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The map label for this gene is aroC

Identifier: 16127384

GI number: 16127384

Start: 3401177

End: 3402295

Strand: Direct

Name: aroC

Synonym: CC_3154

Alternate gene names: 16127384

Gene position: 3401177-3402295 (Clockwise)

Preceding gene: 16127382

Following gene: 16127385

Centisome position: 84.67

GC content: 69.35

Gene sequence:

>1119_bases
ATGTCGCACAACACCTTTGGTCACCTGTTCCGCGTCACCACCTGGGGCGAGAGCCACGGCCCGGCGCTCGGCTGCGTCGT
CGACGGCTGCCCTCCCGGGATCGCCCTGACGGCGGAGATGATCCAGGTGTTCCTCGACAAGCGCCGCCCGGGCAACGGCA
AGTTCGTCACCCAGCGCCAGGAGCCGGACGCCGTGCGCATCCTGTCGGGCGTGTTCGAGGACGCGCGCTCGAACGGCCAG
CGCACCACGGGCACGCCGATCAGCCTGATGATCGAGAACACCGACCAGCGCAGCAAGGACTATTCGGAGATCGCCCAGGC
CTTCCGGCCCGGCCACGCCGACTACGCCTATTTCGCCAAGTACGGCGTGCGCGACTATCGCGGCGGCGGGCGCAGCTCGG
CCCGCGAAACCGCCGCGCGGGTGGCCGCCGGCGCCGTCGCGCGCCTGATCATTCCGGGCGTGACGGTGCGCGCCGCCCTC
GTGCAGATCGGCCCGCATAAGATCGACCGGTCCAACTGGGACTGGGCCCAGACCGAGCAGAACCCCTACTGGTCTCCCGA
CGCGGCCATTGTGCCGGTCTGGGAGGAGCACCTCGAAAAGATCCGCAAGGCCGGCTCCTCCACCGGCGCCGTCGTCGAGG
TCGAGGCTACCGGTGTTCCAGCCGGCTGGGGCGCGCCGCTCTATGCCAAGCTGGACGCCGAGTTGGCCGCCGCCCTGATG
TCGATCAATGCGGCCAAGGGGGTCGAGATCGGCGACGGCTTCGACAGCGCCGCCCTCACGGGCGAGGATAACGCCGACAC
GATGCGCATGGGCGATGACGGGCAGCCGGTGTTCCAATCCAATCACGCGGGTGGGATTCTGGGCGGCATCTCCTCGGGCC
AACCGATTGTCGCGCGTGTGGCGTTCAAGCCGACCTCGTCGATCCTGATCCCGCGCGAGACGGTCAATGAGGCCGGCGAG
GAGATCGAGCTTCGCACCAAGGGTCGCCATGACCCGTGCGTCGGCATCCGGGGCGTGCCGGTGGTTGAGGCCATGACCGC
GTGCGTGCTGGCCGACGCCTTCCTGCGCCATCGCGGGCAAACCGGCCGGGAGCACTTCCCGCTTGGCGCGAGCGCATAA

Upstream 100 bases:

>100_bases
GGCGGCGGAGATATTACTTTAAATTGTATAGCGGGCTCTCGCAACCGACGCCGGCGCGACCACTTTGCCCCCTCGCGCGC
TTTCCGCTAGAAGCCGCCCC

Downstream 100 bases:

>100_bases
TCAGCGCGACCTTAGGGCAAAACCCCGCCAGATTTGGCCTTGCCCCCGTTTTGATTGGGCTCCCGTCTTGACCCATGGGC
GAGGCCGCGCGTATCCCTCC

Product: chorismate synthase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate phospholyase

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGIALTAEMIQVFLDKRRPGNGKFVTQRQEPDAVRILSGVFEDARSNGQ
RTTGTPISLMIENTDQRSKDYSEIAQAFRPGHADYAYFAKYGVRDYRGGGRSSARETAARVAAGAVARLIIPGVTVRAAL
VQIGPHKIDRSNWDWAQTEQNPYWSPDAAIVPVWEEHLEKIRKAGSSTGAVVEVEATGVPAGWGAPLYAKLDAELAAALM
SINAAKGVEIGDGFDSAALTGEDNADTMRMGDDGQPVFQSNHAGGILGGISSGQPIVARVAFKPTSSILIPRETVNEAGE
EIELRTKGRHDPCVGIRGVPVVEAMTACVLADAFLRHRGQTGREHFPLGASA

Sequences:

>Translated_372_residues
MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGIALTAEMIQVFLDKRRPGNGKFVTQRQEPDAVRILSGVFEDARSNGQ
RTTGTPISLMIENTDQRSKDYSEIAQAFRPGHADYAYFAKYGVRDYRGGGRSSARETAARVAAGAVARLIIPGVTVRAAL
VQIGPHKIDRSNWDWAQTEQNPYWSPDAAIVPVWEEHLEKIRKAGSSTGAVVEVEATGVPAGWGAPLYAKLDAELAAALM
SINAAKGVEIGDGFDSAALTGEDNADTMRMGDDGQPVFQSNHAGGILGGISSGQPIVARVAFKPTSSILIPRETVNEAGE
EIELRTKGRHDPCVGIRGVPVVEAMTACVLADAFLRHRGQTGREHFPLGASA
>Mature_371_residues
SHNTFGHLFRVTTWGESHGPALGCVVDGCPPGIALTAEMIQVFLDKRRPGNGKFVTQRQEPDAVRILSGVFEDARSNGQR
TTGTPISLMIENTDQRSKDYSEIAQAFRPGHADYAYFAKYGVRDYRGGGRSSARETAARVAAGAVARLIIPGVTVRAALV
QIGPHKIDRSNWDWAQTEQNPYWSPDAAIVPVWEEHLEKIRKAGSSTGAVVEVEATGVPAGWGAPLYAKLDAELAAALMS
INAAKGVEIGDGFDSAALTGEDNADTMRMGDDGQPVFQSNHAGGILGGISSGQPIVARVAFKPTSSILIPRETVNEAGEE
IELRTKGRHDPCVGIRGVPVVEAMTACVLADAFLRHRGQTGREHFPLGASA

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; seventh step. [C]

COG id: COG0082

COG function: function code E; Chorismate synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the chorismate synthase family

Homologues:

Organism=Escherichia coli, GI1788669, Length=364, Percent_Identity=59.8901098901099, Blast_Score=401, Evalue=1e-113,
Organism=Saccharomyces cerevisiae, GI6321290, Length=373, Percent_Identity=42.0911528150134, Blast_Score=277, Evalue=2e-75,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROC_CAUCN (B8H3W7)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002518629.1
- ProteinModelPortal:   B8H3W7
- SMR:   B8H3W7
- GeneID:   7330850
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_03256
- OMA:   SRFTTQR
- ProtClustDB:   PRK05382
- HAMAP:   MF_00300_B
- InterPro:   IPR000453
- InterPro:   IPR020541
- PANTHER:   PTHR21085
- PIRSF:   PIRSF001456
- TIGRFAMs:   TIGR00033

Pfam domain/function: PF01264 Chorismate_synt; SSF103263 Chorismate_synth

EC number: =4.2.3.5

Molecular weight: Translated: 39694; Mature: 39563

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: PS00787 CHORISMATE_SYNTHASE_1; PS00788 CHORISMATE_SYNTHASE_2; PS00789 CHORISMATE_SYNTHASE_3

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSHNTFGHLFRVTTWGESHGPALGCVVDGCPPGIALTAEMIQVFLDKRRPGNGKFVTQRQ
CCCCCCEEEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECC
EPDAVRILSGVFEDARSNGQRTTGTPISLMIENTDQRSKDYSEIAQAFRPGHADYAYFAK
CCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHH
YGVRDYRGGGRSSARETAARVAAGAVARLIIPGVTVRAALVQIGPHKIDRSNWDWAQTEQ
HCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
NPYWSPDAAIVPVWEEHLEKIRKAGSSTGAVVEVEATGVPAGWGAPLYAKLDAELAAALM
CCCCCCCCEEECHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHH
SINAAKGVEIGDGFDSAALTGEDNADTMRMGDDGQPVFQSNHAGGILGGISSGQPIVARV
HHHHHCCCCCCCCCCCCEECCCCCCCEEEECCCCCCCEECCCCCCEEECCCCCCCEEEEE
AFKPTSSILIPRETVNEAGEEIELRTKGRHDPCVGIRGVPVVEAMTACVLADAFLRHRGQ
EECCCCCEEECHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
TGREHFPLGASA
CCCCCCCCCCCC
>Mature Secondary Structure 
SHNTFGHLFRVTTWGESHGPALGCVVDGCPPGIALTAEMIQVFLDKRRPGNGKFVTQRQ
CCCCCEEEEEEEECCCCCCCEEEEEECCCCCCHHHHHHHHHHHHHHCCCCCCCEEEECC
EPDAVRILSGVFEDARSNGQRTTGTPISLMIENTDQRSKDYSEIAQAFRPGHADYAYFAK
CCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHHH
YGVRDYRGGGRSSARETAARVAAGAVARLIIPGVTVRAALVQIGPHKIDRSNWDWAQTEQ
HCCHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCCCCCCCCCCCCCC
NPYWSPDAAIVPVWEEHLEKIRKAGSSTGAVVEVEATGVPAGWGAPLYAKLDAELAAALM
CCCCCCCCEEECHHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCEEEEHHHHHHHHHH
SINAAKGVEIGDGFDSAALTGEDNADTMRMGDDGQPVFQSNHAGGILGGISSGQPIVARV
HHHHHCCCCCCCCCCCCEECCCCCCCEEEECCCCCCCEECCCCCCEEECCCCCCCEEEEE
AFKPTSSILIPRETVNEAGEEIELRTKGRHDPCVGIRGVPVVEAMTACVLADAFLRHRGQ
EECCCCCEEECHHHHHHCCCEEEEEECCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCC
TGREHFPLGASA
CCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA