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The map label for this gene is mcpA [H]

Identifier: 16127079

GI number: 16127079

Start: 3073804

End: 3075408

Strand: Direct

Name: mcpA [H]

Synonym: CC_2847

Alternate gene names: 16127079

Gene position: 3073804-3075408 (Clockwise)

Preceding gene: 16127078

Following gene: 16127080

Centisome position: 76.52

GC content: 71.53

Gene sequence:

>1605_bases
ATGAACGTCACCTTCTCCAACCTCGACGCCCAACGCCAGATCGGCGGCAAGCTGATCATCGCCCTCGCCTGGCTGCTGAT
CCCGATCGTGCTGGGCGCGCGCCTGGCCGTGCAGGCGCCCATCCTGGGGCTCTCGATCGCCGCGGTGCTGGTCGCCACGG
GCGCGACCCTGGCCTGGAAGTTCGCCGGCGGGGGATCTGGCGGACGCGCCATGGTGGGGGTCGCGCTGATGGCGCAGGTC
TCGCTGCTGGTCGCGGCCCTGGGCGGTCACGCCTGGCAGGCCGACATGCACATGGCCTATTTCGCGGCCCTGGCCCTGCT
GGTCGTCTATTGCGACTGGATGGTGATCGCCGCCGCCGCCGCGACGGTGGCCGTGCATCACCTGGGCCTGTCCTATCTGG
CGCCCAGCCTGGTGTTTCCGGGCTCGGCCAATCTGGGGCGGGTCATCGTCCACGCGGTGATCCTGATCGTCGAGGCCGCC
GCCCTGATCGCCGTCGCCGCCAGCGTCAACAACATGTTCGCCATCGCCAATACGGCCCGGTCCAAGGCCGAGGACGCCGT
GGGCGAGGCGCGCGCGGCCAATGACGCGGCCGAGGACGCCCGCCGCTCGGAGGAAGAGACCCGCGCCCGCAACGCCGCCG
CCCGCGAGCGCGAGGAAGCCCAGCGCGACAACGCCATCGCCGCCCTCGGCCAGGGGCTGTCGCATCTGGCGCGGGGCGAC
CTGACCCTGCGCCTGACCGATCGCTTCGCCGAGGCCTATGAGCCGCTGCGCGCCGACTTCAACACCGCCGCCGGCAAGCT
GGCCGACGCGCTTTCGGTGATCGAGCAACGCGTCAGCGGCGTGCGCGCCGGCGCCGACCAGATCGCCGACGCCGCCGTCA
ACCTGTCGCGCCGCACCGAGCGTCAGGCCGCCAGCCTGGAAGAGACCGCCGCAGCGATGGACGAAATCACCGCCACCGTC
GGCCAGACCGCAACGGGCGCCAACAAGGCCGCCGACGTCGTCAGCCGCGCGCGCGAGGACGCCCGCCGCTCGGGCGAGGT
GGTCGAGCAGGCGGTGTCGGCCATGACCGGCATCGAGGAGTCCTCGCAGTCGATCAGCCAGATCATCAGCGTGATCGACG
AAATCGCCTTCCAGACCAACCTCCTGGCCCTGAACGCCGGTGTCGAGGCCGCCCGCGCGGGCGAGGCCGGCCGAGGCTTC
GCGGTCGTGGCGCAGGAGGTCCGCGCCCTGGCCCAGCGTTCGGCCGAGGCCGCCAAGGAGATCCGCGCCCTGATCTCCAA
CTCGACCCAGCAGGTCGAGACGGGCGTCAACCTGGTGGGCCGCACCGGCGAGGCGCTGGAGCGCATCGTCGCCCAGATCG
CCGAGATCGACGGCCTGGTCCGCACCATCGCCGCCTCGGCCCAGGAACAGGCCAGCGGCCTGGCCCAGATCAACGGCGCG
GTGAACCAGATGGATCAGGTGCTGCAGGAGAACGCCGGCATGGTCGAAGAGACCTCGGCCGCCACCCAGACCCTCAACAC
CGACGCCACCCAGCTGGCCGATCTGGTGCGCCAGTTCGACCTACCGCGAGGCCATATCGAGCAGTCCCAGCGGCGGGTCG
CCTAG

Upstream 100 bases:

>100_bases
CCACGCTGAACCAGCGCGCCCGGACCGCCGGCGCGTGGCTGTTACTGGATCCCGCCCTCGCCGGCGCGTGCGCGCGTCCG
GCTTCGGAGCCTGTATCGTC

Downstream 100 bases:

>100_bases
GACGCGGCGCGGCGCCCTTTCGCGCCGCGCCGTTGCAAGCTCAAGCTTGGCCCCCTTGCGTTACCGGAACCGGGCGCCTA
TCCTCCCAGCCCCCGGTTGT

Product: methyl-accepting chemotaxis protein McpI

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 534; Mature: 534

Protein sequence:

>534_residues
MNVTFSNLDAQRQIGGKLIIALAWLLIPIVLGARLAVQAPILGLSIAAVLVATGATLAWKFAGGGSGGRAMVGVALMAQV
SLLVAALGGHAWQADMHMAYFAALALLVVYCDWMVIAAAAATVAVHHLGLSYLAPSLVFPGSANLGRVIVHAVILIVEAA
ALIAVAASVNNMFAIANTARSKAEDAVGEARAANDAAEDARRSEEETRARNAAAREREEAQRDNAIAALGQGLSHLARGD
LTLRLTDRFAEAYEPLRADFNTAAGKLADALSVIEQRVSGVRAGADQIADAAVNLSRRTERQAASLEETAAAMDEITATV
GQTATGANKAADVVSRAREDARRSGEVVEQAVSAMTGIEESSQSISQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGF
AVVAQEVRALAQRSAEAAKEIRALISNSTQQVETGVNLVGRTGEALERIVAQIAEIDGLVRTIAASAQEQASGLAQINGA
VNQMDQVLQENAGMVEETSAATQTLNTDATQLADLVRQFDLPRGHIEQSQRRVA

Sequences:

>Translated_534_residues
MNVTFSNLDAQRQIGGKLIIALAWLLIPIVLGARLAVQAPILGLSIAAVLVATGATLAWKFAGGGSGGRAMVGVALMAQV
SLLVAALGGHAWQADMHMAYFAALALLVVYCDWMVIAAAAATVAVHHLGLSYLAPSLVFPGSANLGRVIVHAVILIVEAA
ALIAVAASVNNMFAIANTARSKAEDAVGEARAANDAAEDARRSEEETRARNAAAREREEAQRDNAIAALGQGLSHLARGD
LTLRLTDRFAEAYEPLRADFNTAAGKLADALSVIEQRVSGVRAGADQIADAAVNLSRRTERQAASLEETAAAMDEITATV
GQTATGANKAADVVSRAREDARRSGEVVEQAVSAMTGIEESSQSISQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGF
AVVAQEVRALAQRSAEAAKEIRALISNSTQQVETGVNLVGRTGEALERIVAQIAEIDGLVRTIAASAQEQASGLAQINGA
VNQMDQVLQENAGMVEETSAATQTLNTDATQLADLVRQFDLPRGHIEQSQRRVA
>Mature_534_residues
MNVTFSNLDAQRQIGGKLIIALAWLLIPIVLGARLAVQAPILGLSIAAVLVATGATLAWKFAGGGSGGRAMVGVALMAQV
SLLVAALGGHAWQADMHMAYFAALALLVVYCDWMVIAAAAATVAVHHLGLSYLAPSLVFPGSANLGRVIVHAVILIVEAA
ALIAVAASVNNMFAIANTARSKAEDAVGEARAANDAAEDARRSEEETRARNAAAREREEAQRDNAIAALGQGLSHLARGD
LTLRLTDRFAEAYEPLRADFNTAAGKLADALSVIEQRVSGVRAGADQIADAAVNLSRRTERQAASLEETAAAMDEITATV
GQTATGANKAADVVSRAREDARRSGEVVEQAVSAMTGIEESSQSISQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGF
AVVAQEVRALAQRSAEAAKEIRALISNSTQQVETGVNLVGRTGEALERIVAQIAEIDGLVRTIAASAQEQASGLAQINGA
VNQMDQVLQENAGMVEETSAATQTLNTDATQLADLVRQFDLPRGHIEQSQRRVA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI2367378, Length=270, Percent_Identity=46.6666666666667, Blast_Score=202, Evalue=3e-53,
Organism=Escherichia coli, GI1788195, Length=229, Percent_Identity=49.3449781659389, Blast_Score=197, Evalue=1e-51,
Organism=Escherichia coli, GI1787690, Length=304, Percent_Identity=42.1052631578947, Blast_Score=197, Evalue=2e-51,
Organism=Escherichia coli, GI1788194, Length=256, Percent_Identity=47.265625, Blast_Score=192, Evalue=3e-50,
Organism=Escherichia coli, GI1789453, Length=243, Percent_Identity=40.3292181069959, Blast_Score=165, Evalue=5e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 55639; Mature: 55639

Theoretical pI: Translated: 4.83; Mature: 4.83

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNVTFSNLDAQRQIGGKLIIALAWLLIPIVLGARLAVQAPILGLSIAAVLVATGATLAWK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHEEE
FAGGGSGGRAMVGVALMAQVSLLVAALGGHAWQADMHMAYFAALALLVVYCDWMVIAAAA
ECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATVAVHHLGLSYLAPSLVFPGSANLGRVIVHAVILIVEAAALIAVAASVNNMFAIANTAR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKAEDAVGEARAANDAAEDARRSEEETRARNAAAREREEAQRDNAIAALGQGLSHLARGD
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LTLRLTDRFAEAYEPLRADFNTAAGKLADALSVIEQRVSGVRAGADQIADAAVNLSRRTE
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RQAASLEETAAAMDEITATVGQTATGANKAADVVSRAREDARRSGEVVEQAVSAMTGIEE
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
SSQSISQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVRALAQRSAEAAKE
HHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IRALISNSTQQVETGVNLVGRTGEALERIVAQIAEIDGLVRTIAASAQEQASGLAQINGA
HHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNQMDQVLQENAGMVEETSAATQTLNTDATQLADLVRQFDLPRGHIEQSQRRVA
HHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCC
>Mature Secondary Structure
MNVTFSNLDAQRQIGGKLIIALAWLLIPIVLGARLAVQAPILGLSIAAVLVATGATLAWK
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHEEE
FAGGGSGGRAMVGVALMAQVSLLVAALGGHAWQADMHMAYFAALALLVVYCDWMVIAAAA
ECCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ATVAVHHLGLSYLAPSLVFPGSANLGRVIVHAVILIVEAAALIAVAASVNNMFAIANTAR
HHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
SKAEDAVGEARAANDAAEDARRSEEETRARNAAAREREEAQRDNAIAALGQGLSHLARGD
HHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LTLRLTDRFAEAYEPLRADFNTAAGKLADALSVIEQRVSGVRAGADQIADAAVNLSRRTE
CEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHH
RQAASLEETAAAMDEITATVGQTATGANKAADVVSRAREDARRSGEVVEQAVSAMTGIEE
HHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHH
SSQSISQIISVIDEIAFQTNLLALNAGVEAARAGEAGRGFAVVAQEVRALAQRSAEAAKE
HHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHH
IRALISNSTQQVETGVNLVGRTGEALERIVAQIAEIDGLVRTIAASAQEQASGLAQINGA
HHHHHHCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VNQMDQVLQENAGMVEETSAATQTLNTDATQLADLVRQFDLPRGHIEQSQRRVA
HHHHHHHHHHCCCCCHHHHHHHHHCCCCHHHHHHHHHHHCCCCHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]