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The map label for this gene is arpC [H]

Identifier: 16127425

GI number: 16127425

Start: 3446737

End: 3448239

Strand: Direct

Name: arpC [H]

Synonym: CC_3195

Alternate gene names: 16127425

Gene position: 3446737-3448239 (Clockwise)

Preceding gene: 16127423

Following gene: 16127426

Centisome position: 85.8

GC content: 69.46

Gene sequence:

>1503_bases
ATGCGTCTCGCCACGACCGGCGCCCTATTGCGACCAGAGCAGCCTGTAGGCTTGTCGCGCGCCGCTCCCATCATGACGCT
CATGGTTCTCGGCCTGGGGCTGGCGGCCTGCACGACCCCGGCGCGCAAGGCGGAGGTCCAGCTGCCGAGCGCCTATGAGG
CCCCGGCCGGTCCTGCCCTCGCGCCCCAGGCCCTGGATCAATGGTGGACGCAGTTCAACGACCCCGCCCTGAACGCGCTT
GTCACCACGGCGCTGGCTCAGAGCCCCGATGCGCGGCTTGCGGCGGCGCGTCTTGAAGAAGCGCGCGCCATCCGCCAGGG
CCAGATCCGCCAGATCTTCATTCCACAGACGCCGCTCGTCGGTTCGGCCCAACGCACCGACACCGACATCAACGAGCAAA
GCGGCGTCGGCGCCTTCACCCAGGGCGGGGTCAGCAAGACCTACTCCGCCAATTTCGACGTCTCCTGGGAGCTGGACCTG
ATCGGCCGCCGCCTCGCTGCGCTGCGGGTGGTGAAGAACGATATGGCCGCGGCGCGCTTCGCCTATGAGGGCGCGCGTGC
GGCCCTGGCCGCCAATGTCGCCCAGTCCTATTTCGAGGCGCGGGGACTGGCGGTCCAGCTGGATGACGCCCGCGAAAGCG
TGCGGATCGCCAGGTCGCTGGCCGATGTCGCTGCTGAGCGGGGTCGGCGTGGCCTGATCGCCACCTCCGAAGGCGAACGC
GCCGCCGCCGATCTTGCCCAGGCCGAAGCCCAGGCCGCGGCTTTGGAAGCGGAGCTCCGCGCCGCGCGCCGCACGCTTCT
GATCCTGGTCGGCAAGGGCGTCGATCCGCTCGAAACCCTGCCCGTCACGGCGTCGCTGGCCAAGCCGCCGCCGGTTCCCG
CTGCAACGCCCGGCCAACTGCTGGCGCGGCGTCCCGATGTGCGCGAGGCGGCCGCTCGCCTGGCCTCGGCCTCGGGCAAT
CTCAACATCAGCGAACTGGCGCTGTTCCCTACCCTGACGCTGACGCCGGGGGGCGGGATCTCCAAGGCCATCACGCCCAG
CTTCCTGGACGCCGGCGCGCAAACCTCGACGACCAGTTCGGCCTGGACGATCGGAGCCAATCTTTCGATCCCGGTTCTGA
ACATTCCCAAGCTGATGACCGACATTAAGGCCAGCAACGCCAGGGTCGAACAGGCCGCGATCACCTATGAAAAGACGGTC
CAGACCGCGTTCGGCGAAGCTGACAACGCCCTCGTCCAGCTGGCCGCAGACGAGCGGCGCGTGGCGCTGTTGACGGCGGG
CGAACGCCGCGCCGCCGTGGCCTATGAAGCAAGCCGCAAGAGCTTTGCGGCCGGGCTGACCGACCTGACGACGGCCCTGC
AGGCCGAACAGGCCTGGCGCGCCGTTCGCTCGGCCTCTACGGCCGCTCAGACCCAGGCGCTGCAGCGCGCCGTGCAAACC
TACAAGGCTCTTGGCGGCGGTTGGTCGCCCGAGGCCGTCCCGACCAAGGCTTCCGCGCAATGA

Upstream 100 bases:

>100_bases
ACCTCTCGAACGGGGGTTTCCCTCCCGGGGCCGGCCCCCTAAGTGGGAGACCATTGGTCGCCTGGGCGCGCCGCGCGTCA
CAACAACTGGGTTGAATTTC

Downstream 100 bases:

>100_bases
GACCCGCTCCGATGACGACCCGCTATCTGATCGCCACCGCCCTGGTCTGCGCCGGCGTGGGCCTGACCGCCTGTGGCGGC
AAGAAGGACGCGCCCGCCGA

Product: efflux system protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
MRLATTGALLRPEQPVGLSRAAPIMTLMVLGLGLAACTTPARKAEVQLPSAYEAPAGPALAPQALDQWWTQFNDPALNAL
VTTALAQSPDARLAAARLEEARAIRQGQIRQIFIPQTPLVGSAQRTDTDINEQSGVGAFTQGGVSKTYSANFDVSWELDL
IGRRLAALRVVKNDMAAARFAYEGARAALAANVAQSYFEARGLAVQLDDARESVRIARSLADVAAERGRRGLIATSEGER
AAADLAQAEAQAAALEAELRAARRTLLILVGKGVDPLETLPVTASLAKPPPVPAATPGQLLARRPDVREAAARLASASGN
LNISELALFPTLTLTPGGGISKAITPSFLDAGAQTSTTSSAWTIGANLSIPVLNIPKLMTDIKASNARVEQAAITYEKTV
QTAFGEADNALVQLAADERRVALLTAGERRAAVAYEASRKSFAAGLTDLTTALQAEQAWRAVRSASTAAQTQALQRAVQT
YKALGGGWSPEAVPTKASAQ

Sequences:

>Translated_500_residues
MRLATTGALLRPEQPVGLSRAAPIMTLMVLGLGLAACTTPARKAEVQLPSAYEAPAGPALAPQALDQWWTQFNDPALNAL
VTTALAQSPDARLAAARLEEARAIRQGQIRQIFIPQTPLVGSAQRTDTDINEQSGVGAFTQGGVSKTYSANFDVSWELDL
IGRRLAALRVVKNDMAAARFAYEGARAALAANVAQSYFEARGLAVQLDDARESVRIARSLADVAAERGRRGLIATSEGER
AAADLAQAEAQAAALEAELRAARRTLLILVGKGVDPLETLPVTASLAKPPPVPAATPGQLLARRPDVREAAARLASASGN
LNISELALFPTLTLTPGGGISKAITPSFLDAGAQTSTTSSAWTIGANLSIPVLNIPKLMTDIKASNARVEQAAITYEKTV
QTAFGEADNALVQLAADERRVALLTAGERRAAVAYEASRKSFAAGLTDLTTALQAEQAWRAVRSASTAAQTQALQRAVQT
YKALGGGWSPEAVPTKASAQ
>Mature_500_residues
MRLATTGALLRPEQPVGLSRAAPIMTLMVLGLGLAACTTPARKAEVQLPSAYEAPAGPALAPQALDQWWTQFNDPALNAL
VTTALAQSPDARLAAARLEEARAIRQGQIRQIFIPQTPLVGSAQRTDTDINEQSGVGAFTQGGVSKTYSANFDVSWELDL
IGRRLAALRVVKNDMAAARFAYEGARAALAANVAQSYFEARGLAVQLDDARESVRIARSLADVAAERGRRGLIATSEGER
AAADLAQAEAQAAALEAELRAARRTLLILVGKGVDPLETLPVTASLAKPPPVPAATPGQLLARRPDVREAAARLASASGN
LNISELALFPTLTLTPGGGISKAITPSFLDAGAQTSTTSSAWTIGANLSIPVLNIPKLMTDIKASNARVEQAAITYEKTV
QTAFGEADNALVQLAADERRVALLTAGERRAAVAYEASRKSFAAGLTDLTTALQAEQAWRAVRSASTAAQTQALQRAVQT
YKALGGGWSPEAVPTKASAQ

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: COG1538

COG function: function code MU; Outer membrane protein

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=445, Percent_Identity=26.9662921348315, Blast_Score=115, Evalue=8e-27,
Organism=Escherichia coli, GI2367348, Length=456, Percent_Identity=23.2456140350877, Blast_Score=63, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 52324; Mature: 52324

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
1.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLATTGALLRPEQPVGLSRAAPIMTLMVLGLGLAACTTPARKAEVQLPSAYEAPAGPAL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCEEECCCCCCCCCCCCC
APQALDQWWTQFNDPALNALVTTALAQSPDARLAAARLEEARAIRQGQIRQIFIPQTPLV
CHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
GSAQRTDTDINEQSGVGAFTQGGVSKTYSANFDVSWELDLIGRRLAALRVVKNDMAAARF
CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
AYEGARAALAANVAQSYFEARGLAVQLDDARESVRIARSLADVAAERGRRGLIATSEGER
HHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCH
AAADLAQAEAQAAALEAELRAARRTLLILVGKGVDPLETLPVTASLAKPPPVPAATPGQL
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHCCCEEECCCCCCCCCCCCHHH
LARRPDVREAAARLASASGNLNISELALFPTLTLTPGGGISKAITPSFLDAGAQTSTTSS
HHCCCCHHHHHHHHHHCCCCCCHHHEEEEEEEEECCCCCCCHHCCHHHHHCCCCCCCCCC
AWTIGANLSIPVLNIPKLMTDIKASNARVEQAAITYEKTVQTAFGEADNALVQLAADERR
EEEECCCCCCCEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCE
VALLTAGERRAAVAYEASRKSFAAGLTDLTTALQAEQAWRAVRSASTAAQTQALQRAVQT
EEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKALGGGWSPEAVPTKASAQ
HHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MRLATTGALLRPEQPVGLSRAAPIMTLMVLGLGLAACTTPARKAEVQLPSAYEAPAGPAL
CCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCHHCEEECCCCCCCCCCCCC
APQALDQWWTQFNDPALNALVTTALAQSPDARLAAARLEEARAIRQGQIRQIFIPQTPLV
CHHHHHHHHHHCCCHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCEEEECCCCCCC
GSAQRTDTDINEQSGVGAFTQGGVSKTYSANFDVSWELDLIGRRLAALRVVKNDMAAARF
CCCCCCCCCCCCCCCCCCCCCCCCCCEEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHH
AYEGARAALAANVAQSYFEARGLAVQLDDARESVRIARSLADVAAERGRRGLIATSEGER
HHHHHHHHHHHHHHHHHHHHCCCEEEECCHHHHHHHHHHHHHHHHHCCCCCEEEECCCCH
AAADLAQAEAQAAALEAELRAARRTLLILVGKGVDPLETLPVTASLAKPPPVPAATPGQL
HHHHHHHHHHHHHHHHHHHHHHHCEEEEEECCCCCCHHHCCCEEECCCCCCCCCCCCHHH
LARRPDVREAAARLASASGNLNISELALFPTLTLTPGGGISKAITPSFLDAGAQTSTTSS
HHCCCCHHHHHHHHHHCCCCCCHHHEEEEEEEEECCCCCCCHHCCHHHHHCCCCCCCCCC
AWTIGANLSIPVLNIPKLMTDIKASNARVEQAAITYEKTVQTAFGEADNALVQLAADERR
EEEECCCCCCCEECHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCE
VALLTAGERRAAVAYEASRKSFAAGLTDLTTALQAEQAWRAVRSASTAAQTQALQRAVQT
EEEEECCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
YKALGGGWSPEAVPTKASAQ
HHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]