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The map label for this gene is mtnN [H]

Identifier: 16126505

GI number: 16126505

Start: 2462444

End: 2463343

Strand: Direct

Name: mtnN [H]

Synonym: CC_2266

Alternate gene names: 16126505

Gene position: 2462444-2463343 (Clockwise)

Preceding gene: 16126504

Following gene: 16126506

Centisome position: 61.3

GC content: 67.56

Gene sequence:

>900_bases
ATGCGCCTGCCCGCCCTCGTCCTCGCCTTCATCGCCCTGCTGGTCTCGCCCGCCTGGGCCCAGCGACTGGACGAGACGCC
GCGCGTGGCGGTCATCTCGGCCTTTCCGCCGGAAATCGGCGCGCTGAACGCCGCCACCGCCGAACAGAAGGCCTATGAGG
TCAACGGCGTGCGGTTCATGACCGGCAAGCTCGAGGGCAAACCGGTCGTGGTGTTCCTGAGCGGGGTGTCGATGGTCAAC
GCGGCCATGACCACCCAGATGGCGCTGGAGCGTTTCAACATCACGCGGATCGTTTTCTCGGGCATCGCCGGCGGCGTCGA
CGAGAGCCTCGACATCGGCGACGTTGTGGTCGCCGACCAGTGGGCTCAGAACCTGGAAAGCGCCTTCGCGCGCGAGACCG
ACAAGGGCTTCGAGGTCTCGCCCAGCATCCGCACGACGACCCTGGCCAACTACGGCATGATCTTTCCGCGCGGTATCCAC
ATGCCGGGCGATGCCCTGGGAGCGCCCGCGCGCGTTTGGTTCCCAACCGATCCGATCCTGCTGGATACCGCCCGCAAGGT
GGCCGCCGATGTCGCCCTGCAGCGCTGCGCGGCCGACAAGTGCCTGGTTCACCCGCCGAAGGTCGTGATCGGCGGCAACG
GCGTCTCGGCCTCGGTGTTCCTGGACAACGCCGCCTATCGCAAATACCTGCGCGCCACCTTCGAGGCCCGGGTGGTCGAC
ATGGAAAGCGCGGCCGTCGCCCACGTGGCGCTGGTCAACAAGACCCCGTTCATCGCCTTCCGCAGCCTGTCGGACCTGGC
CGGCGGCGGCGCGGGCGACAATGAGATGCACACCTTCATGGCCCTGGCCTCGGACAACTCGGCTACGGTGGTGAAGGCGT
TCGTCAGGGCGCTGCCCTAA

Upstream 100 bases:

>100_bases
GCTGATCATCCCGGGCGTAGCGGCCGCGTCGGGGCGCCCTACCCCTTGGGCCAAGTCCGACGGAGGGGTAAGCAGGCATC
GTTAGACTCAAGGACCCGCC

Downstream 100 bases:

>100_bases
ACTCCCCAACACCCTGAGTTCAGACCCCGGAGGAGCAAACCATGTCGTCTTTCGATCGCCGCGTCCTGATCTCGGGCGCC
CTCGTAGCCGGCGCGACTCT

Product: phosphorylase family protein

Products: NA

Alternate protein names: 5'-methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MRLPALVLAFIALLVSPAWAQRLDETPRVAVISAFPPEIGALNAATAEQKAYEVNGVRFMTGKLEGKPVVVFLSGVSMVN
AAMTTQMALERFNITRIVFSGIAGGVDESLDIGDVVVADQWAQNLESAFARETDKGFEVSPSIRTTTLANYGMIFPRGIH
MPGDALGAPARVWFPTDPILLDTARKVAADVALQRCAADKCLVHPPKVVIGGNGVSASVFLDNAAYRKYLRATFEARVVD
MESAAVAHVALVNKTPFIAFRSLSDLAGGGAGDNEMHTFMALASDNSATVVKAFVRALP

Sequences:

