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The map label for this gene is ubiA [H]

Identifier: 16127651

GI number: 16127651

Start: 3666918

End: 3667904

Strand: Direct

Name: ubiA [H]

Synonym: CC_3421

Alternate gene names: 16127651

Gene position: 3666918-3667904 (Clockwise)

Preceding gene: 16127649

Following gene: 16127652

Centisome position: 91.29

GC content: 69.5

Gene sequence:

>987_bases
ATGCGACGAGCGCGCCGTTCGCAGGTTAAGCCTCGCCGCATGACCGCCGCCCAAAGCCCTCCTGGCGTCCTGCCGGACGC
CGCCGCCACCAACTGGGTCGACCGCCATGCGCCGCAGCGCCTGCGGCCCTGGCTGAAGCTGGGCCGGTTCGACCGGCCGG
TGGGGATCTGGCTCTTGATGCTGCCCGGCTGGCAGGGCATCGCCCTGGCCGCCGCCGAGCAGGGCCGCTGGCCCAATCCG
CTGCTGCTGCTGGCCGTGTTCGTCGGCGCGGCCCTGATGCGGGCGGCCGGCTGCGCGTTCAACGACATCGTCGACCGCGA
CTTCGACGCCCAGGTGGCCCGCACGGCGATGCGGCCGATCCCTGCGGGACTGATCAGCGTCAAGCAGGCCTGGCTGTTCG
TGGTCGGCTGCTGCGGGGTCAGTTTCCTGATCCTGATTTGCCTCGGCTGGACCGCGATCCTGCTGGGCGTGCTGTCGCTC
GCCCTCGTCGCCGCCTATCCGTTCATGAAGCGGATCACCTGGTGGCCGCAGGCGTGGCTGGGCCTGACCTTCAACTGGGG
CGCTCTTTTGGGCTACGCCGCCGCGACGGGGCATCTGTCGTGGTCGGCCGCCCTGCTCTACGCCTCGGGCATTTTCTGGA
CCCTGGGCTACGACACGATCTACGCGATCCAGGACATCGAGGACGACGCCCTGGCGGGGATCAAGTCCTCGACCCGGCGC
CTGGGCCAGCATGTCCAGATCGGCGTCGCCGGCTTCTATCTCGTCAGCTTCATCCTGCTGGTGATCGCCGGCTGGATGGG
CGACATCGGCCCGCTGTTCCTGCCGCTGGCGGCCCTGTTCGCCCTGCACCTGTCGCGTCAGGCCGCCGCTGTGCGGATCG
AAGACGGTCCCGGCGCGCTGAAGCTCTTCAAGTCAAACGCGCTGGCGGGCCTTCTGGTGTTCGCAGGCCTGGTGGCCGGG
CTCTGGAAGCCGGGCGTCAGCTTCTAA

Upstream 100 bases:

>100_bases
AGGGTCATGGCGAGAACTCCTCGGGGTTACGCCAAGACCTTCGCGCCGAGGGACTAATAAATCCAATTGATCGTTTTTCG
CGGAGACATCGATCTTCCCT

Downstream 100 bases:

>100_bases
CCTCAAACCCCTTGTCATCCCGGCCAAGCGCGAAGCGCGCAGAGCCGGGACCCAGGGGCCGCCGCACCGCCGCTCGCCCC
TGGGTCCCGGATAGCCTCTG

Product: 4-hydroxybenzoate octaprenyltransferase

Products: NA

Alternate protein names: 4-HB polyprenyltransferase [H]

Number of amino acids: Translated: 328; Mature: 328

Protein sequence:

>328_residues
MRRARRSQVKPRRMTAAQSPPGVLPDAAATNWVDRHAPQRLRPWLKLGRFDRPVGIWLLMLPGWQGIALAAAEQGRWPNP
LLLLAVFVGAALMRAAGCAFNDIVDRDFDAQVARTAMRPIPAGLISVKQAWLFVVGCCGVSFLILICLGWTAILLGVLSL
ALVAAYPFMKRITWWPQAWLGLTFNWGALLGYAAATGHLSWSAALLYASGIFWTLGYDTIYAIQDIEDDALAGIKSSTRR
LGQHVQIGVAGFYLVSFILLVIAGWMGDIGPLFLPLAALFALHLSRQAAAVRIEDGPGALKLFKSNALAGLLVFAGLVAG
LWKPGVSF

Sequences:

>Translated_328_residues
MRRARRSQVKPRRMTAAQSPPGVLPDAAATNWVDRHAPQRLRPWLKLGRFDRPVGIWLLMLPGWQGIALAAAEQGRWPNP
LLLLAVFVGAALMRAAGCAFNDIVDRDFDAQVARTAMRPIPAGLISVKQAWLFVVGCCGVSFLILICLGWTAILLGVLSL
ALVAAYPFMKRITWWPQAWLGLTFNWGALLGYAAATGHLSWSAALLYASGIFWTLGYDTIYAIQDIEDDALAGIKSSTRR
LGQHVQIGVAGFYLVSFILLVIAGWMGDIGPLFLPLAALFALHLSRQAAAVRIEDGPGALKLFKSNALAGLLVFAGLVAG
LWKPGVSF
>Mature_328_residues
MRRARRSQVKPRRMTAAQSPPGVLPDAAATNWVDRHAPQRLRPWLKLGRFDRPVGIWLLMLPGWQGIALAAAEQGRWPNP
LLLLAVFVGAALMRAAGCAFNDIVDRDFDAQVARTAMRPIPAGLISVKQAWLFVVGCCGVSFLILICLGWTAILLGVLSL
ALVAAYPFMKRITWWPQAWLGLTFNWGALLGYAAATGHLSWSAALLYASGIFWTLGYDTIYAIQDIEDDALAGIKSSTRR
LGQHVQIGVAGFYLVSFILLVIAGWMGDIGPLFLPLAALFALHLSRQAAAVRIEDGPGALKLFKSNALAGLLVFAGLVAG
LWKPGVSF

Specific function: Synthesis of 3-octaprenyl-4-hydroxybenzoate [H]

COG id: COG0382

COG function: function code H; 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ubiA prenyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI260656052, Length=310, Percent_Identity=44.8387096774194, Blast_Score=218, Evalue=6e-57,
Organism=Escherichia coli, GI1790473, Length=291, Percent_Identity=36.426116838488, Blast_Score=136, Evalue=2e-33,
Organism=Caenorhabditis elegans, GI17553718, Length=308, Percent_Identity=41.2337662337662, Blast_Score=201, Evalue=3e-52,
Organism=Caenorhabditis elegans, GI32565247, Length=309, Percent_Identity=37.5404530744337, Blast_Score=177, Evalue=5e-45,
Organism=Caenorhabditis elegans, GI17553720, Length=366, Percent_Identity=33.3333333333333, Blast_Score=160, Evalue=9e-40,
Organism=Caenorhabditis elegans, GI32565245, Length=167, Percent_Identity=40.1197604790419, Blast_Score=111, Evalue=5e-25,
Organism=Caenorhabditis elegans, GI32565243, Length=163, Percent_Identity=39.8773006134969, Blast_Score=110, Evalue=8e-25,
Organism=Saccharomyces cerevisiae, GI6324370, Length=279, Percent_Identity=37.2759856630824, Blast_Score=150, Evalue=2e-37,
Organism=Drosophila melanogaster, GI21355567, Length=301, Percent_Identity=41.8604651162791, Blast_Score=214, Evalue=7e-56,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006370
- InterPro:   IPR000537 [H]

Pfam domain/function: PF01040 UbiA [H]

EC number: 2.5.1.-

Molecular weight: Translated: 35555; Mature: 35555

Theoretical pI: Translated: 10.62; Mature: 10.62

Prosite motif: PS00943 UBIA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRRARRSQVKPRRMTAAQSPPGVLPDAAATNWVDRHAPQRLRPWLKLGRFDRPVGIWLLM
CCCCHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEE
LPGWQGIALAAAEQGRWPNPLLLLAVFVGAALMRAAGCAFNDIVDRDFDAQVARTAMRPI
ECCCCCEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCC
PAGLISVKQAWLFVVGCCGVSFLILICLGWTAILLGVLSLALVAAYPFMKRITWWPQAWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GLTFNWGALLGYAAATGHLSWSAALLYASGIFWTLGYDTIYAIQDIEDDALAGIKSSTRR
CCEECHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCHHEEEECCCCHHHHHHHHHHHHH
LGQHVQIGVAGFYLVSFILLVIAGWMGDIGPLFLPLAALFALHLSRQAAAVRIEDGPGAL
HCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHH
KLFKSNALAGLLVFAGLVAGLWKPGVSF
HHHHHHHHHHHHHHHHHHHHHCCCCCCC
>Mature Secondary Structure
MRRARRSQVKPRRMTAAQSPPGVLPDAAATNWVDRHAPQRLRPWLKLGRFDRPVGIWLLM
CCCCHHHCCCCHHHHCCCCCCCCCCCHHHHHHHHHCCCHHHHHHHHHCCCCCCCEEEEEE
LPGWQGIALAAAEQGRWPNPLLLLAVFVGAALMRAAGCAFNDIVDRDFDAQVARTAMRPI
ECCCCCEEEEEHHCCCCCCHHHHHHHHHHHHHHHHHCCHHHHHHCCCCHHHHHHHHHHCC
PAGLISVKQAWLFVVGCCGVSFLILICLGWTAILLGVLSLALVAAYPFMKRITWWPQAWL
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHH
GLTFNWGALLGYAAATGHLSWSAALLYASGIFWTLGYDTIYAIQDIEDDALAGIKSSTRR
CCEECHHHHHHHHHHHCCCHHHHHHHHHHHHHEEECCHHEEEECCCCHHHHHHHHHHHHH
LGQHVQIGVAGFYLVSFILLVIAGWMGDIGPLFLPLAALFALHLSRQAAAVRIEDGPGAL
HCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCEEEEEECCCCHH
KLFKSNALAGLLVFAGLVAGLWKPGVSF
HHHHHHHHHHHHHHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA