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The map label for this gene is hfaC

Identifier: 16126866

GI number: 16126866

Start: 2847175

End: 2849001

Strand: Direct

Name: hfaC

Synonym: CC_2631

Alternate gene names: 16126866

Gene position: 2847175-2849001 (Clockwise)

Preceding gene: 16126865

Following gene: 16126867

Centisome position: 70.88

GC content: 68.8

Gene sequence:

>1827_bases
ATGGCCTCTCCCGCCCGCGCGCCCGTACTCGCCCTCAAGGATGTCCGTCTCGCCGACGGCGCCAAACCCCTCTTCGATGG
GGTGGACCTGGCCCTGGAGCCGCGCGTGCGCGCCTGCCTCGTCGGTCGCAACGGCGCGGGCAAGTCGACCTTGCTGAAGA
TCCTGGCCGGCCAGGGCGTCGAGGCCGACAGCGGCGAACGCGCCGTCCAGCCCGGCGCCAAGGTCGTCTATGTCAGCCAG
GAGCCGGAGATCACCGGCGAGACCCTGCTGGACTATGCGACGGCGGGCGGCGCTCAGGACTACGAGGCCCAGGCCGCCCT
GGCCGATTTCGGCCTGGACCCCGACAAGAGCGCCAAGGGTCTGTCGGGCGGCGAGACCCGCCGCGCCGCGCTGGCCCGCG
CCTTCGCCGAGCAGCCCGACGTGCTGCTGCTGGACGAGCCGACCAACCACCTCGACATCTTCGCCATCCAGACGCTGGAA
GACGAGCTGGCCGCCTCCAAGTGCGCGGCCCTGATCGTCAGCCACGACCGCGCCTTCCTCAACCGCGTGACCGAGCGCTG
CTTCTGGCTGGAGCACCGCAAGATCCGCCGCCTGGACAAGGGCTTCTCGGAGTTCGAGGCCTGGGCGGAGTCGATCATGG
CCGCCGACGCCGAAGAGGCGCGGCGCCTGGACAAGGTGCTGGAGCGCGAGAACGCTTGGCTGGCCCGAGGCGTCCAGGGC
CGCCGCGCCCGCAACGAGGGCCGCCGCCGCGCGCTTCTGGCCCTGCGCGCCGAGAAGAAGGACCGCCAGAGCGAACTGCG
CGGGACCATGACCATGGCCGTGGAGTCCGCGGGGACCTCCGGCAAGCGCGTGGTCGAGGCCAAAGGCGTCACCAAGCGCT
TTGGCGAGCGGACGATCGTCGAGAACTTCTCCACCCGCATCCTGCGCGGTGATCGCGTGGCTCTGGTCGGCCCCAACGGC
GCGGGCAAGACCACCTTGGTCAAGCTGCTGCTGGGCGAGCTGGAGCGTGACGCGGGCACGGTGCAGCTGGGGACCAATCT
GGAGGTCTCCTATATCGACCAGGCCCGCATGGCCCTCTCGGACAAGATCACCGTCTGGGACTTCCTGACCCCCGGCGGCG
GGGACTCGATCATCGTGCGCGGCCACCCCAAGCATGTCGCCGGCTACGCCAAGGAGTTCCTGTTCACCGACGCCCAGCTG
CGACAGCCCGTCACTAGCCTGTCGGGCGGCGAGCGCAACCGCCTGCTGCTGGCGAGAGCCTTGGCCAATCCCACCAACCT
AATGGTGCTGGACGAGCCGACCAACGATCTGGACATGGACACGCTGGATCTCCTGGAAGACCTGCTGGCCGATTTCGACG
GCACGCTGATCCTGGTCAGCCACGACCGCGACTTCATCGACCGGTTGGCCAGCTCGACCATCGCTCTGGACGGCAAGGGC
GGTGTCGTGGAGACACCCGGCGGCTGGACCGACCTGATGGACCAGAACCCGGACTTCTTCAAAGCCTCGAAGGGCGGAAC
CGCCTTCGCGCCCGTCTCCAAGGCCGCGACCAAGCCCGCCCCCGCCGCCCCGGCCGCTCCGAAGAAGAGCGCCAAGCTCT
CCTACAAGGACCAGCGCCGCCTGGAGGAATGCGAGGCCCTGATCGCCAAGAGCCCGGCGATCATCGCCAAGCTTGAGGAA
GCCCTGGCCGATCCGAACCTCTACACCCGCGATCCCGCCACCTTCGACAAGACGATGAAGGCCCTCGACAAGGCGCGCGC
CGACCTGGAGCAGGCCGAGATGGAATGGCTGGAGCTTGAGGAGAAGAAAGAGAATCTGGCGGGCTGA

Upstream 100 bases:

>100_bases
GCGCTGCGATCGAGAATTTGGCGTTCCTTCGGTCGCGGGCCTGCTATAGGCCCTCTCCTCCCGCGACATTCCGCAGCCTC
GACCCAGTATCCAGACGATC

Downstream 100 bases:

>100_bases
CCGGACGGCGCACGGCCAAGCTCAGCGCCAAGCTGTGCGACGAAATGACACATCCGGCGATTGCTAGGCCCCTGGGGCGC
GTCCGGTCTTAATGTGGGCG

Product: ABC transporter ATP-binding protein

Products: NA

Alternate protein names: Protein HfaC

Number of amino acids: Translated: 608; Mature: 607

Protein sequence:

>608_residues
MASPARAPVLALKDVRLADGAKPLFDGVDLALEPRVRACLVGRNGAGKSTLLKILAGQGVEADSGERAVQPGAKVVYVSQ
EPEITGETLLDYATAGGAQDYEAQAALADFGLDPDKSAKGLSGGETRRAALARAFAEQPDVLLLDEPTNHLDIFAIQTLE
DELAASKCAALIVSHDRAFLNRVTERCFWLEHRKIRRLDKGFSEFEAWAESIMAADAEEARRLDKVLERENAWLARGVQG
RRARNEGRRRALLALRAEKKDRQSELRGTMTMAVESAGTSGKRVVEAKGVTKRFGERTIVENFSTRILRGDRVALVGPNG
AGKTTLVKLLLGELERDAGTVQLGTNLEVSYIDQARMALSDKITVWDFLTPGGGDSIIVRGHPKHVAGYAKEFLFTDAQL
RQPVTSLSGGERNRLLLARALANPTNLMVLDEPTNDLDMDTLDLLEDLLADFDGTLILVSHDRDFIDRLASSTIALDGKG
GVVETPGGWTDLMDQNPDFFKASKGGTAFAPVSKAATKPAPAAPAAPKKSAKLSYKDQRRLEECEALIAKSPAIIAKLEE
ALADPNLYTRDPATFDKTMKALDKARADLEQAEMEWLELEEKKENLAG

Sequences:

>Translated_608_residues
MASPARAPVLALKDVRLADGAKPLFDGVDLALEPRVRACLVGRNGAGKSTLLKILAGQGVEADSGERAVQPGAKVVYVSQ
EPEITGETLLDYATAGGAQDYEAQAALADFGLDPDKSAKGLSGGETRRAALARAFAEQPDVLLLDEPTNHLDIFAIQTLE
DELAASKCAALIVSHDRAFLNRVTERCFWLEHRKIRRLDKGFSEFEAWAESIMAADAEEARRLDKVLERENAWLARGVQG
RRARNEGRRRALLALRAEKKDRQSELRGTMTMAVESAGTSGKRVVEAKGVTKRFGERTIVENFSTRILRGDRVALVGPNG
AGKTTLVKLLLGELERDAGTVQLGTNLEVSYIDQARMALSDKITVWDFLTPGGGDSIIVRGHPKHVAGYAKEFLFTDAQL
RQPVTSLSGGERNRLLLARALANPTNLMVLDEPTNDLDMDTLDLLEDLLADFDGTLILVSHDRDFIDRLASSTIALDGKG
GVVETPGGWTDLMDQNPDFFKASKGGTAFAPVSKAATKPAPAAPAAPKKSAKLSYKDQRRLEECEALIAKSPAIIAKLEE
ALADPNLYTRDPATFDKTMKALDKARADLEQAEMEWLELEEKKENLAG
>Mature_607_residues
ASPARAPVLALKDVRLADGAKPLFDGVDLALEPRVRACLVGRNGAGKSTLLKILAGQGVEADSGERAVQPGAKVVYVSQE
PEITGETLLDYATAGGAQDYEAQAALADFGLDPDKSAKGLSGGETRRAALARAFAEQPDVLLLDEPTNHLDIFAIQTLED
ELAASKCAALIVSHDRAFLNRVTERCFWLEHRKIRRLDKGFSEFEAWAESIMAADAEEARRLDKVLERENAWLARGVQGR
RARNEGRRRALLALRAEKKDRQSELRGTMTMAVESAGTSGKRVVEAKGVTKRFGERTIVENFSTRILRGDRVALVGPNGA
GKTTLVKLLLGELERDAGTVQLGTNLEVSYIDQARMALSDKITVWDFLTPGGGDSIIVRGHPKHVAGYAKEFLFTDAQLR
QPVTSLSGGERNRLLLARALANPTNLMVLDEPTNDLDMDTLDLLEDLLADFDGTLILVSHDRDFIDRLASSTIALDGKGG
VVETPGGWTDLMDQNPDFFKASKGGTAFAPVSKAATKPAPAAPAAPKKSAKLSYKDQRRLEECEALIAKSPAIIAKLEEA
LADPNLYTRDPATFDKTMKALDKARADLEQAEMEWLELEEKKENLAG

Specific function: Involved in attachment of the holdfast to the cell. The holdfast is a structure that allows the bacteria to firmly adhere to surfaces

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains

Homologues:

Organism=Homo sapiens, GI148612853, Length=548, Percent_Identity=29.5620437956204, Blast_Score=159, Evalue=7e-39,
Organism=Homo sapiens, GI27881506, Length=530, Percent_Identity=27.3584905660377, Blast_Score=136, Evalue=5e-32,
Organism=Homo sapiens, GI10947137, Length=530, Percent_Identity=27.3584905660377, Blast_Score=136, Evalue=6e-32,
Organism=Homo sapiens, GI10947135, Length=512, Percent_Identity=25.9765625, Blast_Score=126, Evalue=5e-29,
Organism=Homo sapiens, GI69354671, Length=512, Percent_Identity=25.9765625, Blast_Score=126, Evalue=6e-29,
Organism=Escherichia coli, GI1787182, Length=622, Percent_Identity=37.620578778135, Blast_Score=360, Evalue=1e-100,
Organism=Escherichia coli, GI2367384, Length=547, Percent_Identity=31.6270566727605, Blast_Score=241, Evalue=7e-65,
Organism=Escherichia coli, GI1787041, Length=537, Percent_Identity=29.4227188081937, Blast_Score=199, Evalue=5e-52,
Organism=Escherichia coli, GI1789751, Length=653, Percent_Identity=25.7274119448698, Blast_Score=192, Evalue=4e-50,
Organism=Escherichia coli, GI1788165, Length=224, Percent_Identity=30.8035714285714, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI48994943, Length=504, Percent_Identity=24.6031746031746, Blast_Score=91, Evalue=3e-19,
Organism=Escherichia coli, GI87081782, Length=485, Percent_Identity=25.5670103092783, Blast_Score=84, Evalue=4e-17,
Organism=Escherichia coli, GI87081709, Length=244, Percent_Identity=30.327868852459, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1787029, Length=235, Percent_Identity=29.3617021276596, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788225, Length=225, Percent_Identity=29.7777777777778, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1786803, Length=210, Percent_Identity=32.3809523809524, Blast_Score=76, Evalue=7e-15,
Organism=Escherichia coli, GI1788761, Length=211, Percent_Identity=30.3317535545024, Blast_Score=72, Evalue=1e-13,
Organism=Escherichia coli, GI1787758, Length=195, Percent_Identity=29.7435897435897, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI87081791, Length=219, Percent_Identity=30.1369863013699, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1789891, Length=221, Percent_Identity=26.6968325791855, Blast_Score=69, Evalue=9e-13,
Organism=Escherichia coli, GI87081834, Length=224, Percent_Identity=27.6785714285714, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1787712, Length=197, Percent_Identity=29.9492385786802, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1787164, Length=178, Percent_Identity=30.8988764044944, Blast_Score=68, Evalue=2e-12,
Organism=Escherichia coli, GI1789672, Length=218, Percent_Identity=25.2293577981651, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1786563, Length=201, Percent_Identity=26.865671641791, Blast_Score=64, Evalue=4e-11,
Organism=Caenorhabditis elegans, GI17555318, Length=503, Percent_Identity=28.0318091451292, Blast_Score=146, Evalue=3e-35,
Organism=Caenorhabditis elegans, GI17553372, Length=526, Percent_Identity=28.1368821292776, Blast_Score=144, Evalue=2e-34,
Organism=Caenorhabditis elegans, GI17559834, Length=548, Percent_Identity=24.8175182481752, Blast_Score=142, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI71988343, Length=269, Percent_Identity=27.1375464684015, Blast_Score=73, Evalue=5e-13,
Organism=Saccharomyces cerevisiae, GI6321121, Length=418, Percent_Identity=29.6650717703349, Blast_Score=132, Evalue=2e-31,
Organism=Saccharomyces cerevisiae, GI6323278, Length=352, Percent_Identity=30.3977272727273, Blast_Score=129, Evalue=1e-30,
Organism=Saccharomyces cerevisiae, GI6320874, Length=528, Percent_Identity=25.5681818181818, Blast_Score=128, Evalue=3e-30,
Organism=Saccharomyces cerevisiae, GI6324314, Length=352, Percent_Identity=29.8295454545455, Blast_Score=125, Evalue=2e-29,
Organism=Saccharomyces cerevisiae, GI6325030, Length=350, Percent_Identity=30, Blast_Score=118, Evalue=3e-27,
Organism=Drosophila melanogaster, GI24642252, Length=533, Percent_Identity=30.0187617260788, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI18859989, Length=533, Percent_Identity=30.0187617260788, Blast_Score=176, Evalue=6e-44,
Organism=Drosophila melanogaster, GI24666836, Length=527, Percent_Identity=29.4117647058824, Blast_Score=161, Evalue=1e-39,
Organism=Drosophila melanogaster, GI24641342, Length=545, Percent_Identity=26.0550458715596, Blast_Score=140, Evalue=3e-33,
Organism=Drosophila melanogaster, GI221500365, Length=258, Percent_Identity=27.5193798449612, Blast_Score=71, Evalue=3e-12,
Organism=Drosophila melanogaster, GI116007184, Length=258, Percent_Identity=27.5193798449612, Blast_Score=71, Evalue=3e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): HFAC_CAUCR (Q45978)

Other databases:

- EMBL:   AE005673
- EMBL:   U01165
- PIR:   B87575
- RefSeq:   NP_421430.1
- ProteinModelPortal:   Q45978
- SMR:   Q45978
- GeneID:   943991
- GenomeReviews:   AE005673_GR
- KEGG:   ccr:CC_2631
- NMPDR:   fig|190650.1.peg.2610
- TIGR:   CC_2631
- HOGENOM:   HBG758042
- OMA:   WLALEML
- ProtClustDB:   CLSK891070
- GO:   GO:0009295
- GO:   GO:0006810
- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593
- InterPro:   IPR007406
- Gene3D:   G3DSA:3.40.1140.10
- SMART:   SM00382

Pfam domain/function: PF00005 ABC_tran

EC number: NA

Molecular weight: Translated: 66007; Mature: 65875

Theoretical pI: Translated: 5.24; Mature: 5.24

Prosite motif: PS00211 ABC_TRANSPORTER_1; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MASPARAPVLALKDVRLADGAKPLFDGVDLALEPRVRACLVGRNGAGKSTLLKILAGQGV
CCCCCCCCEEEEECCHHCCCCCHHHCCCCCEECCCEEEEEECCCCCCHHHHHHHHHCCCC
EADSGERAVQPGAKVVYVSQEPEITGETLLDYATAGGAQDYEAQAALADFGLDPDKSAKG
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCC
LSGGETRRAALARAFAEQPDVLLLDEPTNHLDIFAIQTLEDELAASKCAALIVSHDRAFL
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
NRVTERCFWLEHRKIRRLDKGFSEFEAWAESIMAADAEEARRLDKVLERENAWLARGVQG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCCC
RRARNEGRRRALLALRAEKKDRQSELRGTMTMAVESAGTSGKRVVEAKGVTKRFGERTIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCHHHHHCCHHHH
ENFSTRILRGDRVALVGPNGAGKTTLVKLLLGELERDAGTVQLGTNLEVSYIDQARMALS
HHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHH
DKITVWDFLTPGGGDSIIVRGHPKHVAGYAKEFLFTDAQLRQPVTSLSGGERNRLLLARA
CCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHCCHHHCCCCCCCCEEEEHH
LANPTNLMVLDEPTNDLDMDTLDLLEDLLADFDGTLILVSHDRDFIDRLASSTIALDGKG
HCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCEEEECCCC
GVVETPGGWTDLMDQNPDFFKASKGGTAFAPVSKAATKPAPAAPAAPKKSAKLSYKDQRR
CEEECCCCCHHHHCCCCCCEECCCCCCEECCCHHHCCCCCCCCCCCCCCCCCCCCHHHHH
LEECEALIAKSPAIIAKLEEALADPNLYTRDPATFDKTMKALDKARADLEQAEMEWLELE
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKKENLAG
HHHHCCCC
>Mature Secondary Structure 
ASPARAPVLALKDVRLADGAKPLFDGVDLALEPRVRACLVGRNGAGKSTLLKILAGQGV
CCCCCCCEEEEECCHHCCCCCHHHCCCCCEECCCEEEEEECCCCCCHHHHHHHHHCCCC
EADSGERAVQPGAKVVYVSQEPEITGETLLDYATAGGAQDYEAQAALADFGLDPDKSAKG
CCCCCCCCCCCCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHCCCCCCCCCCC
LSGGETRRAALARAFAEQPDVLLLDEPTNHLDIFAIQTLEDELAASKCAALIVSHDRAFL
CCCCHHHHHHHHHHHHCCCCEEEEECCCCCEEEEEEEHHHHHHHHHHHHHHHHHHHHHHH
NRVTERCFWLEHRKIRRLDKGFSEFEAWAESIMAADAEEARRLDKVLERENAWLARGVQG
HHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCHHHHCCCCC
RRARNEGRRRALLALRAEKKDRQSELRGTMTMAVESAGTSGKRVVEAKGVTKRFGERTIV
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCCCEEEECCCHHHHHCCHHHH
ENFSTRILRGDRVALVGPNGAGKTTLVKLLLGELERDAGTVQLGTNLEVSYIDQARMALS
HHHHHHHCCCCEEEEECCCCCCHHHHHHHHHHHHHCCCCEEEECCCCEEEHHHHHHHHHH
DKITVWDFLTPGGGDSIIVRGHPKHVAGYAKEFLFTDAQLRQPVTSLSGGERNRLLLARA
CCEEEEEEECCCCCCEEEEECCCHHHHHHHHHHHHCCHHHHCCHHHCCCCCCCCEEEEHH
LANPTNLMVLDEPTNDLDMDTLDLLEDLLADFDGTLILVSHDRDFIDRLASSTIALDGKG
HCCCCEEEEEECCCCCCCCHHHHHHHHHHHCCCCEEEEEECCHHHHHHHHCCEEEECCCC
GVVETPGGWTDLMDQNPDFFKASKGGTAFAPVSKAATKPAPAAPAAPKKSAKLSYKDQRR
CEEECCCCCHHHHCCCCCCEECCCCCCEECCCHHHCCCCCCCCCCCCCCCCCCCCHHHHH
LEECEALIAKSPAIIAKLEEALADPNLYTRDPATFDKTMKALDKARADLEQAEMEWLELE
HHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EKKENLAG
HHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Endonuclease; Excision [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647; 8150261