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The map label for this gene is dinB [H]

Identifier: 16126705

GI number: 16126705

Start: 2672001

End: 2673257

Strand: Direct

Name: dinB [H]

Synonym: CC_2466

Alternate gene names: 16126705

Gene position: 2672001-2673257 (Clockwise)

Preceding gene: 16126704

Following gene: 16126706

Centisome position: 66.52

GC content: 69.13

Gene sequence:

>1257_bases
ATGAAGTCCCTGTGCCGCGACTGCGGGTGGACCGGCGCGACCAAGGTCGCGCGGTGTCCCGCCTGCGCCTCGCCGCGCAC
AGTGTTCCATGAAGAGCTGGGGACGCTCTCCATCGCCCACATGGACTGCGACGCCTTCTATGCCTCGGTGGAGAAGCGCG
ACGACCCGTCCCTGCGCGACCTGCCGGTGATCATCGGCGGCGGCAAGCGAGGGGTGGTCACCACGGCCTGCTACATCGCG
AGGATGAGCGGCGCCAAGTCGGCGATGCCGATGTTCAAGGCGCTGAAGCTGTGCCCCGACGCCGTGGTCATCAAGCCCAA
CTTCGCCAAATACAAGGAAGAGAGCCGGCGCATCCATGAGAAGCTCGACAGGCTCACCCCGCTGATCCAGCCGCTGAGCC
TGGATGAGGCCTGGATCGACCTGACGGGCACCGAGCGCCTGCATGGCGCAACCCCCGCCCAGATGCTGGCCAGACTGCAG
GCCGAGATCGAGCGCGATATCGGCCTGACCGTTTCGGTGGGCCTGGCCCCCAACAAGTTCCTGGCCAAGATCGCCTCGGA
GCTGGACAAGCCGCGCGGCTTCTCGGCCATCGGCGCGGCCGAGGCGCAGAGCTTTCTCGCCAACAAGCCGGTCAACATCC
TGCCGGGCGTGGGACCGGCCACCGTCGCCTCCCTGGCCGAGATCGGCCTGCGCACCGTGGGCGACATCGCCGCCGCTGAT
CTGAAGCTGCTGGCCAATCGCCTGGGCTCGGGCGGCATGCGGCTGCACCGGCTGGCCCACGGCCAGGACAGCCGCATCGT
CGACCCCGACCAGGCCCGCAAGACGATCAGCGCCGAGACCACCTTCAACGACGACCTGCACAAGCGCGAGGACCTGGAGG
ACGAACTCTGGCCGCTCTGCGAAAAGGTCGCCAAGCAGGCCCGCCAGGAAGGCGTCGCCGGCCGCGTGGCGACGTTGAAG
CTGCGCACCCCCGACTTCAAGATCCATACCCGCCGCCGCACCCTGGCGGTGCCGACCCAGACAGCTCGCACCCTGTTCCA
GGTGGCCCGCGAGCTCCTGTCCGCCGAACCGCGCGGTCTTGCCTACCGCCTGATCGGCGCGGGCCTGACCGAGTTCGTCG
ACGCCGACACCGCGGGCGCTGACATGTTCGCCGACGAAGAGCGCCGGGCCCTGAAGAGCGAAACCGCCATCGACGCCCTG
CGCGGCAAGTTCGGCGCCGCTGCGGTGGTCACCGGTCGCGCGCTCAAGGGGCGGTGA

Upstream 100 bases:

>100_bases
CCGACATCTTCGAGACCCCGGTGCGCAAGGCCGTGCACGGCGACAGCTCGGGCGTGCGCGGCGCCGTCTGGCTCTGGCCG
CCGGAGGTCTAGCCGCCACC

Downstream 100 bases:

>100_bases
CGTCCAGCCTTGCACGAGGCGACCTTGAGCCCCATTTCGACGCTTCACCCTCGGAACCGTTCGCGCGCGGCCTTCGCTCT
CCCAAACGTGAAGCCGAAAA

Product: DNA polymerase IV

Products: NA

Alternate protein names: Pol IV [H]

Number of amino acids: Translated: 418; Mature: 418

Protein sequence:

>418_residues
MKSLCRDCGWTGATKVARCPACASPRTVFHEELGTLSIAHMDCDAFYASVEKRDDPSLRDLPVIIGGGKRGVVTTACYIA
RMSGAKSAMPMFKALKLCPDAVVIKPNFAKYKEESRRIHEKLDRLTPLIQPLSLDEAWIDLTGTERLHGATPAQMLARLQ
AEIERDIGLTVSVGLAPNKFLAKIASELDKPRGFSAIGAAEAQSFLANKPVNILPGVGPATVASLAEIGLRTVGDIAAAD
LKLLANRLGSGGMRLHRLAHGQDSRIVDPDQARKTISAETTFNDDLHKREDLEDELWPLCEKVAKQARQEGVAGRVATLK
LRTPDFKIHTRRRTLAVPTQTARTLFQVARELLSAEPRGLAYRLIGAGLTEFVDADTAGADMFADEERRALKSETAIDAL
RGKFGAAAVVTGRALKGR

Sequences:

>Translated_418_residues
MKSLCRDCGWTGATKVARCPACASPRTVFHEELGTLSIAHMDCDAFYASVEKRDDPSLRDLPVIIGGGKRGVVTTACYIA
RMSGAKSAMPMFKALKLCPDAVVIKPNFAKYKEESRRIHEKLDRLTPLIQPLSLDEAWIDLTGTERLHGATPAQMLARLQ
AEIERDIGLTVSVGLAPNKFLAKIASELDKPRGFSAIGAAEAQSFLANKPVNILPGVGPATVASLAEIGLRTVGDIAAAD
LKLLANRLGSGGMRLHRLAHGQDSRIVDPDQARKTISAETTFNDDLHKREDLEDELWPLCEKVAKQARQEGVAGRVATLK
LRTPDFKIHTRRRTLAVPTQTARTLFQVARELLSAEPRGLAYRLIGAGLTEFVDADTAGADMFADEERRALKSETAIDAL
RGKFGAAAVVTGRALKGR
>Mature_418_residues
MKSLCRDCGWTGATKVARCPACASPRTVFHEELGTLSIAHMDCDAFYASVEKRDDPSLRDLPVIIGGGKRGVVTTACYIA
RMSGAKSAMPMFKALKLCPDAVVIKPNFAKYKEESRRIHEKLDRLTPLIQPLSLDEAWIDLTGTERLHGATPAQMLARLQ
AEIERDIGLTVSVGLAPNKFLAKIASELDKPRGFSAIGAAEAQSFLANKPVNILPGVGPATVASLAEIGLRTVGDIAAAD
LKLLANRLGSGGMRLHRLAHGQDSRIVDPDQARKTISAETTFNDDLHKREDLEDELWPLCEKVAKQARQEGVAGRVATLK
LRTPDFKIHTRRRTLAVPTQTARTLFQVARELLSAEPRGLAYRLIGAGLTEFVDADTAGADMFADEERRALKSETAIDAL
RGKFGAAAVVTGRALKGR

Specific function: Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by polIV. Exhibits

COG id: COG0389

COG function: function code L; Nucleotidyltransferase/DNA polymerase involved in DNA repair

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 umuC domain [H]

Homologues:

Organism=Homo sapiens, GI84043967, Length=351, Percent_Identity=26.4957264957265, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI7706681, Length=352, Percent_Identity=26.4204545454545, Blast_Score=118, Evalue=1e-26,
Organism=Homo sapiens, GI154350220, Length=345, Percent_Identity=26.3768115942029, Blast_Score=110, Evalue=2e-24,
Organism=Homo sapiens, GI7705344, Length=235, Percent_Identity=30.2127659574468, Blast_Score=100, Evalue=3e-21,
Organism=Escherichia coli, GI1786425, Length=339, Percent_Identity=38.9380530973451, Blast_Score=219, Evalue=4e-58,
Organism=Escherichia coli, GI1787432, Length=387, Percent_Identity=25.5813953488372, Blast_Score=97, Evalue=2e-21,
Organism=Caenorhabditis elegans, GI193205700, Length=394, Percent_Identity=29.4416243654822, Blast_Score=132, Evalue=3e-31,
Organism=Caenorhabditis elegans, GI193205702, Length=370, Percent_Identity=27.5675675675676, Blast_Score=94, Evalue=1e-19,
Organism=Caenorhabditis elegans, GI17537959, Length=392, Percent_Identity=24.4897959183673, Blast_Score=83, Evalue=3e-16,
Organism=Saccharomyces cerevisiae, GI6324921, Length=277, Percent_Identity=27.7978339350181, Blast_Score=85, Evalue=2e-17,
Organism=Drosophila melanogaster, GI21355641, Length=312, Percent_Identity=27.2435897435897, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI24644984, Length=312, Percent_Identity=27.2435897435897, Blast_Score=120, Evalue=2e-27,
Organism=Drosophila melanogaster, GI19923006, Length=335, Percent_Identity=26.865671641791, Blast_Score=112, Evalue=6e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017962
- InterPro:   IPR017961
- InterPro:   IPR001126
- InterPro:   IPR017963
- InterPro:   IPR022880 [H]

Pfam domain/function: PF00817 IMS [H]

EC number: =2.7.7.7 [H]

Molecular weight: Translated: 45267; Mature: 45267

Theoretical pI: Translated: 9.29; Mature: 9.29

Prosite motif: PS50173 UMUC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSLCRDCGWTGATKVARCPACASPRTVFHEELGTLSIAHMDCDAFYASVEKRDDPSLRD
CCHHHHHCCCCCCCHHHCCCCCCCCHHHHHHHHCCEEEEEECHHHHHHHHHCCCCCCCCC
LPVIIGGGKRGVVTTACYIARMSGAKSAMPMFKALKLCPDAVVIKPNFAKYKEESRRIHE
CCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHH
KLDRLTPLIQPLSLDEAWIDLTGTERLHGATPAQMLARLQAEIERDIGLTVSVGLAPNKF
HHHHHHHHHCCCCCCCCEEECCCCCHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHH
LAKIASELDKPRGFSAIGAAEAQSFLANKPVNILPGVGPATVASLAEIGLRTVGDIAAAD
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LKLLANRLGSGGMRLHRLAHGQDSRIVDPDQARKTISAETTFNDDLHKREDLEDELWPLC
HHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHH
EKVAKQARQEGVAGRVATLKLRTPDFKIHTRRRTLAVPTQTARTLFQVARELLSAEPRGL
HHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCEEECCHHHHHHHHHHHHHHHCCCCCCH
AYRLIGAGLTEFVDADTAGADMFADEERRALKSETAIDALRGKFGAAAVVTGRALKGR
HHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCC
>Mature Secondary Structure
MKSLCRDCGWTGATKVARCPACASPRTVFHEELGTLSIAHMDCDAFYASVEKRDDPSLRD
CCHHHHHCCCCCCCHHHCCCCCCCCHHHHHHHHCCEEEEEECHHHHHHHHHCCCCCCCCC
LPVIIGGGKRGVVTTACYIARMSGAKSAMPMFKALKLCPDAVVIKPNFAKYKEESRRIHE
CCEEEECCCCCHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCEEECCCHHHHHHHHHHHHH
KLDRLTPLIQPLSLDEAWIDLTGTERLHGATPAQMLARLQAEIERDIGLTVSVGLAPNKF
HHHHHHHHHCCCCCCCCEEECCCCCHHCCCCHHHHHHHHHHHHHHCCCCEEEECCCCHHH
LAKIASELDKPRGFSAIGAAEAQSFLANKPVNILPGVGPATVASLAEIGLRTVGDIAAAD
HHHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LKLLANRLGSGGMRLHRLAHGQDSRIVDPDQARKTISAETTFNDDLHKREDLEDELWPLC
HHHHHHHHCCCCHHHHHHHCCCCCCCCCHHHHHHHCCCCCCCCCHHHHHHCCHHHHHHHH
EKVAKQARQEGVAGRVATLKLRTPDFKIHTRRRTLAVPTQTARTLFQVARELLSAEPRGL
HHHHHHHHHCCCCCCEEEEEEECCCCEEEECCCEEECCHHHHHHHHHHHHHHHCCCCCCH
AYRLIGAGLTEFVDADTAGADMFADEERRALKSETAIDALRGKFGAAAVVTGRALKGR
HHHHHHCCHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCEEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11259647 [H]