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The map label for this gene is rppH

Identifier: 16127670

GI number: 16127670

Start: 3684018

End: 3684536

Strand: Direct

Name: rppH

Synonym: CC_3440

Alternate gene names: 16127670

Gene position: 3684018-3684536 (Clockwise)

Preceding gene: 16127669

Following gene: 16127671

Centisome position: 91.71

GC content: 66.86

Gene sequence:

>519_bases
ATGACTGAGCTGGACCATCCTCAACATCGCCCCAATGTCGGCGTCGTGCTGTTTCACCCGGACGGCCGCGTCTGGCTGGG
CCGACGCCATCGCCAGGCTCCGCCCTACAACTGGCAGTTCCCGCAAGGCGGCGTGGATGAGGGCGAGGACCTCGAGGTCG
CCGCCCGTCGCGAGCTCGCCGAGGAAACCGGCGTCACGTCCGTGGAGTTGCTCGGGCGCACCGAGGGATGGATCACTTAC
GACTTCCCCCCCGAGGTCATGGCCAATCCCAAGCACGCGCGCGGCTGGCGGGGTCAGAAGCAGGTCTGGTTCGCCTACCG
CTTCGTCGGCGAGGAGTCGGAAATCGATCTGGAAGCGGACGAACACATCGAGTTCGACGCTTGGCGATGGGGCAGGCTCG
ACGAAACGCCCGAACTGATCGTACCCTTCAAGCGCGGGGTCTACGAAGCGGTAGTCGCCGCGTTCCAGGGGTTCGCGCGC
GGGGACTCACCGGTCCGCCGCCGCGAGGGGGAGAACTGA

Upstream 100 bases:

>100_bases
CAGGTGCGCGCCTGGGCCGCCGGCCTGCAGGCGCGCGGGATCCAGCTGGCCCCCGCATCGGCCCTGGCGCATCGCTGAGC
GCCTTGAGATAAGCTCAGGC

Downstream 100 bases:

>100_bases
ATGGCGGAAACGGTTCTGTTGATCCATGGCTATGGCTGTGCGGGGGACGTCTGGGGCCCCGTCGCCGAGCGCCTCAAGGC
CGAGGGCTATCGCGTCGAGG

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase

Number of amino acids: Translated: 172; Mature: 171

Protein sequence:

>172_residues
MTELDHPQHRPNVGVVLFHPDGRVWLGRRHRQAPPYNWQFPQGGVDEGEDLEVAARRELAEETGVTSVELLGRTEGWITY
DFPPEVMANPKHARGWRGQKQVWFAYRFVGEESEIDLEADEHIEFDAWRWGRLDETPELIVPFKRGVYEAVVAAFQGFAR
GDSPVRRREGEN

Sequences:

>Translated_172_residues
MTELDHPQHRPNVGVVLFHPDGRVWLGRRHRQAPPYNWQFPQGGVDEGEDLEVAARRELAEETGVTSVELLGRTEGWITY
DFPPEVMANPKHARGWRGQKQVWFAYRFVGEESEIDLEADEHIEFDAWRWGRLDETPELIVPFKRGVYEAVVAAFQGFAR
GDSPVRRREGEN
>Mature_171_residues
TELDHPQHRPNVGVVLFHPDGRVWLGRRHRQAPPYNWQFPQGGVDEGEDLEVAARRELAEETGVTSVELLGRTEGWITYD
FPPEVMANPKHARGWRGQKQVWFAYRFVGEESEIDLEADEHIEFDAWRWGRLDETPELIVPFKRGVYEAVVAAFQGFARG
DSPVRRREGEN

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789194, Length=157, Percent_Identity=37.5796178343949, Blast_Score=101, Evalue=3e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPPH_CAUCN (B8H5H3)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002518926.1
- ProteinModelPortal:   B8H5H3
- SMR:   B8H5H3
- GeneID:   7332551
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_03553
- OMA:   GQKQIWY
- ProtClustDB:   PRK00714
- HAMAP:   MF_00298
- InterPro:   IPR020476
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927
- Gene3D:   G3DSA:3.90.79.10
- PRINTS:   PR00502

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 19893; Mature: 19762

Theoretical pI: Translated: 4.86; Mature: 4.86

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.2 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTELDHPQHRPNVGVVLFHPDGRVWLGRRHRQAPPYNWQFPQGGVDEGEDLEVAARRELA
CCCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
EETGVTSVELLGRTEGWITYDFPPEVMANPKHARGWRGQKQVWFAYRFVGEESEIDLEAD
HHHCCCEEEEEECCCCEEEECCCHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCC
EHIEFDAWRWGRLDETPELIVPFKRGVYEAVVAAFQGFARGDSPVRRREGEN
CCEEECCEECCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCHHHCCCCC
>Mature Secondary Structure 
TELDHPQHRPNVGVVLFHPDGRVWLGRRHRQAPPYNWQFPQGGVDEGEDLEVAARRELA
CCCCCCCCCCCEEEEEECCCCCEEECCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHH
EETGVTSVELLGRTEGWITYDFPPEVMANPKHARGWRGQKQVWFAYRFVGEESEIDLEAD
HHHCCCEEEEEECCCCEEEECCCHHHHCCCCCCCCCCCCCEEEEEEEEECCCCCCCCCCC
EHIEFDAWRWGRLDETPELIVPFKRGVYEAVVAAFQGFARGDSPVRRREGEN
CCEEECCEECCCCCCCCCEEECCHHHHHHHHHHHHHHHCCCCCCHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA