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The map label for this gene is fecR [H]

Identifier: 16126941

GI number: 16126941

Start: 2920715

End: 2921788

Strand: Direct

Name: fecR [H]

Synonym: CC_2708

Alternate gene names: 16126941

Gene position: 2920715-2921788 (Clockwise)

Preceding gene: 16126940

Following gene: 16126942

Centisome position: 72.71

GC content: 70.02

Gene sequence:

>1074_bases
ATGATCGATGACCAAGCCAAGGCTGCAAACGCTCAGCCCGGCGGGGCGGAACCCTCCGGTGCGCGGGACAGGCGCGCGCG
CGACGAGGCGGCCGCCTGGTACGGCAAGATGAGCGGCCAGCGGGTCAGCAACGCCGATTTGGCGGCCTTCTTCGCCTGGC
GCGAGAACAGCCTCAATGACGCGGCCTACACCCGGATCGAGGCCTTAACGACAAGCGTGCGCGCCTTGGCGGACGACCCC
AGACTTCAGGCGATCGCCGAGACGGCGGCGCGTCGACCGCGCGGCGTCGTTGCGCGTCTACGCAGCCTTGGCCAAGGCGC
AGGGCTCAGGACGGCCGGCGTCGGCGCGGCTCTGGTCGCGGCCATGGTGATCGGTGCGGTGCTGCTTGGCCAAGTCGGTC
AGCAGACCTATCGCACGCAGATCGGCGAGCGGCGGGCCGTTAGCCTGGACGACGGCTCGACGATCGAGCTCAACACCAAC
AGCCAGGTGCGGGTGCGTCTGTCCAAGACGCAGCGCAGCCTGATCCTCGACAGGGGACAGGCGATGTTCATCGTGGCCCA
TGACGCAGCGCGTCCGTTCGTCGTCACGGCCGGAGACACTTCGGTGCGGGCCATAGGCACCCGGTTCGAGGTCTATCGGG
CCGCCGGCGCGGTGCGGGTGACCTTGGCGGAGGGCCGCGTCCAGGTCAGCAAGGCTGGCCGGCGGAACGATGGCGGCGGA
CAAGGCGGCGAGCGTTCCACACCGGTGATCCTGAACGCCGGACAGCGGGTCGACATGGCTCCTGCCGCACCGGCCAGCCC
GGTGGCTGTCGACGTCGCGGCGGTGACCGGGTGGACTCGCGGGCGCCTGACCTTCAAGGATGCGTCCCTGGCCGAGGCCG
TGGCGGAGGTCAATCGCTATAGCCGTCGCCAAGTGGTGCTGGGTCCCGGGACGCCGGCCGATCAGCGGGTCAATGGTGAG
TTCGACGCCGGCGATACCGAGACCTTCGCCCGCGGCATGGCCGTGCTGCTGGACTTGAAGACCGTCGCGCGCCCGGACGG
GGGCATCGAACTGGCCGCCTCGCCCGCCGTTTGA

Upstream 100 bases:

>100_bases
CGCGCAACTGCGCGGCATCTCCGTCAAGGCGGTGGAGAAGCGAATGACCCAGGCTATCGCGCGATGCGCCGACATGATCC
GGGGCTAGGCGGATCACGCC

Downstream 100 bases:

>100_bases
CGGCAAAAATCTTTCGTCGCCCGGTAGGGTGAGACGGCTTCCCAGGCGTCTCAGCCCTGCCGCGCCCCGGCAAGAGACCG
CCACAGTGGCGGCCCCGTGC

Product: transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 357; Mature: 357

Protein sequence:

>357_residues
MIDDQAKAANAQPGGAEPSGARDRRARDEAAAWYGKMSGQRVSNADLAAFFAWRENSLNDAAYTRIEALTTSVRALADDP
RLQAIAETAARRPRGVVARLRSLGQGAGLRTAGVGAALVAAMVIGAVLLGQVGQQTYRTQIGERRAVSLDDGSTIELNTN
SQVRVRLSKTQRSLILDRGQAMFIVAHDAARPFVVTAGDTSVRAIGTRFEVYRAAGAVRVTLAEGRVQVSKAGRRNDGGG
QGGERSTPVILNAGQRVDMAPAAPASPVAVDVAAVTGWTRGRLTFKDASLAEAVAEVNRYSRRQVVLGPGTPADQRVNGE
FDAGDTETFARGMAVLLDLKTVARPDGGIELAASPAV

Sequences:

>Translated_357_residues
MIDDQAKAANAQPGGAEPSGARDRRARDEAAAWYGKMSGQRVSNADLAAFFAWRENSLNDAAYTRIEALTTSVRALADDP
RLQAIAETAARRPRGVVARLRSLGQGAGLRTAGVGAALVAAMVIGAVLLGQVGQQTYRTQIGERRAVSLDDGSTIELNTN
SQVRVRLSKTQRSLILDRGQAMFIVAHDAARPFVVTAGDTSVRAIGTRFEVYRAAGAVRVTLAEGRVQVSKAGRRNDGGG
QGGERSTPVILNAGQRVDMAPAAPASPVAVDVAAVTGWTRGRLTFKDASLAEAVAEVNRYSRRQVVLGPGTPADQRVNGE
FDAGDTETFARGMAVLLDLKTVARPDGGIELAASPAV
>Mature_357_residues
MIDDQAKAANAQPGGAEPSGARDRRARDEAAAWYGKMSGQRVSNADLAAFFAWRENSLNDAAYTRIEALTTSVRALADDP
RLQAIAETAARRPRGVVARLRSLGQGAGLRTAGVGAALVAAMVIGAVLLGQVGQQTYRTQIGERRAVSLDDGSTIELNTN
SQVRVRLSKTQRSLILDRGQAMFIVAHDAARPFVVTAGDTSVRAIGTRFEVYRAAGAVRVTLAEGRVQVSKAGRRNDGGG
QGGERSTPVILNAGQRVDMAPAAPASPVAVDVAAVTGWTRGRLTFKDASLAEAVAEVNRYSRRQVVLGPGTPADQRVNGE
FDAGDTETFARGMAVLLDLKTVARPDGGIELAASPAV

Specific function: Regulation of iron dicitrate transport. In the absence of citrate fecR inactivates fecI. FecR is probably a sensor that recognizes iron dicitrate in the periplasm [H]

COG id: COG3712

COG function: function code PT; Fe2+-dicitrate sensor, membrane component

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

Organism=Escherichia coli, GI1790745, Length=322, Percent_Identity=26.0869565217391, Blast_Score=74, Evalue=2e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006860
- InterPro:   IPR012373 [H]

Pfam domain/function: PF04773 FecR [H]

EC number: NA

Molecular weight: Translated: 37486; Mature: 37486

Theoretical pI: Translated: 10.81; Mature: 10.81

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDDQAKAANAQPGGAEPSGARDRRARDEAAAWYGKMSGQRVSNADLAAFFAWRENSLND
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCH
AAYTRIEALTTSVRALADDPRLQAIAETAARRPRGVVARLRSLGQGAGLRTAGVGAALVA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
AMVIGAVLLGQVGQQTYRTQIGERRAVSLDDGSTIELNTNSQVRVRLSKTQRSLILDRGQ
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCEEEEEEEHHHHHHHHCCCC
AMFIVAHDAARPFVVTAGDTSVRAIGTRFEVYRAAGAVRVTLAEGRVQVSKAGRRNDGGG
EEEEEEECCCCCEEEECCCCCEEHHHHHHHHHHCCCEEEEEEECCEEEEECCCCCCCCCC
QGGERSTPVILNAGQRVDMAPAAPASPVAVDVAAVTGWTRGRLTFKDASLAEAVAEVNRY
CCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCHHHHHHHHHHHHH
SRRQVVLGPGTPADQRVNGEFDAGDTETFARGMAVLLDLKTVARPDGGIELAASPAV
CCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC
>Mature Secondary Structure
MIDDQAKAANAQPGGAEPSGARDRRARDEAAAWYGKMSGQRVSNADLAAFFAWRENSLND
CCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCCCCH
AAYTRIEALTTSVRALADDPRLQAIAETAARRPRGVVARLRSLGQGAGLRTAGVGAALVA
HHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCHHHHHHHHHH
AMVIGAVLLGQVGQQTYRTQIGERRAVSLDDGSTIELNTNSQVRVRLSKTQRSLILDRGQ
HHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCCEEEECCCCEEEEEEEHHHHHHHHCCCC
AMFIVAHDAARPFVVTAGDTSVRAIGTRFEVYRAAGAVRVTLAEGRVQVSKAGRRNDGGG
EEEEEEECCCCCEEEECCCCCEEHHHHHHHHHHCCCEEEEEEECCEEEEECCCCCCCCCC
QGGERSTPVILNAGQRVDMAPAAPASPVAVDVAAVTGWTRGRLTFKDASLAEAVAEVNRY
CCCCCCCCEEEECCCCCCCCCCCCCCCCEEEEEECCCCCCCEEEECCHHHHHHHHHHHHH
SRRQVVLGPGTPADQRVNGEFDAGDTETFARGMAVLLDLKTVARPDGGIELAASPAV
CCCEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2254251; 7610040; 9278503 [H]