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The map label for this gene is xpt

Identifier: 161349958

GI number: 161349958

Start: 3093162

End: 3093737

Strand: Direct

Name: xpt

Synonym: ACIAD3164

Alternate gene names: 161349958

Gene position: 3093162-3093737 (Clockwise)

Preceding gene: 50086164

Following gene: 50086166

Centisome position: 85.95

GC content: 39.58

Gene sequence:

>576_bases
GTGTACGCACTAGAACAGAAAATCTTAAATGAAGGTATCGTTCTATCTGATCAGGTATTGAAAGTTGATGCTTTCTTAAA
CCATCAAATTGACCCAGTACTGATGCAGCAGATCGGCAAAGAGTTTGCTGCTCGTTTTAAAGATACTGGGATCACCAAAA
TTGTAACGATTGAAGCGTCTGGTATTGCACCTGCTGTAATGGCGGGCCTTGAGCTTGGTGTACCTGTGATTTTTGCACGC
AAATATCAGTCTTTGACCTTAAAAGATGATCTTTATCGTTCTAAAGTTTTTTCATTTACCAAACAAGTTGAAAGTACCAT
TGCGATTTCAAATAAGCATATCAATGCAGAAGATAAAGTTTTGGTGATTGATGACTTTCTTGCAAATGGTCAAGCCGCGC
TGGGTCTAATTGACTTGATTCATCAAGCGAATGCAGACATTGTAGGGGTTGGAATTGTGATTGAAAAATCATTTCAGCCT
GGCCGTGATCTTTTACTTGAAAAAGGCTATCGCGTAGAGTCATTGGCGCGCGTTGCATCTTTAACCAATGGGCAAGTGAC
ATTCGTAATTGAATAA

Upstream 100 bases:

>100_bases
CTAAATGATAAATATTTTGTCAATTTTGGCTTGCATTTTTTTATATGCTTTTTAAAATACGCTTTTGCTTGAAAAAGCAT
CTGCCCTAGAGGATTCTCCT

Downstream 100 bases:

>100_bases
GCTCAAACTGTTCAATTATATTTTTAAAAGCGCTACGGCGCTTTTTATTTTGTCTGATCATTATATTTCTGCATTTACAA
GCCCACTAAACTTTTATCAT

Product: xanthine phosphoribosyltransferase

Products: NA

Alternate protein names: XPRTase

Number of amino acids: Translated: 191; Mature: 191

Protein sequence:

>191_residues
MYALEQKILNEGIVLSDQVLKVDAFLNHQIDPVLMQQIGKEFAARFKDTGITKIVTIEASGIAPAVMAGLELGVPVIFAR
KYQSLTLKDDLYRSKVFSFTKQVESTIAISNKHINAEDKVLVIDDFLANGQAALGLIDLIHQANADIVGVGIVIEKSFQP
GRDLLLEKGYRVESLARVASLTNGQVTFVIE

Sequences:

>Translated_191_residues
MYALEQKILNEGIVLSDQVLKVDAFLNHQIDPVLMQQIGKEFAARFKDTGITKIVTIEASGIAPAVMAGLELGVPVIFAR
KYQSLTLKDDLYRSKVFSFTKQVESTIAISNKHINAEDKVLVIDDFLANGQAALGLIDLIHQANADIVGVGIVIEKSFQP
GRDLLLEKGYRVESLARVASLTNGQVTFVIE
>Mature_191_residues
MYALEQKILNEGIVLSDQVLKVDAFLNHQIDPVLMQQIGKEFAARFKDTGITKIVTIEASGIAPAVMAGLELGVPVIFAR
KYQSLTLKDDLYRSKVFSFTKQVESTIAISNKHINAEDKVLVIDDFLANGQAALGLIDLIHQANADIVGVGIVIEKSFQP
GRDLLLEKGYRVESLARVASLTNGQVTFVIE

Specific function: Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis

COG id: COG0503

COG function: function code F; Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. XPT subfamily

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): XPT_ACIAD (Q6F7W2)

Other databases:

- EMBL:   CR543861
- RefSeq:   YP_047675.2
- HSSP:   P42085
- ProteinModelPortal:   Q6F7W2
- SMR:   Q6F7W2
- STRING:   Q6F7W2
- GeneID:   2878630
- GenomeReviews:   CR543861_GR
- KEGG:   aci:ACIAD3164
- NMPDR:   fig|62977.3.peg.2868
- eggNOG:   COG0503
- HOGENOM:   HBG288993
- OMA:   ATVYSFT
- ProtClustDB:   PRK09219
- BioCyc:   ASP62977:ACIAD3164-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_01184
- InterPro:   IPR000836
- InterPro:   IPR010079
- TIGRFAMs:   TIGR01744

Pfam domain/function: PF00156 Pribosyltran

EC number: =2.4.2.22

Molecular weight: Translated: 20913; Mature: 20913

Theoretical pI: Translated: 5.28; Mature: 5.28

Prosite motif: PS00103 PUR_PYR_PR_TRANSFER

Important sites: BINDING 20-20 BINDING 27-27 BINDING 156-156

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MYALEQKILNEGIVLSDQVLKVDAFLNHQIDPVLMQQIGKEFAARFKDTGITKIVTIEAS
CCHHHHHHHHCCCEECCHHEEHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GIAPAVMAGLELGVPVIFARKYQSLTLKDDLYRSKVFSFTKQVESTIAISNKHINAEDKV
CCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCE
LVIDDFLANGQAALGLIDLIHQANADIVGVGIVIEKSFQPGRDLLLEKGYRVESLARVAS
EEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHCCCCHHHHHHHHH
LTNGQVTFVIE
CCCCEEEEEEC
>Mature Secondary Structure
MYALEQKILNEGIVLSDQVLKVDAFLNHQIDPVLMQQIGKEFAARFKDTGITKIVTIEAS
CCHHHHHHHHCCCEECCHHEEHHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEEEEECC
GIAPAVMAGLELGVPVIFARKYQSLTLKDDLYRSKVFSFTKQVESTIAISNKHINAEDKV
CCCHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHEECCCCCCCCCCE
LVIDDFLANGQAALGLIDLIHQANADIVGVGIVIEKSFQPGRDLLLEKGYRVESLARVAS
EEEECCCCCCCHHHHHHHHHHHCCCCEEEEEEEEECCCCCCHHHHHHCCCCHHHHHHHHH
LTNGQVTFVIE
CCCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA