase

Products: NA

Alternate protein names: DTB synthetase; DTBS; Dethiobiotin synthase [H]

Number of amino acids: Translated: 225; Mature: 225

Protein sequence:

>225_residues
MLKSLLITGTDTEAGKTALTTVLAAYCQKYYPQGSWGIMKPIQSGIGDREWYQNLFTLEQTIAEITPLHFSAPLAPPIAA
AKENRSVDLAIVWQTLTQLRSRLDVLLIEALGGLGSPVTDELTVADLAGEWRLPTVLVVPVKLGSLGQVVANVALARQAR
VDLKGIVLNCTQPLSDEEIADLTPKDLIQSLTNIPVLGCLPYIDNFSDFDKLVQIASNLDLETLK

Sequences:

>Translated_225_residues
MLKSLLITGTDTEAGKTALTTVLAAYCQKYYPQGSWGIMKPIQSGIGDREWYQNLFTLEQTIAEITPLHFSAPLAPPIAA
AKENRSVDLAIVWQTLTQLRSRLDVLLIEALGGLGSPVTDELTVADLAGEWRLPTVLVVPVKLGSLGQVVANVALARQAR
VDLKGIVLNCTQPLSDEEIADLTPKDLIQSLTNIPVLGCLPYIDNFSDFDKLVQIASNLDLETLK
>Mature_225_residues
MLKSLLITGTDTEAGKTALTTVLAAYCQKYYPQGSWGIMKPIQSGIGDREWYQNLFTLEQTIAEITPLHFSAPLAPPIAA
AKENRSVDLAIVWQTLTQLRSRLDVLLIEALGGLGSPVTDELTVADLAGEWRLPTVLVVPVKLGSLGQVVANVALARQAR
VDLKGIVLNCTQPLSDEEIADLTPKDLIQSLTNIPVLGCLPYIDNFSDFDKLVQIASNLDLETLK

Specific function: Bioconversion of pimelate into dethiobiotin. [C]

COG id: COG0132

COG function: function code H; Dethiobiotin synthetase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dethiobiotin synthetase family [H]

Homologues:

Organism=Escherichia coli, GI1786995, Length=214, Percent_Identity=29.9065420560748, Blast_Score=86, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004472 [H]

Pfam domain/function: NA

EC number: =6.3.3.3 [H]

Molecular weight: Translated: 24424; Mature: 24424

Theoretical pI: Translated: 4.41; Mature: 4.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLKSLLITGTDTEAGKTALTTVLAAYCQKYYPQGSWGIMKPIQSGIGDREWYQNLFTLEQ
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
TIAEITPLHFSAPLAPPIAAAKENRSVDLAIVWQTLTQLRSRLDVLLIEALGGLGSPVTD
HHHHHCCCCCCCCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ELTVADLAGEWRLPTVLVVPVKLGSLGQVVANVALARQARVDLKGIVLNCTQPLSDEEIA
CHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHH
DLTPKDLIQSLTNIPVLGCLPYIDNFSDFDKLVQIASNLDLETLK
CCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MLKSLLITGTDTEAGKTALTTVLAAYCQKYYPQGSWGIMKPIQSGIGDREWYQNLFTLEQ
CCCCEEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHCCCHHHHHHHHHHHHH
TIAEITPLHFSAPLAPPIAAAKENRSVDLAIVWQTLTQLRSRLDVLLIEALGGLGSPVTD
HHHHHCCCCCCCCCCCCHHHHCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCC
ELTVADLAGEWRLPTVLVVPVKLGSLGQVVANVALARQARVDLKGIVLNCTQPLSDEEIA
CHHHHHHCCCCCCCEEEEEECCCCHHHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCHHH
DLTPKDLIQSLTNIPVLGCLPYIDNFSDFDKLVQIASNLDLETLK
CCCHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA