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The map label for this gene is helX [H]

Identifier: 16127904

GI number: 16127904

Start: 3928325

End: 3928837

Strand: Direct

Name: helX [H]

Synonym: CC_3674

Alternate gene names: 16127904

Gene position: 3928325-3928837 (Clockwise)

Preceding gene: 16127903

Following gene: 16127906

Centisome position: 97.79

GC content: 68.81

Gene sequence:

>513_bases
GTGAAGCGCTGGCTGGCCTTTTCGCCGCTGATCGTCCTTGTCGCCCTGGCGGTGCTGTTCGCCGGCTATGCGCTACAGCG
CGATCCCCGCGTGCAGCCCCAGGCCCTGGTCGGCAAGCCCATGCCCGCCCTGATGCTGCCCGATCTGGACACCGGTCGCC
CGGCGCCGCTGCGCCAGACCGGCGAGGGTCCGATCCTGGTCAATTTCTTCGCCTCCTGGTGCGCGCCGTGCGAGGTGGAG
CACCCGCAACTGATGGCGCTGAAGGCCCAGGGCGTGACAGTGGTCGGGATCGCCTACAAGGACGCCCCGGCCAACACCCA
GGCCTTCCTGACCCGTCTTGGCGATCCCTTCGCCGCCAAGCGTGTGGACCGCGATGGCCGCGCAGGCTTGGAGTTCGGCG
TCACCGGCGTTCCGGAGACCTATCTCGTCGGCTCTGATGGCGTGATCATCGCCAAGCACACCGGCCCGCTGACGCCCGAC
GCGGCGGAGGACCTGCTGAAGCAGGCGAAATAG

Upstream 100 bases:

>100_bases
CGGTCGCCTTCGCCTGGCTTATCGGCGACAGCCTGGCCATGGCCCGTCGCTGGCGTCGCGAGGTCGACCGCCTGCAGGCC
GAACTGGACGAGAACCGTCC

Downstream 100 bases:

>100_bases
CCGCTACTTGACGCAGGTCTTGGGCGAGGCGGCCTCGCGCCGGAGTCCCGGCATCATCGCACGCGCTTCGGCGGCGGGGA
TCAACCGCAGGGCTTCGCGG

Product: thiol:disulfide interchange protein CycY

Products: NA

Alternate protein names: Cytochrome c biogenesis protein helX [H]

Number of amino acids: Translated: 170; Mature: 170

Protein sequence:

>170_residues
MKRWLAFSPLIVLVALAVLFAGYALQRDPRVQPQALVGKPMPALMLPDLDTGRPAPLRQTGEGPILVNFFASWCAPCEVE
HPQLMALKAQGVTVVGIAYKDAPANTQAFLTRLGDPFAAKRVDRDGRAGLEFGVTGVPETYLVGSDGVIIAKHTGPLTPD
AAEDLLKQAK

Sequences:

>Translated_170_residues
MKRWLAFSPLIVLVALAVLFAGYALQRDPRVQPQALVGKPMPALMLPDLDTGRPAPLRQTGEGPILVNFFASWCAPCEVE
HPQLMALKAQGVTVVGIAYKDAPANTQAFLTRLGDPFAAKRVDRDGRAGLEFGVTGVPETYLVGSDGVIIAKHTGPLTPD
AAEDLLKQAK
>Mature_170_residues
MKRWLAFSPLIVLVALAVLFAGYALQRDPRVQPQALVGKPMPALMLPDLDTGRPAPLRQTGEGPILVNFFASWCAPCEVE
HPQLMALKAQGVTVVGIAYKDAPANTQAFLTRLGDPFAAKRVDRDGRAGLEFGVTGVPETYLVGSDGVIIAKHTGPLTPD
AAEDLLKQAK

Specific function: Required for disulfide bond formation in some periplasmic proteins. Also act as a disulfide oxidoreductase in cytochromes c biogenesis. The cysteines of apocytochromes c must be in the reduced state for covalent linkage between the two moieties to occur [

COG id: COG0526

COG function: function code OC; Thiol-disulfide isomerase and thioredoxins

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 thioredoxin domain [H]

Homologues:

Organism=Escherichia coli, GI1788523, Length=175, Percent_Identity=39.4285714285714, Blast_Score=121, Evalue=3e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004799
- InterPro:   IPR013740
- InterPro:   IPR005746
- InterPro:   IPR017936
- InterPro:   IPR012336
- InterPro:   IPR017937
- InterPro:   IPR012335 [H]

Pfam domain/function: PF08534 Redoxin [H]

EC number: NA

Molecular weight: Translated: 18170; Mature: 18170

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS00194 THIOREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRWLAFSPLIVLVALAVLFAGYALQRDPRVQPQALVGKPMPALMLPDLDTGRPAPLRQT
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEECCCCCCCCCCCCCCC
GEGPILVNFFASWCAPCEVEHPQLMALKAQGVTVVGIAYKDAPANTQAFLTRLGDPFAAK
CCCCEEEEEHHHHCCCCCCCCCEEEEEEECCEEEEEEEECCCCCCHHHHHHHHCCCHHHH
RVDRDGRAGLEFGVTGVPETYLVGSDGVIIAKHTGPLTPDAAEDLLKQAK
HCCCCCCCCCEECCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHCC
>Mature Secondary Structure
MKRWLAFSPLIVLVALAVLFAGYALQRDPRVQPQALVGKPMPALMLPDLDTGRPAPLRQT
CCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHCCCCCEEECCCCCCCCCCCCCCC
GEGPILVNFFASWCAPCEVEHPQLMALKAQGVTVVGIAYKDAPANTQAFLTRLGDPFAAK
CCCCEEEEEHHHHCCCCCCCCCEEEEEEECCEEEEEEEECCCCCCHHHHHHHHCCCHHHH
RVDRDGRAGLEFGVTGVPETYLVGSDGVIIAKHTGPLTPDAAEDLLKQAK
HCCCCCCCCCEECCCCCCCEEEECCCCEEEEECCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8384715 [H]