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The map label for this gene is pdxH [H]

Identifier: 161350023

GI number: 161350023

Start: 913819

End: 914451

Strand: Direct

Name: pdxH [H]

Synonym: HI0863

Alternate gene names: 161350023

Gene position: 913819-914451 (Clockwise)

Preceding gene: 16272799

Following gene: 16272805

Centisome position: 49.93

GC content: 42.34

Gene sequence:

>633_bases
ATGGAGTTACACAATATTCGTGATGAATATACTAAACGAGTGCTTTCACAACATGATTGCCATGAAAATCCAATTTCGCA
ATTTGAACAGTGGCAGAAAGAGGCTATTCATGCTCAAGTCAATGAGCCAACCGCAATGAATATTGCGACTGTTGATGAAC
AAGGTCGCCCAAATAGCCGAATGGTTTTGTTAAAAGAAGTCAATGAGCAAGGTTTTGTCTTTTTTACCAATTATCTTAGT
CGAAAAGGCGGCTGTATTGAGCACAATCCTTATGTCGCGCTGACTTTCTTTTGGCCTGAATTGGAACGCCAAGTGCGGAT
TGAAGGTAAGGCGGTTAAAATTCCAGCAGAACAATCCGATAAATATTTTGCTACCCGACCTTACACCAGTCGTATAGGAG
CTTGGGCAAGTGAGCAAAGTGCAGTGATTTCTAATTATAAATCTTTGTTAGCAAAAGCCGCATTGGTTGCCGCTAAACAT
CCGTTAAACGTGCCGCGCCCAGATTATTGGGGCGGCTATTTAGTCGTGCCAGAAACCGTGGAATTTTGGCAGGGGCGTCC
AAGCCGTTTACATGATCGCATTCGTTATCGTAAAGAAAGTGATAATTGGATTAGAGAAAGACTTTCTCCTTAG

Upstream 100 bases:

>100_bases
GAGTCGATTGCATTTGAGTTTTATATTTTATGAAAATTGACGAATGATTTTACAGCCTTTATTCTATTTGCGTTTTTCAT
CAAATTTGAAAGGAGAGAAA

Downstream 100 bases:

>100_bases
TAAATTGAGAATGAAAATAACCGCACTTTAGTTGTATCCCGAAAGTGCGGTTAATTTTTTCTAAATTTTAGCGTTTAGCT
TTATTTATTAATGCGTGCTA

Product: pyridoxamine 5'-phosphate oxidase

Products: NA

Alternate protein names: PNP/PMP oxidase; PNPOx; Pyridoxal 5'-phosphate synthase [H]

Number of amino acids: Translated: 210; Mature: 210

Protein sequence:

>210_residues
MELHNIRDEYTKRVLSQHDCHENPISQFEQWQKEAIHAQVNEPTAMNIATVDEQGRPNSRMVLLKEVNEQGFVFFTNYLS
RKGGCIEHNPYVALTFFWPELERQVRIEGKAVKIPAEQSDKYFATRPYTSRIGAWASEQSAVISNYKSLLAKAALVAAKH
PLNVPRPDYWGGYLVVPETVEFWQGRPSRLHDRIRYRKESDNWIRERLSP

Sequences:

>Translated_210_residues
MELHNIRDEYTKRVLSQHDCHENPISQFEQWQKEAIHAQVNEPTAMNIATVDEQGRPNSRMVLLKEVNEQGFVFFTNYLS
RKGGCIEHNPYVALTFFWPELERQVRIEGKAVKIPAEQSDKYFATRPYTSRIGAWASEQSAVISNYKSLLAKAALVAAKH
PLNVPRPDYWGGYLVVPETVEFWQGRPSRLHDRIRYRKESDNWIRERLSP
>Mature_210_residues
MELHNIRDEYTKRVLSQHDCHENPISQFEQWQKEAIHAQVNEPTAMNIATVDEQGRPNSRMVLLKEVNEQGFVFFTNYLS
RKGGCIEHNPYVALTFFWPELERQVRIEGKAVKIPAEQSDKYFATRPYTSRIGAWASEQSAVISNYKSLLAKAALVAAKH
PLNVPRPDYWGGYLVVPETVEFWQGRPSRLHDRIRYRKESDNWIRERLSP

Specific function: Catalyzes the oxidation of either pyridoxine 5'- phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP) [H]

COG id: COG0259

COG function: function code H; Pyridoxamine-phosphate oxidase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the pyridoxamine 5'-phosphate oxidase family [H]

Homologues:

Organism=Homo sapiens, GI8922498, Length=230, Percent_Identity=38.695652173913, Blast_Score=166, Evalue=1e-41,
Organism=Escherichia coli, GI1787926, Length=210, Percent_Identity=46.1904761904762, Blast_Score=186, Evalue=8e-49,
Organism=Caenorhabditis elegans, GI17553712, Length=228, Percent_Identity=37.719298245614, Blast_Score=161, Evalue=2e-40,
Organism=Saccharomyces cerevisiae, GI6319509, Length=209, Percent_Identity=42.5837320574163, Blast_Score=164, Evalue=1e-41,
Organism=Drosophila melanogaster, GI45551845, Length=229, Percent_Identity=44.5414847161572, Blast_Score=167, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24644901, Length=229, Percent_Identity=44.5414847161572, Blast_Score=167, Evalue=5e-42,
Organism=Drosophila melanogaster, GI24644903, Length=189, Percent_Identity=31.7460317460317, Blast_Score=88, Evalue=4e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000659
- InterPro:   IPR019740
- InterPro:   IPR019576
- InterPro:   IPR011576
- InterPro:   IPR012349
- InterPro:   IPR009002 [H]

Pfam domain/function: PF10590 PNPOx_C; PF01243 Pyridox_oxidase [H]

EC number: =1.4.3.5 [H]

Molecular weight: Translated: 24500; Mature: 24500

Theoretical pI: Translated: 8.64; Mature: 8.64

Prosite motif: PS00579 RIBOSOMAL_L29 ; PS01064 PYRIDOX_OXIDASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MELHNIRDEYTKRVLSQHDCHENPISQFEQWQKEAIHAQVNEPTAMNIATVDEQGRPNSR
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCE
MVLLKEVNEQGFVFFTNYLSRKGGCIEHNPYVALTFFWPELERQVRIEGKAVKIPAEQSD
EEEEEECCCCCEEEEEEHHHCCCCCEECCCEEEEEEECCCCCCEEEECCEEEECCCCCCC
KYFATRPYTSRIGAWASEQSAVISNYKSLLAKAALVAAKHPLNVPRPDYWGGYLVVPETV
CEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHH
EFWQGRPSRLHDRIRYRKESDNWIRERLSP
HHHCCCHHHHHHHHHHCCCCHHHHHHHCCC
>Mature Secondary Structure
MELHNIRDEYTKRVLSQHDCHENPISQFEQWQKEAIHAQVNEPTAMNIATVDEQGRPNSR
CCCCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCE
MVLLKEVNEQGFVFFTNYLSRKGGCIEHNPYVALTFFWPELERQVRIEGKAVKIPAEQSD
EEEEEECCCCCEEEEEEHHHCCCCCEECCCEEEEEEECCCCCCEEEECCEEEECCCCCCC
KYFATRPYTSRIGAWASEQSAVISNYKSLLAKAALVAAKHPLNVPRPDYWGGYLVVPETV
CEEEECCCHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHH
EFWQGRPSRLHDRIRYRKESDNWIRERLSP
HHHCCCHHHHHHHHHHCCCCHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA