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The map label for this gene is ywaD [H]

Identifier: 16127567

GI number: 16127567

Start: 3582717

End: 3585134

Strand: Direct

Name: ywaD [H]

Synonym: CC_3337

Alternate gene names: 16127567

Gene position: 3582717-3585134 (Clockwise)

Preceding gene: 16127566

Following gene: 16127574

Centisome position: 89.19

GC content: 72.21

Gene sequence:

>2418_bases
ATGAAGACCATTCGCTTCCTCGGATTCTGGATCTGTCTCGCCTTGGGGCTGGCGCTGGGCGCGCTGAGCCAACAGCCCCC
GCCTCCGGTCGGCGTCACCGCACCCGCCACCGCGTTTTCGGCCGACCGCGCCATGGCTGATGTCGCGGCGATCGCGCAGA
AGCCCCATCCCACCGGCTCGGCCGAGATTGCAAGGGTCCGCGATCACCTGCTGTCGCGCATCAACGCGCTGCGCCTTGAG
GTCTCGGTCCGCCCGGGCGAAGGCTTCTCCCAGCACGGCTCGGACGGTCGGACCTTGAGCGCGGCCGCCGTGCAGAACCT
GATTGGCATCCTGCCGGGCCGTGACCGCAGCTTGCCGGCCATCCTGGTCATGAGCCACTACGACTCGGTGCACAACTCGC
CGGGCGCAGCCGACGACGCCTCGGGAACCGCCGCCGCCCTGGAGATCGCCCGCGCCCTGAAGGCGAGCGGGCCGCATGCC
CGGGACGTGATCTTCCTGTTCACCGACGCCGAGGAGGCGGGCCTCTTGGGGGCTGACGCGTTCTTCGCCCGCGATCCCAG
CCTCGCACGCGTGGGCTTGGTGGTGAACATGGAGGCCCGGGGCGACGCCGGTCGCGCGGCGATGTTCCAGACCGGTCCCG
GCAACGGCGCGCTCATCGGCGTCTTTGGTCGCGAGGCCAAAGGGGCGTCGGGCAACTCGATGGCCTCGACCGTCTACGAG
AAGATGCCCAACGACACCGATTTCACCCATGCGGTGAACAAGGGTCTGCCGGGGCTGAACCTGGCCTTCATCGACAACCA
GCTGGCCTATCACACGCCGCTGTCGCGCCCCGACCATCTGCAGCGGGGCAGCCTGCAGCATATGGGCGATCAGGTCCTGC
CGACCGTGCGGGCTCTCGCGAACGCGTCCGAACTGCCCGCCAGGACCGAGAATGCGATCTATTCCGACGTCCTGGGCCTG
TTCATGATCCGCTACCCCCCGGCGGTGGGCTGGGCGCTCTTGGCGCTGGCCGCGGCCCTGGTCGGCTTCTGCGCCTGGCG
CGCGCTGGCGGGCCGCGGCGCGAGCGGCTGGGAGATCGCACGCGGCGCGGCCGGGCTGCTCCTCACCGCCGCCAGCGCCG
GTCTCGTGCTGCATCTGCTTGGCCGCCTTCTGATGATCGACGGCGTCCAGCGCTACTACGGCCTGCTGACGCGCTTTGAC
TTTCTGCTCTGGGGCGCGGGTCTGCTCGCCGCCGCCGCGGGGCTGGGCGTCGCCACCGCCCAGGCGCGGGGCGCTCGGCG
GATCATTCCCTGCGTCGCCGCTCTCGTCCTGGGCGGCGCCTGCAGCCTGGTCGGCGGGTTTGATCCCATCGGTCTTGGGC
TTGGGCTGGCCGCGAGCGTTCTGGCCGCCCTGGCGCTGGGCTTCCGCACCGAGGTTCTGGGCGCCTGGATCGGCGGCATG
ATCGTGGTGCTGCTGCTGGCGATCGCCGCCCAGGTCCTGGCGCCCGGCGCGACGGTGATGCTGACCTGGCCGCTGCTGGT
CGCCGCCGTCGGCGCGGCGCTGGTGATCGGGATCGGCGGCACGCGGGACAAGCGGGTCGCCCTGGCCCTGACCACCGTCG
TCGGTCTTCTGGCCATCCTGTCGACCGCCCAGCTGGCCGCCTGGGGGGGCTGGACCTTCGCGGGCGTCGGCCTGATGGAG
CCGGCCGTGCTGGCGGTGTTCGCCATGCTGGCCGCCCCGGCCCTGTCGCCGCTCGCGCACGACTTCGCCGCCACGCGCTG
GGCCTGGCGCGCCGCCGGGATCATGGCCCTGGTCGGGGTGGCGCTTACGGCCAACGCCGCCCGCCTCGGCGGCGAGCCCT
CCCGCCCCGCAATCACCCAGGCCCTGCACGTCGCCGACCTGTCCACCGGCAAGGCCTGGCGCGTCGCCGGCCTGACGAGA
CTGGACGCCTGGACCCGCGCGGTCCTGCCCGACGACGGCGGGTCCGAGCCCCGGCAGCAGGCCCTGGCGCCGTTCTGGAA
AAATCCGGTGTGGATGTCGGAGACCCGGGTCGTGCCCGTGGCCAGCCCACAGCTGACCGTCGACCGCGCCGAGGATCGCC
TGCTGATCCGCCTGATCCCCGCGCCCGGCGCCGAGCTGGTCAGCCTGCGCCTGCGGCCGAGCACGCCGCTCAGCCAACCG
CGCCTGAACGGCCGCCCGATCACCCTGGCGACCCAGGCCGGCGAGTGGTCGAGCCTGACCTATCATGCGCCCGATCCGAA
CGGGATCACGCTCAGCTTCTCGACCGCCGGCCCCGGACAGGTCGAGGTCGCCGCGTTGGAGCATCGCGACGGCTGGCCGA
CCCTGGCCAAGGCGCCGCCGCCGAAGCCTGCTGACCTGATGGCCTTTGGTATGTCGGACAAGACCGCCGTGCTGGTGCGC
GGCGGCCTGTCCTGGTGA

Upstream 100 bases:

>100_bases
TTGGCGGGTCGCCCTTTTTCCTTGTCCGGAGGGGTTTCAGATCGGCGCGCATCGCCGCAGCATACCTTTGGGGATTCGCT
TTCCGCCCGGAGGCACGCCG

Downstream 100 bases:

>100_bases
GCCGCTAGACTGCGAAGACCCCCTCGCCCGGCGTCTTGGCGTAGAGCGCCTCGACACGATCCGCGCGGCGCTCCAGCACG
CAGCGCTGGTTGATATAGCC

Product: M20/M25/M40 family peptidase

Products: NA

Alternate protein names: Arginyl aminopeptidase; BSAP; Leucyl aminopeptidase [H]

Number of amino acids: Translated: 805; Mature: 805

Protein sequence:

>805_residues
MKTIRFLGFWICLALGLALGALSQQPPPPVGVTAPATAFSADRAMADVAAIAQKPHPTGSAEIARVRDHLLSRINALRLE
VSVRPGEGFSQHGSDGRTLSAAAVQNLIGILPGRDRSLPAILVMSHYDSVHNSPGAADDASGTAAALEIARALKASGPHA
RDVIFLFTDAEEAGLLGADAFFARDPSLARVGLVVNMEARGDAGRAAMFQTGPGNGALIGVFGREAKGASGNSMASTVYE
KMPNDTDFTHAVNKGLPGLNLAFIDNQLAYHTPLSRPDHLQRGSLQHMGDQVLPTVRALANASELPARTENAIYSDVLGL
FMIRYPPAVGWALLALAAALVGFCAWRALAGRGASGWEIARGAAGLLLTAASAGLVLHLLGRLLMIDGVQRYYGLLTRFD
FLLWGAGLLAAAAGLGVATAQARGARRIIPCVAALVLGGACSLVGGFDPIGLGLGLAASVLAALALGFRTEVLGAWIGGM
IVVLLLAIAAQVLAPGATVMLTWPLLVAAVGAALVIGIGGTRDKRVALALTTVVGLLAILSTAQLAAWGGWTFAGVGLME
PAVLAVFAMLAAPALSPLAHDFAATRWAWRAAGIMALVGVALTANAARLGGEPSRPAITQALHVADLSTGKAWRVAGLTR
LDAWTRAVLPDDGGSEPRQQALAPFWKNPVWMSETRVVPVASPQLTVDRAEDRLLIRLIPAPGAELVSLRLRPSTPLSQP
RLNGRPITLATQAGEWSSLTYHAPDPNGITLSFSTAGPGQVEVAALEHRDGWPTLAKAPPPKPADLMAFGMSDKTAVLVR
GGLSW

Sequences:

>Translated_805_residues
MKTIRFLGFWICLALGLALGALSQQPPPPVGVTAPATAFSADRAMADVAAIAQKPHPTGSAEIARVRDHLLSRINALRLE
VSVRPGEGFSQHGSDGRTLSAAAVQNLIGILPGRDRSLPAILVMSHYDSVHNSPGAADDASGTAAALEIARALKASGPHA
RDVIFLFTDAEEAGLLGADAFFARDPSLARVGLVVNMEARGDAGRAAMFQTGPGNGALIGVFGREAKGASGNSMASTVYE
KMPNDTDFTHAVNKGLPGLNLAFIDNQLAYHTPLSRPDHLQRGSLQHMGDQVLPTVRALANASELPARTENAIYSDVLGL
FMIRYPPAVGWALLALAAALVGFCAWRALAGRGASGWEIARGAAGLLLTAASAGLVLHLLGRLLMIDGVQRYYGLLTRFD
FLLWGAGLLAAAAGLGVATAQARGARRIIPCVAALVLGGACSLVGGFDPIGLGLGLAASVLAALALGFRTEVLGAWIGGM
IVVLLLAIAAQVLAPGATVMLTWPLLVAAVGAALVIGIGGTRDKRVALALTTVVGLLAILSTAQLAAWGGWTFAGVGLME
PAVLAVFAMLAAPALSPLAHDFAATRWAWRAAGIMALVGVALTANAARLGGEPSRPAITQALHVADLSTGKAWRVAGLTR
LDAWTRAVLPDDGGSEPRQQALAPFWKNPVWMSETRVVPVASPQLTVDRAEDRLLIRLIPAPGAELVSLRLRPSTPLSQP
RLNGRPITLATQAGEWSSLTYHAPDPNGITLSFSTAGPGQVEVAALEHRDGWPTLAKAPPPKPADLMAFGMSDKTAVLVR
GGLSW
>Mature_805_residues
MKTIRFLGFWICLALGLALGALSQQPPPPVGVTAPATAFSADRAMADVAAIAQKPHPTGSAEIARVRDHLLSRINALRLE
VSVRPGEGFSQHGSDGRTLSAAAVQNLIGILPGRDRSLPAILVMSHYDSVHNSPGAADDASGTAAALEIARALKASGPHA
RDVIFLFTDAEEAGLLGADAFFARDPSLARVGLVVNMEARGDAGRAAMFQTGPGNGALIGVFGREAKGASGNSMASTVYE
KMPNDTDFTHAVNKGLPGLNLAFIDNQLAYHTPLSRPDHLQRGSLQHMGDQVLPTVRALANASELPARTENAIYSDVLGL
FMIRYPPAVGWALLALAAALVGFCAWRALAGRGASGWEIARGAAGLLLTAASAGLVLHLLGRLLMIDGVQRYYGLLTRFD
FLLWGAGLLAAAAGLGVATAQARGARRIIPCVAALVLGGACSLVGGFDPIGLGLGLAASVLAALALGFRTEVLGAWIGGM
IVVLLLAIAAQVLAPGATVMLTWPLLVAAVGAALVIGIGGTRDKRVALALTTVVGLLAILSTAQLAAWGGWTFAGVGLME
PAVLAVFAMLAAPALSPLAHDFAATRWAWRAAGIMALVGVALTANAARLGGEPSRPAITQALHVADLSTGKAWRVAGLTR
LDAWTRAVLPDDGGSEPRQQALAPFWKNPVWMSETRVVPVASPQLTVDRAEDRLLIRLIPAPGAELVSLRLRPSTPLSQP
RLNGRPITLATQAGEWSSLTYHAPDPNGITLSFSTAGPGQVEVAALEHRDGWPTLAKAPPPKPADLMAFGMSDKTAVLVR
GGLSW

Specific function: Catalyzes the hydrolysis of a range of N-terminal amino acids [H]

COG id: COG2234

COG function: function code R; Predicted aminopeptidases

Gene ontology:

Cell location: Secreted (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M28 family. M28B subfamily [H]

Homologues:

Organism=Homo sapiens, GI55749804, Length=296, Percent_Identity=36.1486486486487, Blast_Score=155, Evalue=2e-37,
Organism=Caenorhabditis elegans, GI193204254, Length=538, Percent_Identity=28.2527881040892, Blast_Score=142, Evalue=7e-34,
Organism=Caenorhabditis elegans, GI17531383, Length=366, Percent_Identity=27.8688524590164, Blast_Score=124, Evalue=1e-28,
Organism=Saccharomyces cerevisiae, GI6319548, Length=319, Percent_Identity=26.3322884012539, Blast_Score=91, Evalue=8e-19,
Organism=Drosophila melanogaster, GI45550464, Length=695, Percent_Identity=26.1870503597122, Blast_Score=160, Evalue=4e-39,
Organism=Drosophila melanogaster, GI45550463, Length=362, Percent_Identity=30.6629834254144, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI24655610, Length=362, Percent_Identity=30.6629834254144, Blast_Score=158, Evalue=1e-38,
Organism=Drosophila melanogaster, GI281363746, Length=625, Percent_Identity=26.56, Blast_Score=150, Evalue=4e-36,
Organism=Drosophila melanogaster, GI28573565, Length=368, Percent_Identity=29.6195652173913, Blast_Score=141, Evalue=2e-33,
Organism=Drosophila melanogaster, GI221330185, Length=409, Percent_Identity=28.1173594132029, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI24655630, Length=346, Percent_Identity=30.635838150289, Blast_Score=135, Evalue=9e-32,
Organism=Drosophila melanogaster, GI221330187, Length=340, Percent_Identity=32.0588235294118, Blast_Score=135, Evalue=1e-31,
Organism=Drosophila melanogaster, GI28573381, Length=372, Percent_Identity=30.9139784946237, Blast_Score=132, Evalue=7e-31,
Organism=Drosophila melanogaster, GI24655613, Length=320, Percent_Identity=29.375, Blast_Score=132, Evalue=1e-30,
Organism=Drosophila melanogaster, GI24652993, Length=384, Percent_Identity=26.8229166666667, Blast_Score=131, Evalue=2e-30,
Organism=Drosophila melanogaster, GI24652989, Length=275, Percent_Identity=32.7272727272727, Blast_Score=130, Evalue=3e-30,
Organism=Drosophila melanogaster, GI28573701, Length=388, Percent_Identity=26.5463917525773, Blast_Score=128, Evalue=2e-29,
Organism=Drosophila melanogaster, GI28573379, Length=299, Percent_Identity=28.7625418060201, Blast_Score=92, Evalue=2e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR007484
- InterPro:   IPR003137 [H]

Pfam domain/function: PF02225 PA; PF04389 Peptidase_M28 [H]

EC number: =3.4.11.6; =3.4.11.10 [H]

Molecular weight: Translated: 83444; Mature: 83444

Theoretical pI: Translated: 9.71; Mature: 9.71

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTIRFLGFWICLALGLALGALSQQPPPPVGVTAPATAFSADRAMADVAAIAQKPHPTGS
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
AEIARVRDHLLSRINALRLEVSVRPGEGFSQHGSDGRTLSAAAVQNLIGILPGRDRSLPA
HHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCE
ILVMSHYDSVHNSPGAADDASGTAAALEIARALKASGPHARDVIFLFTDAEEAGLLGADA
EEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCH
FFARDPSLARVGLVVNMEARGDAGRAAMFQTGPGNGALIGVFGREAKGASGNSMASTVYE
HHCCCCCCEEEEEEEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHH
KMPNDTDFTHAVNKGLPGLNLAFIDNQLAYHTPLSRPDHLQRGSLQHMGDQVLPTVRALA
HCCCCCCHHHHHHCCCCCCEEEEECCCHHCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHH
NASELPARTENAIYSDVLGLFMIRYPPAVGWALLALAAALVGFCAWRALAGRGASGWEIA
CHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RGAAGLLLTAASAGLVLHLLGRLLMIDGVQRYYGLLTRFDFLLWGAGLLAAAAGLGVATA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QARGARRIIPCVAALVLGGACSLVGGFDPIGLGLGLAASVLAALALGFRTEVLGAWIGGM
HHCCCHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVVLLLAIAAQVLAPGATVMLTWPLLVAAVGAALVIGIGGTRDKRVALALTTVVGLLAIL
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHH
STAQLAAWGGWTFAGVGLMEPAVLAVFAMLAAPALSPLAHDFAATRWAWRAAGIMALVGV
HHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALTANAARLGGEPSRPAITQALHVADLSTGKAWRVAGLTRLDAWTRAVLPDDGGSEPRQQ
HHHCCHHHCCCCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHEECCCCCCCCHHHH
ALAPFWKNPVWMSETRVVPVASPQLTVDRAEDRLLIRLIPAPGAELVSLRLRPSTPLSQP
HHHHHHCCCCEECCCEEEECCCCCEEEECCCCEEEEEEECCCCCEEEEEEECCCCCCCCC
RLNGRPITLATQAGEWSSLTYHAPDPNGITLSFSTAGPGQVEVAALEHRDGWPTLAKAPP
CCCCCCEEEEECCCCCCCEEEECCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCC
PKPADLMAFGMSDKTAVLVRGGLSW
CCCCHHEEECCCCCEEEEEECCCCC
>Mature Secondary Structure
MKTIRFLGFWICLALGLALGALSQQPPPPVGVTAPATAFSADRAMADVAAIAQKPHPTGS
CCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
AEIARVRDHLLSRINALRLEVSVRPGEGFSQHGSDGRTLSAAAVQNLIGILPGRDRSLPA
HHHHHHHHHHHHHHHEEEEEEEECCCCCCCCCCCCCCEEHHHHHHHHHHCCCCCCCCCCE
ILVMSHYDSVHNSPGAADDASGTAAALEIARALKASGPHARDVIFLFTDAEEAGLLGADA
EEEEEHHHHHCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCEEEEEEECCCCCCCCCCCH
FFARDPSLARVGLVVNMEARGDAGRAAMFQTGPGNGALIGVFGREAKGASGNSMASTVYE
HHCCCCCCEEEEEEEEEECCCCCCCEEEEECCCCCCEEEEEECCCCCCCCCCHHHHHHHH
KMPNDTDFTHAVNKGLPGLNLAFIDNQLAYHTPLSRPDHLQRGSLQHMGDQVLPTVRALA
HCCCCCCHHHHHHCCCCCCEEEEECCCHHCCCCCCCCCCCCCCCHHHHCHHHHHHHHHHH
NASELPARTENAIYSDVLGLFMIRYPPAVGWALLALAAALVGFCAWRALAGRGASGWEIA
CHHHCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHH
RGAAGLLLTAASAGLVLHLLGRLLMIDGVQRYYGLLTRFDFLLWGAGLLAAAAGLGVATA
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
QARGARRIIPCVAALVLGGACSLVGGFDPIGLGLGLAASVLAALALGFRTEVLGAWIGGM
HHCCCHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IVVLLLAIAAQVLAPGATVMLTWPLLVAAVGAALVIGIGGTRDKRVALALTTVVGLLAIL
HHHHHHHHHHHHHCCCCEEEHHHHHHHHHHHHHEEEECCCCCCCHHHHHHHHHHHHHHHH
STAQLAAWGGWTFAGVGLMEPAVLAVFAMLAAPALSPLAHDFAATRWAWRAAGIMALVGV
HHHHHHHCCCCHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ALTANAARLGGEPSRPAITQALHVADLSTGKAWRVAGLTRLDAWTRAVLPDDGGSEPRQQ
HHHCCHHHCCCCCCCCHHHHHHHHHCCCCCCEEEECCCHHHHHHHHEECCCCCCCCHHHH
ALAPFWKNPVWMSETRVVPVASPQLTVDRAEDRLLIRLIPAPGAELVSLRLRPSTPLSQP
HHHHHHCCCCEECCCEEEECCCCCEEEECCCCEEEEEEECCCCCEEEEEEECCCCCCCCC
RLNGRPITLATQAGEWSSLTYHAPDPNGITLSFSTAGPGQVEVAALEHRDGWPTLAKAPP
CCCCCCEEEEECCCCCCCEEEECCCCCCEEEEEECCCCCCEEEEEEECCCCCCCCCCCCC
PKPADLMAFGMSDKTAVLVRGGLSW
CCCCHHEEECCCCCEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7934828; 9384377; 1806041 [H]