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The map label for this gene is engA [H]

Identifier: 161349991

GI number: 161349991

Start: 1995680

End: 1996993

Strand: Direct

Name: engA [H]

Synonym: ABC1876

Alternate gene names: 161349991

Gene position: 1995680-1996993 (Clockwise)

Preceding gene: 56963640

Following gene: 56963642

Centisome position: 46.37

GC content: 46.27

Gene sequence:

>1314_bases
GTGACTAAACCAGTTGTTGCAATCGTTGGCCGGCCGAATGTAGGGAAGTCAACTATATTTAACCGGATTGTCGGCGAGCG
TGTCGCCATTGTTGAAGACTTACCGGGGGTAACACGTGACCGTTTATATAGCAAAGGCGAATGGCTTAACCACGAATTTT
ATGTAATCGACACAGGCGGAATTGAGCTCGGCGATGAACCGTTGCTCGTGCAAATGCGCCAACAGGCGGAAATTGCTATT
GACGAAGCGAATGTGATTATTTTTATGGTCAATGGACGAGAAGGAATTACTGCCGCAGACCAAGAAGTGGCAAACATGCT
TTTCCGGTCGAAAAAGCCGGTTGTGCTTGCTGTTAATAAAGTTGACAACCCAGATATGAGGGAATTGCTTTACGAGTTCT
ATTCATTAGGGGCGGGTGAGCCTTACGGCATTTCAGGCTCCCACGGATTAGGGATTGGCGACTTGCTTGATGAAGTGGTT
CGCCATTTTCCTGAAGAAAACGACGATGATTATGCAGATGATACGATAAAAATGGCATTGATCGGCCGTCCGAACGTCGG
CAAGTCTTCGCTTGTTAATGCGCTTCTTGGTGAAGAGCGAGTGATCGTCAGCCAAATTCCAGGGACGACCCGTGATGCGA
TTGATACATCCTTTACGCGAGATGGCCAACATTATGTTGTAATTGATACTGCCGGTATGCGGAAGCGTGGCAAAGTTTAT
GAAGCCACTGAAAAATATAGTGTGCTCCGTTCACTCAAGGCGATTGAGCGGTCTGATGTCGTTCTTGTCGTCTTAGATGG
TGAAGAGGGGATTATTGAACAAGATAAAAAAATAGCCGGTTATGCCCATGAAGCGGGAAGGGCAATCGTCATCGTCGTCA
ACAAATGGGACGCCGTAAAAAAAGATGACAAAACGATGCAGACATTTGTCGAAGACATCCGTTCCGAGTTTCAGTTTCTT
TCGTATGCGCCGATTTGTTTTTTGTCCGCCAAGACGAAGCAGCGCCTTCATTTGTTGCTGCCTGAAGTGAGGAAAGTGTC
AGAAAGCCATCATCTTCGTGTGCCGACTCATGTCCTCAATGATATGATTATGGATGCGGTAGCCATGAATCCAACCCCAA
CGGATAAAGGCAAGCGCCTGAAAATCAATTATGTGACGCAAGTGGCCGTACAGCCGCCGACATTCGTGTTCTTTGTAAAC
GAACCTGAACTGATGCATTTCTCTTATAGGCGCTTTTTAGAAAACCGATTGCGTGCTACTTTTGAGTTTGAAGGAACGCC
TATTCACATCATTGCACGGAAAAAGAATGATTAA

Upstream 100 bases:

>100_bases
AAGGATAGACAAGCATGCATGAAGATAGTAAAATGGTTAAGCTGGAGAAGAAAACGAACGCTGTTTTTTAAGTAGTTTGA
AGGAGAAAGGGTGTGTGATT

Downstream 100 bases:

>100_bases
TAATTGGCAAGGGGGAAACTGAATGATCGTTTCATTAATTGCGACGGTGTTGTTCGGTTATTTGCTTGGGTCTGTCAGCT
TTAGCTATATCATTGCGAAG

Product: GTP-binding protein EngA

Products: NA

Alternate protein names: GTP-binding protein EngA [H]

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MTKPVVAIVGRPNVGKSTIFNRIVGERVAIVEDLPGVTRDRLYSKGEWLNHEFYVIDTGGIELGDEPLLVQMRQQAEIAI
DEANVIIFMVNGREGITAADQEVANMLFRSKKPVVLAVNKVDNPDMRELLYEFYSLGAGEPYGISGSHGLGIGDLLDEVV
RHFPEENDDDYADDTIKMALIGRPNVGKSSLVNALLGEERVIVSQIPGTTRDAIDTSFTRDGQHYVVIDTAGMRKRGKVY
EATEKYSVLRSLKAIERSDVVLVVLDGEEGIIEQDKKIAGYAHEAGRAIVIVVNKWDAVKKDDKTMQTFVEDIRSEFQFL
SYAPICFLSAKTKQRLHLLLPEVRKVSESHHLRVPTHVLNDMIMDAVAMNPTPTDKGKRLKINYVTQVAVQPPTFVFFVN
EPELMHFSYRRFLENRLRATFEFEGTPIHIIARKKND

Sequences:

>Translated_437_residues
MTKPVVAIVGRPNVGKSTIFNRIVGERVAIVEDLPGVTRDRLYSKGEWLNHEFYVIDTGGIELGDEPLLVQMRQQAEIAI
DEANVIIFMVNGREGITAADQEVANMLFRSKKPVVLAVNKVDNPDMRELLYEFYSLGAGEPYGISGSHGLGIGDLLDEVV
RHFPEENDDDYADDTIKMALIGRPNVGKSSLVNALLGEERVIVSQIPGTTRDAIDTSFTRDGQHYVVIDTAGMRKRGKVY
EATEKYSVLRSLKAIERSDVVLVVLDGEEGIIEQDKKIAGYAHEAGRAIVIVVNKWDAVKKDDKTMQTFVEDIRSEFQFL
SYAPICFLSAKTKQRLHLLLPEVRKVSESHHLRVPTHVLNDMIMDAVAMNPTPTDKGKRLKINYVTQVAVQPPTFVFFVN
EPELMHFSYRRFLENRLRATFEFEGTPIHIIARKKND
>Mature_436_residues
TKPVVAIVGRPNVGKSTIFNRIVGERVAIVEDLPGVTRDRLYSKGEWLNHEFYVIDTGGIELGDEPLLVQMRQQAEIAID
EANVIIFMVNGREGITAADQEVANMLFRSKKPVVLAVNKVDNPDMRELLYEFYSLGAGEPYGISGSHGLGIGDLLDEVVR
HFPEENDDDYADDTIKMALIGRPNVGKSSLVNALLGEERVIVSQIPGTTRDAIDTSFTRDGQHYVVIDTAGMRKRGKVYE
ATEKYSVLRSLKAIERSDVVLVVLDGEEGIIEQDKKIAGYAHEAGRAIVIVVNKWDAVKKDDKTMQTFVEDIRSEFQFLS
YAPICFLSAKTKQRLHLLLPEVRKVSESHHLRVPTHVLNDMIMDAVAMNPTPTDKGKRLKINYVTQVAVQPPTFVFFVNE
PELMHFSYRRFLENRLRATFEFEGTPIHIIARKKND

Specific function: GTPase that plays an essential role in the late steps of ribosome biogenesis [H]

COG id: COG1160

COG function: function code R; Predicted GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 KH-like domain [H]

Homologues:

Organism=Escherichia coli, GI87082120, Length=455, Percent_Identity=41.7582417582418, Blast_Score=340, Evalue=1e-94,
Organism=Escherichia coli, GI1788919, Length=178, Percent_Identity=32.5842696629214, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI2367268, Length=92, Percent_Identity=43.4782608695652, Blast_Score=75, Evalue=1e-14,
Organism=Caenorhabditis elegans, GI17507259, Length=115, Percent_Identity=35.6521739130435, Blast_Score=74, Evalue=2e-13,
Organism=Saccharomyces cerevisiae, GI6323665, Length=202, Percent_Identity=32.6732673267327, Blast_Score=89, Evalue=1e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016484
- InterPro:   IPR006073
- InterPro:   IPR015946
- InterPro:   IPR002917
- InterPro:   IPR005225 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 49169; Mature: 49038

Theoretical pI: Translated: 6.00; Mature: 6.00

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKPVVAIVGRPNVGKSTIFNRIVGERVAIVEDLPGVTRDRLYSKGEWLNHEFYVIDTGG
CCCCEEEEEECCCCCHHHHHHHHHHHHHEEHHHCCCCHHHHHCCCCCCCCCEEEEEECCC
IELGDEPLLVQMRQQAEIAIDEANVIIFMVNGREGITAADQEVANMLFRSKKPVVLAVNK
CCCCCCHHHHHHHHCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEC
VDNPDMRELLYEFYSLGAGEPYGISGSHGLGIGDLLDEVVRHFPEENDDDYADDTIKMAL
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
IGRPNVGKSSLVNALLGEERVIVSQIPGTTRDAIDTSFTRDGQHYVVIDTAGMRKRGKVY
ECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCCCCEEEEEECCCCCCCCCCH
EATEKYSVLRSLKAIERSDVVLVVLDGEEGIIEQDKKIAGYAHEAGRAIVIVVNKWDAVK
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCHHHCCHHCCCCEEEEEEECCCCCC
KDDKTMQTFVEDIRSEFQFLSYAPICFLSAKTKQRLHLLLPEVRKVSESHHLRVPTHVLN
CCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEECCHHHHH
DMIMDAVAMNPTPTDKGKRLKINYVTQVAVQPPTFVFFVNEPELMHFSYRRFLENRLRAT
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHCEE
FEFEGTPIHIIARKKND
EEECCCEEEEEEECCCC
>Mature Secondary Structure 
TKPVVAIVGRPNVGKSTIFNRIVGERVAIVEDLPGVTRDRLYSKGEWLNHEFYVIDTGG
CCCEEEEEECCCCCHHHHHHHHHHHHHEEHHHCCCCHHHHHCCCCCCCCCEEEEEECCC
IELGDEPLLVQMRQQAEIAIDEANVIIFMVNGREGITAADQEVANMLFRSKKPVVLAVNK
CCCCCCHHHHHHHHCCCEEEECCCEEEEEEECCCCCCHHHHHHHHHHHHCCCCEEEEEEC
VDNPDMRELLYEFYSLGAGEPYGISGSHGLGIGDLLDEVVRHFPEENDDDYADDTIKMAL
CCCCHHHHHHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCEEEEEE
IGRPNVGKSSLVNALLGEERVIVSQIPGTTRDAIDTSFTRDGQHYVVIDTAGMRKRGKVY
ECCCCCCHHHHHHHHHCCCEEEEEECCCCCHHHHCCCCCCCCCEEEEEECCCCCCCCCCH
EATEKYSVLRSLKAIERSDVVLVVLDGEEGIIEQDKKIAGYAHEAGRAIVIVVNKWDAVK
HHHHHHHHHHHHHHHCCCCEEEEEECCCCCCHHCCCHHHCCHHCCCCEEEEEEECCCCCC
KDDKTMQTFVEDIRSEFQFLSYAPICFLSAKTKQRLHLLLPEVRKVSESHHLRVPTHVLN
CCHHHHHHHHHHHHHHHHHHHCCCEEEEECCCHHHHHHHHHHHHHHCCCCCEECCHHHHH
DMIMDAVAMNPTPTDKGKRLKINYVTQVAVQPPTFVFFVNEPELMHFSYRRFLENRLRAT
HHHHHHHCCCCCCCCCCCEEEEEEEEEEEECCCEEEEEECCCHHHHHHHHHHHHHHHCEE
FEFEGTPIHIIARKKND
EEECCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11058132 [H]