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The map label for this gene is grp [H]

Identifier: 16127407

GI number: 16127407

Start: 3424923

End: 3425594

Strand: Direct

Name: grp [H]

Synonym: CC_3177

Alternate gene names: 16127407

Gene position: 3424923-3425594 (Clockwise)

Preceding gene: 16127402

Following gene: 16127408

Centisome position: 85.26

GC content: 61.61

Gene sequence:

>672_bases
TTGTCGTCGAGAGTGACTTCTGAGTGCCGCATAGCAAAAATCTTCCTCCCGGGTCTTCTCGCCCGCCACGCAATATCTTA
TAGAAGCGCGGAAAATGTTTGCCCAAGGCGTGCCCGAGTCGTGGCCGCTTTGCGCAAAATCAAAGCGCCAACGCCCTCTG
GGGGGAGGAATTTCTTGTCCGAACAACTCGACGCCGTGGATGCCAAGATTCTGGATCTCATCCAACACGACGCCGGACTG
TCCGTCGCGGAGATCGCCGAACGTGTGGGTCTGTCGTCCAGCCCGTGCTGGCGCCGGATCAAGCGCCTGGAAGACGCCGG
CGTCATCCAGCGCCGCGTGACCATCCTTGACCGCGAAAAGCTGGGCCTGGGCTTTGAGGTGTATTGCACCGTGAAGCTGT
CGCTACCGACCAAGGAAAACCTCGACACCTTCGAACAGGCCGTCGGCAAGTGGGCCGAGGTCGTCCAGTGCGCCACCGTG
ACCGGCGCGGCCGACTATGAGATGCGCATCGTCACCCGCGACATGCGCGCCTTTGACGAGTTCCTGCGCGACAAACTGCT
GTCGCTGGGCCTGGTCAGCAATATCGAGAGCCGGATCGTCATCCGGGGCGTCAAGAACTCCACCGCCGTGCCGCTGGGAC
TGGTCAGCCCGTATGTCAGCCCGCTGAGCTAG

Upstream 100 bases:

>100_bases
GTTCAACCCGGCCTTGCGGTCGAGACGCTTGCGATCCAGCAGAACGCGAAGCAGGGCCTGCACCCCAGTGATGAAGGCGC
GACCATCTTCGAGCACATAT

Downstream 100 bases:

>100_bases
CGACTTTCCTTCTCCCCTTGCGGGAGAAGGTGTCGACGCAGTCGACGGATGAGGGGTCGCACCAGCGGCCCCTTTTTTCG
TACGCGGACGCCCCCAGAAA

Product: AsnC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 223; Mature: 222

Protein sequence:

>223_residues
MSSRVTSECRIAKIFLPGLLARHAISYRSAENVCPRRARVVAALRKIKAPTPSGGRNFLSEQLDAVDAKILDLIQHDAGL
SVAEIAERVGLSSSPCWRRIKRLEDAGVIQRRVTILDREKLGLGFEVYCTVKLSLPTKENLDTFEQAVGKWAEVVQCATV
TGAADYEMRIVTRDMRAFDEFLRDKLLSLGLVSNIESRIVIRGVKNSTAVPLGLVSPYVSPLS

Sequences:

>Translated_223_residues
MSSRVTSECRIAKIFLPGLLARHAISYRSAENVCPRRARVVAALRKIKAPTPSGGRNFLSEQLDAVDAKILDLIQHDAGL
SVAEIAERVGLSSSPCWRRIKRLEDAGVIQRRVTILDREKLGLGFEVYCTVKLSLPTKENLDTFEQAVGKWAEVVQCATV
TGAADYEMRIVTRDMRAFDEFLRDKLLSLGLVSNIESRIVIRGVKNSTAVPLGLVSPYVSPLS
>Mature_222_residues
SSRVTSECRIAKIFLPGLLARHAISYRSAENVCPRRARVVAALRKIKAPTPSGGRNFLSEQLDAVDAKILDLIQHDAGLS
VAEIAERVGLSSSPCWRRIKRLEDAGVIQRRVTILDREKLGLGFEVYCTVKLSLPTKENLDTFEQAVGKWAEVVQCATVT
GAADYEMRIVTRDMRAFDEFLRDKLLSLGLVSNIESRIVIRGVKNSTAVPLGLVSPYVSPLS

Specific function: Represses the secondary, H(+)-coupled glutamate uptake system (Gluemp) genes [H]

COG id: COG1522

COG function: function code K; Transcriptional regulators

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH asnC-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI87081742, Length=150, Percent_Identity=36, Blast_Score=108, Evalue=3e-25,
Organism=Escherichia coli, GI1787116, Length=148, Percent_Identity=33.1081081081081, Blast_Score=89, Evalue=2e-19,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011008
- InterPro:   IPR013196
- InterPro:   IPR000485
- InterPro:   IPR019885
- InterPro:   IPR019888
- InterPro:   IPR019887
- InterPro:   IPR011991 [H]

Pfam domain/function: PF01037 AsnC_trans_reg; PF08279 HTH_11 [H]

EC number: NA

Molecular weight: Translated: 24609; Mature: 24478

Theoretical pI: Translated: 9.78; Mature: 9.78

Prosite motif: PS00519 HTH_ASNC_1 ; PS50956 HTH_ASNC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
2.3 %Cys     (Mature Protein)
0.9 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSRVTSECRIAKIFLPGLLARHAISYRSAENVCPRRARVVAALRKIKAPTPSGGRNFLS
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHH
EQLDAVDAKILDLIQHDAGLSVAEIAERVGLSSSPCWRRIKRLEDAGVIQRRVTILDREK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLGFEVYCTVKLSLPTKENLDTFEQAVGKWAEVVQCATVTGAADYEMRIVTRDMRAFDE
HCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHH
FLRDKLLSLGLVSNIESRIVIRGVKNSTAVPLGLVSPYVSPLS
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCCCCC
>Mature Secondary Structure 
SSRVTSECRIAKIFLPGLLARHAISYRSAENVCPRRARVVAALRKIKAPTPSGGRNFLS
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCCCCCCHHHHHH
EQLDAVDAKILDLIQHDAGLSVAEIAERVGLSSSPCWRRIKRLEDAGVIQRRVTILDREK
HHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGLGFEVYCTVKLSLPTKENLDTFEQAVGKWAEVVQCATVTGAADYEMRIVTRDMRAFDE
HCCCEEEEEEEEEECCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCEEHHHHHHHHHHHH
FLRDKLLSLGLVSNIESRIVIRGVKNSTAVPLGLVSPYVSPLS
HHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7665494 [H]