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The map label for this gene is luxQ [H]

Identifier: 16127392

GI number: 16127392

Start: 3409313

End: 3410497

Strand: Direct

Name: luxQ [H]

Synonym: CC_3162

Alternate gene names: 16127392

Gene position: 3409313-3410497 (Clockwise)

Preceding gene: 16127391

Following gene: 16127394

Centisome position: 84.87

GC content: 69.11

Gene sequence:

>1185_bases
GTGGGCGGGCTTGCCTCCCTGCTGGCCTCGCACCGACGCCGCCAGCACGAAGCGCGCGACGCCATGGCCATTGTCGAACG
GATGGCCGTCGACATCGGCGCGCATCTCGACGGCGTTCTGGCCATCACCGAACGGCTTGAGCAACAACGCCTGACGCCAG
ACGCCGCAGCCTTCGTCCGAGCCATCGGCGACACCAGCCGCGACATGGGCGAGACCGTCGGCCGCGCGGTGGACCTCCAT
CGCTCGGTCAACGGCGACCTCCAGATGGACGCCGCGCCCACGCGACTGCGCGATTTCGCTGACCTCGTCGAAGCCCGGTG
GGCCAACCGGGCGAGCGAAGGCGGCTCCACGCTTCTCGTCTCTTATGACGGCGATCCCGAATGCGGCGTCGAGATTGATG
GCGAGCGTCTGCTGCAGGTGATCGACATTCTGGTCGAGAACGCCCTGTCCGCCGGACGGGGCATGATCGAGGTTCGCCTC
TCCGCGCGCGCCGAAGACGATCGGATCACTCTGGACTGCCAACTGCGCGACAACGCCGGCGGACACGCCGAAGATCGACT
GCGCCGCGTCAATGATCCGCTCGGCGGCGTCGGCGGCCAGGATCGCAGCGAGATGGCCCTGGGCGTCGGTCTCGCGCTGG
CCCAAAGTGTCGTTCGCACGATGGGCGGCCGACTGATCGCCGAAGCCAATCGCGGGGCGGGGCTGACCGTCGGGTTCTCG
CTGCCCCTCATCCCGGCGGCCGCCGAAGCGGCGGCCCAAGACGCCCCAGAGCCCGTCGGCGGACGTTCGGCCCACATTCT
CATCGTCGATGACAACGCCACCAACCGCATGGTGGCCGAGGCGCTTTGCGACATGTTCGAGTGCACCTCCGAACAGGCCG
TCGACGGTGTCGAGGCCGTCGAGATGGCCCGGAGCGGCCGCTTTGACCTCATCCTCATGGACATCAAGATGCCGCGCATG
GACGGCGTCGCGGCCACGCGCGCCATCCGCGAGCTGAGCGGCCGTTCGAGCGCCGCCCCGATCGTGGCCCTGACCGCCAA
CGCCGATCCGGCCGACGTCCACACCTACCTCGCGGCGGGTATGCAGGACGTGGTCGAAAAGCCAATCAAGCCCGAGCGTC
TCGCCCTGGTGCTCAACAGCCTGCTGGCCGGCGCAGACGGCGACAGCGCCGAAGCCGCCGCCTAG

Upstream 100 bases:

>100_bases
CACCGATCCCAACACCTTCGTCAACGCCCTCGCCGACAGCCCGACACCCATCTTCCGCACCGCCTATGTCGCGGTCGACG
CCGACGGGCGCTACGCCGGC

Downstream 100 bases:

>100_bases
AGCGTTCGCCGATCAGTGTGAAACGGTGATCGGAGCGAAGAGCGCTCCAAACTTTTGAAATAGAGCCCTTGTCACGCTCA
GAGGATCTCGTCTCAGGCTA

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 394; Mature: 393

Protein sequence:

>394_residues
MGGLASLLASHRRRQHEARDAMAIVERMAVDIGAHLDGVLAITERLEQQRLTPDAAAFVRAIGDTSRDMGETVGRAVDLH
RSVNGDLQMDAAPTRLRDFADLVEARWANRASEGGSTLLVSYDGDPECGVEIDGERLLQVIDILVENALSAGRGMIEVRL
SARAEDDRITLDCQLRDNAGGHAEDRLRRVNDPLGGVGGQDRSEMALGVGLALAQSVVRTMGGRLIAEANRGAGLTVGFS
LPLIPAAAEAAAQDAPEPVGGRSAHILIVDDNATNRMVAEALCDMFECTSEQAVDGVEAVEMARSGRFDLILMDIKMPRM
DGVAATRAIRELSGRSSAAPIVALTANADPADVHTYLAAGMQDVVEKPIKPERLALVLNSLLAGADGDSAEAAA

Sequences:

>Translated_394_residues
MGGLASLLASHRRRQHEARDAMAIVERMAVDIGAHLDGVLAITERLEQQRLTPDAAAFVRAIGDTSRDMGETVGRAVDLH
RSVNGDLQMDAAPTRLRDFADLVEARWANRASEGGSTLLVSYDGDPECGVEIDGERLLQVIDILVENALSAGRGMIEVRL
SARAEDDRITLDCQLRDNAGGHAEDRLRRVNDPLGGVGGQDRSEMALGVGLALAQSVVRTMGGRLIAEANRGAGLTVGFS
LPLIPAAAEAAAQDAPEPVGGRSAHILIVDDNATNRMVAEALCDMFECTSEQAVDGVEAVEMARSGRFDLILMDIKMPRM
DGVAATRAIRELSGRSSAAPIVALTANADPADVHTYLAAGMQDVVEKPIKPERLALVLNSLLAGADGDSAEAAA
>Mature_393_residues
GGLASLLASHRRRQHEARDAMAIVERMAVDIGAHLDGVLAITERLEQQRLTPDAAAFVRAIGDTSRDMGETVGRAVDLHR
SVNGDLQMDAAPTRLRDFADLVEARWANRASEGGSTLLVSYDGDPECGVEIDGERLLQVIDILVENALSAGRGMIEVRLS
ARAEDDRITLDCQLRDNAGGHAEDRLRRVNDPLGGVGGQDRSEMALGVGLALAQSVVRTMGGRLIAEANRGAGLTVGFSL
PLIPAAAEAAAQDAPEPVGGRSAHILIVDDNATNRMVAEALCDMFECTSEQAVDGVEAVEMARSGRFDLILMDIKMPRMD
GVAATRAIRELSGRSSAAPIVALTANADPADVHTYLAAGMQDVVEKPIKPERLALVLNSLLAGADGDSAEAAA

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=404, Percent_Identity=25.4950495049505, Blast_Score=121, Evalue=9e-29,
Organism=Escherichia coli, GI1788713, Length=260, Percent_Identity=27.6923076923077, Blast_Score=98, Evalue=1e-21,
Organism=Escherichia coli, GI1789149, Length=138, Percent_Identity=39.1304347826087, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1787487, Length=114, Percent_Identity=33.3333333333333, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI145693157, Length=106, Percent_Identity=34.9056603773585, Blast_Score=63, Evalue=3e-11,
Organism=Saccharomyces cerevisiae, GI6322000, Length=147, Percent_Identity=32.6530612244898, Blast_Score=84, Evalue=3e-17,
Organism=Saccharomyces cerevisiae, GI6322044, Length=132, Percent_Identity=33.3333333333333, Blast_Score=78, Evalue=3e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 41594; Mature: 41462

Theoretical pI: Translated: 4.49; Mature: 4.49

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MGGLASLLASHRRRQHEARDAMAIVERMAVDIGAHLDGVLAITERLEQQRLTPDAAAFVR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHH
AIGDTSRDMGETVGRAVDLHRSVNGDLQMDAAPTRLRDFADLVEARWANRASEGGSTLLV
HHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
SYDGDPECGVEIDGERLLQVIDILVENALSAGRGMIEVRLSARAEDDRITLDCQLRDNAG
EECCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEECCCCC
GHAEDRLRRVNDPLGGVGGQDRSEMALGVGLALAQSVVRTMGGRLIAEANRGAGLTVGFS
CCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEC
LPLIPAAAEAAAQDAPEPVGGRSAHILIVDDNATNRMVAEALCDMFECTSEQAVDGVEAV
CCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
EMARSGRFDLILMDIKMPRMDGVAATRAIRELSGRSSAAPIVALTANADPADVHTYLAAG
HHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHH
MQDVVEKPIKPERLALVLNSLLAGADGDSAEAAA
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
GGLASLLASHRRRQHEARDAMAIVERMAVDIGAHLDGVLAITERLEQQRLTPDAAAFVR
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCHHHHHHHH
AIGDTSRDMGETVGRAVDLHRSVNGDLQMDAAPTRLRDFADLVEARWANRASEGGSTLLV
HHCCCCHHHHHHHHHHHHHHHCCCCCEEECCCHHHHHHHHHHHHHHHHHCCCCCCCEEEE
SYDGDPECGVEIDGERLLQVIDILVENALSAGRGMIEVRLSARAEDDRITLDCQLRDNAG
EECCCCCCCEEECHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCCCCEEEEEEEECCCCC
GHAEDRLRRVNDPLGGVGGQDRSEMALGVGLALAQSVVRTMGGRLIAEANRGAGLTVGFS
CCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCEEEEECCCCCCEEEEEC
LPLIPAAAEAAAQDAPEPVGGRSAHILIVDDNATNRMVAEALCDMFECTSEQAVDGVEAV
CCCCHHHHHHHHHCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHCCHHHHHHHHHHH
EMARSGRFDLILMDIKMPRMDGVAATRAIRELSGRSSAAPIVALTANADPADVHTYLAAG
HHHHCCCCEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHHHHHHH
MQDVVEKPIKPERLALVLNSLLAGADGDSAEAAA
HHHHHHCCCCHHHHHHHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA