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The map label for this gene is ycgM [H]

Identifier: 16127797

GI number: 16127797

Start: 3817968

End: 3818648

Strand: Direct

Name: ycgM [H]

Synonym: CC_3567

Alternate gene names: 16127797

Gene position: 3817968-3818648 (Clockwise)

Preceding gene: 16127793

Following gene: 16127798

Centisome position: 95.05

GC content: 70.04

Gene sequence:

>681_bases
ATGACGACCTACGCTTTTCCCCCGCACGCCATCCCGACGGTCCCGGTGGAGGGATCGGGCGCCCTGTTCCCGGTGCGTCG
CATCCTGTGTGTCGGCCGCAACTACGCCGCCCACCGCCGCGAGATGGGGGGCGATGATCGCGACCCGCCGTTTTTCTTCG
CCAAGCCCGCCGACGCGATCGCGCAGCTGGCCGACGCGATCGCCTATCCGCCGGCGACCAGCGACCTGCATCACGAGATC
GAGCTGGTCGTGGCCCTAAAGGCGGGCGGCGCGGATCTGTCGATCGAACAGGCCCTGGCCTGCGTGTTCGGCTATGCGGT
CGGCGTCGACCTGACGCGCCGCGACCTGCAAGCTGCGGCCAAGGCCAAGGGCCAGCCCTGGGAAGCCGGCAAGGCCTTCG
ATCAGAGCGCCCCGATCAGCGCCATCCGGGTGATGGACGCTCCGGCGGCCGAAGCGGCGGTCACCCTGTCGGTCAACGGC
CAGGAGCGCCAGCGCGGACAGGTCGGCGACATGATCTGGAACATCGGCGAGGTGATCGCCAAGGCCAGCCAGCTGTGGAC
CCTGGCCGCCGGCGACCTGATCTTCACCGGCACGCCTGAGGGCGTCGCCGCCATCGTCCGCGGCGACAAGGTCGTCGGCG
AGATCGAGGGCGTCGGCCGCCTGGACTTCACCCTCGTCTAG

Upstream 100 bases:

>100_bases
TCAACCATCTCGTTGCGAAACGGCGGCCAATTTGAGTCCGGATTTCACGGTTTCGCGACCGGGGTTTTGACACGCGACGT
TTGGGTCTACAGGAGGCGCC

Downstream 100 bases:

>100_bases
CCGCGCAGCGCCGGTCCGCGTCAAAGAGAAAAGGCTGACATGAAGCTCGTCCTGCACAGCGCCAAGCGCGCCAGCGCGCC
CTACCGAGTGCGCATCGGCC

Product: fumarylacetoacetate hydrolase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTTYAFPPHAIPTVPVEGSGALFPVRRILCVGRNYAAHRREMGGDDRDPPFFFAKPADAIAQLADAIAYPPATSDLHHEI
ELVVALKAGGADLSIEQALACVFGYAVGVDLTRRDLQAAAKAKGQPWEAGKAFDQSAPISAIRVMDAPAAEAAVTLSVNG
QERQRGQVGDMIWNIGEVIAKASQLWTLAAGDLIFTGTPEGVAAIVRGDKVVGEIEGVGRLDFTLV

Sequences:

>Translated_226_residues
MTTYAFPPHAIPTVPVEGSGALFPVRRILCVGRNYAAHRREMGGDDRDPPFFFAKPADAIAQLADAIAYPPATSDLHHEI
ELVVALKAGGADLSIEQALACVFGYAVGVDLTRRDLQAAAKAKGQPWEAGKAFDQSAPISAIRVMDAPAAEAAVTLSVNG
QERQRGQVGDMIWNIGEVIAKASQLWTLAAGDLIFTGTPEGVAAIVRGDKVVGEIEGVGRLDFTLV
>Mature_225_residues
TTYAFPPHAIPTVPVEGSGALFPVRRILCVGRNYAAHRREMGGDDRDPPFFFAKPADAIAQLADAIAYPPATSDLHHEIE
LVVALKAGGADLSIEQALACVFGYAVGVDLTRRDLQAAAKAKGQPWEAGKAFDQSAPISAIRVMDAPAAEAAVTLSVNGQ
ERQRGQVGDMIWNIGEVIAKASQLWTLAAGDLIFTGTPEGVAAIVRGDKVVGEIEGVGRLDFTLV

Specific function: Unknown

COG id: COG0179

COG function: function code Q; 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway)

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the FAH family [H]

Homologues:

Organism=Homo sapiens, GI13654274, Length=204, Percent_Identity=37.7450980392157, Blast_Score=139, Evalue=3e-33,
Organism=Homo sapiens, GI215422413, Length=201, Percent_Identity=37.8109452736318, Blast_Score=137, Evalue=8e-33,
Organism=Homo sapiens, GI66348062, Length=204, Percent_Identity=38.7254901960784, Blast_Score=137, Evalue=9e-33,
Organism=Homo sapiens, GI156231349, Length=222, Percent_Identity=31.981981981982, Blast_Score=109, Evalue=2e-24,
Organism=Homo sapiens, GI40786394, Length=222, Percent_Identity=30.6306306306306, Blast_Score=103, Evalue=1e-22,
Organism=Escherichia coli, GI1787428, Length=207, Percent_Identity=41.5458937198068, Blast_Score=160, Evalue=8e-41,
Organism=Caenorhabditis elegans, GI17557057, Length=187, Percent_Identity=35.8288770053476, Blast_Score=130, Evalue=6e-31,
Organism=Saccharomyces cerevisiae, GI6324161, Length=224, Percent_Identity=33.4821428571429, Blast_Score=122, Evalue=5e-29,
Organism=Drosophila melanogaster, GI28572127, Length=205, Percent_Identity=32.6829268292683, Blast_Score=103, Evalue=8e-23,
Organism=Drosophila melanogaster, GI28571789, Length=178, Percent_Identity=33.1460674157303, Blast_Score=101, Evalue=3e-22,
Organism=Drosophila melanogaster, GI24663695, Length=205, Percent_Identity=27.3170731707317, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002529
- InterPro:   IPR011234 [H]

Pfam domain/function: PF01557 FAA_hydrolase [H]

EC number: NA

Molecular weight: Translated: 23846; Mature: 23715

Theoretical pI: Translated: 4.89; Mature: 4.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTYAFPPHAIPTVPVEGSGALFPVRRILCVGRNYAAHRREMGGDDRDPPFFFAKPADAI
CCCCCCCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEECCHHHH
AQLADAIAYPPATSDLHHEIELVVALKAGGADLSIEQALACVFGYAVGVDLTRRDLQAAA
HHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
KAKGQPWEAGKAFDQSAPISAIRVMDAPAAEAAVTLSVNGQERQRGQVGDMIWNIGEVIA
HCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCHHHCCHHHHHHHHHHHHHH
KASQLWTLAAGDLIFTGTPEGVAAIVRGDKVVGEIEGVGRLDFTLV
HHHHHEEEECCCEEEECCCCHHEEEEECCEEEEECCCCCCEEEEEC
>Mature Secondary Structure 
TTYAFPPHAIPTVPVEGSGALFPVRRILCVGRNYAAHRREMGGDDRDPPFFFAKPADAI
CCCCCCCCCCCCCEECCCCCHHHHHHHHHHCCCHHHHHHHCCCCCCCCCEEEECCHHHH
AQLADAIAYPPATSDLHHEIELVVALKAGGADLSIEQALACVFGYAVGVDLTRRDLQAAA
HHHHHHHCCCCCCCCCCCEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHH
KAKGQPWEAGKAFDQSAPISAIRVMDAPAAEAAVTLSVNGQERQRGQVGDMIWNIGEVIA
HCCCCCCCCCCCCCCCCCCEEEEEECCCCCCEEEEEEECCCHHHCCHHHHHHHHHHHHHH
KASQLWTLAAGDLIFTGTPEGVAAIVRGDKVVGEIEGVGRLDFTLV
HHHHHEEEECCCEEEECCCCHHEEEEECCEEEEECCCCCCEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503; 10806384 [H]