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The map label for this gene is secD

Identifier: 161353436

GI number: 161353436

Start: 1629255

End: 1630832

Strand: Reverse

Name: secD

Synonym: HP1550

Alternate gene names: 161353436

Gene position: 1630832-1629255 (Counterclockwise)

Preceding gene: 15646158

Following gene: 15646156

Centisome position: 97.78

GC content: 43.28

Gene sequence:

>1578_bases
ATGAAACTTTTTAACGCTCGTTTAATCGTTTTTATTGGCGCGCTTCTTTTAGGGGTAGGGTTTTCTGTGCCTTCTTTACT
AGAAACTAAAGGCCCTAAAATCACTTTAGGTTTGGATTTAAGGGGGGGGTTGAACATGCTTTTAGGGGTACAAACCGATG
AGGCTTTAAAAAACAAGTATTTAAGCTTGGCGTCCGCTTTAGAATACAACGCTAAAAAGCAAAATATCTTGCTTAAAGAT
ATTAAATCCAATTTAGAAGGGATCAGTTTTGAGCTTTTAGATGAAGATGAAGCGAAAAAATTAGACGCGCTTTTATTGGA
ATTGCAAGGCCATAGCCAGTTTGAAATCAAAAAGGAAGCGGGGTTTTATAGCGTGAATCTCACCCCTTTAGAGCAAGAAG
AATTGCGTAAAAACACGATTTTGCAAGTGATAGGGATCATTCGTAACCGCTTGGATCAATTTGGTTTGGCAGAGCCTGTA
GTCATTCAGCAAGGTAAAGAAGAAATTTCGGTGCAATTGCCTGGCATTAAGACTTTAGAAGAAGAACGGCGCGCTAAAGA
CTTGATTTCAAGATCCGCTCATTTGCAGATGATGGCGGTGGATGAAGAACACAATAAAGATGCGATGAAAATGACGGATT
TAGAGGCTCAAAAATTAGGCAGCGTGTTGTTGTCTGATGTGGAAATGGGGGGTAAAATCTTGCTCAAAGCGATCCCCATT
TTAGATGGCGAAATGCTTACAGATGCGAAAGTGGTGTATGACCAAAACAACCAGCCGGTGGTGAGCTTCACGCTGGATGC
GCAAGGGGCTAAGATTTTTGGGGATTTCTCAGGTGCGAATGTGGGCAAACGCATGGCGATTGTTTTAGACAATAAGGTCT
ATTCAGCCCCGGTGATTAGGGAGCGTATCGGTGGGGGGAGCGGGCAGATTAGCGGGAATTTTAGCGTGGCTCAAGCGAGC
GATTTAGCGATCGCTTTAAGGAGTGGGGCGATGAGCGCTCCCATTCAGGTTTTAGAAAAAAGAATTATAGGCCCAAGTTT
AGGGAAAGACAGCGTTAAAACTTCCATTATCGCTCTAGTTGGGGGCTTTATTTTAGTGATGGGCTTTATGGTGCTTTATT
ACTCTATGGCGGGGGTGATCGCTTGTTTGGCGTTAGTGGTCAATCTTTTTTTGATTGTGGCGGTCATGGCGATTTTTGGA
GCGACGCTGACTTTACCGGGAATGGCGGGGATTGTTTTAACCGTGGGGATTGCCGTGGATGCTAATATCATCATCAACGA
GCGCATTAGAGAAGTCTTAAGAGAGAATGAGGGCATCGCTAAAGCGATCCATTTAGGCTATATCAATGCGAGCCGGGCGA
TTTTTGATTCTAATATCACTTCTTTGATCGCTTCAGTGTTATTATACGCTTATGGCACAGGAGCGATTAAAGGCTTTGCC
CTAACTACAGGCATTGGGATTTTAGCCTCTATTATCACCGCTATTGTTGGCACGCAAGGGATTTATCAAGCCCTTTTACC
TAAACTCACTCAAACAAAAAGCCTTTACTTTTGGTTTGGCGTGAATAAAAGAGCTTAG

Upstream 100 bases:

>100_bases
TTGGTTTGGCAGAGCCTATAGTCATTCAGCAAGGCAGAGAAGAAATTTCGGCAAAATTATCTGGTGCTAAGACTTTGAAA
CAACGCCAAATAACAACTGA

Downstream 100 bases:

>100_bases
GAGGTTTTATGGAATTATTCAAACGAACTAGAATCTTAAGCTTCATGCGTTATTCCAATTATGGGGTGATCGTTTCAGCA
ATTTTAGCGCTTCTAGCGTT

Product: preprotein translocase subunit SecD

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 525; Mature: 525

Protein sequence:

>525_residues
MKLFNARLIVFIGALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKD
IKSNLEGISFELLDEDEAKKLDALLLELQGHSQFEIKKEAGFYSVNLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPV
VIQQGKEEISVQLPGIKTLEEERRAKDLISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGNFSVAQAS
DLAIALRSGAMSAPIQVLEKRIIGPSLGKDSVKTSIIALVGGFILVMGFMVLYYSMAGVIACLALVVNLFLIVAVMAIFG
ATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA

Sequences:

>Translated_525_residues
MKLFNARLIVFIGALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKD
IKSNLEGISFELLDEDEAKKLDALLLELQGHSQFEIKKEAGFYSVNLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPV
VIQQGKEEISVQLPGIKTLEEERRAKDLISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGNFSVAQAS
DLAIALRSGAMSAPIQVLEKRIIGPSLGKDSVKTSIIALVGGFILVMGFMVLYYSMAGVIACLALVVNLFLIVAVMAIFG
ATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA
>Mature_525_residues
MKLFNARLIVFIGALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKYLSLASALEYNAKKQNILLKD
IKSNLEGISFELLDEDEAKKLDALLLELQGHSQFEIKKEAGFYSVNLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPV
VIQQGKEEISVQLPGIKTLEEERRAKDLISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIRERIGGGSGQISGNFSVAQAS
DLAIALRSGAMSAPIQVLEKRIIGPSLGKDSVKTSIIALVGGFILVMGFMVLYYSMAGVIACLALVVNLFLIVAVMAIFG
ATLTLPGMAGIVLTVGIAVDANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA

Specific function: Involved in protein export [H]

COG id: COG0342

COG function: function code U; Preprotein translocase subunit SecD

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the secD/secF family. SecD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786609, Length=499, Percent_Identity=37.0741482965932, Blast_Score=285, Evalue=5e-78,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001036
- InterPro:   IPR005791
- InterPro:   IPR022813
- InterPro:   IPR022646
- InterPro:   IPR022645 [H]

Pfam domain/function: PF07549 Sec_GG; PF02355 SecD_SecF [H]

EC number: NA

Molecular weight: Translated: 56578; Mature: 56578

Theoretical pI: Translated: 7.64; Mature: 7.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLFNARLIVFIGALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKY
CCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEEECCCCCCEEEECCCHHHHHHHH
LSLASALEYNAKKQNILLKDIKSNLEGISFELLDEDEAKKLDALLLELQGHSQFEIKKEA
HHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEECC
GFYSVNLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPVVIQQGKEEISVQLPGIKTLE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECCCCHHHH
EERRAKDLISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
HHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIR
CCCCCCCCCEEEEECCCCEEEEEEEECCCCEEEECCCCCCCCCEEEEEECCCCCCCCHHH
ERIGGGSGQISGNFSVAQASDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSVKTSIIALV
HHCCCCCCEECCCEEEECCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
GGFILVMGFMVLYYSMAGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHEEEHHCC
ANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
CCEEEHHHHHHHHHCCCCHHHHHEEEEECCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHH
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCC
>Mature Secondary Structure
MKLFNARLIVFIGALLLGVGFSVPSLLETKGPKITLGLDLRGGLNMLLGVQTDEALKNKY
CCCCHHHHHHHHHHHHHHCCCCCCHHHHCCCCEEEEEEECCCCCCEEEECCCHHHHHHHH
LSLASALEYNAKKQNILLKDIKSNLEGISFELLDEDEAKKLDALLLELQGHSQFEIKKEA
HHHHHHHHCCCCHHHHHHHHHHCCCCCCEEEEECCHHHHHHHHHHHHHCCCCCEEEEECC
GFYSVNLTPLEQEELRKNTILQVIGIIRNRLDQFGLAEPVVIQQGKEEISVQLPGIKTLE
CEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHCCCCCEEEECCCCHHHH
EERRAKDLISRSAHLQMMAVDEEHNKDAMKMTDLEAQKLGSVLLSDVEMGGKILLKAIPI
HHHHHHHHHHCCCCEEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCC
LDGEMLTDAKVVYDQNNQPVVSFTLDAQGAKIFGDFSGANVGKRMAIVLDNKVYSAPVIR
CCCCCCCCCEEEEECCCCEEEEEEEECCCCEEEECCCCCCCCCEEEEEECCCCCCCCHHH
ERIGGGSGQISGNFSVAQASDLAIALRSGAMSAPIQVLEKRIIGPSLGKDSVKTSIIALV
HHCCCCCCEECCCEEEECCCCCEEEECCCCCCCHHHHHHHHHCCCCCCCHHHHHHHHHHH
GGFILVMGFMVLYYSMAGVIACLALVVNLFLIVAVMAIFGATLTLPGMAGIVLTVGIAVD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCHHHHHHEEEHHCC
ANIIINERIREVLRENEGIAKAIHLGYINASRAIFDSNITSLIASVLLYAYGTGAIKGFA
CCEEEHHHHHHHHHCCCCHHHHHEEEEECCCHHHHHCCHHHHHHHHHHHHHCCCHHHHHH
LTTGIGILASIITAIVGTQGIYQALLPKLTQTKSLYFWFGVNKRA
HHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9923682 [H]