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The map label for this gene is ccpA [H]

Identifier: 16126555

GI number: 16126555

Start: 2517530

End: 2518582

Strand: Direct

Name: ccpA [H]

Synonym: CC_2316

Alternate gene names: 16126555

Gene position: 2517530-2518582 (Clockwise)

Preceding gene: 16126551

Following gene: 16126557

Centisome position: 62.67

GC content: 67.71

Gene sequence:

>1053_bases
ATGAGTTCGGTGACGATCTACGACGTCGCCGCGAAGGCGGGCGTCTCGATCAAGACTGTTTCGCGCGTGATGAACAACGA
GCCGAACGTCCGGCCCGTCATGCGTGAACGCGTGCTCGCCGCCGCCGGCGAGCTGGGATACAGCCCCAATCTCTCGGCGC
GCAGCCTTGCCGGGTCCCGATCCTTTGTCATCGCCGTCTTTGTCGACGCTGCGCTGACGATCGACCACTGGCAGAGCGAA
CGCGGCGCCGACTATCTCAGCCGTATTCAGCTGGGCGCCACCCTGGTCTGTCGTGACGCGGGCTATCACCTGTTGATCGA
ACTGATCGACCACGAGGGGCCTCAGGTCCGTCAGGAGGTCGCCGCGTTGCTGGCCGCCCTGAAGCCAGACGGTGTGATCC
TCACCCCGCCCTCCTCCGACAACGCCGTGGTGCTGGAGCTCCTCGACCGGGCGGGCACGCCCTATGTCCGCGTCGGCCCG
GAACGGGCGGAGGGTCTGGGTCCGCGCGTCCATATGGATGACGTCGCCGCCGCCCGCGAGATGACCGATCACCTGATCGG
CCTGGGCCATAAACGCATCGGCTTCATCGTCGGCGAACCGCGCTATGGCGCCAGCCAGGCGCGGCGCGACGGCTATCTGG
AGGCGATGCGCGCGAAGGGCCTTTCCGTTCCCGAATTCTGGGTCAGGCAAGGCGACTTCACGTTCCAGTCCGGCCTGGAA
CAGGCGAAGGCGCTGCTGGCGCTGCCAGAGCGCCCCACCGCCATCTTCGCCAGCAATGACGATATGGCGCTGGGCGCCAT
CGCTGCGATCGCCGACGCGGGCCTGATGACGCCAGGCGATGTCTCAGTCGCCGGCTTCGACGACAGTCCCAGCTCCCGGT
TCAGCCGACCTCAGCTCACCACCGTGCGCCAGCCCGTCGCCGAGATGTCTTCGGTCGCGGCGAAGCTGCTGATCGAACGC
TCGCGGGGTGGCGCCTCCACAGAGCGCCCCGTGGACGAACTGCTGCCCTTCACGCTGATCCACCGCGCCTCGACGGCGCC
GCCGCCTCGCTAG

Upstream 100 bases:

>100_bases
AGGGCTGGCAGCGCTTTCAATCGAGGAGTTTCCTTCCTCCGCCTAGACGCACTAGGCTGTCTGCGATGGGCATGAGTCTC
AAGGAAGTCGGGGCCAACGA

Downstream 100 bases:

>100_bases
GGCAACCGCCAAGCCTCAGTCAAACGCCGAGTGGCCTTGCTGATCAGCGCCCGGGACGGGCGAAAGCGGCGACGCGCGCG
CGGGCGGCGTGCACGGGATT

Product: LacI family transcription regulator

Products: NA

Alternate protein names: Catabolite control protein [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MSSVTIYDVAAKAGVSIKTVSRVMNNEPNVRPVMRERVLAAAGELGYSPNLSARSLAGSRSFVIAVFVDAALTIDHWQSE
RGADYLSRIQLGATLVCRDAGYHLLIELIDHEGPQVRQEVAALLAALKPDGVILTPPSSDNAVVLELLDRAGTPYVRVGP
ERAEGLGPRVHMDDVAAAREMTDHLIGLGHKRIGFIVGEPRYGASQARRDGYLEAMRAKGLSVPEFWVRQGDFTFQSGLE
QAKALLALPERPTAIFASNDDMALGAIAAIADAGLMTPGDVSVAGFDDSPSSRFSRPQLTTVRQPVAEMSSVAAKLLIER
SRGGASTERPVDELLPFTLIHRASTAPPPR

Sequences:

>Translated_350_residues
MSSVTIYDVAAKAGVSIKTVSRVMNNEPNVRPVMRERVLAAAGELGYSPNLSARSLAGSRSFVIAVFVDAALTIDHWQSE
RGADYLSRIQLGATLVCRDAGYHLLIELIDHEGPQVRQEVAALLAALKPDGVILTPPSSDNAVVLELLDRAGTPYVRVGP
ERAEGLGPRVHMDDVAAAREMTDHLIGLGHKRIGFIVGEPRYGASQARRDGYLEAMRAKGLSVPEFWVRQGDFTFQSGLE
QAKALLALPERPTAIFASNDDMALGAIAAIADAGLMTPGDVSVAGFDDSPSSRFSRPQLTTVRQPVAEMSSVAAKLLIER
SRGGASTERPVDELLPFTLIHRASTAPPPR
>Mature_349_residues
SSVTIYDVAAKAGVSIKTVSRVMNNEPNVRPVMRERVLAAAGELGYSPNLSARSLAGSRSFVIAVFVDAALTIDHWQSER
GADYLSRIQLGATLVCRDAGYHLLIELIDHEGPQVRQEVAALLAALKPDGVILTPPSSDNAVVLELLDRAGTPYVRVGPE
RAEGLGPRVHMDDVAAAREMTDHLIGLGHKRIGFIVGEPRYGASQARRDGYLEAMRAKGLSVPEFWVRQGDFTFQSGLEQ
AKALLALPERPTAIFASNDDMALGAIAAIADAGLMTPGDVSVAGFDDSPSSRFSRPQLTTVRQPVAEMSSVAAKLLIERS
RGGASTERPVDELLPFTLIHRASTAPPPR

Specific function: Transcriptional regulator involved in both the repression of carbohydrate utilization genes such as the alpha- amylase (amyE) and the acetyl-coenzyme A synthetase (acsA); and in the positive regulation of genes involved in excretion of excess carbon such

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lacI-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790369, Length=323, Percent_Identity=33.4365325077399, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1788474, Length=344, Percent_Identity=32.8488372093023, Blast_Score=149, Evalue=2e-37,
Organism=Escherichia coli, GI1786540, Length=362, Percent_Identity=30.939226519337, Blast_Score=144, Evalue=1e-35,
Organism=Escherichia coli, GI1790194, Length=317, Percent_Identity=30.9148264984227, Blast_Score=142, Evalue=2e-35,
Organism=Escherichia coli, GI1787948, Length=317, Percent_Identity=30.9148264984227, Blast_Score=139, Evalue=3e-34,
Organism=Escherichia coli, GI1789068, Length=305, Percent_Identity=30.8196721311475, Blast_Score=132, Evalue=4e-32,
Organism=Escherichia coli, GI1789456, Length=347, Percent_Identity=31.700288184438, Blast_Score=128, Evalue=5e-31,
Organism=Escherichia coli, GI1789202, Length=354, Percent_Identity=32.2033898305085, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI48994940, Length=337, Percent_Identity=29.9703264094956, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1787580, Length=327, Percent_Identity=27.217125382263, Blast_Score=117, Evalue=9e-28,
Organism=Escherichia coli, GI1790715, Length=338, Percent_Identity=24.2603550295858, Blast_Score=88, Evalue=9e-19,
Organism=Escherichia coli, GI1787906, Length=328, Percent_Identity=25.9146341463415, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790689, Length=345, Percent_Identity=27.8260869565217, Blast_Score=82, Evalue=7e-17,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006377
- InterPro:   IPR000843
- InterPro:   IPR010982
- InterPro:   IPR001761 [H]

Pfam domain/function: PF00356 LacI; PF00532 Peripla_BP_1 [H]

EC number: NA

Molecular weight: Translated: 37510; Mature: 37379

Theoretical pI: Translated: 6.41; Mature: 6.41

Prosite motif: PS00356 HTH_LACI_1 ; PS50932 HTH_LACI_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSVTIYDVAAKAGVSIKTVSRVMNNEPNVRPVMRERVLAAAGELGYSPNLSARSLAGSR
CCCEEEEEEHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCC
SFVIAVFVDAALTIDHWQSERGADYLSRIQLGATLVCRDAGYHLLIELIDHEGPQVRQEV
CEEEEEEECHHHHHHHHCCCCCHHHHHHHHHCCEEEEECCCCEEEHHHHHCCCHHHHHHH
AALLAALKPDGVILTPPSSDNAVVLELLDRAGTPYVRVGPERAEGLGPRVHMDDVAAARE
HHHHHHCCCCCEEECCCCCCCHHHHHHHHHCCCCEEEECCHHHHCCCCCCCHHHHHHHHH
MTDHLIGLGHKRIGFIVGEPRYGASQARRDGYLEAMRAKGLSVPEFWVRQGDFTFQSGLE
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHH
QAKALLALPERPTAIFASNDDMALGAIAAIADAGLMTPGDVSVAGFDDSPSSRFSRPQLT
HHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHCCCCCHH
TVRQPVAEMSSVAAKLLIERSRGGASTERPVDELLPFTLIHRASTAPPPR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
SSVTIYDVAAKAGVSIKTVSRVMNNEPNVRPVMRERVLAAAGELGYSPNLSARSLAGSR
CCEEEEEEHHHCCCHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCCCCCCCCHHHHCCCC
SFVIAVFVDAALTIDHWQSERGADYLSRIQLGATLVCRDAGYHLLIELIDHEGPQVRQEV
CEEEEEEECHHHHHHHHCCCCCHHHHHHHHHCCEEEEECCCCEEEHHHHHCCCHHHHHHH
AALLAALKPDGVILTPPSSDNAVVLELLDRAGTPYVRVGPERAEGLGPRVHMDDVAAARE
HHHHHHCCCCCEEECCCCCCCHHHHHHHHHCCCCEEEECCHHHHCCCCCCCHHHHHHHHH
MTDHLIGLGHKRIGFIVGEPRYGASQARRDGYLEAMRAKGLSVPEFWVRQGDFTFQSGLE
HHHHHHHCCCCCEEEEECCCCCCHHHHHHHHHHHHHHHCCCCCCHHHHHCCCCHHHHHHH
QAKALLALPERPTAIFASNDDMALGAIAAIADAGLMTPGDVSVAGFDDSPSSRFSRPQLT
HHHHHHCCCCCCCEEEECCCCCHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHCCCCCHH
TVRQPVAEMSSVAAKLLIERSRGGASTERPVDELLPFTLIHRASTAPPPR
HHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8200532 [H]