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The map label for this gene is kinB [H]

Identifier: 16127557

GI number: 16127557

Start: 3574018

End: 3576303

Strand: Direct

Name: kinB [H]

Synonym: CC_3327

Alternate gene names: 16127557

Gene position: 3574018-3576303 (Clockwise)

Preceding gene: 16127556

Following gene: 16127565

Centisome position: 88.97

GC content: 69.03

Gene sequence:

>2286_bases
GTGAGGGAGACCGGCTCCCGCCCGTCACGCTCAGGCGAACGGCGGCTGTCGTGGCTCTGGCTGGCGATGGCCGCCAGCCT
GGTGTTCGCCGTCTTCGCGGTACGGCCGCCCAGTCGGATCGATAATGTCCTCTACGACGTTCTGACGCGCGCCAACGCCC
ATCCCGCCGATGACTCCATCCTGATCGTCGACATCGACGATCGCAGCCTGGCCCGGATGGGGGCTTGGCCTTGGGGGCGC
GACACGCACGCCCGGATGGTCGACCAACTGACCCAGGCGGGGGCCAAGACCATCGTCTACGATGTGCTGTTCAGCCAGCC
GTCGCGCGATCCCGCCCAAGACCGTGCGCTGGGCGAAGCGATCGCCCGTTCCGGACGGGTCTACCTCCCGGAGTTCCTGA
TCGACGGCGGCGAGCAAGCGCCTCCTCGCGTCGTCGGATCGATTTCCGAGATCGCCCGGGGCGCGGCCGGGGTTGGCCTG
GCGCACGTGCGCTTTGATGACGACGGCGTGGTGCGCCGCATGGCGCCGTTCGAGGCGAACGGGCCGAGTCTCAAGCCCGA
CCTGATGACCGTCGTCCACCGCGCCACCCGTCCGCCGGGCTCGCCGGATGTGACACGGGGTAATGAGCAGACGCTGCTGA
TCTCCTTTGCGGGCCCCCCGTCGATCTATCGTCATGCCAGTTTCGCGAGCGTGCTCGACGGGGAAGTGCCCCGTGAGTTG
ATCGCGGGACGGACCGTCTTCGTCGGCTTGACCGCGCCGGGCCTTGGCCCCGCCTTTCCGACGCCCGTCACCCCGGACGC
CGCCAGCATGACCGGCGTTCAGCTGCAGGCCAGCGTGCTCGACGCCTTGCGAAGCGGCCGGATGATCACGCCGGCCGGCC
CCTGGAGCCGCGTCGGGTTCAGCCTGACATTGCTCTGGCTACTGATGATCGGGTTCATGGCCCTGCCGCCACGCGCCAAT
CTGCTGCTGACCATCGGCCTCTGCCTGGTGGGTCTGGCCTATTCGGCGGCGCTGTTCTGGCTGGGCCATATCTGGCTCTC
CCCGATCACGACCGTGATCGGCCTGCAACTCGTCGCCCTGATCTGGGGCTGGGGCCGCCTGGGCCAGGTGAACGACCTGA
TCGGACGCGAGCTGGCGCGCGTCCGGGCCGTCGTTCGCGGGCGAGGCGCGAAACCCGCCGCGTTCTCGGGCGACGTCGTG
ACGCGCCAGGCTTCCAGCCTCGGTGACGCGATCACGCGCATGGACGATCTGCGCCGCTTCTCGGCCGACGCCCTGTTCAG
CCTCCCGGACGCCACCTTGGTGGCGAACGAGCAAGGGCGGGTGATCGCCGCGAACGCTGCGGCCCAGGCCCTTTTCAAGC
CGCATCAGGCGACCCTGAACGGCGCATCGCTGGCGGACTTGATCAATCTGCTGGACCCCCTGGGGCGACGCTTCGAACTC
GACTGGCCGCAGGCCACGGACCGCCACGATCCGATCGACCTGCACCTGCCCGACGGCCGGGCCTTTCAGCTGCAGACCGT
CCTTCGTCGAGACGAGCATGGCGGCCCCGCCGGATGGATCGTTCGCCTGGCCGACATCTCGATCCTGACCGCCGCCATGC
GCCAGCGGGAGCAGGCTTTGCAGCTGCTGACCCATGACATGCGCTCGCCACAGACCTCGATCCTGGCCTTGCTGGCCACC
ACGCCCGACCTGCCCAAGGAGACGGCCGACCGCATCGCCGCCTATGCTCGCCGCACGCTCGCCCTCGCCGACGGCTTCGT
GCAGTTGGCTCGCGCCGAGGTCACGCCGGTCTCGCTGGAACCCCTGGATCTGGCCGATGTCGCGGTCGAGGCGATCGATG
AAGTCTGGCCCCAGTCCTTGCAGCGCAAGATCCGCATCGAGCAGGTCGGCGGCGAAGCGCCCTTGATGGTGCTGGGGGAC
CGAAGCGTGCTCGCCCGCACGTTCGTCAACCTGCTGGGCAACGCCCTGAAATACAGCCCCTCTGGATCGACGATCACGGT
CAACCTGGCTGAGCAGCCCTCACCCAGCGGACCGGTCGCCTGCATCGCCATCGCCGACCAGGGACCCGGTTTCTCCCGCG
AAGAGGCGGCGACCGCCTTTCGGCCCTTCCAAAGGTTCGAACGGCCGGGGCATGAGCTGGCCAGCAACGGCGTCGGTCTT
GGACTGGCGTTCGTGCAGGCGGCGGTCGCCCGGCACGGGGGCGAGGTTTCCTGCCGCAGCGAACCCGGCGTGGGCGCGGA
ATTCACCGTGCGCCTGCCACGACACGGCGTCGTGCAAGGCGGTTAA

Upstream 100 bases:

>100_bases
TGGCGCCGGGCGCCTATGCCTGGCGCGTCACCGCGCTGCGCTTCAAGGACGGCGTGATGAGTGAGAAGCAGGGGCCGCTG
CAGCAGCTGCAGATCGGGAA

Downstream 100 bases:

>100_bases
GGCCGGTCTGCGCCCTTCAGGGCGTCCACCAGAAGCTTGGCGACAGCCTCCGGCGCTTGCTCTCCGACTCGAACCGAAGA
CCAGGCGATGGTCTTCCCGT

Product: sensory box histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 761; Mature: 761

Protein sequence:

>761_residues
MRETGSRPSRSGERRLSWLWLAMAASLVFAVFAVRPPSRIDNVLYDVLTRANAHPADDSILIVDIDDRSLARMGAWPWGR
DTHARMVDQLTQAGAKTIVYDVLFSQPSRDPAQDRALGEAIARSGRVYLPEFLIDGGEQAPPRVVGSISEIARGAAGVGL
AHVRFDDDGVVRRMAPFEANGPSLKPDLMTVVHRATRPPGSPDVTRGNEQTLLISFAGPPSIYRHASFASVLDGEVPREL
IAGRTVFVGLTAPGLGPAFPTPVTPDAASMTGVQLQASVLDALRSGRMITPAGPWSRVGFSLTLLWLLMIGFMALPPRAN
LLLTIGLCLVGLAYSAALFWLGHIWLSPITTVIGLQLVALIWGWGRLGQVNDLIGRELARVRAVVRGRGAKPAAFSGDVV
TRQASSLGDAITRMDDLRRFSADALFSLPDATLVANEQGRVIAANAAAQALFKPHQATLNGASLADLINLLDPLGRRFEL
DWPQATDRHDPIDLHLPDGRAFQLQTVLRRDEHGGPAGWIVRLADISILTAAMRQREQALQLLTHDMRSPQTSILALLAT
TPDLPKETADRIAAYARRTLALADGFVQLARAEVTPVSLEPLDLADVAVEAIDEVWPQSLQRKIRIEQVGGEAPLMVLGD
RSVLARTFVNLLGNALKYSPSGSTITVNLAEQPSPSGPVACIAIADQGPGFSREEAATAFRPFQRFERPGHELASNGVGL
GLAFVQAAVARHGGEVSCRSEPGVGAEFTVRLPRHGVVQGG

Sequences:

>Translated_761_residues
MRETGSRPSRSGERRLSWLWLAMAASLVFAVFAVRPPSRIDNVLYDVLTRANAHPADDSILIVDIDDRSLARMGAWPWGR
DTHARMVDQLTQAGAKTIVYDVLFSQPSRDPAQDRALGEAIARSGRVYLPEFLIDGGEQAPPRVVGSISEIARGAAGVGL
AHVRFDDDGVVRRMAPFEANGPSLKPDLMTVVHRATRPPGSPDVTRGNEQTLLISFAGPPSIYRHASFASVLDGEVPREL
IAGRTVFVGLTAPGLGPAFPTPVTPDAASMTGVQLQASVLDALRSGRMITPAGPWSRVGFSLTLLWLLMIGFMALPPRAN
LLLTIGLCLVGLAYSAALFWLGHIWLSPITTVIGLQLVALIWGWGRLGQVNDLIGRELARVRAVVRGRGAKPAAFSGDVV
TRQASSLGDAITRMDDLRRFSADALFSLPDATLVANEQGRVIAANAAAQALFKPHQATLNGASLADLINLLDPLGRRFEL
DWPQATDRHDPIDLHLPDGRAFQLQTVLRRDEHGGPAGWIVRLADISILTAAMRQREQALQLLTHDMRSPQTSILALLAT
TPDLPKETADRIAAYARRTLALADGFVQLARAEVTPVSLEPLDLADVAVEAIDEVWPQSLQRKIRIEQVGGEAPLMVLGD
RSVLARTFVNLLGNALKYSPSGSTITVNLAEQPSPSGPVACIAIADQGPGFSREEAATAFRPFQRFERPGHELASNGVGL
GLAFVQAAVARHGGEVSCRSEPGVGAEFTVRLPRHGVVQGG
>Mature_761_residues
MRETGSRPSRSGERRLSWLWLAMAASLVFAVFAVRPPSRIDNVLYDVLTRANAHPADDSILIVDIDDRSLARMGAWPWGR
DTHARMVDQLTQAGAKTIVYDVLFSQPSRDPAQDRALGEAIARSGRVYLPEFLIDGGEQAPPRVVGSISEIARGAAGVGL
AHVRFDDDGVVRRMAPFEANGPSLKPDLMTVVHRATRPPGSPDVTRGNEQTLLISFAGPPSIYRHASFASVLDGEVPREL
IAGRTVFVGLTAPGLGPAFPTPVTPDAASMTGVQLQASVLDALRSGRMITPAGPWSRVGFSLTLLWLLMIGFMALPPRAN
LLLTIGLCLVGLAYSAALFWLGHIWLSPITTVIGLQLVALIWGWGRLGQVNDLIGRELARVRAVVRGRGAKPAAFSGDVV
TRQASSLGDAITRMDDLRRFSADALFSLPDATLVANEQGRVIAANAAAQALFKPHQATLNGASLADLINLLDPLGRRFEL
DWPQATDRHDPIDLHLPDGRAFQLQTVLRRDEHGGPAGWIVRLADISILTAAMRQREQALQLLTHDMRSPQTSILALLAT
TPDLPKETADRIAAYARRTLALADGFVQLARAEVTPVSLEPLDLADVAVEAIDEVWPQSLQRKIRIEQVGGEAPLMVLGD
RSVLARTFVNLLGNALKYSPSGSTITVNLAEQPSPSGPVACIAIADQGPGFSREEAATAFRPFQRFERPGHELASNGVGL
GLAFVQAAVARHGGEVSCRSEPGVGAEFTVRLPRHGVVQGG

Specific function: Member of the two-component regulatory system AlgB/KinB involved in regulation of alginate biosynthesis genes. KinB functions as a membrane-associated protein kinase that phosphorylates AlgB, probably in response to environmental signals [H]

COG id: COG4252

COG function: function code T; Predicted transmembrane sensor domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1786600, Length=349, Percent_Identity=24.9283667621776, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI145693157, Length=237, Percent_Identity=26.5822784810127, Blast_Score=77, Evalue=3e-15,
Organism=Escherichia coli, GI1786912, Length=229, Percent_Identity=30.1310043668122, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI1788393, Length=254, Percent_Identity=28.3464566929134, Blast_Score=69, Evalue=8e-13,
Organism=Escherichia coli, GI1790346, Length=239, Percent_Identity=26.7782426778243, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787894, Length=229, Percent_Identity=25.3275109170306, Blast_Score=67, Evalue=5e-12,
Organism=Escherichia coli, GI1790436, Length=238, Percent_Identity=23.9495798319328, Blast_Score=64, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR003660
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR013656
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF00672 HAMP; PF02518 HATPase_c; PF00512 HisKA; PF08448 PAS_4 [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 81712; Mature: 81712

Theoretical pI: Translated: 7.48; Mature: 7.48

Prosite motif: PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRETGSRPSRSGERRLSWLWLAMAASLVFAVFAVRPPSRIDNVLYDVLTRANAHPADDSI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCE
LIVDIDDRSLARMGAWPWGRDTHARMVDQLTQAGAKTIVYDVLFSQPSRDPAQDRALGEA
EEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHH
IARSGRVYLPEFLIDGGEQAPPRVVGSISEIARGAAGVGLAHVRFDDDGVVRRMAPFEAN
HHHCCCEEEHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHCCCCCCC
GPSLKPDLMTVVHRATRPPGSPDVTRGNEQTLLISFAGPPSIYRHASFASVLDGEVPREL
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCHHH
IAGRTVFVGLTAPGLGPAFPTPVTPDAASMTGVQLQASVLDALRSGRMITPAGPWSRVGF
HCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCCCCHHHHHH
SLTLLWLLMIGFMALPPRANLLLTIGLCLVGLAYSAALFWLGHIWLSPITTVIGLQLVAL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWGWGRLGQVNDLIGRELARVRAVVRGRGAKPAAFSGDVVTRQASSLGDAITRMDDLRRF
HHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SADALFSLPDATLVANEQGRVIAANAAAQALFKPHQATLNGASLADLINLLDPLGRRFEL
HHHHHHCCCCCEEEECCCCCEEEECHHHHHHHCCCHHCCCCHHHHHHHHHHHHCCCCEEC
DWPQATDRHDPIDLHLPDGRAFQLQTVLRRDEHGGPAGWIVRLADISILTAAMRQREQAL
CCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QLLTHDMRSPQTSILALLATTPDLPKETADRIAAYARRTLALADGFVQLARAEVTPVSLE
HHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PLDLADVAVEAIDEVWPQSLQRKIRIEQVGGEAPLMVLGDRSVLARTFVNLLGNALKYSP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHEECC
SGSTITVNLAEQPSPSGPVACIAIADQGPGFSREEAATAFRPFQRFERPGHELASNGVGL
CCCEEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCH
GLAFVQAAVARHGGEVSCRSEPGVGAEFTVRLPRHGVVQGG
HHHHHHHHHHHCCCCEEECCCCCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure
MRETGSRPSRSGERRLSWLWLAMAASLVFAVFAVRPPSRIDNVLYDVLTRANAHPADDSI
CCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCCCE
LIVDIDDRSLARMGAWPWGRDTHARMVDQLTQAGAKTIVYDVLFSQPSRDPAQDRALGEA
EEEEECCCHHHHHCCCCCCCCHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCHHHHHHHHH
IARSGRVYLPEFLIDGGEQAPPRVVGSISEIARGAAGVGLAHVRFDDDGVVRRMAPFEAN
HHHCCCEEEHHHHHCCCCCCCHHHHHHHHHHHCCCCCCCEEEEEECCCCHHHHCCCCCCC
GPSLKPDLMTVVHRATRPPGSPDVTRGNEQTLLISFAGPPSIYRHASFASVLDGEVPREL
CCCCCHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEECCCCHHHHHHHHHHHHCCCCCHHH
IAGRTVFVGLTAPGLGPAFPTPVTPDAASMTGVQLQASVLDALRSGRMITPAGPWSRVGF
HCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCEECCCCCHHHHHH
SLTLLWLLMIGFMALPPRANLLLTIGLCLVGLAYSAALFWLGHIWLSPITTVIGLQLVAL
HHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
IWGWGRLGQVNDLIGRELARVRAVVRGRGAKPAAFSGDVVTRQASSLGDAITRMDDLRRF
HHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
SADALFSLPDATLVANEQGRVIAANAAAQALFKPHQATLNGASLADLINLLDPLGRRFEL
HHHHHHCCCCCEEEECCCCCEEEECHHHHHHHCCCHHCCCCHHHHHHHHHHHHCCCCEEC
DWPQATDRHDPIDLHLPDGRAFQLQTVLRRDEHGGPAGWIVRLADISILTAAMRQREQAL
CCCCCCCCCCCEEEECCCCCCCHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
QLLTHDMRSPQTSILALLATTPDLPKETADRIAAYARRTLALADGFVQLARAEVTPVSLE
HHHHHHHCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
PLDLADVAVEAIDEVWPQSLQRKIRIEQVGGEAPLMVLGDRSVLARTFVNLLGNALKYSP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCEEEECCHHHHHHHHHHHHHHHHEECC
SGSTITVNLAEQPSPSGPVACIAIADQGPGFSREEAATAFRPFQRFERPGHELASNGVGL
CCCEEEEEECCCCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHHHCCCCHHHHHCCCCH
GLAFVQAAVARHGGEVSCRSEPGVGAEFTVRLPRHGVVQGG
HHHHHHHHHHHCCCCEEECCCCCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9218420 [H]