Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 16127641

GI number: 16127641

Start: 3652709

End: 3654181

Strand: Direct

Name: tldD [H]

Synonym: CC_3411

Alternate gene names: 16127641

Gene position: 3652709-3654181 (Clockwise)

Preceding gene: 16127640

Following gene: 16127646

Centisome position: 90.93

GC content: 69.79

Gene sequence:

>1473_bases
GTGACGAGCGCGTTCGGAAGTCTTACCTGTAGGACCATGAACGCTCCGATCCCCGCCTCTTCCCTGTCGATCCTGGACGC
CGCCGGCGTCGATCCCGACCGCGCCCGCGCGATCCTGGGCGAAGCCCTGGCCGGCGCCGACGACGGCGAACTGTTCCTCG
AACGCTCCGAGAGCGAGGCCTTCGTCTTCGACGATGGACGCCTCAAGAGCGCCTCCTACGATTCGGGCGAGGGCTTTGGC
CTGCGCGTGGTGGCCGGCGAGACGGCCGGCTACGCCCACGCCGCCGAGATTTCCGAGGCCGCCATCCGCCGCGCCTCTGA
TTCGGCGAGCCTGGCCAAGCGCGGCCACGCCGGCGTCAGCGCCGAAGGGCCGCGCGCCACCAACGAGAAACTCTATGGCG
AGGACAATCCGGTCAGCGCGCCGGACTTTTCCGACAAGGTCGCCCTGCTGCAGGAGATCGACGCCTTCGCCCGTGCCCGC
GACCCGCGCGTCGTGCAGGTGATGGCCTCAATGGCCGGCGAGCGCCGCGTCGTCGAGATCCTCCGCGCCGACGGCCGGCT
GATCCGGGACGTCCGCCCGCTGGTGCGCGTCAATGTCCAGGTCACCGTCGAGAAGGACGGCCGCCGCGAGAGCGGCTCGT
CCGGCGCCGGCGGCCGCGCCGGCTTCGCCGCCTGGATCAGCCCCGACAAGTGGCAGGATCAGGTCGACGAGGCCCTGCGC
ATGGCGCTCGTGAATCTGGACGCCGTCGCCTGCCCCGCCGGCGAGATGGACGTGGTGCTGGGTCCGGGCTGGAACGGCGT
GCTGCTGCATGAGGCCGTCGGCCACGGCCTGGAAGGCGACTTCAACCGCAAGGGCATCAGCGCCTTTTCGGGCCGTATCG
GCGAGCGCGTGGCCGCCCCCGGCGTCACCGTCTTCGACGACGGATCGATCCCCGGTCGCCGCGGCTCTCTGACGGTCGAT
GACGAGGGCACCCCCACCGAGCGCACCATCCTGATCGAGGACGGCATTCTCGTCGGCTACATGCACGATCGGATGAGCGC
CCGCCTGATGGGCATGAAGGCCACCGGCAACGGCCGCCGTCAGTCCTACGCCCACATGCCCATGCCGCGCATGACCAACA
CCGGCATGCTGGCCGGCGAGCACGATCCGCAGGAGATGATCGCCTCGCTGAAGCGCGGCCTCTACTGCGCCAATTTCGGC
GGCGGCCAGGTCGACATCACCAACGGCAAGTTCGTCTTCCAGTGCACCGAGGCTTACCTCGTCGAAGACGGCAAGATCAC
CGCCCCCGTGAAGGGCGCCACCCTGATCGGCGATGGCCCCAGCGCGCTGACCCGCGTGACGATGATCGGCAACGACTTCG
ACTTCGACCCCGGTATCGGCGTCTGCGGCAAGTCGGGCCAAGGCGTGCCGGTGGGCGTGGGCCAGCCGTCGCTGAAGATC
ACCGGCCTGACCGTGGGCGGGACGGCGGTCTAA

Upstream 100 bases:

>100_bases
CGCGGCGGAAAGTCGTCCTCATCCTGGGCTTGTCGAAGGAGGAGGACGACCCCTCGGAGCTGAACCGAGGCTCTCAGGGC
CTTGCGACAAAAGGGGCGGG

Downstream 100 bases:

>100_bases
GGGGACGTCCGAAAGCGCCCCCACCGTCACGCCGCGTATCCGCAGCGCGCCACCTCCCCCGTTTCACGGGTGAGGAGAGC
GATCACTCAGAGCTTCCTGC

Product: tldD protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 490; Mature: 489

Protein sequence:

>490_residues
MTSAFGSLTCRTMNAPIPASSLSILDAAGVDPDRARAILGEALAGADDGELFLERSESEAFVFDDGRLKSASYDSGEGFG
LRVVAGETAGYAHAAEISEAAIRRASDSASLAKRGHAGVSAEGPRATNEKLYGEDNPVSAPDFSDKVALLQEIDAFARAR
DPRVVQVMASMAGERRVVEILRADGRLIRDVRPLVRVNVQVTVEKDGRRESGSSGAGGRAGFAAWISPDKWQDQVDEALR
MALVNLDAVACPAGEMDVVLGPGWNGVLLHEAVGHGLEGDFNRKGISAFSGRIGERVAAPGVTVFDDGSIPGRRGSLTVD
DEGTPTERTILIEDGILVGYMHDRMSARLMGMKATGNGRRQSYAHMPMPRMTNTGMLAGEHDPQEMIASLKRGLYCANFG
GGQVDITNGKFVFQCTEAYLVEDGKITAPVKGATLIGDGPSALTRVTMIGNDFDFDPGIGVCGKSGQGVPVGVGQPSLKI
TGLTVGGTAV

Sequences:

>Translated_490_residues
MTSAFGSLTCRTMNAPIPASSLSILDAAGVDPDRARAILGEALAGADDGELFLERSESEAFVFDDGRLKSASYDSGEGFG
LRVVAGETAGYAHAAEISEAAIRRASDSASLAKRGHAGVSAEGPRATNEKLYGEDNPVSAPDFSDKVALLQEIDAFARAR
DPRVVQVMASMAGERRVVEILRADGRLIRDVRPLVRVNVQVTVEKDGRRESGSSGAGGRAGFAAWISPDKWQDQVDEALR
MALVNLDAVACPAGEMDVVLGPGWNGVLLHEAVGHGLEGDFNRKGISAFSGRIGERVAAPGVTVFDDGSIPGRRGSLTVD
DEGTPTERTILIEDGILVGYMHDRMSARLMGMKATGNGRRQSYAHMPMPRMTNTGMLAGEHDPQEMIASLKRGLYCANFG
GGQVDITNGKFVFQCTEAYLVEDGKITAPVKGATLIGDGPSALTRVTMIGNDFDFDPGIGVCGKSGQGVPVGVGQPSLKI
TGLTVGGTAV
>Mature_489_residues
TSAFGSLTCRTMNAPIPASSLSILDAAGVDPDRARAILGEALAGADDGELFLERSESEAFVFDDGRLKSASYDSGEGFGL
RVVAGETAGYAHAAEISEAAIRRASDSASLAKRGHAGVSAEGPRATNEKLYGEDNPVSAPDFSDKVALLQEIDAFARARD
PRVVQVMASMAGERRVVEILRADGRLIRDVRPLVRVNVQVTVEKDGRRESGSSGAGGRAGFAAWISPDKWQDQVDEALRM
ALVNLDAVACPAGEMDVVLGPGWNGVLLHEAVGHGLEGDFNRKGISAFSGRIGERVAAPGVTVFDDGSIPGRRGSLTVDD
EGTPTERTILIEDGILVGYMHDRMSARLMGMKATGNGRRQSYAHMPMPRMTNTGMLAGEHDPQEMIASLKRGLYCANFGG
GQVDITNGKFVFQCTEAYLVEDGKITAPVKGATLIGDGPSALTRVTMIGNDFDFDPGIGVCGKSGQGVPVGVGQPSLKIT
GLTVGGTAV

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=479, Percent_Identity=51.5657620041754, Blast_Score=456, Evalue=1e-129,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51412; Mature: 51280

Theoretical pI: Translated: 4.91; Mature: 4.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAFGSLTCRTMNAPIPASSLSILDAAGVDPDRARAILGEALAGADDGELFLERSESEA
CCCCCCCEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCE
FVFDDGRLKSASYDSGEGFGLRVVAGETAGYAHAAEISEAAIRRASDSASLAKRGHAGVS
EEEECCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCC
AEGPRATNEKLYGEDNPVSAPDFSDKVALLQEIDAFARARDPRVVQVMASMAGERRVVEI
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHH
LRADGRLIRDVRPLVRVNVQVTVEKDGRRESGSSGAGGRAGFAAWISPDKWQDQVDEALR
HHHCCHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHH
MALVNLDAVACPAGEMDVVLGPGWNGVLLHEAVGHGLEGDFNRKGISAFSGRIGERVAAP
HHHHCCCEEECCCCCEEEEECCCCCCEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
GVTVFDDGSIPGRRGSLTVDDEGTPTERTILIEDGILVGYMHDRMSARLMGMKATGNGRR
CEEEEECCCCCCCCCCEEECCCCCCCCEEEEEECCEEEEEHHHCCCEEEEEEEECCCCCC
QSYAHMPMPRMTNTGMLAGEHDPQEMIASLKRGLYCANFGGGQVDITNGKFVFQCTEAYL
CCCCCCCCCCCCCCCEECCCCCHHHHHHHHHCCEEEEECCCCEEEEECCEEEEEEEEEEE
VEDGKITAPVKGATLIGDGPSALTRVTMIGNDFDFDPGIGVCGKSGQGVPVGVGQPSLKI
EECCEEECCCCCCEEECCCHHHHEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCEEE
TGLTVGGTAV
EEEECCCCCC
>Mature Secondary Structure 
TSAFGSLTCRTMNAPIPASSLSILDAAGVDPDRARAILGEALAGADDGELFLERSESEA
CCCCCCEEEEEECCCCCCCCHHHHHHCCCCHHHHHHHHHHHHCCCCCCCEEEEECCCCE
FVFDDGRLKSASYDSGEGFGLRVVAGETAGYAHAAEISEAAIRRASDSASLAKRGHAGVS
EEEECCCCCCCCCCCCCCEEEEEEECCCCCCHHHHHHHHHHHHHCCCHHHHHHCCCCCCC
AEGPRATNEKLYGEDNPVSAPDFSDKVALLQEIDAFARARDPRVVQVMASMAGERRVVEI
CCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCHHHHHH
LRADGRLIRDVRPLVRVNVQVTVEKDGRRESGSSGAGGRAGFAAWISPDKWQDQVDEALR
HHHCCHHHHHCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCEEEECCCCHHHHHHHHHHH
MALVNLDAVACPAGEMDVVLGPGWNGVLLHEAVGHGLEGDFNRKGISAFSGRIGERVAAP
HHHHCCCEEECCCCCEEEEECCCCCCEEEHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCC
GVTVFDDGSIPGRRGSLTVDDEGTPTERTILIEDGILVGYMHDRMSARLMGMKATGNGRR
CEEEEECCCCCCCCCCEEECCCCCCCCEEEEEECCEEEEEHHHCCCEEEEEEEECCCCCC
QSYAHMPMPRMTNTGMLAGEHDPQEMIASLKRGLYCANFGGGQVDITNGKFVFQCTEAYL
CCCCCCCCCCCCCCCEECCCCCHHHHHHHHHCCEEEEECCCCEEEEECCEEEEEEEEEEE
VEDGKITAPVKGATLIGDGPSALTRVTMIGNDFDFDPGIGVCGKSGQGVPVGVGQPSLKI
EECCEEECCCCCCEEECCCHHHHEEEEEECCCCCCCCCCCCCCCCCCCCEEECCCCCEEE
TGLTVGGTAV
EEEECCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]