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The map label for this gene is aroB

Identifier: 16127239

GI number: 16127239

Start: 3228555

End: 3229667

Strand: Direct

Name: aroB

Synonym: CC_3009

Alternate gene names: 16127239

Gene position: 3228555-3229667 (Clockwise)

Preceding gene: 16127238

Following gene: 16127241

Centisome position: 80.37

GC content: 70.53

Gene sequence:

>1113_bases
ATGATCCGCACCGTCCCCGTGGGCCTGGGCGAGCGCGCCTATGACGTCGTCATCGGGCCTGGCCTGCTGGATCAGGCCGG
CGAGCGTGTCGCCGCCGTGCTGGGCAAGCGCAAGCGCGTCGCCGTCGTCACCGACGCCCATGTCGGCGCCCATCACGGCG
AGCGTCTCTCCGCCGCGCTGCAAGGCGCCGGGATCACCGTCGACCTCATCACCATCGCGCCCGGCGAGGAGAGCAAGAGC
TTCGAGGGCCTGGCCGATCTCTCCGACCGCCTGCTGGCCTTGAACCTGGAGCGCGGCGACCAGATCGTGGCCCTGGGCGG
CGGCGTCGTGGGCGACCTCGCCGGCTTTGCGGCGGCGATCTACAAGCGCGGCATCGACTTCGTGCAGGTCCCGACCACCC
TGCTGGCCCAGGTCGACAGCTCGGTGGGCGGCAAGACCGCCATCGACACCCCGCGCGGCAAGAACCTGATCGGGGCCTTC
CACCAGCCGCGCCTGGTTCTGGCCGACCTCGATGTGCTGGCCACCCTGCCCGCCCGCGAGCTGGCCTGCGGCTATGCCGA
GATCATCAAGTACGGCCTCCTGGGGGACTTCGCCTTCTTCGAATGGCTGGAGACCAACGTCCAGGCGGTGCTGGACCGCG
ACGTCGACGCTCTGGTGCGCGCCGTCGGCCGCAGCGTCGAGATGAAGGCCGAGATCGTCGCCGAGGACGAAAAGGAAGCC
GGACGCCGCGCGCTCTTGAATCTCGGCCATACCTTCGGTCACGCCATCGAGGCCGAGATGGGCTTTGGCGAGGCGCTCAA
GCACGGCGAGGCCGTCGGGGTGGGCATGGCCCAGGCGTTCCGCTTCTCGGCCAGGCTCGGCCTCTGCCCCAGCCAGGACG
CGGTGCGCGCGCAGGCGGCCATCAAGGCCGCCGGCCTGCCGACCACGCTGGCCGATGTGCGCCCCGAGCCCTTCAGCGCC
GACGCCCTGATCGCTCACTGCGGCCAGGACAAGAAGGCGCAAGGCGGCAAGCTGACCTTCGTGCTGGCGCGCGGCATCGG
CGATGCGTTCGTCGCCAAGGACGTCGATCGCGCGGCGCTGAAGGCGTTCCTGGTTGAGGAAGGCGCGGTCTAG

Upstream 100 bases:

>100_bases
CGAGGCGCAAGTCCATGTCGAGACCGGCGACACCCCCCACATGGTGGCGGTCGAGGCCATTCTGACGGCGCTGCGTCAGG
CCCACGCTTAAGGAGTTCGC

Downstream 100 bases:

>100_bases
GAGCCTGTCGGGTTTCGAGGGAACCCTCTCAACCCGACAATCCAAGACGCGGTGTCATCCCGGCCGGAAGACCGCGCAGC
GGGCTGTAGAGCCGGGACCC

Product: 3-dehydroquinate synthase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 370; Mature: 370

Protein sequence:

>370_residues
MIRTVPVGLGERAYDVVIGPGLLDQAGERVAAVLGKRKRVAVVTDAHVGAHHGERLSAALQGAGITVDLITIAPGEESKS
FEGLADLSDRLLALNLERGDQIVALGGGVVGDLAGFAAAIYKRGIDFVQVPTTLLAQVDSSVGGKTAIDTPRGKNLIGAF
HQPRLVLADLDVLATLPARELACGYAEIIKYGLLGDFAFFEWLETNVQAVLDRDVDALVRAVGRSVEMKAEIVAEDEKEA
GRRALLNLGHTFGHAIEAEMGFGEALKHGEAVGVGMAQAFRFSARLGLCPSQDAVRAQAAIKAAGLPTTLADVRPEPFSA
DALIAHCGQDKKAQGGKLTFVLARGIGDAFVAKDVDRAALKAFLVEEGAV

Sequences:

>Translated_370_residues
MIRTVPVGLGERAYDVVIGPGLLDQAGERVAAVLGKRKRVAVVTDAHVGAHHGERLSAALQGAGITVDLITIAPGEESKS
FEGLADLSDRLLALNLERGDQIVALGGGVVGDLAGFAAAIYKRGIDFVQVPTTLLAQVDSSVGGKTAIDTPRGKNLIGAF
HQPRLVLADLDVLATLPARELACGYAEIIKYGLLGDFAFFEWLETNVQAVLDRDVDALVRAVGRSVEMKAEIVAEDEKEA
GRRALLNLGHTFGHAIEAEMGFGEALKHGEAVGVGMAQAFRFSARLGLCPSQDAVRAQAAIKAAGLPTTLADVRPEPFSA
DALIAHCGQDKKAQGGKLTFVLARGIGDAFVAKDVDRAALKAFLVEEGAV
>Mature_370_residues
MIRTVPVGLGERAYDVVIGPGLLDQAGERVAAVLGKRKRVAVVTDAHVGAHHGERLSAALQGAGITVDLITIAPGEESKS
FEGLADLSDRLLALNLERGDQIVALGGGVVGDLAGFAAAIYKRGIDFVQVPTTLLAQVDSSVGGKTAIDTPRGKNLIGAF
HQPRLVLADLDVLATLPARELACGYAEIIKYGLLGDFAFFEWLETNVQAVLDRDVDALVRAVGRSVEMKAEIVAEDEKEA
GRRALLNLGHTFGHAIEAEMGFGEALKHGEAVGVGMAQAFRFSARLGLCPSQDAVRAQAAIKAAGLPTTLADVRPEPFSA
DALIAHCGQDKKAQGGKLTFVLARGIGDAFVAKDVDRAALKAFLVEEGAV

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; second step. [C]

COG id: COG0337

COG function: function code E; 3-dehydroquinate synthetase

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the dehydroquinate synthase family

Homologues:

Organism=Escherichia coli, GI1789791, Length=350, Percent_Identity=48.8571428571429, Blast_Score=294, Evalue=5e-81,
Organism=Saccharomyces cerevisiae, GI6320332, Length=336, Percent_Identity=38.0952380952381, Blast_Score=197, Evalue=3e-51,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROB_CAUCN (B8H332)

Other databases:

- EMBL:   CP001340
- RefSeq:   YP_002518477.1
- ProteinModelPortal:   B8H332
- SMR:   B8H332
- GeneID:   7333558
- GenomeReviews:   CP001340_GR
- KEGG:   ccs:CCNA_03104
- OMA:   GWIDESI
- ProtClustDB:   PRK00002
- GO:   GO:0005737
- HAMAP:   MF_00110
- InterPro:   IPR016303
- InterPro:   IPR002658
- InterPro:   IPR016037
- PANTHER:   PTHR21090:SF1
- PIRSF:   PIRSF001455
- TIGRFAMs:   TIGR01357

Pfam domain/function: PF01761 DHQ_synthase

EC number: =4.2.3.4

Molecular weight: Translated: 38727; Mature: 38727

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.9 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRTVPVGLGERAYDVVIGPGLLDQAGERVAAVLGKRKRVAVVTDAHVGAHHGERLSAAL
CCEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHH
QGAGITVDLITIAPGEESKSFEGLADLSDRLLALNLERGDQIVALGGGVVGDLAGFAAAI
CCCCCEEEEEEECCCCCCCCCCCHHHHCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHH
YKRGIDFVQVPTTLLAQVDSSVGGKTAIDTPRGKNLIGAFHQPRLVLADLDVLATLPARE
HHCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCEEEEECHHHHHHCCHHH
LACGYAEIIKYGLLGDFAFFEWLETNVQAVLDRDVDALVRAVGRSVEMKAEIVAEDEKEA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEHHEEECCHHHH
GRRALLNLGHTFGHAIEAEMGFGEALKHGEAVGVGMAQAFRFSARLGLCPSQDAVRAQAA
HHHHHHHHHHHHHHHHECCCCHHHHHHCCCHHCHHHHHHHHHHHHCCCCCCHHHHHHHHH
IKAAGLPTTLADVRPEPFSADALIAHCGQDKKAQGGKLTFVLARGIGDAFVAKDVDRAAL
HHHCCCCCHHHHCCCCCCCCCHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
KAFLVEEGAV
HHHHHHCCCC
>Mature Secondary Structure
MIRTVPVGLGERAYDVVIGPGLLDQAGERVAAVLGKRKRVAVVTDAHVGAHHGERLSAAL
CCEEECCCCCCCCEEEEECCCHHHHHHHHHHHHHCCCCEEEEEEECCCCCCCCHHHHHHH
QGAGITVDLITIAPGEESKSFEGLADLSDRLLALNLERGDQIVALGGGVVGDLAGFAAAI
CCCCCEEEEEEECCCCCCCCCCCHHHHCCCEEEEEECCCCEEEEECCCHHHHHHHHHHHH
YKRGIDFVQVPTTLLAQVDSSVGGKTAIDTPRGKNLIGAFHQPRLVLADLDVLATLPARE
HHCCCCEEEHHHHHHHHHHHCCCCCCCCCCCCCCCHHCCCCCCEEEEECHHHHHHCCHHH
LACGYAEIIKYGLLGDFAFFEWLETNVQAVLDRDVDALVRAVGRSVEMKAEIVAEDEKEA
HHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCEEEHHEEECCHHHH
GRRALLNLGHTFGHAIEAEMGFGEALKHGEAVGVGMAQAFRFSARLGLCPSQDAVRAQAA
HHHHHHHHHHHHHHHHECCCCHHHHHHCCCHHCHHHHHHHHHHHHCCCCCCHHHHHHHHH
IKAAGLPTTLADVRPEPFSADALIAHCGQDKKAQGGKLTFVLARGIGDAFVAKDVDRAAL
HHHCCCCCHHHHCCCCCCCCCHHHHHCCCCCCCCCCEEEEEEECCCCCHHHHHHHHHHHH
KAFLVEEGAV
HHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA