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The map label for this gene is mcpA [H]

Identifier: 16127588

GI number: 16127588

Start: 3607152

End: 3608945

Strand: Direct

Name: mcpA [H]

Synonym: CC_3358

Alternate gene names: 16127588

Gene position: 3607152-3608945 (Clockwise)

Preceding gene: 16127586

Following gene: 16127590

Centisome position: 89.8

GC content: 69.29

Gene sequence:

>1794_bases
ATGCTGCGCCTCAACGCCTTCCTGAAACTGCTGACCGTCGCGTTGATGGTCGGCACAATCCTTGCCATCGCCGCAGCGAC
GTTCGGCCTTTTGCATCTGCGGGTCGGCGGACCGATCGCCAACCGTCAAGCCGCCGCCTTCGATCTCGTCGCCGACATCC
TGCCGCCGCCGGCCTATCTGGTCGAGAGCATGCTGGTGGTCGAGCAGGGCAGCCAGGACCCCAGCGCCGCCGAAGCCACC
CTGGTCAAACTGGCCGCGCTGCGCGCCGACTATGAGGCCCGCGTAGCTTACTGGCGAAAATCCGACATTCCCGAGGACGC
CAAGGTTGCGCTCGATCGCCTGGACGTCAGTGGTCGCGCCTTCTGGCGTGAGGTGGACCAGTCCTATGCTCCGGCCCTGC
GGTCGGGCGACGTGATCGCTGTGAACATGGCGGCGGCCAAGCTGGATGGCCACTATCGCCGTCACCGCGTGGGCGTTGAC
GAACTGACGATCAAGGCGCGCGCCATGGTGGCCGCCGCCGCCAGGGAATCGCAGGACGCCTCCCTCACCGTGTTCGCCGG
CCTGGGCGTGGTGGCGGTCGCGATGCTCGGGATGATCCTTCTGGGGGTCGGGGCGCTTCGCAAACGCATCATTCAGCCCC
TCGCGGGAATGACCGCCTATATGGGCCGGCTGGCCGAAGGGGACTATTCCCAGGAGCCGCCCATGCGCGAGCGCAAGGAC
GAGGTCGGCGAGATGGCCGCCGCCGTCTCGGTGTTCCGCGCCGCCGCGATCGAACGTCGCCAGGCCGTCCAGCTGGAGAA
GGACCGCGAGGCGGCGGCGCGCGAAGAGGCTTTTGTGGCGGCCGAGGCCGAAGCCCGGGGCCGGCGCTCGTTCGTGGTGG
ACGCCCTCGACGAAGGTCTGCGCCGCCTAGCTCAGGGCGACCTTTCGCAGCGGATCGACGCGGCGTTCCCCGAGGAGTTC
GAACGCCTGCGTCGCAATTTCAACGACTCGATCGTCACCCTGCGGGAAACCATCCACCAGGTCGTCTCCAGCGCCAGCGC
CGTCGGCGGCGGGGCGCGGCAGATCACGGTGGCGGCCGACGACCTCGCGCGGCGCACCGAGCAGCAGGCCGCCGGACTGG
AACAGACCGCCGCGGCGCTCGACGAGGTGACAGCGACGATCAAGACCACCGCCATCAACGCCCGGACCGCCTACAACGAG
GTGGCGGTCAGTCGCGACCTGATCGGCGCGTCCAGCGCCGTGGCCAGCGAGGCCGGGGTGGCCATGGAGCGGATCGACAC
CTCGTCGCGCAAGATCGGCCAGATCATTACCGTGGTCGACGAAATCGCCTTCCAGACCAACCTGCTGGCTCTGAACGCCG
GGGTCGAGGCCGCCCGTGCGGGTGAGGCCGGTCGCGGCTTCGCCGTCGTGGCCATGGAGGTGCGGGCCCTGGCCCAGCGC
TCGGCCGACGCGGCCAAGGAGATCAAGACCCTGGTCGAGGAAGCCGGCCGCAGCGTCGAAAACGGCGTCGAGCTGGTCGG
CCGGGTCGGGAACGAGCTCACCGGCGTCGTCGCCCAGTTCGGTAAGATCCAGACGCTCGTCGAGGGCATCGCCCAGGCCG
CCCACGATCAGGCCACGGGCCTGGGCGAGGTCAACAGCGCCGTCGGCCAAATGGATCAGGTCACCCAGCAGAACGCCGCC
ATGGTCGAGGAGACCACCGCCGCCAGCCACAGCCTGACCAACGAGGCCCGGCAACTGGCGCAGCTGATGGATCGGTTCAA
GACCGAGGGCGGCGCGGCCACCCTGGCGGCGTAG

Upstream 100 bases:

>100_bases
CAATCTGTCGCGGGTATGGTTACGGCCGCGTTTACCATCGGCCGAGCATCGTTGCAGCGCAGTTCAAGCTTGATCATTCA
ACCCCAAGCCCCGGGTTCAG

Downstream 100 bases:

>100_bases
AGCCCTCTAGCTTTGGATGGGAGCATCCAAAGCGTTGGAAAGAGATCTAAATATCTGATTTTAAAGCCTTACATCCGCTC
TGGCGCTTCGATGCCCAGCA

Product: methyl-accepting chemotaxis protein McpL

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 597; Mature: 597

Protein sequence:

>597_residues
MLRLNAFLKLLTVALMVGTILAIAAATFGLLHLRVGGPIANRQAAAFDLVADILPPPAYLVESMLVVEQGSQDPSAAEAT
LVKLAALRADYEARVAYWRKSDIPEDAKVALDRLDVSGRAFWREVDQSYAPALRSGDVIAVNMAAAKLDGHYRRHRVGVD
ELTIKARAMVAAAARESQDASLTVFAGLGVVAVAMLGMILLGVGALRKRIIQPLAGMTAYMGRLAEGDYSQEPPMRERKD
EVGEMAAAVSVFRAAAIERRQAVQLEKDREAAAREEAFVAAEAEARGRRSFVVDALDEGLRRLAQGDLSQRIDAAFPEEF
ERLRRNFNDSIVTLRETIHQVVSSASAVGGGARQITVAADDLARRTEQQAAGLEQTAAALDEVTATIKTTAINARTAYNE
VAVSRDLIGASSAVASEAGVAMERIDTSSRKIGQIITVVDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAMEVRALAQR
SADAAKEIKTLVEEAGRSVENGVELVGRVGNELTGVVAQFGKIQTLVEGIAQAAHDQATGLGEVNSAVGQMDQVTQQNAA
MVEETTAASHSLTNEARQLAQLMDRFKTEGGAATLAA

Sequences:

>Translated_597_residues
MLRLNAFLKLLTVALMVGTILAIAAATFGLLHLRVGGPIANRQAAAFDLVADILPPPAYLVESMLVVEQGSQDPSAAEAT
LVKLAALRADYEARVAYWRKSDIPEDAKVALDRLDVSGRAFWREVDQSYAPALRSGDVIAVNMAAAKLDGHYRRHRVGVD
ELTIKARAMVAAAARESQDASLTVFAGLGVVAVAMLGMILLGVGALRKRIIQPLAGMTAYMGRLAEGDYSQEPPMRERKD
EVGEMAAAVSVFRAAAIERRQAVQLEKDREAAAREEAFVAAEAEARGRRSFVVDALDEGLRRLAQGDLSQRIDAAFPEEF
ERLRRNFNDSIVTLRETIHQVVSSASAVGGGARQITVAADDLARRTEQQAAGLEQTAAALDEVTATIKTTAINARTAYNE
VAVSRDLIGASSAVASEAGVAMERIDTSSRKIGQIITVVDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAMEVRALAQR
SADAAKEIKTLVEEAGRSVENGVELVGRVGNELTGVVAQFGKIQTLVEGIAQAAHDQATGLGEVNSAVGQMDQVTQQNAA
MVEETTAASHSLTNEARQLAQLMDRFKTEGGAATLAA
>Mature_597_residues
MLRLNAFLKLLTVALMVGTILAIAAATFGLLHLRVGGPIANRQAAAFDLVADILPPPAYLVESMLVVEQGSQDPSAAEAT
LVKLAALRADYEARVAYWRKSDIPEDAKVALDRLDVSGRAFWREVDQSYAPALRSGDVIAVNMAAAKLDGHYRRHRVGVD
ELTIKARAMVAAAARESQDASLTVFAGLGVVAVAMLGMILLGVGALRKRIIQPLAGMTAYMGRLAEGDYSQEPPMRERKD
EVGEMAAAVSVFRAAAIERRQAVQLEKDREAAAREEAFVAAEAEARGRRSFVVDALDEGLRRLAQGDLSQRIDAAFPEEF
ERLRRNFNDSIVTLRETIHQVVSSASAVGGGARQITVAADDLARRTEQQAAGLEQTAAALDEVTATIKTTAINARTAYNE
VAVSRDLIGASSAVASEAGVAMERIDTSSRKIGQIITVVDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAMEVRALAQR
SADAAKEIKTLVEEAGRSVENGVELVGRVGNELTGVVAQFGKIQTLVEGIAQAAHDQATGLGEVNSAVGQMDQVTQQNAA
MVEETTAASHSLTNEARQLAQLMDRFKTEGGAATLAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1787690, Length=290, Percent_Identity=42.4137931034483, Blast_Score=195, Evalue=7e-51,
Organism=Escherichia coli, GI1788194, Length=263, Percent_Identity=46.0076045627376, Blast_Score=192, Evalue=7e-50,
Organism=Escherichia coli, GI2367378, Length=266, Percent_Identity=43.609022556391, Blast_Score=186, Evalue=3e-48,
Organism=Escherichia coli, GI1788195, Length=286, Percent_Identity=42.3076923076923, Blast_Score=184, Evalue=1e-47,
Organism=Escherichia coli, GI1789453, Length=253, Percent_Identity=35.9683794466403, Blast_Score=147, Evalue=2e-36,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 63364; Mature: 63364

Theoretical pI: Translated: 5.02; Mature: 5.02

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRLNAFLKLLTVALMVGTILAIAAATFGLLHLRVGGPIANRQAAAFDLVADILPPPAYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHCCCHHHH
VESMLVVEQGSQDPSAAEATLVKLAALRADYEARVAYWRKSDIPEDAKVALDRLDVSGRA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCHHH
FWREVDQSYAPALRSGDVIAVNMAAAKLDGHYRRHRVGVDELTIKARAMVAAAARESQDA
HHHHHHHHHCCHHCCCCEEEEEHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
SLTVFAGLGVVAVAMLGMILLGVGALRKRIIQPLAGMTAYMGRLAEGDYSQEPPMRERKD
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
EVGEMAAAVSVFRAAAIERRQAVQLEKDREAAAREEAFVAAEAEARGRRSFVVDALDEGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHCCCHHHHHHHHHHHH
RRLAQGDLSQRIDAAFPEEFERLRRNFNDSIVTLRETIHQVVSSASAVGGGARQITVAAD
HHHHHCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHH
DLARRTEQQAAGLEQTAAALDEVTATIKTTAINARTAYNEVAVSRDLIGASSAVASEAGV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHCCHHHHHHHHHH
AMERIDTSSRKIGQIITVVDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAMEVRALAQR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHH
SADAAKEIKTLVEEAGRSVENGVELVGRVGNELTGVVAQFGKIQTLVEGIAQAAHDQATG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LGEVNSAVGQMDQVTQQNAAMVEETTAASHSLTNEARQLAQLMDRFKTEGGAATLAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC
>Mature Secondary Structure
MLRLNAFLKLLTVALMVGTILAIAAATFGLLHLRVGGPIANRQAAAFDLVADILPPPAYL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHCCCHHHH
VESMLVVEQGSQDPSAAEATLVKLAALRADYEARVAYWRKSDIPEDAKVALDRLDVSGRA
HHHHHHHHCCCCCCCHHHHHHHHHHHHHCCHHHHHHHHHCCCCCCHHHHHHHHHCCCHHH
FWREVDQSYAPALRSGDVIAVNMAAAKLDGHYRRHRVGVDELTIKARAMVAAAARESQDA
HHHHHHHHHCCHHCCCCEEEEEHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHCCCCC
SLTVFAGLGVVAVAMLGMILLGVGALRKRIIQPLAGMTAYMGRLAEGDYSQEPPMRERKD
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHH
EVGEMAAAVSVFRAAAIERRQAVQLEKDREAAAREEAFVAAEAEARGRRSFVVDALDEGL
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECHHHCCCHHHHHHHHHHHH
RRLAQGDLSQRIDAAFPEEFERLRRNFNDSIVTLRETIHQVVSSASAVGGGARQITVAAD
HHHHHCCHHHHHHHCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEHH
DLARRTEQQAAGLEQTAAALDEVTATIKTTAINARTAYNEVAVSRDLIGASSAVASEAGV
HHHHHHHHHHCCHHHHHHHHHHHHHHHHHHEECHHHHHHHHHHHHHHHCCHHHHHHHHHH
AMERIDTSSRKIGQIITVVDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAMEVRALAQR
HHHHHCCHHHHHHHHHHHHHHHHHHHHHEEEECCCHHHHCCCCCCCHHHHHHHHHHHHHH
SADAAKEIKTLVEEAGRSVENGVELVGRVGNELTGVVAQFGKIQTLVEGIAQAAHDQATG
HHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
LGEVNSAVGQMDQVTQQNAAMVEETTAASHSLTNEARQLAQLMDRFKTEGGAATLAA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]