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The map label for this gene is luxQ [H]

Identifier: 16127223

GI number: 16127223

Start: 3210923

End: 3212797

Strand: Direct

Name: luxQ [H]

Synonym: CC_2993

Alternate gene names: 16127223

Gene position: 3210923-3212797 (Clockwise)

Preceding gene: 16127222

Following gene: 16127226

Centisome position: 79.93

GC content: 70.29

Gene sequence:

>1875_bases
ATGACTAGCGCCGTCATCCCGTTTTCGCCCGCGCAGGTCGACGCCGCCTCGGACCGCGAAGCGCGCATCGCCCGTCTCGA
ACGCCGGCTGAGCCGCGAACTGCTGGCGCGTCGCGAGGCTGAAGCGATCGCCGAGGCGGCGACCCATCGCCTCTATCGGC
AAGGCGAGCGGATGCGGCTCCTGGCGGACCTGGCGCTTGAGGCCAATCGCAGCGACGATCTCGACACCGTCCTGCGCGCC
GCGCTCAGGGCGATCGGAAGCCAGACGGGCTGGCCCGTCGGACACGTCCAACTGGTCGAGACCGACGCCGAGGCGATGGA
CTGGCTGCAACCCACGGCGTTGTGGCTGGCCCCGCCCGACACGGACATCGCAGCGCTTCGGCGGGCGACCACGCCGCGCC
GCGCCCAGATCGGCGGCGGCGTGCTCGGCCAAGTGATGCGGCTGCGCGGCGCCTGCACCATCGAGAGCCTCGCCAGTTGC
CCGGCCGAGCGCCGGCGCGCCGCAAGCGCCCTAGGCCTCAATCAGGGCGTCGGCTTTCCCATTCTGGTCGGCGACGAGAT
CGCTGCGGTCGTCGAGTTCTTTCACGACCATGGCCGAGGCCCCGACGCGGAGACGCTCGCCTTTCTCGACCAGATCGGCG
CGGTGCTGGGGCGAGCCTTCGAGCGGCGCAGGGCCGAGCGGGCCGCCCAGGAGGCCCGCGCGCGGCTTGAGGAAAGCCTT
GCAGCCGCCGAGGCGGCCAGCCGGGCCAAAACCCATCTCCTGGCGGTCGCCAGCCATGAGGTTCGCACGCCGCTGAACGC
GGTGCTCGGGCTGGCGGAGGTCCTTGCCCGAAGCCCTCTGGACGCGACACAGCGCGAGCATGTCGACGGTGTGCGCCAGG
CCGGCGGCATGCTCCTGCGCCTGTTGAGCTCGGTTCTGGATTTCGCCCGCATCGAAAGCGGCGCCACGCCGCTGGTCCCC
GCCCCCTTCAACCTCGCCGATCTGGCGCGCGAGGTAACCGGTGTCTGGCGCGCTGCGGCCGGCGCCGCGCAGCTTGACCT
TCACCTGGACCTCTCGGCCTGCCCTGACCCCTGCTGGATTTCGGCGGACAGCGGCAAGATCGAGCAAACCCTGACCAACC
TCGTCTCCAACGCCATCAAGTTCACGCCCGCCGGCGGCAAGATCCTGGTCCGCGTTGAAACGACGCCGAGTGCGTCACCG
ACCTTCCGCATTGTGGTCGAGGACAGCGGCGCGGGCGTGCCGGCGGAGGACATCGATCGGATCTTCGACCCCTTCCAGCA
AGCCGCGCTGGGACGCGAGGTCGGCGGCGCGGGGCTTGGCCTGGCGATCTGCGCGGCGAACCTGCGCGCCATGGGCGGCG
ACATTGGCTATCAGCCGGCGCCCGAGCGGGGTTCGCAGTTCTGGTTCAGCTTCGTGGCCGAGGCCGTCGACGCCCAGGCC
GAGCCTGCGAAGGTCGATGCGCTGACCGACCTGCCGCTGCGGATTCTGGCGGCCGAGGACAATCCCGCCAACCAGCGCGT
CCTGCGTTTGCTGCTGGAGCAGGTCGGCATTACGCCAACCGTTGTCGAAGACGGCGCCGCTGCGGTGGAGGCGGCGCGGT
CGACACCGTTCGACCTCATCCTGATGGACGCCAACATGCCGCGAATGGATGGTCCGGCCGCCGTCGAGGCGATCCGCGCT
CTGGGTATCGGCAAGGACCGCACGCCGATCGTCATGCTGACGGCCAATGTTTTCGAGGACGACGTCCGCCGCTACCGAGC
CGCGGGCGCGGACGGGGTCCTGGCCAAGCCGCTCGCGGTCGCCGAGCTGTACGCGGTGCTCGCTGAAGTTCAGAACCGCG
TCGCTGGCGAAGGCCTAGAGCCCTTTCCGATCTGA

Upstream 100 bases:

>100_bases
TTTCACGAGGTCATCACCTTTGAACACGCCGCGTGCGTGGAAAAGGGCGACAGCGCCTGTGTCTTCCACATCGGCTGGCC
GTCGCTAGAGGCGGCGGCGA

Downstream 100 bases:

>100_bases
TTGAACCAATCAGATCGGATAAAAAGGGCTCTAGCGATCTGAATCAGGGCTGGAGCAGTTCTTCCAGCGCCTGGGCCCGG
CGCGCCGTGTGCTTCAGATA

Product: sensor histidine kinase/response regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 624; Mature: 623

Protein sequence:

>624_residues
MTSAVIPFSPAQVDAASDREARIARLERRLSRELLARREAEAIAEAATHRLYRQGERMRLLADLALEANRSDDLDTVLRA
ALRAIGSQTGWPVGHVQLVETDAEAMDWLQPTALWLAPPDTDIAALRRATTPRRAQIGGGVLGQVMRLRGACTIESLASC
PAERRRAASALGLNQGVGFPILVGDEIAAVVEFFHDHGRGPDAETLAFLDQIGAVLGRAFERRRAERAAQEARARLEESL
AAAEAASRAKTHLLAVASHEVRTPLNAVLGLAEVLARSPLDATQREHVDGVRQAGGMLLRLLSSVLDFARIESGATPLVP
APFNLADLAREVTGVWRAAAGAAQLDLHLDLSACPDPCWISADSGKIEQTLTNLVSNAIKFTPAGGKILVRVETTPSASP
TFRIVVEDSGAGVPAEDIDRIFDPFQQAALGREVGGAGLGLAICAANLRAMGGDIGYQPAPERGSQFWFSFVAEAVDAQA
EPAKVDALTDLPLRILAAEDNPANQRVLRLLLEQVGITPTVVEDGAAAVEAARSTPFDLILMDANMPRMDGPAAVEAIRA
LGIGKDRTPIVMLTANVFEDDVRRYRAAGADGVLAKPLAVAELYAVLAEVQNRVAGEGLEPFPI

Sequences:

>Translated_624_residues
MTSAVIPFSPAQVDAASDREARIARLERRLSRELLARREAEAIAEAATHRLYRQGERMRLLADLALEANRSDDLDTVLRA
ALRAIGSQTGWPVGHVQLVETDAEAMDWLQPTALWLAPPDTDIAALRRATTPRRAQIGGGVLGQVMRLRGACTIESLASC
PAERRRAASALGLNQGVGFPILVGDEIAAVVEFFHDHGRGPDAETLAFLDQIGAVLGRAFERRRAERAAQEARARLEESL
AAAEAASRAKTHLLAVASHEVRTPLNAVLGLAEVLARSPLDATQREHVDGVRQAGGMLLRLLSSVLDFARIESGATPLVP
APFNLADLAREVTGVWRAAAGAAQLDLHLDLSACPDPCWISADSGKIEQTLTNLVSNAIKFTPAGGKILVRVETTPSASP
TFRIVVEDSGAGVPAEDIDRIFDPFQQAALGREVGGAGLGLAICAANLRAMGGDIGYQPAPERGSQFWFSFVAEAVDAQA
EPAKVDALTDLPLRILAAEDNPANQRVLRLLLEQVGITPTVVEDGAAAVEAARSTPFDLILMDANMPRMDGPAAVEAIRA
LGIGKDRTPIVMLTANVFEDDVRRYRAAGADGVLAKPLAVAELYAVLAEVQNRVAGEGLEPFPI
>Mature_623_residues
TSAVIPFSPAQVDAASDREARIARLERRLSRELLARREAEAIAEAATHRLYRQGERMRLLADLALEANRSDDLDTVLRAA
LRAIGSQTGWPVGHVQLVETDAEAMDWLQPTALWLAPPDTDIAALRRATTPRRAQIGGGVLGQVMRLRGACTIESLASCP
AERRRAASALGLNQGVGFPILVGDEIAAVVEFFHDHGRGPDAETLAFLDQIGAVLGRAFERRRAERAAQEARARLEESLA
AAEAASRAKTHLLAVASHEVRTPLNAVLGLAEVLARSPLDATQREHVDGVRQAGGMLLRLLSSVLDFARIESGATPLVPA
PFNLADLAREVTGVWRAAAGAAQLDLHLDLSACPDPCWISADSGKIEQTLTNLVSNAIKFTPAGGKILVRVETTPSASPT
FRIVVEDSGAGVPAEDIDRIFDPFQQAALGREVGGAGLGLAICAANLRAMGGDIGYQPAPERGSQFWFSFVAEAVDAQAE
PAKVDALTDLPLRILAAEDNPANQRVLRLLLEQVGITPTVVEDGAAAVEAARSTPFDLILMDANMPRMDGPAAVEAIRAL
GIGKDRTPIVMLTANVFEDDVRRYRAAGADGVLAKPLAVAELYAVLAEVQNRVAGEGLEPFPI

Specific function: At low cell density, in absence of autoinducer has a kinase activity, and autophosphorylates on a histidine residue. The phosphoryl group is then transferred to an aspartate residue in the response regulator domain. The phosphoryl group is transferred to

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=382, Percent_Identity=32.4607329842932, Blast_Score=177, Evalue=2e-45,
Organism=Escherichia coli, GI1788713, Length=381, Percent_Identity=31.496062992126, Blast_Score=167, Evalue=2e-42,
Organism=Escherichia coli, GI1789149, Length=233, Percent_Identity=37.3390557939914, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI87081816, Length=417, Percent_Identity=32.8537170263789, Blast_Score=160, Evalue=3e-40,
Organism=Escherichia coli, GI145693157, Length=314, Percent_Identity=31.5286624203822, Blast_Score=147, Evalue=2e-36,
Organism=Escherichia coli, GI1786600, Length=227, Percent_Identity=28.1938325991189, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI1786912, Length=242, Percent_Identity=31.8181818181818, Blast_Score=84, Evalue=3e-17,
Organism=Escherichia coli, GI1788549, Length=236, Percent_Identity=28.8135593220339, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI1788393, Length=217, Percent_Identity=27.1889400921659, Blast_Score=79, Evalue=6e-16,
Organism=Escherichia coli, GI1790861, Length=244, Percent_Identity=26.2295081967213, Blast_Score=77, Evalue=4e-15,
Organism=Escherichia coli, GI1786783, Length=218, Percent_Identity=27.9816513761468, Blast_Score=76, Evalue=6e-15,
Organism=Escherichia coli, GI1790436, Length=259, Percent_Identity=27.4131274131274, Blast_Score=70, Evalue=3e-13,
Organism=Escherichia coli, GI1790346, Length=233, Percent_Identity=28.755364806867, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI87082128, Length=227, Percent_Identity=28.6343612334802, Blast_Score=66, Evalue=6e-12,
Organism=Saccharomyces cerevisiae, GI6322000, Length=115, Percent_Identity=31.304347826087, Blast_Score=75, Evalue=3e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR015387
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789
- ProDom:   PD142495 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF09308 LuxQ-periplasm; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66419; Mature: 66288

Theoretical pI: Translated: 4.87; Mature: 4.87

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTSAVIPFSPAQVDAASDREARIARLERRLSRELLARREAEAIAEAATHRLYRQGERMRL
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LADLALEANRSDDLDTVLRAALRAIGSQTGWPVGHVQLVETDAEAMDWLQPTALWLAPPD
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCEEEECCCC
TDIAALRRATTPRRAQIGGGVLGQVMRLRGACTIESLASCPAERRRAASALGLNQGVGFP
CHHHHHHHCCCCCHHHHCCHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCE
ILVGDEIAAVVEFFHDHGRGPDAETLAFLDQIGAVLGRAFERRRAERAAQEARARLEESL
EEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAEAASRAKTHLLAVASHEVRTPLNAVLGLAEVLARSPLDATQREHVDGVRQAGGMLLR
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LLSSVLDFARIESGATPLVPAPFNLADLAREVTGVWRAAAGAAQLDLHLDLSACPDPCWI
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEE
SADSGKIEQTLTNLVSNAIKFTPAGGKILVRVETTPSASPTFRIVVEDSGAGVPAEDIDR
CCCCCHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHH
IFDPFQQAALGREVGGAGLGLAICAANLRAMGGDIGYQPAPERGSQFWFSFVAEAVDAQA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
EPAKVDALTDLPLRILAAEDNPANQRVLRLLLEQVGITPTVVEDGAAAVEAARSTPFDLI
CCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCCCEEE
LMDANMPRMDGPAAVEAIRALGIGKDRTPIVMLTANVFEDDVRRYRAAGADGVLAKPLAV
EECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHH
AELYAVLAEVQNRVAGEGLEPFPI
HHHHHHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
TSAVIPFSPAQVDAASDREARIARLERRLSRELLARREAEAIAEAATHRLYRQGERMRL
CCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHH
LADLALEANRSDDLDTVLRAALRAIGSQTGWPVGHVQLVETDAEAMDWLQPTALWLAPPD
HHHHHHHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEEEECCHHHHHHHCCCEEEECCCC
TDIAALRRATTPRRAQIGGGVLGQVMRLRGACTIESLASCPAERRRAASALGLNQGVGFP
CHHHHHHHCCCCCHHHHCCHHHHHHHHHHCCCCHHHHHCCCHHHHHHHHHHCCCCCCCCE
ILVGDEIAAVVEFFHDHGRGPDAETLAFLDQIGAVLGRAFERRRAERAAQEARARLEESL
EEECHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAAEAASRAKTHLLAVASHEVRTPLNAVLGLAEVLARSPLDATQREHVDGVRQAGGMLLR
HHHHHHHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHH
LLSSVLDFARIESGATPLVPAPFNLADLAREVTGVWRAAAGAAQLDLHLDLSACPDPCWI
HHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEEEEECCCCCCCCEE
SADSGKIEQTLTNLVSNAIKFTPAGGKILVRVETTPSASPTFRIVVEDSGAGVPAEDIDR
CCCCCHHHHHHHHHHHHHEEECCCCCEEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHH
IFDPFQQAALGREVGGAGLGLAICAANLRAMGGDIGYQPAPERGSQFWFSFVAEAVDAQA
HHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCC
EPAKVDALTDLPLRILAAEDNPANQRVLRLLLEQVGITPTVVEDGAAAVEAARSTPFDLI
CCCHHHHHCCCCEEEEEECCCCHHHHHHHHHHHHHCCCCEEECCCHHHHHHHCCCCCEEE
LMDANMPRMDGPAAVEAIRALGIGKDRTPIVMLTANVFEDDVRRYRAAGADGVLAKPLAV
EECCCCCCCCCHHHHHHHHHHCCCCCCCCEEEEEHHHHHHHHHHHHHCCCCCCHHHHHHH
AELYAVLAEVQNRVAGEGLEPFPI
HHHHHHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA