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The map label for this gene is sdaA [H]

Identifier: 16127338

GI number: 16127338

Start: 3342275

End: 3343663

Strand: Direct

Name: sdaA [H]

Synonym: CC_3108

Alternate gene names: 16127338

Gene position: 3342275-3343663 (Clockwise)

Preceding gene: 16127337

Following gene: 16127339

Centisome position: 83.2

GC content: 69.47

Gene sequence:

>1389_bases
ATGACCGCCTCCGTCTTCGACCTCTTCAAGCTCGGCGTCGGCCCGTCGAGCAGCCACACCATGGGGCCGATGACGGCCGC
CGTGCTGTTCATCGGCCGCCTGCGCGACGCCGGTAAACTGGCCGCCGTCGCGCGGGTGGAGACGCGGCTCTACGCCTCGC
TGGCCCTGACCGGTCGCGGTCACGCCACCGATCGCGCGGTGATCCTGGGTCTGATGGGCTTCGTGCCCGCTGACCTCGAT
CCCGACGCGGGTGAAGCGGCGCTGCTGGACTGTCAGGCCAGCCAGTCGCTGAAGCTGGGCGGTGAGGTCGATATCGCCTT
CGACGAGGCGCGAGACATCGTCTGGCTGGGCCATGAGCGCCTGCCGCAGCATCCCAACGCCCTGACCTTCGCCGCCTATG
ACAAGGCCGGTCAGGTCCTGGCCGAGCGCACCTATTTCTCGATCGGCGGCGGCTTTGTCCGTGACGAGGCCGAGATGGGC
CGCAACGCCCCGCCAGACGAAGGCCCCGCCATCCCCTTCCCGTTCGAAAGCGCCGCCGACCTGCTGGAACGCGCCGAGCA
GGCGGGTCTCTCCATCGCCGAGGTCATGGCCGCCAACGAGCGCGCGCGGATGAGCCAGGGCGAGATGGACGCCGGCCTCG
ACCGCATCTTCGGCGCCATGGAGGCCTGTATCGATCGCGGCATGCGCCAGGAGGGCGTCCTGCCGGGCGGCCTCACCGTC
AAGCGCCGCGCCCGCCAGATCCATCAGACCATCCAGGGCCGGATGGAGCGCCAGATGAGCGATCCGCTGGCGGCGATGGA
CTTCGTCAACCTGTGGGCCATGGCGGTCAACGAAGAGAACGCCGCCGGCGGCCGCGTCGTCACCGCCCCAACCAACGGCG
CGGCGGGGCTGATCCCGGCCGTGCTGCGGTTCTTCGTCAGGTTCTACAAGGGCACGCCCGAGCAGATCCGCACGTTCCTG
CTGACCGCCGCGGCGATCGGCGCGCTCTACAAACGCAACGCCTCGATCAGCGGCGCCGAGGTCGGCTGCCAGGGCGAGGT
GGGCGTGGCCTGCTCGATGGCGGCGGCGGGCCTGGCGGCCGCGCTGGGCGGGACCAACGCCCAGATCGAGAACGCCGCCG
AGATCGGCATGGAGCACAATCTCGGCCTCACCTGCGACCCGATCGGGGGTCTGGTGCAGATCCCCTGCATCGAGCGCAAC
GCCATGGGCGCCATCAAGGCCATCGACGCCGCCCGTCTGGCCTTGCTGGGCGACGGCCAGCACTCGGTGTCGCTGGACAA
GGTGATCGCCACCATGAAGCGCACCGGCGAGGACATGAACGAGATCTACAAGGAAACCTCGATGGGGGGTCTGGCGGTGG
GTCTGTCGGTGAACCGGGTGGAGTGTTGA

Upstream 100 bases:

>100_bases
GGCCTTACCCGCCCGGCAGACGCTTATGGGTTCGATCTGGACCCCGGCATTCGCCGGGGAGGTCGGATTTGATGAGCGCG
GAGATATTCAAAGTTCCCCC

Downstream 100 bases:

>100_bases
TCACTCGCCCCCTCCGGGCCTGACGGCCCTCCTCCCCCGGAGGGGGAAGAAGGGCTCCTTCCGCCCCCGCTGGGGGCGGA
CGACCTCGCAACGCGAGGTC

Product: L-serine dehydratase

Products: NA

Alternate protein names: SDH; L-serine deaminase; L-SD [H]

Number of amino acids: Translated: 462; Mature: 461

Protein sequence:

>462_residues
MTASVFDLFKLGVGPSSSHTMGPMTAAVLFIGRLRDAGKLAAVARVETRLYASLALTGRGHATDRAVILGLMGFVPADLD
PDAGEAALLDCQASQSLKLGGEVDIAFDEARDIVWLGHERLPQHPNALTFAAYDKAGQVLAERTYFSIGGGFVRDEAEMG
RNAPPDEGPAIPFPFESAADLLERAEQAGLSIAEVMAANERARMSQGEMDAGLDRIFGAMEACIDRGMRQEGVLPGGLTV
KRRARQIHQTIQGRMERQMSDPLAAMDFVNLWAMAVNEENAAGGRVVTAPTNGAAGLIPAVLRFFVRFYKGTPEQIRTFL
LTAAAIGALYKRNASISGAEVGCQGEVGVACSMAAAGLAAALGGTNAQIENAAEIGMEHNLGLTCDPIGGLVQIPCIERN
AMGAIKAIDAARLALLGDGQHSVSLDKVIATMKRTGEDMNEIYKETSMGGLAVGLSVNRVEC

Sequences:

>Translated_462_residues
MTASVFDLFKLGVGPSSSHTMGPMTAAVLFIGRLRDAGKLAAVARVETRLYASLALTGRGHATDRAVILGLMGFVPADLD
PDAGEAALLDCQASQSLKLGGEVDIAFDEARDIVWLGHERLPQHPNALTFAAYDKAGQVLAERTYFSIGGGFVRDEAEMG
RNAPPDEGPAIPFPFESAADLLERAEQAGLSIAEVMAANERARMSQGEMDAGLDRIFGAMEACIDRGMRQEGVLPGGLTV
KRRARQIHQTIQGRMERQMSDPLAAMDFVNLWAMAVNEENAAGGRVVTAPTNGAAGLIPAVLRFFVRFYKGTPEQIRTFL
LTAAAIGALYKRNASISGAEVGCQGEVGVACSMAAAGLAAALGGTNAQIENAAEIGMEHNLGLTCDPIGGLVQIPCIERN
AMGAIKAIDAARLALLGDGQHSVSLDKVIATMKRTGEDMNEIYKETSMGGLAVGLSVNRVEC
>Mature_461_residues
TASVFDLFKLGVGPSSSHTMGPMTAAVLFIGRLRDAGKLAAVARVETRLYASLALTGRGHATDRAVILGLMGFVPADLDP
DAGEAALLDCQASQSLKLGGEVDIAFDEARDIVWLGHERLPQHPNALTFAAYDKAGQVLAERTYFSIGGGFVRDEAEMGR
NAPPDEGPAIPFPFESAADLLERAEQAGLSIAEVMAANERARMSQGEMDAGLDRIFGAMEACIDRGMRQEGVLPGGLTVK
RRARQIHQTIQGRMERQMSDPLAAMDFVNLWAMAVNEENAAGGRVVTAPTNGAAGLIPAVLRFFVRFYKGTPEQIRTFLL
TAAAIGALYKRNASISGAEVGCQGEVGVACSMAAAGLAAALGGTNAQIENAAEIGMEHNLGLTCDPIGGLVQIPCIERNA
MGAIKAIDAARLALLGDGQHSVSLDKVIATMKRTGEDMNEIYKETSMGGLAVGLSVNRVEC

Specific function: Deaminates Also Threonine, Particularly When It Is Present In High Concentration. [C]

COG id: COG1760

COG function: function code E; L-serine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the iron-sulfur dependent L-serine dehydratase family [H]

Homologues:

Organism=Escherichia coli, GI1788116, Length=463, Percent_Identity=50.5399568034557, Blast_Score=437, Evalue=1e-124,
Organism=Escherichia coli, GI48994925, Length=452, Percent_Identity=51.7699115044248, Blast_Score=435, Evalue=1e-123,
Organism=Escherichia coli, GI1789161, Length=457, Percent_Identity=49.2341356673961, Blast_Score=418, Evalue=1e-118,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004644
- InterPro:   IPR005130
- InterPro:   IPR005131 [H]

Pfam domain/function: PF03313 SDH_alpha; PF03315 SDH_beta [H]

EC number: =4.3.1.17 [H]

Molecular weight: Translated: 48660; Mature: 48529

Theoretical pI: Translated: 4.92; Mature: 4.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
4.1 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTASVFDLFKLGVGPSSSHTMGPMTAAVLFIGRLRDAGKLAAVARVETRLYASLALTGRG
CCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCC
HATDRAVILGLMGFVPADLDPDAGEAALLDCQASQSLKLGGEVDIAFDEARDIVWLGHER
CCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEECHHH
LPQHPNALTFAAYDKAGQVLAERTYFSIGGGFVRDEAEMGRNAPPDEGPAIPFPFESAAD
CCCCCCCEEEEEHHHHHHHHHHHHEEECCCCEEECHHHHCCCCCCCCCCCCCCCHHHHHH
LLERAEQAGLSIAEVMAANERARMSQGEMDAGLDRIFGAMEACIDRGMRQEGVLPGGLTV
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHH
KRRARQIHQTIQGRMERQMSDPLAAMDFVNLWAMAVNEENAAGGRVVTAPTNGAAGLIPA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHH
VLRFFVRFYKGTPEQIRTFLLTAAAIGALYKRNASISGAEVGCQGEVGVACSMAAAGLAA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ALGGTNAQIENAAEIGMEHNLGLTCDPIGGLVQIPCIERNAMGAIKAIDAARLALLGDGQ
HHCCCCCCHHHHHHHCCCCCCCEEECCCCCEEECCEECCCCCHHHHHHHHHHEEEEECCC
HSVSLDKVIATMKRTGEDMNEIYKETSMGGLAVGLSVNRVEC
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCC
>Mature Secondary Structure 
TASVFDLFKLGVGPSSSHTMGPMTAAVLFIGRLRDAGKLAAVARVETRLYASLALTGRG
CCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHEEECCCC
HATDRAVILGLMGFVPADLDPDAGEAALLDCQASQSLKLGGEVDIAFDEARDIVWLGHER
CCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCCEEEEEECCCCCEEEECHHH
LPQHPNALTFAAYDKAGQVLAERTYFSIGGGFVRDEAEMGRNAPPDEGPAIPFPFESAAD
CCCCCCCEEEEEHHHHHHHHHHHHEEECCCCEEECHHHHCCCCCCCCCCCCCCCHHHHHH
LLERAEQAGLSIAEVMAANERARMSQGEMDAGLDRIFGAMEACIDRGMRQEGVLPGGLTV
HHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHCCCHHCCCCCCCCHH
KRRARQIHQTIQGRMERQMSDPLAAMDFVNLWAMAVNEENAAGGRVVTAPTNGAAGLIPA
HHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCCCHHHHH
VLRFFVRFYKGTPEQIRTFLLTAAAIGALYKRNASISGAEVGCQGEVGVACSMAAAGLAA
HHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCHHHHHHHHHHHH
ALGGTNAQIENAAEIGMEHNLGLTCDPIGGLVQIPCIERNAMGAIKAIDAARLALLGDGQ
HHCCCCCCHHHHHHHCCCCCCCEEECCCCCEEECCEECCCCCHHHHHHHHHHEEEEECCC
HSVSLDKVIATMKRTGEDMNEIYKETSMGGLAVGLSVNRVEC
CCHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12000953 [H]