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The map label for this gene is yafC [C]

Identifier: 16126756

GI number: 16126756

Start: 2721678

End: 2722556

Strand: Direct

Name: yafC [C]

Synonym: CC_2517

Alternate gene names: 16126756

Gene position: 2721678-2722556 (Clockwise)

Preceding gene: 16126746

Following gene: 16126758

Centisome position: 67.75

GC content: 70.65

Gene sequence:

>879_bases
ATGAGCCGCTGGGACGGGATCGACGAATTCGTGGCGACAGCCGAGGCGGAGAGCTTCTCGCGCGCCGCGCGGCGGCTGGG
ACTGTCGACCTCCGGCGTCAGCCGCGCCGTCGCCACGCTGGAGGAGCGGTTACAGACCCGCCTGCTCTACCGCACCACGC
GCCGGGTCAGCCTGACTGACGCCGGGCGCGCGTTTCTGGCCAGGGCGCGACGGCTGATCGCCGAGCGCGACGAGGCCCTG
GCCTCGGTGGGCGAGGACGACGGCGATCCGCGCGGCCTGCTGCGGATGACCTGCTCGACGGCCTACGGCGAGCGCTTCGT
GGTTCCGGCGGTGAACCGCTTCATGCTGTCCCACCCCAAGCTGGCCCTTGAGATCGACCTCGACGACGCGGTGCGCGACA
TCGTCAGCGAAGGCTTCGACCTGGCGATCCGCTTTGGTCGACTGACCGACAGTCGCCTGATCGCCAAGCGCCTGGCCTCG
CGCACCCGGCGTCTGTGCGCGGCCCCGTCCTACCTGACCCGGGCGGGGGCGCCGCGCTCCATCGCCGACCTTGCGGCTCA
CACCTGCATCCTGGGGGCGGCGGACACCTGGCCGTTCCGCGACGGCGAACGCGAGATCGCCTTCAAGCCGCAAGGACGCT
GGCGCTGCAACAGCGGCCAGGCGGTGCTGGACGCCGCTCTCCTGGGGTTGGGCGTTTGCCAGTTGCCGAACTTCTATGTC
GATGCGGCCATCAGCGACGGCCGCCTGGTTCCGCTGCTCGAAGCCAACCGGCCGGAGGACGAGGGCGTATGGGCCGTCTA
TCCGCACCTGCGGCTTCTGCCGGCCAAGGTCCGACTGCTGGTCGAACACCTGGAAGAGGCCCTGAGCGGCCAGGGTTAG

Upstream 100 bases:

>100_bases
GTGTTTCGGCGATCTTGGTACGCCTGCGCGGCCTTGTCGATAATCCCGCACGACGCAAAACATTGTTGCAATAGCGGGAT
AGTCAGCGCACCTGTCCGAC

Downstream 100 bases:

>100_bases
ACCTTGACGATCGCGGGAAACCGGAACCGCCCGTCCAGCATCTCGGCCTTGGGCAGATAGGCGCGAAGATAAAGAGCGAA
GGGACCCGCCGCAGGCGCAG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: ORF2 [H]

Number of amino acids: Translated: 292; Mature: 291

Protein sequence:

>292_residues
MSRWDGIDEFVATAEAESFSRAARRLGLSTSGVSRAVATLEERLQTRLLYRTTRRVSLTDAGRAFLARARRLIAERDEAL
ASVGEDDGDPRGLLRMTCSTAYGERFVVPAVNRFMLSHPKLALEIDLDDAVRDIVSEGFDLAIRFGRLTDSRLIAKRLAS
RTRRLCAAPSYLTRAGAPRSIADLAAHTCILGAADTWPFRDGEREIAFKPQGRWRCNSGQAVLDAALLGLGVCQLPNFYV
DAAISDGRLVPLLEANRPEDEGVWAVYPHLRLLPAKVRLLVEHLEEALSGQG

Sequences:

>Translated_292_residues
MSRWDGIDEFVATAEAESFSRAARRLGLSTSGVSRAVATLEERLQTRLLYRTTRRVSLTDAGRAFLARARRLIAERDEAL
ASVGEDDGDPRGLLRMTCSTAYGERFVVPAVNRFMLSHPKLALEIDLDDAVRDIVSEGFDLAIRFGRLTDSRLIAKRLAS
RTRRLCAAPSYLTRAGAPRSIADLAAHTCILGAADTWPFRDGEREIAFKPQGRWRCNSGQAVLDAALLGLGVCQLPNFYV
DAAISDGRLVPLLEANRPEDEGVWAVYPHLRLLPAKVRLLVEHLEEALSGQG
>Mature_291_residues
SRWDGIDEFVATAEAESFSRAARRLGLSTSGVSRAVATLEERLQTRLLYRTTRRVSLTDAGRAFLARARRLIAERDEALA
SVGEDDGDPRGLLRMTCSTAYGERFVVPAVNRFMLSHPKLALEIDLDDAVRDIVSEGFDLAIRFGRLTDSRLIAKRLASR
TRRLCAAPSYLTRAGAPRSIADLAAHTCILGAADTWPFRDGEREIAFKPQGRWRCNSGQAVLDAALLGLGVCQLPNFYVD
AAISDGRLVPLLEANRPEDEGVWAVYPHLRLLPAKVRLLVEHLEEALSGQG

Specific function: Unknown

COG id: COG0583

COG function: function code K; Transcriptional regulator

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1786401, Length=285, Percent_Identity=34.0350877192982, Blast_Score=157, Evalue=7e-40,
Organism=Escherichia coli, GI145693193, Length=291, Percent_Identity=35.0515463917526, Blast_Score=156, Evalue=1e-39,
Organism=Escherichia coli, GI1787589, Length=283, Percent_Identity=32.8621908127208, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI87081978, Length=286, Percent_Identity=33.9160839160839, Blast_Score=150, Evalue=1e-37,
Organism=Escherichia coli, GI1789639, Length=295, Percent_Identity=30.5084745762712, Blast_Score=145, Evalue=3e-36,
Organism=Escherichia coli, GI1789440, Length=280, Percent_Identity=30.3571428571429, Blast_Score=138, Evalue=5e-34,
Organism=Escherichia coli, GI1787128, Length=283, Percent_Identity=30.0353356890459, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI145693105, Length=147, Percent_Identity=29.9319727891156, Blast_Score=81, Evalue=7e-17,
Organism=Escherichia coli, GI1789173, Length=245, Percent_Identity=26.9387755102041, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1790011, Length=260, Percent_Identity=25, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1787879, Length=270, Percent_Identity=26.2962962962963, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1790208, Length=140, Percent_Identity=29.2857142857143, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32171; Mature: 32040

Theoretical pI: Translated: 8.22; Mature: 8.22

Prosite motif: PS50931 HTH_LYSR ; PS00414 PROFILIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRWDGIDEFVATAEAESFSRAARRLGLSTSGVSRAVATLEERLQTRLLYRTTRRVSLTD
CCCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECH
AGRAFLARARRLIAERDEALASVGEDDGDPRGLLRMTCSTAYGERFVVPAVNRFMLSHPK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHCCCC
LALEIDLDDAVRDIVSEGFDLAIRFGRLTDSRLIAKRLASRTRRLCAAPSYLTRAGAPRS
EEEEECHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCH
IADLAAHTCILGAADTWPFRDGEREIAFKPQGRWRCNSGQAVLDAALLGLGVCQLPNFYV
HHHHHHHHHHEECCCCCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHCCCEEE
DAAISDGRLVPLLEANRPEDEGVWAVYPHLRLLPAKVRLLVEHLEEALSGQG
EEECCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
SRWDGIDEFVATAEAESFSRAARRLGLSTSGVSRAVATLEERLQTRLLYRTTRRVSLTD
CCCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHCEEEECH
AGRAFLARARRLIAERDEALASVGEDDGDPRGLLRMTCSTAYGERFVVPAVNRFMLSHPK
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCEEEHHHHHHHHHCCCC
LALEIDLDDAVRDIVSEGFDLAIRFGRLTDSRLIAKRLASRTRRLCAAPSYLTRAGAPRS
EEEEECHHHHHHHHHHCCCEEEEEECCCCHHHHHHHHHHHHHHHHHCCCHHHHHCCCCCH
IADLAAHTCILGAADTWPFRDGEREIAFKPQGRWRCNSGQAVLDAALLGLGVCQLPNFYV
HHHHHHHHHHEECCCCCCCCCCCCEEEECCCCCEEECCCHHHHHHHHHHHHHHHCCCEEE
DAAISDGRLVPLLEANRPEDEGVWAVYPHLRLLPAKVRLLVEHLEEALSGQG
EEECCCCCEEEEEECCCCCCCCEEEECCHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8635745; 7542800 [H]