>Translated_299_residues
MRLPALVLAFIALLVSPAWAQRLDETPRVAVISAFPPEIGALNAATAEQKAYEVNGVRFMTGKLEGKPVVVFLSGVSMVN
AAMTTQMALERFNITRIVFSGIAGGVDESLDIGDVVVADQWAQNLESAFARETDKGFEVSPSIRTTTLANYGMIFPRGIH
MPGDALGAPARVWFPTDPILLDTARKVAADVALQRCAADKCLVHPPKVVIGGNGVSASVFLDNAAYRKYLRATFEARVVD
MESAAVAHVALVNKTPFIAFRSLSDLAGGGAGDNEMHTFMALASDNSATVVKAFVRALP
>Mature_299_residues
MRLPALVLAFIALLVSPAWAQRLDETPRVAVISAFPPEIGALNAATAEQKAYEVNGVRFMTGKLEGKPVVVFLSGVSMVN
AAMTTQMALERFNITRIVFSGIAGGVDESLDIGDVVVADQWAQNLESAFARETDKGFEVSPSIRTTTLANYGMIFPRGIH
MPGDALGAPARVWFPTDPILLDTARKVAADVALQRCAADKCLVHPPKVVIGGNGVSASVFLDNAAYRKYLRATFEARVVD
MESAAVAHVALVNKTPFIAFRSLSDLAGGGAGDNEMHTFMALASDNSATVVKAFVRALP

Specific function: Responsible for cleavage of the glycosidic bond in both 5'-methylthioadenosine (MTA) and S-adenosylhomocysteine (SAH) [H]

COG id: COG0775

COG function: function code F; Nucleoside phosphorylase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the PNP/UDP phosphorylase family. MtnN subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010049
- InterPro:   IPR018017
- InterPro:   IPR000845 [H]

Pfam domain/function: PF01048 PNP_UDP_1 [H]

EC number: =3.2.2.9 [H]

Molecular weight: Translated: 31807; Mature: 31807

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRLPALVLAFIALLVSPAWAQRLDETPRVAVISAFPPEIGALNAATAEQKAYEVNGVRFM
CCCHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHEEECCEEEE
TGKLEGKPVVVFLSGVSMVNAAMTTQMALERFNITRIVFSGIAGGVDESLDIGDVVVADQ
EEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHH
WAQNLESAFARETDKGFEVSPSIRTTTLANYGMIFPRGIHMPGDALGAPARVWFPTDPIL
HHHHHHHHHHHCCCCCCEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCH
LDTARKVAADVALQRCAADKCLVHPPKVVIGGNGVSASVFLDNAAYRKYLRATFEARVVD
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHEEEE
MESAAVAHVALVNKTPFIAFRSLSDLAGGGAGDNEMHTFMALASDNSATVVKAFVRALP
CCHHHEEEEEEECCCCEEEEHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCC
>Mature Secondary Structure
MRLPALVLAFIALLVSPAWAQRLDETPRVAVISAFPPEIGALNAATAEQKAYEVNGVRFM
CCCHHHHHHHHHHHHCCHHHHHCCCCCCEEEEEECCCCCCCCCCCHHHHHHEEECCEEEE
TGKLEGKPVVVFLSGVSMVNAAMTTQMALERFNITRIVFSGIAGGVDESLDIGDVVVADQ
EEECCCCEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCEEEHHH
WAQNLESAFARETDKGFEVSPSIRTTTLANYGMIFPRGIHMPGDALGAPARVWFPTDPIL
HHHHHHHHHHHCCCCCCEECCCCEEEEECCCCCCCCCCCCCCCCCCCCCEEEECCCCCCH
LDTARKVAADVALQRCAADKCLVHPPKVVIGGNGVSASVFLDNAAYRKYLRATFEARVVD
HHHHHHHHHHHHHHHHHCCCCCCCCCEEEECCCCCEEEEEECCHHHHHHHHHHHHHEEEE
MESAAVAHVALVNKTPFIAFRSLSDLAGGGAGDNEMHTFMALASDNSATVVKAFVRALP
CCHHHEEEEEEECCCCEEEEHHHHHHCCCCCCCCCCEEEEEEECCCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12788972 [H]